检索结果-南通市图书馆

Trends of Oral Cancer Mortality in China from 1990 to 2019 and a 15-Year Predictive Analysis Based on a Bayesian Age-Period-Cohort Model

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Biomedical and Environmental Sciences 2023年第6期36卷 553-556页

作者： gu jian Chang SONG Ji Wu LIU Yun WANG Xiao Lan XU Shuang Shuang ZHANG Liang Liang LIU Yun Xia DING Gang School of Stomatology Weifang Medical UniversityWeifang 261053ShandongChina Department of Stomatology Weifang People’s HospitalFirst Affiliated Hospital of Weifang Medical UniversityWeifang 261053ShandongChina Department of Dentistry Affiliated Hospital of Weifang Medical UniversityWeifang 261035ShandongChina

Oral cancer is the most common malignant tumor of the head and *** is characterized by high rates of recurrence and distant metastasis and usually has a poor *** advances in cancer diagnosis and treatment,the overall ... 详细信息

关键词： diagnosis cancer Cancer

Human CD39hi regulatory T cells present stronger stability and function under inflammatory conditions

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2017年第6期14卷 521-528页

作者： jian gu Xuhao Ni Xiongxiong Pan Hao Lu Yunjie Lu Jie Zhao Song guo Zheng Keli L Hippen Xuehao Wang Ling Lu Translational Medicine Research Center Affiliated Jiangning Hospital and Liver Transplantation Center First Affiliated Hospital Nanjing Medical University Nanjing 210029 China University of Minnesota Cancer Center and Division of Bone Marrow Transplantation Department of Pediatrics University of Minnesota Minneapolis MN 55455 USA Division of Rheumatology Penn State Milton S. Hershey Medical Center Hershey PA 17033 USA

Autoimmune diseases are characterized by an imbalance between regulatory T cells and effector T-cell subsets, such as Thl and Th17 cells. Studies have confirmed that natural CD4＋Foxp3＋ Tregs were unstable and dysfunctional in the presence of pro-inflammatory cytokines. In the current study, human CD39hi Tregs and CD39low Tregs were sorted from Tregs in vitro after 7 days of expansion. The functions of both Treg subsets were investigated under inflammatory conditions in vitro and in vivo. In the presence of IL-1β and IL-6, cultured CD4＋CD39hi Tregs maintained stable forkhead box protein 3 expression, whereas CD4＋CD39low Tregs lost Foxp3 expression and trans-differentiated into Thl or Th17 cells. Decreased IL-1βR and IL-6R expression on the CD39hi Tregs was the primary mechanism responsible for Treg stability. In addition, reduced activation of downstream molecules, such as STAT1 and STAT3, through the modulation of CpG demethylation played an important role. Finally, human CD4＋CD39hi Tregs but not CD4＋CD39low Tregs protected against xenograft versus host disease in model mice. These results strongly implied the physiological importance of CD39 expression and suggested that manipulation of CD39hi Tregs might represent a novel strategy for the treatment of autoimmune diseases.

关键词： CD39 stability Tregs xeno-GVHD

KINETIC STUDY ON THE EXTRACTION OF PALLADIUM(Ⅱ) WITH BIS(2-ETHYLHEXYL)SULFIDE

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1992年第6期3卷 463-464页

作者： jian Sheng gu jian Hua PAN Han Zhang WANG Department of Chemistry, Suzhou University, Suzhou, 215006

The effects of concentration, temperature, stirring rate and specific interfacial area on the extraction of Pd (Ⅱ) with bis(2--ethylhexyl) sulfide (DEHS) were studied by the use of a constant interracial area cell. T... 详细信息

关键词： WITH BIS ETHYLHEXYL)SULFIDE KINETIC STUDY ON THE EXTRACTION OF PALLADIUM

Level Statistics for the Nilsson Single-Particle Levels

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2010年第3期27卷 52-55页

作者：陈芳祁周先荣顾建中 Department of Physics and Institute of Theoretical Physics and Astrophysics Xiamen University Xiamen 361005 China Institute of Atomic Energy P.O. Box 275(18) Beijing 102413

We perform level statistics of the Nilsson single-particle levels. The effects of the l2 and l ＆#12539; s; s terms are discussed as well as their interplay with the deformations. The results show that when the l2 term is added to the harmonic oscillator potential, chaotic motion occurs. The strength ranges of the l2 term in which chaotic motion exists are related to the deformation of the harmonic oscillator potential. The calculations of the localization length in different bases demonstrate that it is the spherical or axial symmetries that govern the chaotic motion. The degree of chaoticity increases significantly with the l ＆#12539; s; s term included.

关键词： Periodicity Statistics Levels

Positive Regulation of Phytochrome B on Chlorophyll Biosynthesis and Chloroplast Development in Rice

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rice science 2013年第4期20卷 243-248页

作者： ZHAO Jie ZHOU Jin-jun WANG Ying-ying gu jian-wei XIE Xian-zhi Shandong Rice Research Institute College of Life Sciences Shandong Normal University

Phytochromes in rice are encoded by a gene family composed of three members, PHYA, PHYB, and PHYC. Through characterizing the phytochrome mutants and wild type （WT） in terms of photomorphogenesis, roles of individual phytochromes have been preliminarily explored in regulating rice de-etiolation, flowering time and fertility. However, little information has been reported about whether or how phytochromes affect chlorophyll biosynthesis and chloroplast development in rice. In this study, we compared the chlorophyll contents of wild type and the phyA, phyB and phyAphyB mutants grown under either white light （WL） or red light （R）. The results suggest that phyB perceives R to positively regulate chlorophyll biosynthesis, while the role of phyA can be detected only in the phyB-deficient mutant. Analyses of the expression levels of genes involved in chlorophyll biosynthesis revealed that phytochromes affected the chlorophyll biosynthesis by regulating protochlorophyll oxidoreductase A （PORA） expression. The role of phyB in chloroplast development was also analyzed, and the results suggest that phyB perceives R to regulate chloroplast development by affecting the numbers of chloroplasts and grana, as well as the chloroplast membrane system.

关键词： rice -phytochrome chlorophyll biosynthesis protochlorophyll oxidoreductase A chloroplastdevelopment

基于隶属函数法对不同材料膜覆盖花生影响评价

在线全文

学校读者我要写书评

暂无评论

辽宁农业科学 2024年第4期 40-43页

作者：蔡立夫谷健肖猛梁志鹏高庆新韩宝刚辽宁省沙地治理与利用研究所辽宁阜新123000 中国科学院沈阳应用生态研究所辽宁沈阳110016 阜新蒙古族自治县住房和城乡建设服务中心辽宁阜新123100 阜新蒙古族自治县塔营镇农业综合服务中心辽宁阜新123111 阜新蒙古族自治县现代农业发展服务中心辽宁阜新123000

利用隶属函数法对不同材料膜覆盖下的花生生长影响进行了评价,结果表明,形态学方面,塑料地膜覆盖效果最优,纤维黑色纸膜次之,对照(无覆盖)最差;光合方面,液态生物降解膜覆盖效果最优,粉剂生物降解膜次之,对照最差;水分利用方面,粉剂生... 详细信息

利用隶属函数法对不同材料膜覆盖下的花生生长影响进行了评价,结果表明,形态学方面,塑料地膜覆盖效果最优,纤维黑色纸膜次之,对照(无覆盖)最差;光合方面,液态生物降解膜覆盖效果最优,粉剂生物降解膜次之,对照最差;水分利用方面,粉剂生物降解膜覆盖效果最优,液态生物降解膜次之,对照最差;产量方面,粉剂生物降解膜效果最佳,塑料地膜和液态生物降解膜次之,对照亦最差。隶属函数法可以解决同类间不同指标所得的结论不一致的矛盾,可以准确反映出不同材料膜覆盖对花生生长的影响。

关键词：隶属函数综合评价不同材料膜覆盖花生

维普期刊数据库博看期刊

A new portable open-path instrument for ambient NH_(3) and on-road emission measurements

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2024年第2期136卷 606-614页

作者： Wenhao Dai Shanshan Wang Sanbao Zhang jian Zhu Chuanqi gu Zhibin Sun Ruibin Xue Bin Zhou Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention(LAP3) Department of Environmental Science and EngineeringFudan UniversityShanghai 200438China Institute of Eco-Chongming(IEC) Shanghai 202162China Institute of Atmospheric Sciences Fudan UniversityShanghai 200433China

Increased attentions to vehicle emission of NH_(3)have been paid since it is generally regarded as an important source in urban ***,we developed a movable instrument based on Differential Optical Absorption Spectroscopy(DOAS)principle for detecting on-road NH_(3),which can avoid the losses in the sampling process attributed to the non-sampling *** this mobile DOAS,the temporal resolution,detection limit and relative error for NH_(3)were 1 min,2.29 ppbv and 4.57%±2.44%,*** employed to the on-road measurements along the arterial highway in Shanghai,the spatial distributions of NH_(3)and NO were obtained,and their dependence of traffic and road conditions were *** slopes of linear regression between NH_(3)and NO were 0.40,0.02 and 0.07 on the Middle Ring Road,Outer Ring Road and Chongming Island Ring *** indicates that light gasoline vehicles(LGVs)were found to be the main contributor to NH_(3)emissions,while heavy-duty diesel vehicles(HDVs)mainly emitted *** on the measured NH_(3)in the tunnel,the mileagebased NH_(3)emission factor per vehicle was estimated to be 17.9±6.3 mg/*** reported open-path instrument can be broadly used in on-road pollutant monitoring or vehicle emissions,and the measurements can reveal the real situation of emission characteristics,even find the abnormal operations of vehicle catalyst system.

关键词： Ammonia Traffic emissions DOAS Emission factor Mobile measurements

Synthesis of Substituted Indolizines via Radical Oxidative Decarboxylative Annulation of 2 (Pyridin-2-yl)acetate Derivatives withα,β-Unsaturated Carboxylic Acids

在线全文

学校读者我要写书评

暂无评论

Synthesis of Substituted Indolizines via Radical Oxidative D...

2016年全国功能精细化学品绿色制造及应用技术交流会

作者： jian gu Chun Cai Chemical Engineering College Nanjing University of Science and Technology

A copper mediated radical oxidative annulation of 2-(pyridin-2-yl)acetate derivatives with α,β-unsaturated carboxylic acids is *** study offers a new and expedient strategy for synthesis of

关键词： Indolizines Decarboxylative Radical Oxidative Annulation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

基于微观渗流机理的宏观油藏数值模拟研究

中国石油大学学报（自然科学版） 2006年第1期30卷 77-81,85页

作者：谷建伟中国石油大学石油工程学院山东东营257061

处于高含水开发期油藏的剩余油分布主要受流体性质和岩石孔隙结构的影响,而经典数值模拟并没有考虑微观孔喉特征的影响。为此建立了描述微观孔喉特征的地层孔隙网络模型,并对构成网络的基本连线单元进行改进,使网络模型能更细致地描述... 详细信息

处于高含水开发期油藏的剩余油分布主要受流体性质和岩石孔隙结构的影响,而经典数值模拟并没有考虑微观孔喉特征的影响。为此建立了描述微观孔喉特征的地层孔隙网络模型,并对构成网络的基本连线单元进行改进,使网络模型能更细致地描述油水分布特征和水驱油微观机理。利用逾渗理论计算了基于微观渗流机理的相对渗透率曲线,并将其应用到经典数值模拟计算中,实现了微观渗流机理与宏观数值模拟计算的结合。实例分析表明,利用该数值模拟计算方法得到的基于微观特征的剩余油分布更符合地下实际流体分布,其结果可为调剖堵水、化学驱提供技术参数。

关键词：微观渗流机理逾渗理论网络模型剩余油分布高含水开发期宏观油藏数值模拟