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Acta Geologica Sinica(English Edition) 2015年第A2期89卷 44-46页

作者： lian Dongyang YANG Jingsui LIU Fei DING Yi WU Weiwei ZHAO Hui ZHANG Li huang jian Faculty of Earth Sciences China University of Geosciences Wuhan 430074 China CARMA State Key Laboratory for Continental Tectonics and Dynamics Institute of Geology Chinese Academy ofGeological Sciences Beijing 100037 China School of Earth Science and Mineral Resources China University of Geosciences Beijing 100083 China

Ophiolites, mostly found in orogenic belts, represent fragments of palaeo-oceanic lithosphere emplaced on the continent through tectonic processes （Bizimis et al., 2000; Dilek and Fumes, 2011, 2014; Pearce, 2014）. T... 详细信息

关键词： Peridotite Ophiolites Mineralogy Petrology Geochemistry

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直埋热水供热管道泄漏声波特性实验研究

科学技术与工程 2024年第11期24卷 4711-4721页

作者：徐自强李成穆连波王随林鲁军辉刘建军北京建筑大学环境与能源工程学院北京100044 北京京大深能科技有限公司北京100037 北京市热力集团有限公司北京100028

城市直埋供热管网泄漏精准智能定位是城市供热基础设施安全与节能降碳及智能化运行的关键环节。为提高利用声波法进行直埋热水供热管网泄漏的定位精度,建立DN300管径的大型模化供热实验系统,研究了有无泄漏时,管壁上声波信号随传播距离... 详细信息

城市直埋供热管网泄漏精准智能定位是城市供热基础设施安全与节能降碳及智能化运行的关键环节。为提高利用声波法进行直埋热水供热管网泄漏的定位精度,建立DN300管径的大型模化供热实验系统,研究了有无泄漏时,管壁上声波信号随传播距离、温度、压力和流量变化的特性,分析了管道上水泵振动声波的时频特点,然后利用小波阈值法进行信号降噪,得到了供热管道泄漏的特征频段。研究表明,温度对泄漏声波频段影响显著,温度越高声波特征频段分布越大,温度从31℃升高到86℃后,特征频段从200~800 Hz扩展至50~1500 Hz;传播距离、压力和流量主要影响泄漏信号幅值,对特征频段范围影响较小;水泵声波能量主要集中在3000~4000 Hz处于泄漏信号频段范围之外。利用小波阈值法进行信号降噪,提高定位精度可达0.11%,实现定位距离偏差在±1 m内。

关键词：声波法热水供热管道泄漏检测降噪定位

Photoexcited CRYPTOCHROME 1 Interacts Directly with G-Protein 13 Subunit AGB1 to Regulate the DNA-Binding Activity of HY5 and Photomorphogenesis in Arabidopsis

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Molecular Plant 2018年第10期11卷 1248-1263页

作者： Hongli lian Pengbo Xu Shengbo He Jun Wu jian Pan Wenxiu Wang Feng Xu Sheng Wang Junsong Pan Jirong huang Hong-Quan Yang School of Agriculture and Biology Shanghai Jiao Tong University Shanghai 200240 China School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai 200240 China College of Life and Environmental Sciences Shanghai Normal University Shanghai 200234 China State Key Laboratory of Genetic Engineering Collaborative Innovation Center for Genetics and Development School of Life Sciences Fudan University Shanghai200438 China These authors contributed equally to this article.

Light and the heterotrimeric G-protein are known to antagonistically regulate photomorphogenesis in Arabidopsis. However, whether light and G-protein coordinate the regulation of photomorphogenesis is largely unknown. Here we show that the blue light photoreceptor cryptochrome 1 （CRY1） physically inter-acts with the G-protein β subunit, AGB1, in a blue light-dependent manner. We also show that AGB1 directly interacts with HY5, a basic leucine zipper transcriptional factor that acts as a critical positive regulator of photomorphogenesis, to inhibit its DNA-binding activity. Genetic studies suggest that CRY1 acts partially through AGB1, and AGB1 acts partially through HY5 to regulate photomorphogenesis. Moreover, we demonstrate that blue light-triggered interaction of CRY1 with AGB1 promotes the dissociation of HY5 from AGB1. Our results suggest that the CRY1 signaling mechanism involves positive regulation of the DNA-binding activity of HY5 mediated by the CRY1-AGB1 interaction, which inhibits the association of AGB1 with HY5. We propose that the antagonistic regulation of HY5 DNA-binding activity by CRY1 and AGB1 may allow plants to balance light and G-protein signaling and optimize photomorphogenesis.

关键词： Arabidopsis cryptochrome heterotrimeric G-protein β subunit AGB1 HY5 photomorphogenesis

Impact of hydrothermal process on the nutrient ingredients of restaurant garbage

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Journal of Environmental Sciences 2006年第5期18卷 1012-1019页

作者： REN lian-hai NIE Yong-feng LIU jian-guo JIN Yi-ying Sun Lu Department of Environmental Science and Engineering Tsinghua University Beijing 100084 China Department of Chemical and Environmental Engineering Beijing Technology and Business University Beijing 100037 China Department of Environmental Engineering China Agricultural University Beijing 100094 China

In order to recover the nutrient resource from restaurant garbage, a complete trial with 2 factors on 5 levels of experiments was carried out. The temperature and heating time are the main factors influencing on hydrothermal process （HP） by which improves the degradability and digestibility of the restaurant garbage favorably to make animal feeds or fertilizer. The results showed the variation of protein, saccharide, and oil in the garbage. It showed that protein dissolved and liquefied during hydrothermal process, which made organic nitrogen in solid phase transfer to liquid phase. After heating at 180℃ for 60min, organic nitrogen in liquid phase began to transform into ammonia. It also showed that hydrothermal process could promote the dextrinization, dissolution of the starch and its hydrolysis to reducing sugar, due to that starch in the restaurant garbage decreases and reducing sugar increases. When the temperature reached 140℃, the reducing sugar started to decrease due to chemical reactions. The cellulose was stable at 100-180℃. The floatable oil increased markedly in the hydrothermal process. The suitable condition for de-oil was observed at 160℃ heating for 80 min. Furthermore, the extraction of grease from the solid phase accords with first-order reaction dynamic model.

关键词： restaurant garbage hydrothermal process protein saccharide lipid

Effects of retrorsine on mouse hepatocyte proliferation after liver injury

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World Journal of Gastroenterology 2006年第9期12卷 1439-1442页

作者： Xiao-Fei Zhou Qian wang jian-xin Chu Ai-lian Liu Centerfor Developmental Biology Xinhua Hospital Shanghai JiaotongUniversity School of Medicine Shanghai 200092 China

AIM： To study the effect of retrorsine on mouse hepatocyte proliferation. METHODS： Mice and rats were treated respectively with two injections of retrorsine （as retrosine-treated group） or saline （as non-treated group） at 2 wk intervals. They received a single injection of carbon tetrachloride （CCh） 4 wk later. On d 0, 1, 2, 3, 4, 6, 15 after CCh administration, the animals were killed and their livers were excised. Hematoxylin and eosin （HE） staining and Ki-67 antibody immunohistochemical analysis of liver samples were used to evaluate the pathological changes and hepatocyte proliferation. RESULTS： In rats treated with retrorsine and CCl4, the liver displayed obvious megalocytosis, proliferation of mild bile duct, small hepatocyte-forming nodule, which were not found in liver samples from non-treated group. However, in mice treated with retrorsine combined with CCh, the liver displayed hepatocyte degeneration and necrosis in perivenous areas. There was no obvious difference between retrorsine-treated group and nontreated group. Ki-67 immunohistochemical analysis showed that in rats treated with retrorsine, the positive hepatocytes mainly found in small hepatocyte nodules, were obviously less than those in non-treated group. The mice treated with retrorsine showed that the number of Ki-67 positive hepatocytes was very high and more than that in non-treated group. CONCLUSION： Retrorsine has no effect on mouse hepatocyte proliferation.

关键词： Retrorsine House Rat Hepatocyte proliferation

Preparation of Highly Active Pt-K/γ-Al_2O_3 Catalyst for o-Phenylphenol Synthesis from o-Cyclohexenyl-cyclohexanone Dehydrogenation

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Chemical Research in Chinese Universities 2008年第6期24卷 726-730页

作者： DING Jie-lian LIN Ling XU jian-dong ZENG Chong-yu College of Chemistry and Chemical Engineering Nanjing University of Technology Nanjing 210009 P R. China

0.5%Pt-K/γ-Al2O3 catalysts for the synthesis of o-phenylphenol（OPP） from o-cyclohexenyl-cyclohexanone （dimer） dehydrogenation were prepared by means of a two subsequent impregnation method. The effects of catalyst preparation parameters, such as K promoters, calcination, and reduction conditions, were investigated. The results showed that the addition of K2SO4 to Pt/γ-Al2O3 catalyst notably promoted the selectivity of OPP, and its optimum content was found to be 6% in mass fraction. The higher activity was obtained when Pt/γ-Al2O3 catalyst was calcined in nitrogen atmosphere at 400--500 ℃ and then reduced at the same temperature for 3 h in hydrogen atmosphere. The conversion of the dimer and the selectivity of OPP were always above 99% and 90%, respectively, over 0.5%Pt-6% K2SO4/γ-Al2O3 catalyst during the pilot scale test of 8000 h.

关键词： o-Phenylphenol Pt catalyst K promoters Calcinations Reduction

Influence of Vanadium on Fracture Splitting Property of Medium Carbon Steel

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Journal of Iron and Steel Research International 2016年第5期23卷 475-483页

作者： Wei-jun HUI Cheng-wei SHAO Yong-jian ZHANG Si-lian CHEN Han DONG School of Mechanical Electronic and Control Engineering Beijing Jiaotong University Beijing 100044 China Central Iron and Steel Research Institute Beijing 100081 China

The fracture splitting property of medium carbon steel 37MnSiS microalloyed with V up to 0. 45% was investigated by using simulated fracture splitting test,for the development of new crackable medium carbon steel to manufacture high performance connecting rod. Conventional high carbon steel C70S6 was used for comparison. The results show that the volume fraction of both ferrite and V-rich M（ C,N） particles increases,and the pearlite interlamellar spacing decreases with increasing V content,which in turn results in gradual increase of strength and decrease of ductility and impact energy. The fracture splitting property of the tested steel could be improved significantly due to the increase of V content mainly through the precipitation hardening mechanism of fine M（ C,N） precipitates. The fraction of brittle cleavage fracture in the crack initiation area increases noticeably with increasing V content and full brittle cleavage fracture surface could be obtained when V content was increased to 0. 45%. It is concluded that medium carbon steel with V content higher than about 0. 28% possesses not only comparable or even higher mechanical properties with those of conventional steel C70S6,but also excellent fracture splitting property,and therefore,is more suitable to fabricate high performance fracture splitting connecting rod.

关键词： microalloyed medium carbon steel fracture splitting vanadium precipitation hardening microstructure

地面定向钻孔预注浆掩护巷道穿断层破碎带技术应用

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建井技术 2024年第5期45卷 45-50页

作者：李连刚涂磊解建牛玛窦安徽恒源煤电股份有限公司五沟煤矿安徽淮北235000 天地科技股份有限公司北京100013

为了解F2断层发育情况,解决岩巷穿断层期间由于顶、底板及巷道围岩破碎导致的水害、断层破碎带支护问题,在分析矿区地质条件的基础上,通过实施地面L型多分支定向钻孔对巷道穿F2断层周围破碎岩体进行预注浆加固,综合运用理论计算、工程... 详细信息

为了解F2断层发育情况,解决岩巷穿断层期间由于顶、底板及巷道围岩破碎导致的水害、断层破碎带支护问题,在分析矿区地质条件的基础上,通过实施地面L型多分支定向钻孔对巷道穿F2断层周围破碎岩体进行预注浆加固,综合运用理论计算、工程效果监测分析等方法,对巷道掘进期间的围岩塑性圈范围进行了理论分析研究;实测分析了F2断层地面区域治理工程注浆前后地层单位吸水量变化及注浆效果。结果表明,地面定向钻孔高压预注浆有效提升了巷道围岩稳定性,研究成果为类似地层条件下巷道的安全、高效掘进提供了实践经验。

关键词： F2断层断层破碎带巷道围岩定向钻孔注浆加固

左西孟旦与重组人脑利钠肽联合治疗对急性心力衰竭患者血清炎性因子及心脏功能的影响

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中国实用医药 2024年第13期19卷 98-101页

作者：庄见群李莲娜盛清华日照市中心医院心内科 276800 日照市中心医院静脉药物配置中心 276800 日照市中心医院药学部 276800

目的探究左西孟旦与重组人脑利钠肽联合治疗对急性心力衰竭(AHF)患者血清炎性因子及心脏功能的影响。方法回顾性分析60例AHF患者的临床资料,根据治疗方法的不同将其分为对照组(30例)和观察组(30例)。对照组接受左西孟旦治疗,在此基础... 详细信息

目的探究左西孟旦与重组人脑利钠肽联合治疗对急性心力衰竭(AHF)患者血清炎性因子及心脏功能的影响。方法回顾性分析60例AHF患者的临床资料,根据治疗方法的不同将其分为对照组(30例)和观察组(30例)。对照组接受左西孟旦治疗,在此基础上,观察组联合重组人脑利钠肽治疗。对比两组临床效果、血清炎性因子[白介素-10(IL-10)、白介素-17(IL-17)、白介素-6(IL-6)、C反应蛋白(CRP)]、心脏功能[心脏指数(CI)、左室舒张末期内径(LVEDD)、左室射血分数(LVEF)、每搏输出量(SV)]、不良反应发生情况。结果观察组临床治疗总有效率96.67%较对照组的73.33%高(P2.94±0.48)ng/L高于对照组的(2.13±0.35)ng/L, IL-17(16.21±3.22)ng/L、IL-6(3.63±0.89)ng/L、CRP(10.18±2.07)mg/L低于对照组的(26.43±5.66)ng/L、(5.17±1.01)ng/L、(14.39±2.58)mg/L(P22±3.21)mm低于对照组的(59.39±3.85)mm,LVEF(44.94±3.42)%、CI(4.92±0.56)L/min、SV(39.22±3.15)ml高于对照组的(41.15±2.63)%、(4.43±0.34)L/min、(36.23±2.45)ml(P0.05)。结论 AHF患者应用左西孟旦联合重组人脑利钠肽治疗能够更快地调节其炎性因子水平,促进心脏功能改善,且安全性高。

关键词：急性心力衰竭左西孟旦重组人脑利钠肽血清炎性因子心脏功能

Tandem Approach to Functionalized Pyrrolo[3,4-α]carbazole-1,3-diones via a Pd-catalyzed Indole-to-carbazole Transformation

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Chemical Research in Chinese Universities 2019年第4期35卷 621-626页

作者： GUO lianghua XU Mei jian Yong LIU Sheng PAN Weidong DUAN lian State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical UniversityGuiyang 550014P. R.China

A one-pot and efficient tliree-component reaction of indoles, acrylates and maleimides for the synthesis of pyrrolo[3,4-α]carbazole-1,3-dione derivatives was developed. Three C-C bonds and one ring were created in a single step via an indole-to-carbazole transformation triggered by Pd(II)-catalyzed direct C3-alkenylation of indoles.

关键词： Carbazole One-pot Tandem reaction Three-component reaction Indole-to-carbazole