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Left jackknife position:a novel position for laparoscopic hepatectomy

Chinese Journal of Cancer 2017年第8期36卷 380-383页

作者： jian-cong Chen Rong-Xin Zhang Min-Shan Chen Li Xu Jin-Bin Chen Ke-Li Yang Yao-Jun Zhang Zhong-Guo Zhou State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer CenterGuangzhou 510060GuangdongP.R.China Department of Hepatobiliary Oncology Sun Yat-sen University Cancer Center651 Dongfeng Road EastGuangzhou 510060GuangdongP.R.China Department of Colorectal Cancer Sun Yat-sen University Cancer CenterGuangzhou 510060GuangdongP.R.China

Background: Laparoscopic hepatectomy for hepatocellular carcinoma(HCC) located in segment Ⅵ, Ⅶ, or Ⅷ of the liver is usually difficult because of poor operative exposure, due to the unique anatomical structure. In this study, we evaluated the practice of laparoscopic hepatectomy with the left jackknife position for patients with HCC located in segment Ⅵ, Ⅶ, or Ⅷ.Methods: A total of 10 patients were enrolled to undergo laparoscopic hepatectomy with the left jackknife *** located in segment Ⅵ, Ⅶ, or Ⅷ were assessed by preoperative dynamic computed tomography or magnetic resonance imaging. Operation time, intraoperative blood loss, postoperative fasting time, postoperative drainage time, major postoperative complications, and duration of postoperative hospital stay were ***: All surgeries were successfully completed. None of the patients required conversion to open surgery during the procedure, and no serious postoperative complications were *** median tumor size was 31 mm(range 23-41 mm) in diameter, the mean operation time was 166 ± 38 min, the mean intraoperative blood loss was220 ± 135 mL, and the median postoperative hospital stay was 4 days(range 2-7 days).Conclusions: For HCC located in segment Ⅵ, Ⅶ, or Ⅷ, laparoscopic hepatectomy with this novel position—the left jackknife position—is safe and effective during tumor resection by exposing a sufficient operating *** registration *** ID:

关键词： Laparoscopic hepatectomy Hepatocellular carcinoma Segment VI VII or VIII Left jackknife position

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Male gender is associated with an increased risk of anastomotic leak in rectal cancer patients after total mesorectal excision

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Gastroenterology Report 2018年第2期6卷 137-143,I0003页

作者： jian-ping Wang and Ping Lan Chi Zhou Xian-rui Wu Xuan-hui Liu Yu-feng Chen Jia Ke Xiao-wen He Xiao-sheng He Tuo Hu Yi-feng Zou Xiao-bin Zheng Hua-shan Liu jian-cong Hu Xiao-jian Wu jian-ping Wang Ping Lan Department of Colorectal Surgery the Sixth Affiliated Hospital of Sun Yat-sen UniversityGuangdong Provincial Key Laboratory of Colorectal and Pelvic Floor DiseasesGuangzhouGuangdong 510065China

Background:The impact of a patient’s gender on the development of anastomotic leak(AL)in rectal cancer patients following total mesorectal excision(TME)remains *** aim of this study was to evaluate the association between patients’gender and the risk of ***:All rectal cancer patients following TME with a primary anastomosis during the study period from 2010 to 2014 were *** of the post-operative AL incidence rate between male and female patients were ***:Of all patients examined(n¼956),587(61.4%)were males and 369(38.6%)were *** patients were more likely to have a history of smoking and drinking alcohol,but less likely to have a history of abdominal surgery compared to female patients.A higher incidence rate of pre-operative bowel obstruction and larger tumor volume in male patients was observed in our *** all the patients,81(8.5%)developed post-operative *** male patients(n¼62,10.6%)suffered from AL than females(n¼19,5.1%)(P¼0.003).Multivariate logistic regression analyses confirmed the association between male gender and AL[odds ratio(OR):2.41,95%confidence interval(CI):1.37–4.23,P¼0.002].Similar results were also obtained in patients who underwent laparoscopic TME(OR:2.11,95%CI:1.15–3.89,P¼0.016).Conclusions:Male patents were found to have an increased risk for AL following TME with a primary anastomosis.A temporary protecting stoma may help to protect the anastomosis and lessen the risk for AL especially in male patients.

关键词： rectal cancer anastomotic leak gender risk factor total mesorectal excision primary anastomosis

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Prospective,single-center cohort studyanalyzing the efficacy of complete laparoscopic resection on recurrent hepatocellular carcinoma

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Chinese Journal of Cancer 2016年第5期35卷 229-235页

作者： Jie Zhang Zhong-Guo Zhou Zhong-Xi Huang Ke-Li Yang jian-cong Chen Jin-Bin Chen Li Xu Min-Shan Chen Yao-Jun Zhang Department of Hepatobiliary Oncology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer Medicine

Background:Laparoscopic hepatectomy is increasingly being used to treat hepatocellular carcinoma(HCC).However,few studies have examined the treatment of recurrent HCC in patients who received a prior *** present prospective study compared the clinical efficacy of laparoscopic surgery with conventional open surgery in HCC patients with postoperative tumor ***:We conducted a prospective study of 64 patients,all of whom had undergone open surgery once before,who were diagnosed with recurrent HCC between June 2014 and November *** laparoscopic group(n = 31)underwent laparoscopic hepatectomy,and the control group(n = 33) underwent conventional open *** time,intraoperative blood loss,surgical margins,postoperative pain scores,postoperative time until the patient could walk,anal exsufflation time,length of hospital stay,and inpatient costs were compared between the two *** patients were followed up for 1 year after surgery,and relapse-free survival was compared between the two ***:All surgeries were successfully *** conversion to open surgery occurred in the laparoscopic group,and no serious postoperative complications occurred in either *** significant difference in inpatient costs was found between the laparoscopic group and the control group(P = 0.079),but significant differences between the two groups were observed for operation time(116.7 ± 37.5 vs.148.2 ± 46.7 min,P = 0.031),intraoperative blood loss(117.5 ± 35.5 vs.265.9 ± 70.3 mL,P = 0.012),postoperative time until the patient could walk(1.6 ± 0.6vs.2.2 ± 0.8 days,P < 0.05),anal exsufflation time(2.1 ± 0.3 vs.2.8 ± 0.7 days,P = 0.041),visual analogue scale pain score(P < 0.05),postoperative hepatic function(P < 0.05),and length of hospital stay(4.5 ± 1.3 vs.6.0 ± 1.2 days,P = 0.014).During the 1-year postoperative follow-up period,6 patients in each group had recurrent HCC on the side of the initial operation,but no significant difference

关键词：英语教学教学理念英语阅读

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Development characteristics and controlling factors of fractures in lacustrine shale and their geological significance for evaluating shale oil sweet spots in the third member of the Shahejie Formation in the Qikou Sag, Bohai Bay Basin

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Petroleum Science 2024年第2期21卷 791-805页

作者： Xu Zeng Tao Yang jian-Wei Feng cong-Sheng Bian Ming Guan Wei Liu Bing-Cheng Guo Jin Dong Research Institute of Petroleum Exploration and Development China National Petroleum CorporationBeijing100083China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China School of Earth Sciences China University of PetroleumQingdao266400ShandongChina

Natural fractures are critical for shale oil and gas enrichment and development. Due to the extremely high heterogeneity of shale, the factors controlling the formation of internal fractures, especially horizontal fractures, remain controversial. In this study, we integrate thin section analysis and microcomputed tomography(CT) data from several lacustrine shale samples from the third member(Es3) of the Shahejie Formation, Qikou Sag, Bohai Bay Basin, to assess the fractures in detail. The goal is to reveal the development characteristics, controlling factors, and geological significance for evaluating sweet spots in a shale oil play. The fractures in the Es3contain high-angle structural and horizontal bed-parallel fractures that are mostly shear and extensional. Various factors influence fracture development,including lithofacies, mineral composition, organic matter content, and the number of laminae. Structural fractures occur predominantly in siltstone, whereas bed-parallel fractures are abundant in laminated shale and layered mudstone. A higher quartz content results in higher shale brittleness, causing fractures, whereas the transformation between clay minerals contributes to the development of bedparallel fractures. Excess pore pressure due to hydrocarbon generation and expulsion during thermal advance can cause the formation of bed-parallel fractures. The density of the bed-parallel and structural fractures increases with the lamina density, and the bed-parallel fractures are more sensitive to the number of laminae. The fractures are critical storage spaces and flow conduits and are indicative of sweet spots. The laminated shale in the Es3with a high organic matter content contains natural fractures and is an organic-rich, liquid-rich, self-sourced shale play. Conversely, the siltstone, massive mudstone, and argillaceous carbonate lithofacies contain lower amounts of organic matter and do not have bed-parallel fractures. However, good reservoirs can form in th

关键词： Fractures Development characteristics Controlling factors Shale oil Sweet spot

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Clinical outcomes of fertility-sparing treatments in young patients with epithelial ovarian carcinoma

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第10期12卷 787-795页

作者： Jun HU Li-rong ZHU Zhi-qing LIANG Yuan-guang MENG Hong-yan GUO Peng-peng QU Cai-ling MA cong-jian XU Bi-bo YUAN Department of Gynecology Peking University First Hospital Beijing 100034 China Department of Gynecology Southwest Hospital of Third Military Medical University Chongqing 400038 China Department of Gynecology Chinese PLA General Hospital ＆ Chinese PLA Postgraduate Medical School Beijing 100853 China Department of Gynecology Peking University Third Hospital Beijing 100191 China Tianjin Central Obstetrics and Gynecological Hospital Tianjin 300052 China Department of Gynecology Xinjiang Medical University First Teaching Hospital Urumqi 830054 China Shanghai Red House Hospital of Obstetrics and Gynecology Shanghai 200011 China Department of Gynecology Tianjin Medical University General Hospital Tianjin 300052 China

Objective:To assess the clinical outcomes of fertility-sparing treatments in young patients with epithelial ovarian carcinoma (EOC).Methods:A retrospective study of young EOC inpatients (≤40 years old) was performed during January 1994 and December 2010 in eight ***:Data were analyzed from 94 patients treated with fertility-sparing surgery with a median follow-up time of 58.7 *** histologic grade increased,overall survival (OS) and disease-free survival (DFS) of patients receiving fertility-sparing surgery *** staging surgery nor laparoscopy of early stage EOC with conservative surgery had a significant effect on OS or *** menstruation recommenced after chemotherapy in 89% of the fertility-sparing *** pregnancies among twelve patients were achieved by the end of the ***:Fertility-sparing treatment for patients with EOC Stage I Grade 1 could be cautiously considered for young *** surgical procedure and surgical route might not significantly influence the *** chemotherapy is not likely to have an evident impact on ovarian function or fertility in young patients.

关键词： Epithelial ovarian carcinoma Fertility-sparing treatment Overall survival Disease-free survival Pregnancy

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Chinese Tuina Downregulates the Elevated Levels of Tissue Plasminogen Activator in Sciatic Nerve Injured Sprague-Dawley Rats

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Chinese Journal of Integrative Medicine 2017年第8期23卷 617-624页

作者： PAN Fan YU Tian-yuan Steven Wong XIAN Si-tong LU Meng-qian WU jian-cong GAO Yu-feng LI Xiao-qin GENG Nan YAO Bin-bin Collage of Acupuncture-Moxibustion and Tuina Beijing University of Chinese Medicine The 2nd Massage Department Beijing Massage Hospital Department of Encephalopathy of Mogol Medicine Affiliated Hospital of Inner Mongolia University for the Nationalities Department of Acupuncture and Moxibustion Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine Department of Massage Physiotherapy Beijing University of Chinese Medicine Dongfang Hospital

Objective：To elucidate the mechanism of Chinese tuina in treating sciatic nerve crush injury,and to detect the levels of tissue plasminogen activator（t PA）and plasminogen activator inhibitor-1（PAI-1）,which is thought to play an important role in nerve ***：Thirty-two adult male Sprague-Dawley rats were subjected to sciatic nerve crush injury and 16 rats（sham-operated group）went through a sham *** group was given no treatment while tuina group received tuina therapy since day 7 *** treatment was performed once a day and lasted for 20 *** sciatic functional index was examined every 5days during the treatment *** rats＇gastrocnemius muscles were evaluated for changes in mass and immunohistochemistry techniques were performed to detect the levels of tP A and ***：Tuina therapy improved the motor function of sciatic nerve injured rats（P〈0.05）,however,it did not increase muscle volume（P〈0.05）.Tuina downregulated the levels of t PA and PAI-1（P〈0.05）.Conclusions：The present study implies that tuina treatment could accelerate rehabilitation of peripheral nerve injury.

关键词： Chinese medicine physical therapy peripheral neuropathy massage

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High expression level of EDIL3 in HCC predicts poor prognosis of HCC patients

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World Journal of Gastroenterology 2010年第36期16卷 4611-4615页

作者： jian-cong Sun,Xiao-Ting Liang,Ke Pan,Hui Wang,Jing-Jing Zhao,jian-Jun Li,Hai-Qing Ma,Yi-Bing Chen,jian-Chuan Xia,State Key Laboratory of Oncology in South China,Cancer Center,Sun Yat-Sen University,Guangzhou 510060,Guangdong Province,China State Key Laboratory of Oncology in Southern China Cancer Center Sun Yat-Sen University Guangzhou 510060 Guangdong Province China.

AIM:To determine the role of epidermal growth factor-like repeats and discoidin I-like domains 3(EDIL3)in pathogenesis of hepatocellular carcinoma(HCC)by investigating the EDIL3 expression in HCC and its prognostic value for ***:EDIL3 expression was detected in 101 HCC surgical tissue samples with immunohistochemistry method,and its relation with clinicopathologic features and prognosis of HCC patients was ***:EDIL3 was highly expressed in 48.5%of the HCC *** the EDIL3 expression level did not correlate with any clinicopathological parameters,KaplanMeier survival analysis showed that high expression level of EDIL3 resulted in a significantly poor prognosis of HCC patients(log-rank test,P=0.010).Multivariate Cox's analysis showed that the EDIL3 expression level was a significant and independent prognostic parameter for the overall survival rate of HCC patients(hazard ratio=1.978,95%confidence interval =1.139-3.435,P=0.015).CONCLUSION:High expression level of EDIL3 pre-dicts poor prognosis of HCC ***3 may be a potential target of antiangiogenic therapy for HCC.

关键词： Epidermal growth factor-like repeats and discoidin I-like domains 3 Hepatocellular carcinoma Prognosis Angiogenesis

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权利的防御权能与立法机关的消极义务

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内蒙古社会科学 2008年第5期29卷 12-17页

作者：菅从进徐州师范大学法政学院江苏徐州221116

权利的防御权能是指权利主体应享有的一种要求其他人承担不得侵害其权利的不作为义务的能力。在一个真正实行宪政和法治的国家,基本权利的防御权能,应首先是针对国家立法机关的。从基本权利的防御权能充分化的角度,可对国家立法机关应... 详细信息

权利的防御权能是指权利主体应享有的一种要求其他人承担不得侵害其权利的不作为义务的能力。在一个真正实行宪政和法治的国家,基本权利的防御权能,应首先是针对国家立法机关的。从基本权利的防御权能充分化的角度,可对国家立法机关应承担的相应消极义务进行系统的条理化定位和分析,并可准确认知我国宪法在确认基本权利针对立法权力的防御权能方面存在明显的不足。

关键词：权利防御权能立法机关消极义务

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Investigation of transport properties of perovskite single crystals by pulsed and DC bias transient current technique

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Chinese Physics B 2022年第11期31卷 465-469页

作者： Juan Qin Gang Cao Run Xu Jing Lin Hua Meng Wen-Zhen Wang Zi-Ye Hong jian-cong Cai Dong-Mei Li School of Materials Science and Engineering Shanghai UniversityShanghai 200444China Zhejiang Institute of Advanced Materials Shanghai UniversityJiashan 314113China

Time-of-flight(ToF)transient current method is an important technique to study the transport characteristics of ***,both the direct current(DC)and pulsed bias ToF transient current method are employed to investigate the transport properties and electric field distribution inside the MAPbI_(3) single crystal *** to the almost homogeneous electric field built inside the detector during pulsed bias ToF measurement,the free hole mobility can be directly calculated to be about 22 cm^(2)·V^(-1)·s^(-1),and the hole lifetime is around 6.5μs–17.5μ***,the mobility-lifetime product can be derived to be 1.4×10^(-4)cm^(2)·V^(-1)–3.9×10^(-4)cm^(2)·V^(-1).The transit time measured under the DC bias deviates with increasing voltage compared with that under the pulsed bias,which arises mainly from the inhomogeneous electric field distribution inside the *** positive space charge density can then be deduced to increase from 3.1×10^(10)cm^(-3)to 6.89×10^(10)cm^(-3)in a bias range of 50 V–150 *** ToF measurement can provide us with a facile way to accurately measure the transport properties of the perovskite single crystals,and is also helpful in obtaining a rough picture of the internal electric field distribution.

关键词： MAPbI3 space charge density electric field distribution time-of-flight measurement

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基于ABAQUS的三维边坡降雨入渗模块的开发及其应用

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岩土工程学报 2015年第4期37卷 667-674页

作者：李宁许建聪上海理工大学环境与建筑学院上海200093 同济大学地下建筑与工程系上海200092

为了克服ABAQUS在进行降雨入渗模拟方面的局限性,采用Python语言对ABAQUS软件的降雨入渗边界进行二次开发,将降雨边界作为不定边界,采用迭代算法对降雨入渗边界进行处理,开发出基于ABAQUS软件的降雨入渗模块。该模块克服了ABAQUS软件中... 详细信息

为了克服ABAQUS在进行降雨入渗模拟方面的局限性,采用Python语言对ABAQUS软件的降雨入渗边界进行二次开发,将降雨边界作为不定边界,采用迭代算法对降雨入渗边界进行处理,开发出基于ABAQUS软件的降雨入渗模块。该模块克服了ABAQUS软件中只能模拟降雨全部入渗,入渗率保持不变的单一情况,完善了ABAQUS软件的降雨入渗分析功能。通过与土柱入渗试验进行比较,证明开发出的降雨入渗模块是稳定可靠的。在此基础上,采用该模块研究了抗滑桩边坡的降雨入渗过程,结果表明:抗滑桩虽然可以有效的提高边坡的稳定性,但是,在降雨条件下,抗滑桩的存在减小了排水有效断面,使坡体后缘汇集而来的地下水得不到及时排泄,这又会对边坡稳定性产生不利影响。因此在多雨地区进行抗滑桩设计应充分考虑降雨所带来的不利影响,综合评价抗滑桩的加固效果。借助于ABAQUS的强大功能,该模块可以为以后进行更复杂的降雨相关问题的研究提供一个良好的研究平台。

关键词：抗滑桩边坡饱和–非饱和渗流降雨入渗 ABAQUS

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