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Journal of Clinical and Nursing Research 2024年第6期8卷 123-128页

作者： Han Zou Yuting Song jiaju ma Hebu Qian Yueping Yao Suzhou Ninth People's Hospital Suzhou 215200Jiangsu ProvinceChina

Objective:To analyze the therapeutic effect of Xuebijing+antimicrobials in intensive care unit(ICU)patients with severe ***:60 ICU patients with severe pneumonia from June 2021 to June 2023 were selected and divided by the random number table method,with 30 cases in each *** observation group received Xuebijing+antimicrobial treatment,while the control group received only antimicrobial *** differences in rehabilitation indexes,test indexes,and inflammation indexes were compared between the two ***:Mechanical ventilation time,fever reduction time,cough relief time,and hospitalization time of the observation group were significantly shorter than those of the control group(Pmation,enhance immune function,shorten the pneumonia recovery time,and reduce the adverse reactions of severe pneumonia.

关键词： Intensive care unit severe pneumonia Antimicrobials Xuebijing Efficacy

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从《温疫论》探讨吴又可治疗疫病的临床思维

中医学报 2024年第1期39卷 39-43页

作者：马家驹首都医科大学附属北京中医医院北京100010

吴又可借助于膜原提出温疫初起,不同于伤寒表证,提出治法为达原饮促邪溃败。邪客膜原(达原饮证)本质是中焦的湿遏热伏重症,舌诊可见舌质暗红或舌质紫绛,以舌上苔白厚腻如积粉为标志性症状。吴又可治疗疫病,第一步是用辛温燥烈的达原饮... 详细信息

吴又可借助于膜原提出温疫初起,不同于伤寒表证,提出治法为达原饮促邪溃败。邪客膜原(达原饮证)本质是中焦的湿遏热伏重症,舌诊可见舌质暗红或舌质紫绛,以舌上苔白厚腻如积粉为标志性症状。吴又可治疗疫病,第一步是用辛温燥烈的达原饮、三消饮疏利气机,促邪溃败,将湿遏热伏传变为单纯的热证,目的只是治疗疫病初起的邪客膜原证,并非治疗疫病的主方。三消饮较达原饮,更能体现吴又可的临床思维。第二步是依据邪气溃败后的传变选择相应的治法,里传入胃用大承气汤攻下,表传用白虎汤清解里热,才是治疗的重点。因此吴又可认为治法全在后段功夫,始终着眼于促邪溃败和逐邪外出。吴又可治疗疫病的临床思维对治疗中焦湿遏热伏证具有较强的临床指导价值。

关键词：疫病邪客膜原证中焦湿遏热伏证达原饮三消饮大承气汤白虎汤吴又可《温疫论》

Mixture prepared with Chinese medicines in terms of releasing exterior cold and clearing interior heat: its efficacy and safety in patients with seasonal influenza-a randomized controlled trial

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Journal of Traditional Chinese Medicine 2018年第5期38卷 746-753页

作者： Wu Zhisong Li Guodong Wei Wan Liu Zhaoheng Wang Wei ma Ruihong Liu Wenhong ma jiaju Wang Yuguang Jiao Yang Department of Intensive care unit Dongfang Hospital Affiliated to Beijing University of Chinese Medicine Graduate School Beijing University of Chinese Medicine Department of Chinese Medicine Concord Hospital Affiliated to Fujian Medical University Department of Respiratory medicine Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University Department of Internal Medicine Dongfang Hospital Affiliated to Beijing University of Chinese Medicine

OBJECTIVE: To assess the efficacy and safety in 105 patients with seasonal Influenza in Beijing, the mixture prepared with Chinese medicines follows the treatment regimen of releasing exterior cold andclearing interior ***: Total 330 patients with seasonal influenza were enrolled and randomly and averagely divided into the Chinese herbal medicine, the western medicine and the Chinese patent medicine group. They were treated with Chinese medicine Oseltamivir Phosphate Capsules and the Scattering Wind and Resolving Toxins Capsules. The main efficacy indicators were the antifebrile onset time and recovery time of body temperature. The efficacy and safety of the mixture was scientifically evaluated. Comparisons of several variables were ***: Median antifebrile onset time of the Chinese herbal medicine group was significantly shorter than the western medicine group(P main symptoms and some minor symptom patterns of the Chinese herbal medicine group were higher than the other 2 ***: The mixture of releasing exterior cold and clearing interior heat could significantly shorten the fever time with safety.

关键词： Releasing exterior cold and clearing interior heat Influenza efficacy Mixture prepared with Chinese medicines

ELASTOHYDRODYNAMIC LUBRICATION OF LOGARITHMIC PROFILE ROLLER CONTACTS

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Chinese Journal of Mechanical Engineering 2001年第4期14卷 347-352页

作者： Chen Xiaoyang, Shen Xuejin (Research Institute of Bearings,Shanghai University) Xu Wen, ma jiaju (Zhejiang University) 上海大学上海浙江大学浙江

An account of numerical solutions to the isothermal and flooded elastohydrodynamic lubrication(EHL)of a logarithmic profile roller,which is rolling over a flat plane,is given The analysis takes account of sideways flow of lubricant in the inlet region of the contact When the results are presented in suitable non dimensional groups,it is shown that more uniformly pressure and shape of the film distributing in axial direction is taken place under light loading As the increase of the load,the end closure is displayed and the oil pressure rises sharply at the ends The seal action formed by the end closure makes the film thickness a little And the minimum film thickness is transferred from the central to the ends and the value is reduced rapidly As the increase of the speed,the end closure becomes much serious The optimum crowning value obtained in EHL state is larger than the design value obtained in elastostatic contact state for the same working conditions In order to verify the correctness of theory,optical interferometry is applied to measure the oil film thickness between a logarithmic profiled roller and a glass plate under pure rolling conditions It is found the agreement between numerical solutions and experiments is very good.

关键词： Elastohydrodynamic lubrication(EHL) Logarithmic profile roller Finite line contacts Optical interferom etry measurement

血清LncRNA-maLAT1、Ang-2与重症急性胰腺炎患者并发急性胃肠损伤的相关性研究

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疑难病杂志 2024年第10期23卷 1221-1226页

作者：马家驹邹晗晏倩李玉卓浦秦华苏州大学附属苏州市第九人民医院重症医学科江苏苏州215200

目的探讨血清长链非编码RNA-肺腺癌转移相关转录本1(LncRNA-maLAT1)、血管生成素-2(Ang-2)与重症急性胰腺炎(SAP)患者并发急性胃肠损伤(AGI)的相关性。方法选取2021年1月—2023年1月苏州大学附属苏州市第九人民医院重症医学科收治的轻... 详细信息

目的探讨血清长链非编码RNA-肺腺癌转移相关转录本1(LncRNA-maLAT1)、血管生成素-2(Ang-2)与重症急性胰腺炎(SAP)患者并发急性胃肠损伤(AGI)的相关性。方法选取2021年1月—2023年1月苏州大学附属苏州市第九人民医院重症医学科收治的轻症急性胰腺炎(AP)患者78例为轻症AP组、中度AP患者78例为中度AP组、SAP患者145例为SAP组,根据是否并发AGI将SAP患者分为AGI亚组83例和非AGI亚组62例。采用实时荧光定量PCR检测血清LncRNA-maLAT1水平,酶联免疫吸附法检测血清Ang-2水平;多因素Logistic回归分析SAP患者并发AGI的影响因素;受试者工作特征(ROC)曲线评价血清LncRNA-maLAT1、Ang-2水平对SAP患者并发AGI的预测价值。结果轻症AP组、中度AP组、SAP组血清LncRNA-maLAT1、Ang-2水平依次升高(F/P=659.197/maLAT1、Ang-2水平高于非AGI亚组(χ^(2)/t/P=19.273/maLAT1高、Ang-2高为SAP患者并发AGI的独立危险因素[OR(95%CI)=4.496(1.335~15.138)、1.331(1.142~1.551)、1.070(1.020~1.123)、1.101(1.055~1.148)、1.571(1.239~1.994)];血清LncRNA-maLAT1、Ang-2水平及二者联合预测SAP患者并发AGI的AUC分别为0.790、0.785、0.895,二者联合的AUC大于血清LncRNA-maLAT1、Ang-2水平单独预测(Z/P=3.143/0.002、3.650/maLAT1、Ang-2水平升高与SAP患者并发AGI独立相关,血清LncRNA-maLAT1联合Ang-2水平预测SAP患者并发AGI的价值较高。

关键词：重症急性胰腺炎长链非编码RNA-肺腺癌转移相关转录本1 血管生成素-2 急性胃肠损伤

Association between gastrointestinal heat retention syndrome and respiratory tract infections in children:A prospective cohort study

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Journal of Traditional Chinese Medical Sciences 2021年第3期8卷 216-223页

作者： Fei Dong He Yu Liqun Wu Tiegang Liu Xueyan ma jiaju ma Xiaohong Gu School of Chinese Medicine Beijing University of Chinese MedicineBeijing102488China Pediatric Department Dongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijing100078China Pneumology Department Beijing Hospital of Traditional Chinese MedicineBeijing100010China

Objective:To explore the relationship between gastrointestinal heat retention syndrome and the incidence of pneumonia and recurrent respiratory tract infections(RRTIs)in ***:A prospective cohort study was conducted in the pediatric outpatient department of Beijing Dongfang *** without respiratory tract infections(RTIs)were consecutively recruited according to the selection criteria.A semi-structured questionnaire was used to record traditional Chinese medicine(TCM)symptoms and demographic and physiological *** heat retention syndrome was considered to be a predisposing factor and was diagnosed according to a scale with reliability and *** participants were followed up for 12 *** and their parents or guardians were contacted via clinical interviews and telephone every 6 *** of pneumonia and RTIs were recorded in ***:A total of 420 children were *** participants,370(88.10%)were followed up for 12 *** mean number of RTI episodes per participant was 5.37(95%CI:5.14 to 5.60).In total,186 participants in the gastrointestinal heat retention syndrome group and 184 participants in the nongastrointestinal heat retention syndrome group completed the 12-month follow-up *** baseline of both groups was *** incidence of RRTIs in children with gastrointestinal heat retention syndrome was 1.27(95%CI:1.01 to 1.59)times that in children without gastrointestinal heat retention *** regression analysis revealed that abnormally increased appetite with frequent hunger,foul breath,dry stools,and dark red or purple fingerprints were positively correlated with the incidence of *** and feverish feelings in the palms and soles were positively correlated with the occurrence of ***:Gastrointestinal heat retention syndrome is a risk factor for RRTIs in *** with larger sample sizes and longer follow-up tim

关键词： Gastrointestinal heat retention syndrome Pneumonia Recurrent respiratory tract infections Children Prospective cohort study

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埋入式进气道设计

推进技术 1998年第4期19卷 36-40页

作者：彭成一马强马家驹南京航空航天大学动力工程系

提出了将埋入式进气道分为导流段与管道两部分的设计方案，并对此进气道进行了低速Ｍａ＝０．３７和高速Ｍａ＝０．７０的风洞试验，结果表明：新的设计方案能提高埋入式进气道的性能，使其σ≥０．９４，Δσ＜０．０１。

关键词：飞机埋入式进气道总压恢复系数设计

Association between dietary habits and recurrent respiratory infection in children: A case-control study

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Journal of Traditional Chinese Medical Sciences 2015年第2期2卷 105-110页

作者： Wang Zhang He Yu Jinbang Shang Tiegang Liu jiaju ma Xiaohong Gu School of Basic Medical Science Beijing University of Chinese MedicineBeijing 100029China Beijing Drum Tower Hospital of Traditional Chinese Medicine Beijing 100009China Dongzhimen Hospital Beijing University of Chinese MedicineBeijing 101121China Beijing Hospital of Chinese Medicine Beijing 100010China

Objective:To explore the association between dietary habits and recurrent respiratory infection(RRI)in children aged 0e14 ***:This caseecontrol study compared dietary data of children with(cases)and without RRI(controls)collected via structured *** were recruited from Chinese medicine clinics,hospitals,and children’s learning institutions in Beijing.A logistic regression analysis and odds ratio(OR)calculations were conducted using SPSS 17.0 ***:A total of 241 questionnaires were collected(case:control ratio:approximately 2:1).Frequent consumption of processed foods(OR Z 2.988,95%confidence intervals 1.375e6.491)and high-sugar foods(OR Z 2.268,95%confidence intervals 1.163e4.424),frequent picky eating(OR Z 2.614,95%confidence intervals 1.363e5.014),and a meat-heavy diet with fewer vegetables(OR Z 1.830,95%confidence intervals 1.358e2.467)correlated positively correlated with ***,57.80%of the children with RRI were addicted to high-sugar foods,compared with 41.57%of the children without RRI(P Z.015).Furthermore,63.16%of the children with RRI were picky eaters,compared with 48.31%of the children without RRI(P Z.024).Finally,30.92%of the children with RRI frequently consumed processed foods,compared with only 17.98%of the children without RRI(P Z.027Conclusion:Although RRI correlates positively with several dietary habits,in the future,prospective cohort studies with larger samples are needed to generalize these findings.

关键词： Caseecontrol study Recurrent respiratory infection Dietary habits

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ABS透明塑料低表面能基材粘接优化设计

塑料 2019年第3期48卷 23-25,41页

作者：孙会宁马家举绵阳职业技术学院材料工程系四川绵阳621000 安徽理工大学化学工程学院安徽淮南232001

介绍了 ABS 透明塑料基材的特性,测试出 ABS 透明塑料基材的表面能,针对 ABS 基材表面特性,分析了粘接过程中使用市售双组份胶黏剂粘接出现的问题,阐述了紫外光固化胶黏剂的优点,从 ABS 基材粘接用胶黏剂的选型、配方的研制、基材表面... 详细信息

介绍了 ABS 透明塑料基材的特性,测试出 ABS 透明塑料基材的表面能,针对 ABS 基材表面特性,分析了粘接过程中使用市售双组份胶黏剂粘接出现的问题,阐述了紫外光固化胶黏剂的优点,从 ABS 基材粘接用胶黏剂的选型、配方的研制、基材表面处理、涂布与粘接工艺、固化等方面进行优化设计。实验证明:采用自制的、无需配制的、直接使用的紫外光和热双重固化的胶黏剂,且预聚物和稀释剂配比保持在 52∶ 43,光引发剂含量为 3%,热引发剂含量为1. 5%,其表面能比市售胶黏剂降低了 11 mN/m,其粘接强度最佳,通过基材处理、改善粘接工艺,完善固化条件,克服氧阻聚,提高固化度等,使 ABS 透明塑料基材粘接强度达到 18 MPa 以上。

关键词： ABS 塑料基材粘接光固化低表面能

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膜原及达原饮的临床指征探析

北京中医药大学学报 2020年第6期43卷 463-468页

作者：马家驹王玉光首都医科大学附属北京中医医院北京100010

膜原是疫疠发病的重要部位,达原饮是治疗温疫邪客膜原的代表方,但因其辛温燥烈影响了本方的临床应用。本文从《温疫论》原文出发,结合后世医家的认识,提出膜原及达原饮方证的本质为中焦的湿遏热伏重证,因疫病发病急,传染性强,病死率高,... 详细信息

膜原是疫疠发病的重要部位,达原饮是治疗温疫邪客膜原的代表方,但因其辛温燥烈影响了本方的临床应用。本文从《温疫论》原文出发,结合后世医家的认识,提出膜原及达原饮方证的本质为中焦的湿遏热伏重证,因疫病发病急,传染性强,病死率高,首重祛邪,用达原饮辛温燥烈,疏利膜原,促进湿热证传变为单纯热证,即吴又可促邪溃败之意,符合分消走泄的湿热治疗原则。同时也提出温疫治疗始终要围绕邪气论治,并凝练归纳了达原饮证的应用指征,探讨了本次新型冠状病毒肺炎中膜原及达原饮的理论价值。

关键词：膜原达原饮吴又可温疫论湿遏热伏新型冠状病毒肺炎