Association between gastrointestinal heat retention syndrome and respiratory tract infections in children:A prospective cohort study

作     者：Fei Dong He Yu Liqun Wu Tiegang Liu Xueyan Ma Jiaju Ma Xiaohong Gu Fei Dong;He Yu;Liqun Wu;Tiegang Liu;Xueyan Ma;Jiaju Ma;Xiaohong Gu

作者机构：School of Chinese MedicineBeijing University of Chinese MedicineBeijing102488China Pediatric DepartmentDongfang Hospital Affiliated to Beijing University of Chinese MedicineBeijing100078China Pneumology DepartmentBeijing Hospital of Traditional Chinese MedicineBeijing100010China 

出 版 物：《Journal of Traditional Chinese Medical Sciences》 (中医科学杂志（英文）)

年 卷 期：2021年第8卷第3期

页      面：216-223页

学科分类：1005[医学-中医学] 100510[医学-中医儿科学] 10[医学] 

基　　金：funded by the National Natural Science Foundation of China(81373769) Beijing Educational Committee cooperation projects(1000062520115) National Key R&D Program of China(2018YFC1704101)granted to Prof.Xiaohong Gu funded by China Postdoctoral Science Foundation(2020T130009ZX) 

主　　题：Gastrointestinal heat retention syndrome Pneumonia Recurrent respiratory tract infections Children Prospective cohort study 

摘      要：Objective:To explore the relationship between gastrointestinal heat retention syndrome and the incidence of pneumonia and recurrent respiratory tract infections(RRTIs)in ***:A prospective cohort study was conducted in the pediatric outpatient department of Beijing Dongfang *** without respiratory tract infections(RTIs)were consecutively recruited according to the selection criteria.A semi-structured questionnaire was used to record traditional Chinese medicine(TCM)symptoms and demographic and physiological *** heat retention syndrome was considered to be a predisposing factor and was diagnosed according to a scale with reliability and *** participants were followed up for 12 *** and their parents or guardians were contacted via clinical interviews and telephone every 6 *** of pneumonia and RTIs were recorded in ***:A total of 420 children were *** participants,370(88.10%)were followed up for 12 *** mean number of RTI episodes per participant was 5.37(95%CI:5.14 to 5.60).In total,186 participants in the gastrointestinal heat retention syndrome group and 184 participants in the nongastrointestinal heat retention syndrome group completed the 12-month follow-up *** baseline of both groups was *** incidence of RRTIs in children with gastrointestinal heat retention syndrome was 1.27(95%CI:1.01 to 1.59)times that in children without gastrointestinal heat retention *** regression analysis revealed that abnormally increased appetite with frequent hunger,foul breath,dry stools,and dark red or purple fingerprints were positively correlated with the incidence of *** and feverish feelings in the palms and soles were positively correlated with the occurrence of ***:Gastrointestinal heat retention syndrome is a risk factor for RRTIs in *** with larger sample sizes and longer follow-up tim