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Experimental demonstration of coherent photonic neural computing based on a Fabry–Perot laser with a saturable absorber

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Photonics Research 2023年第1期11卷 65-71页

作者： DIANZHUANG ZHENG SHUIYING XIANG XINGXING GUO YAHUI ZHANG BILING GU HONGJI WANG ZHENZHEN XU XIAOJUN ZHU yueCHUN shi yue HAO State Key Laboratory of Integrated Service Networks Xidian UniversityXi'an 710071China State Key Discipline Laboratory of Wide Band Gap Semiconductor Technology School of MicroelectronicsXidian UniversityXi'an 710071China Key Laboratory of Intelligent Optical Sensing and Manipulation Ministry of EducationNational Laboratory of Solid State MicrostructuresCollege of Engineering and Applied SciencesInstitute of Optical Communication EngineeringNanjing UniversityNanjing 210023China School of Information Science and Technology Nantong UniversityNantong 226019China Yongjiang Laboratory Ningbo 315202China

As Moore’s law has reached its limits,it is becoming increasingly difficult for traditional computing architectures to meet the demands of continued growth in computing *** neural computing has become a promising approach to overcome the von Neuman ***,while photonic neural networks are good at linear computing,it is difficult to achieve nonlinear ***,we propose and experimentally demonstrate a coherent photonic spiking neural network consisting of Mach–Zehnder modulators(MZMs)as the synapse and an integrated quantum-well Fabry–Perot laser with a saturable absorber(FP-SA)as the photonic spiking *** linear computation and nonlinear computation are realized in the *** such a coherent architecture,two presynaptic signals are modulated and weighted with two intensity modulation MZMs through the same optical *** nonlinear neuron-like dynamics including temporal integration,threshold,and refractory period are successfully ***,the effects of frequency detuning on the nonlinear neuron-like dynamics are also explored,and the frequency detuning condition is *** proposed hardware architecture plays a foundational role in constructing a large-scale coherent photonic spiking neural network.

关键词： tuning laser neural

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Integrated System for Combined Optical Coherence Tomography-Raman Spectroscopy of Neocaridina denticulate sinensis

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Journal of Ocean University of China 2021年第1期20卷 94-100页

作者： LIU Xiaoying ZHANG Xu MA Jun shi Xiaofeng Optics and Optoelectronics Laboratory Ocean University of ChinaQingdao 266100China

Optical coherence tomography(OCT)and Raman spectroscopy(RS)can be complementary biological tissue optical analysis *** study the internal structure and tissue compositions of biological samples,an OCT-RS system was built to carry out OCT section imaging and RS analysis in *** denticulate sinensis were collected regularly for morphological observation by OCT imaging and biochemical investigation based on the Raman *** internal structure of the *** sinensis was imaged by OCT,and the morphology of the tissues and the position in the body were distinguished according to the gray scale *** imaging depth along the vertical direction of Z-axis in *** sinensis is about 1.60 *** detection was selectively performed based on the OCT *** main Raman peaks of the rostrum,the cephalothorax,the abdominal segment,and the telson section are at 1006,1156,1447,1491 and 1515 cm-1,which are identified as proteins and amino *** presence of 1497 cm-1 at the cephalothorax is different from other parts,probably due to the presence of organs such as ovary,whose compositions are different from those of other *** combination of optical coherence tomography and Raman spectroscopy can provide information about morphological and biochemical features of tissues,and has potential applications in biomedical detection and imaging.

关键词： optical coherence tomography(OCT) Raman spectroscopy(RS) Neocaridina denticulate sinensis biological tissue

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Ligand-Controlled Palladium-Catalyzed Regiodivergent Defluorinative Allylation of gem-Difluorocyclopropanes viaσ-Bond Activation

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Chinese Journal of Chemistry 2022年第19期40卷 2345-2355页

作者： Lei Wu Minyan Wang Yong Liang Zhuangzhi shi State Key Laboratory of Coordination Chemistry School of Chemistry and Chemical EngineeringNanjing UniversityNanjingJiangsu210093 China School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiangHenan453007 China

Monofluoroalkenes are important and versatile privileged components in pharmacologically relevant ***,we report a method for the selective construction of these compounds in a diversity-oriented fashion through regiodivergent cross-coupling of gem-difluorocyclopropanes with allylboronates by employing a palladium catalyst with two different ligands,in which gem-difluorocyclopropanes were used as allyl electrophiles by C—C and C—F bond *** the presence of 2-biphenylyl(diphenyl)phosphine as ligand,the linear-selective allyl–allyl bond formation is highly obtained,while utilizing the sterically hindered BrettPhos(dicyclohexyl[3,6-dimethoxy-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine)as the ligand favors the generation of the branched-selective *** and computational studies investigated the key steps of the cross-coupling reactions,revealing the origin of the ligand-controlled regiodivergence.

关键词： Allylation C-C activation Cross-coupling gem-Difluorocyclopropanes Defluorination

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B-样条曲线的节点去除与光顺

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软件学报 2001年第1期12卷 143-147页

作者：满家巨胡事民雍俊海孙家广清华大学国家CAD工程中心

研究了 B-样条曲线节点的去除问题 ,简化了 B-样条曲线内部节点精确去除的充要条件 .基于约束优化方法 ,通过扰动 B-样条曲线的控制顶点 ,给出了节点去除的一个新算法 ,并用于光顺 B-样条曲线 .

关键词： B-样条曲线节点插入光顺约束优化计算机辅助设计

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Maternal stevioside supplementation improves intestinal immune function of chicken offspring potentially via modulating gut microbiota and down-regulating the promoter methylation level of suppressor of cytokine signaling 1(SOCS1)

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Animal Nutrition 2022年第3期10卷 329-346页

作者： Jingle jiang Lina Qi Quanwei Wei Fangxiong shi College of Animal Science and Technology Nanjing Agricultural UniversityNanjing 210095China

The intestinal immune function of chickens is limited during the early growing *** nutritional intervention has been suggested to affect the innate immunity of *** present study aimed to investigate the effects of maternal stevioside supplementation on the intestinal immune function of chicken offspring.A total of 120 Jinmao yellow-feathered breeder hens were fed a basal diet or a diet supplemented with 250 mg/kg stevioside for 5 *** the last week,200 breeding eggs from each group were collected for *** hatching,80 male offspring(40 chickens from each group)were randomly selected and fed the same basal diet for 28 *** addition,90 well-shaped fertile eggs of non-treated breeder hens were incubated for the in ovo injection *** dissolved in 20%glycerol was injected at 7 d of *** results showed that maternal stevioside supplementation could improve embryonic development,jejunal integrity and proliferation in the jejunal crypt(P0.05).Furthermore,maternal stevioside supplementation could induce hypo-methylation on the promoter region of suppressor of cytokine signaling 1(SOCS1).In conclusion,maternal stevioside supplementation could improve the intestinal immune function of chicken offspring potentially via modulating the gut microbiota and downregulating the promoter meth

关键词： Maternal Stevioside Jejunum Transcriptome Offspring Immune function

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Service-Driven Coded Forward Scheme Based on Streaming Transmission Model for Lunar Space Communication Networks

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China Communications 2020年第7期17卷 15-26页

作者： Shushi Gu Ye Wang Guoqing Chen Shuo shi School of Electronic and Information Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China Peng Cheng Laboratory Shenzhen 518055China School of Electronic and Information Engineering Harbin Institute of TechnologyHarbin 150001China

With the rapid development of lunar exploration,a large amount of scientific data and media stream service needs to be transmitted through Lunar Space Communication Networks(LSCNs).Due to limited transmitter power and intermittent,long delay and packet loss connections,the reliable and efficient multi-priority services’transmission in LSCNs becomes an urgent ***,we propose a Streaming Transmission Model(STM)based on temporal and spatial topology graph to describe the delay and energy consumption for data transmission in ***,we further devise a Coded Forward Scheme based on STM,termed CFS-STM,to achieve multi-priority service in two steps:i).Link Stability Function(LSF)is established by solving an optimization problem to choose the appropriate single-hop ***).Raptor code is employed to further save delay and energy with adjustable code-rate according to the different channel *** results show that,CFS-STM can significantly improve the transmission efficiency of multi-service priority streaming delivery in LSCNs.

关键词： Streaming service delay

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Visible light-driven photocatalysis of W,N co-doped TiO_2

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Particuology 2013年第6期11卷 732-736页

作者： Xue Li Yunyi Liu Pengfei Yang Yongchao shi College of Chemical Engineering Shenyang University of Chemical Technology

W, N co-doped TiO2 nanoparticles were synthesized by a sol-gel method. The prepared samples were characterized by X-ray diffraction （XRD）, field emission scanning electron microscopy （FE-SEM）, trans- mission electron microscopy （TEM）, Fourier transform infrared spectroscopy （FT-1R）, X-ray photoelectron spectroscopy （XPS） and diffuse reflectance spectrophotometry （DRS）. The results showed that the co- doped photocatalysts were essentially uniform spherical particles with the smallest particle size of 22.5 nm. Compared to un-doped TiO2, N-TiO2 and P-25, the absorption edge of the W, N co-doped TiO2 shifted to longer wavelength and its photocatalytic activity for degradation of methyl orange （MO） under Xe-lamp （350W） was higher.

关键词： TiO2 Co-doped Visible light Pbotocatalytic activity

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Molecular Simulation of Methane Adsorption in Different Micro Porous Activated Carbons at Different Temperatures

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Journal of Wuhan University of Technology(Materials Science) 2023年第1期38卷 1-11页

作者： Rugarabamu John Rwiza 赵东风 SONG Kunli LI shi College of Chemical Engineering China University of Petroleum(East China)Qingdao 266580China College of Earth Sciences and Engineering The University of DodomaDodomaTanzania

We employed the previously developed micro porous activated carbon models of different pore sizes ranges of 9-11?,10-12?,and 13-16?that were constructed by molecular simulation method based on a random packing of platelets of carbon sheets,functionalized with oxygen containing groups,to study the adsorption behavior of methane *** studying methane adsorption behavior,we used Grand Canonical Monte Carlo and Molecular Dynamics methods at different temperatures of 273.15,298.15 and303.15 *** isotherms,isosteric heats of adsorption,adsorption energy distributions and porosity changes of the models during adsorption process were analyzed and ***,radial distribution Functions,relative distribution and diffusion coefficients of methane molecules in activated carbon models at different temperatures were *** the analysis,the main results indicated that large micro pores activated carbons were favorable for storing methane at lower temperatures and small micro pores were the most favorable for adsorbing methane molecules at higher ***,the developed model structures showed high capacities to store methane molecule at ambient temperatures and low pressure.

关键词： Molecular simulation activated carbon methane adsorption MD GCMC

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A Multi-Agent Immune Network Algorithm and Its Application to Murphree Efficiency Determination for the Distillation Column

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Journal of Bionic Engineering 2011年第2期8卷 181-190页

作者： Xuhua shi Feng Qian State Key Laboratory qf Chemical Engineering East China University of Science and Technology Shanghai 200237 P. R. China College of Information Science and Engineering Ningbo University Ningbo 315211 P. R. China

Artificial Immune Network （aiNet） algorithms have become popular for global optimization in many modem industrial applications. However, high-dimensional systems using such models suffer from a potential premature convergence problem. In the existing aiNet algorithms, the premature convergence problem can be avoided by implementing various clonal selection methods, such as immune suppression and mutation approaches, both for single population and multi-population cases. This paper presents a new Multi-Agent Artificial Immune Network （Ma-aiNet） algorithm, which combines immune mechanics and multiagent technology, to overcome the premature convergence problem in high-dimensional systems and to efficiently use the agent ability of sensing and acting on the environment. Ma-aiNet integrates global and local search algorithms. The perform- ance of the proposed method is evaluated using 10 benchmark problems, and the results are compared with other well-known intelligent algorithms. The study demonstrates that Ma-aiNet outperforms other algorithms tested. Ma-aiNet is also used to determine the Murphree efficiency of a distillation column with satisfactory results.

关键词： bio-inspired optimization multi-agent immune network distillation column Murphree efficiency

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Novel agents targeting leukemia cells and immune microenvironment for prevention and treatment of relapse of acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation

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Acta Pharmaceutica Sinica B 2020年第11期10卷 2125-2139页

作者： Wei shi Weiwei Jin Linghui Xia Yu Hu Institute of Hematology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Fred Hutchinson Cancer Research Center SeattleWA 98109-1024USA Department of Cardiovascular Optical Valley School DistrictHubei Provincial Hospital of Traditional Chinese MedicineWuhan 430061China Hubei Province Academy of Traditional Chinese Medicine Wuhan 430074China

Relapse remains the worst life-threatening complications after allogeneic hematopoietic stem cell transplantation(allo-HSCT)in patients with acute myeloid leukemia(AML),whose prognosis has been historically *** the rapid development of genomics and immunotherapies,the interference strategies for AML recurrence have been changing these *** and more novel targeting agents that have received the *** and Drug Administration(FDA)approval for de novo AML treatment have been administrated in the salvage or maintenance therapy of post-HSCT *** strategies that regulate the immune microenvironment of and optimize the graft versus leukemia(GVL)effect of immune cells are gradually *** agents not only have been proven to achieve clinical benefits from a single drug,but if combined with classic therapies,can significantly improve the poor prognosis of AML patients who relapse after *** review will focus on currently available and promising upcoming agents and also discuss the challenges and limitations of targeted therapies in the allogeneic hematopoietic stem cell transplantation community.

关键词： AML Targeted therapy Relapse Immune microenvironment Allogeneic hematopoietic stem cell transplantation Oncogenic effectors Metabolism Surface markers

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