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Meta-analysis on the epidemiology of gastroesophageal reflux disease in China

World Journal of Gastroenterology 2022年第45期28卷 6410-6420页

作者： Tai-Liang Lu Shao-Rong Li jia-min zhang Chao-Wu Chen Department of Gastrointestinal Surgery Hunan Provincial People's HospitalThe First Affiliated Hospital of Hunan Normal UniversityChangsha 410005Hunan ProvinceChina Operating Room Sun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120Guangdong ProvinceChina

BACKGROUND No large-scale epidemiological survey on the prevalence of gastroesophageal reflux disease(GERD)in China has been *** has a large population and a complex geographical *** is important to understand the prevalence and spatial distribution of GERD in *** To explore the prevalence and the spatial,temporal,and population distributions of GERD in the natural Chinese *** We searched Chinese and English databases for literature on the prevalence of GERD in the natural Chinese *** prevalence of GERD was pooled using a random-effects meta-analysis *** analysis was performed according to time,region,and *** used ArcGIS software to draw statistical maps and trend analysis *** autocorrelation analysis was carried out using Geoda *** correlation analysis was used to assess the spatial distribution relationship between GERD and upper digestive tract *** Altogether,70 studies involving 276014 individuals from 24 provinces of China were *** overall pooled prevalence of GERD was 8.7%(95%CI:7.5%-9.9%)in China's *** the past two decades,the prevalence of GERD in China has increased from 6.0%to 10.6%.GERD was more common in people aged 40-60,with body mass index≥24,and of Uygur *** prevalence was higher in the west and east than in the centre,and there may be a local spatial autocorrelation between the Qinghai-Tibet Plateau and the *** was correlated with gastric(r=0.421,P=0.041)and oesophageal tumours(r=0.511,P=0.011)in spatial *** GERD is becoming common in *** prevalence differs by region and *** development of appropriate strategies for the prevention and treatment of GERD is needed.

关键词： China Meta-analysis Gastroesophageal reflux disease Prevalence Epidemiology Spatiotemporal trends

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A review of surface roughness measurements based on laser speckle method

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Journal of Iron and Steel Research(International) 2023年第10期30卷 1897-1915页

作者： Mei-qi Shao Dong Xu Si-yi Li Xiao-gang Zuo Chang-ke Chen Gong-zhuang Peng jia-min zhang Xiao-chen Wang Quan Yang Institute of Engineering Technology University of Science and Technology BeijingBeijing 100083China Xinjiang Joinworld Co. Ltd.Urumqi 830000XinjiangChina

Surface roughness is commonly used to characterize material microstructure during processing,and accurate measurement of surface roughness is the premise and foundation of ***,online non-destructive measurement of surface roughness based on the laser speckle method has become a hot issue in recent *** improvements in surface roughness measurements based on the laser speckle method are systematically *** of speckle formation is *** statistical properties of the speckle patterns including first-order statistical properties and second-order statistical properties are directly related to surface *** roughness measurements based on the laser speckle method are roughly divided into the speckle contrast method,speckle correlation method,and fractal *** three methods are described in detail,and an extensive comparison among all the methods is *** recent progresses and application of surface roughness measurements are ***,surface roughness measurements based on the laser speckle method are prospected and summarized.

关键词： Surface roughness Non-destructive measurement Laser speckle method Speckle pattern Statistical property

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Primary acinic cell carcinoma of the breast: A case report and review of literature

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World Journal of Clinical Cases 2024年第1期12卷 196-203页

作者： jia-Sheng Ding min zhang Fang-Fang Zhou Department of Intensive Care Unit Lishui Central HospitalThe Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina Department of Pathology Lishui Central HospitalThe Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina Department of Ultrasound Lishui Central HospitalThe Fifth Affiliated Hospital of Wenzhou Medical UniversityLishui 323000Zhejiang ProvinceChina

BACKGROUND In the current World Health Organization classification,acinic cell carcinoma(AcCC)of the breast is considered a rare histological subtype of triple-negative breast *** of the few reports in the literature,data concerning clinical outcomes are ***,we report a case of AcCC of the breast in a 48-year-old woman.A 48-year-old woman with a mass in her right breast came to our hospital for further *** and an ultrasound(US)scan showed a mass in the upper inner side of the right *** then underwent surgery to resect the mass in her right *** pathological examination revealed that the tumor had abundant acinar-like structures formed by tumor cells with prominent eosinophilic granules in the cytoplasm,consistent with acinar cell *** results of immunohistochemical analysis supported the diagnosis of breast acinar cell *** months later,she underwent breast-conserving surgery and sentinel lymph node *** pTNM stage was *** surgery,the patient received 30 radiotherapy *** patient was followed up for a period of one year,and no recurrence was *** of the breast is a rare type of malignant *** it is usually asym-ptomatic and can be detected by imaging studies,routine breast US or mamm-ograms are ***,there are no characteristic diagnostic imaging findings or clinical manifestations,so immunohistochemical examination is critical for an accurate diagnosis of AcCC of the breast.

关键词： Acinic cell carcinoma Breast Malignant tumor Immunohistochemical Surgery Case report

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Nuclear transport receptors underpin plastidial retrograde signaling

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Molecular Plant 2024年第7期17卷 993-995页

作者： min jia Yangnan Gu Department of Plant and Microbial Biology University of CaliforniaBerkeleyBerkeleyCAUSA

The nucleus integrates cytosolic and organellar signals to regulate gene expression during plant stress responses,and this process is highly dependent on shuttling of signaling molecules in and out of the *** nucleocytoplasmic transport of macromolecules is facilitated by nuclear transport receptors(NTRs).NTRs are broadly categorized into exportins,which mediate the export of cargo from the nucleus to the cytoplasm,and importins,which facilitate the import of cargo into the *** importin family comprises importin-α(IMPa)and importin-β(IMPp).IMPa proteins are adaptor proteins and composed of three functional domains:an N-terminal IMPβ-binding(IBB)domain,ten Armadillo(ARM)repeats responsible for recognizing and interacting with cargo,and an exportin-interacting domain crucial for recycling via nuclear export(Wing et al.,2022).During a nuclear transport event,*** cargo containing a classical nuclear localization signal(cNLS)through its ARM repeats and engages IMPβvia its IBB domain,forming the cargo-IMPa-IMPβternary ***βfacilitates translocation of this complex through the nuclear *** inside the nucleus,RanGTP competes with IMPa for binding to IMPβ,promoting disassembly of the transport complex and releaseofcargo.

关键词： complex. integrate ternary

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Surface vitrification of carbon by laser treatment: Insights of glass formation from molecular dynamics

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Journal of Advanced Ceramics 2024年第6期13卷 729-735页

作者： Yanhui zhang Haifeng Yu Yongying jia Zhisheng Zhao Li-min Wang Riping Liu Center for Advanced Structural Materials State Key Laboratory of Metastable Materials Science and TechnologyYanshan UniversityQinhuangdao 066004China

Microstructural modification of carbon materials,such as carbon fibers(Cf)and pyrolytically deposited carbon,is important for engineering ***,the regulation of these materials is not an effortless *** understand the impacts of thermal spikes from pulsed laser processing on the structural adaptation of amorphous carbon(a-C),we performed melt quenching by molecular dynamics(MD)*** results confirm that the vitrification behavior of carbon can be tuned by adjusting the cooling rate(R),which is controlled by the thermal spikes of laser ***,we set up a two-step way to locate the critical cooling rate(R_(c))of monoatomic carbon,which is refined by the sharp change in the environmental similarity *** this novel technique,we demonstrate that the ordering degree and the local atomic motif can be largely modified by going across a bar of 100 K/ps,which is extracted as the critical cooling rate to ensure the complete amorphization of *** approach provides a criterion for both experimentally processing and theoretically simulating a-C ***,this work provides guidelines on how to tune the amorphous carbon structures of engineering materials and provides an outlook for the wonderland of amorphous carbon materials.

关键词： molecular dynamics(MD) structural order carbon fibers(Cf) vitrification critical cooling rate(R_(c))

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Road map for, and technical challenges of, carbon-nanotube integrated circuit technology

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National Science Review 2024年第3期11卷 14-16页

作者： jia Si Panpan zhang Zhiyong zhang Key Laboratory for the Physics and Chemistry of Nanodevices and Center for Carbon-based Electronics School of Electronics Peking University State Key Laboratory of Information Photonics and Optical Communications Beijing University of Posts and Telecommunications

The past decade has witnessed an explosion of research on carbon-nanotube(CNT) electronics due to their outstanding properties, including an ultrathin body, a high carrier mobility and a high saturation velocity.

关键词： TRANSISTORS

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Sedimentary architecture of submarine channel-lobe systems under different seafloor topography:Insights from the Rovuma Basin offshore East Africa

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Petroleum Science 2024年第1期21卷 125-142页

作者： Mei Chen Sheng-He Wu Rui-Feng Wang jia-jia zhang Peng-Fei Xie min Wang Xiao-Feng Wang Ji-Tao Yu Qi-Cong Xiong State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Faculty of Geosciences University of BremenBremen28359Germany MARUM-Center for Marine and Environmental Sciences University of BremenBremen28359Germany Research institute of Petroleum Exploration and Development PetroChinaBeijing10083China School of Geosciences Yangtze UniversityWuhan 100083HubeiChina CNODC Mozambique Ltd. Beijing 100034China

Seafloor topography plays an important role in the evolution of submarine ***,it is still not so clear how the shape of slope affects the three-dimensional(3-D)architecture of submarine *** this study,we analyze the effect of topography factors on different hierarchical lobe architectures that formed during Pliocene to Quaternary in the Rovuma Basin offshore East *** characterize the shape,size and growth pattern of different hierarchical lobe architectures using 3-D seismic *** find that the relief of the topographic slope determines the location of preferential deposition of lobe complexes and single *** the topography is irregular and presents topographic lows,lobe complexes first infill these *** lobes are deposited preferentially at positions with higher longitudinal(***-slope)slope *** the longitudinal slope becomes higher,the aspect ratio of the single lobes ***(***-slope)topography does not seem to have a strong influence on the shape of single lobe,but it seems to affect the overlap of single *** the lateral slope gradient is relatively high,the single lobes tend to have a larger overlap ***,as the average of lateral slope and longitudinal slope gets greater,the width/thickness ratio of the single lobe is smaller,*** tend to accumulate *** results demonstrate that the shape of slopes more comprehensively influences the 3-D architecture of lobes in natural deep-sea systems than previously other lobe deposits and analogue experiments,which helps us better understand the development and evolution of the distal parts of turbidite systems.

关键词： Submarine fan Seafloor topography Sedimentary architecture Slope system SW Indian ocean

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Anti-osteosarcoma trimodal synergistic therapy using NiFe-LDH and MXene nanocomposite for enhanced biocompatibility and efficacy

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1329-1344页

作者： Yani Xu Lan Yang min Li Haozhou Shu Na jia Yunzhen Gao Rongying Shi Xiaojia Yang Zhirong zhang Ling zhang Key Laboratory of Drug-Targeting and Drug Delivery System of the Education ministry West China School of PharmacySichuan UniversityChengdu 610041China Med-X Center for Materials College of Polymer Science and EngineeringSichuan UniversityChengdu 610065China

Osteosarcoma is usually resistant to immunotherapy and,thus primarily relies on surgical resection and high-dosage ***,less invasive or toxic therapies such as photothermal therapy(PTT)and chemodynamic therapy(CDT)generally failed to show satisfactory *** multimodal therapies with proper safety profiles may provide better solutions for ***,a simple nanocomposite that synergistically combines CDT,PTT,and chemotherapy for osteosarcoma treatment was *** this composite,small 2D Ni Fe-LDH flakes were processed into 3D hollow nanospheres via template methods to encapsulate 5-Fluorouracil(5-FU)with high loading *** nanospheres were then adsorbed onto larger 2D Ti3C2MXene monolayers and finally shielded by bovine serum albumin(BSA)to form 5-FU@Ni Fe-LDH/Ti3C2/BSA nanoplatforms(5NiTiB).Both in vitro and in vivo data demonstrated that the 5-FU induced chemotherapy,Ni Fe-LDH driven chemodynamic effects,and MXene-based photothermal killing collectively exhibited a synergistic“all-in-one”anti-tumor effect.5NiTiB improved tumor suppression rate fromminimizing side ***,the composite is simple to produce,enabling the fine-tuning of dosages to suit different ***,the platform is versatile and efficient,with potential for further development.

关键词： Osteosarcoma NiFe-LDH MXene Chemodynamic therapy Photothermal therapy Chemotherapy 5-Fluorouracil Nanocomposite

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On the Difference Between the Skew-rank of an Oriented Graph and the Rank of Its Underlying Graph

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Acta Mathematicae Applicatae Sinica 2024年第1期40卷 129-136页

作者： jia-min Zhu Bo-jun Yuan Yi Wang School of Mathematical Sciences Anhui UniversityHefei230601China School of Science Zhejiang University of Science and TechnologyHangzhou310023China

Let G be a simple graph and G~σ be the oriented graph with G as its underlying graph and orientation σ.The rank of the adjacency matrix of G is called the rank of G and is denoted by r(G).The rank of the skew-adjacency matrix of G~σ is called the skew-rank of G~σ and is denoted by sr(G~σ).Let V(G)be the vertex set and E(G) be the edge set of *** cyclomatic number of G,denoted by c(G),is equal to |E(G)|-|V(G)|+ω(G),where ω(G) is the number of the components of *** is proved for any oriented graph G~σ that-2c(G)≤sr(G~σ)-r(G)≤2c(G).In this paper,we prove that there is no oriented graph G~σwith sr(G~σ)-r(G)=2c(G)-1,and in addition,there are infinitely many oriented graphs G~σ with connected underlying graphs such that c(G)=k and sr(G~σ)-r(G)=2c(G)-l for every integers k,l satisfying 0 ≤l≤4k and l≠1.

关键词： cyclomatic number rank skew-rank

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Metal-based inorganic nanocrystals for biological sonodynamic therapy applications:recent progress and perspectives

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Rare Metals 2024年第2期43卷 413-430页

作者： Dong Wang jia-Tao zhang Institute of Medical-Industrial Integration Beijing Key Laboratory of Structurally Controllable Advanced Functional Materials and Green ApplicationsSchool of Materials Science and EngineeringBeijing Institute of TechnologyBeijing100081China Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering Ministry of Industry and Information TechnologySchool of Chemistry and Chemical EngineeringBeijing Institute of TechnologyBeijing100081China

With the fast development of technology for the treatment of tumor and bacteria,photo-therapeutic strate-gies emerge as a kind of highly effective and common treatment,but the low tissue penetration depth of light limits their *** therapy(SDT),as an efficient and non-invasive treatment,attracts more people's attention due to the inherent property of high tissue *** soft tissue penetration depth of ultrasound(US)can even reach more than 10 cm,which has great advantage over that of ***,many sonosensitizers are studied and applied to SDT-based ***-based inorganic nanocrystals are able to generate more reactive oxygen species(ROS)due to the special composition and band *** representative achievements and the specific functions of the nanocrystals sonosensitizers are summarized in this work,and the relationship of structure/composition-SDT performance and the internally regulated composite is ***-gistic effects of SDT in combination with other therapeutic modalities are mainly *** the same time,the critical and potential issues and future perspectives are addressed.

关键词： Metal-based inorganic nanocrystals Sonodynamic therapy(SDT) Tumor treatment Antibacteria

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