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Plume-lithosphere interaction in the Comei Large Igneous Province: Evidence from two types of mafic dykes in Gyangze, south Tibet, China

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China Geology 2024年第1期7卷 80-90页

作者： Ya-ying Wang Ling-sen Zeng Li-e gao Li-long Yan Ling-hao Zhao jia-hao gao Ying-long Di Guang-xu Li Yi-hong Tian Institute of Geology Chinese Academy of Geological SciencesBeijing 100037China National Research Center for Geoanalysis Chinese Academy of Geological SciencesBeijing 100037China China Nonferrous Metals(Guilin)Geology and Mining Co. LtdGuilin 541004China

Two suites of mafic dykes,T1193-A and T1194-A,outcrop in Gyangze area,southeast Tibet.They are in the area of Comei LIP and have indistinguishable field occurrences with two other dykes in Gyangze,T0902 dyke with 137.7±1.3 Ma zircon age and T0907 dyke with 142±1.4 Ma zircon age reported by Wang YY et al.(2016),indicating coeval formation time.Taking all the four diabase dykes into consideration,two different types,OIB-type and weak enriched-type,can be summarized.The“OIB-type”samples,including T1193-A and T0907 dykes,show OIB-like geochemical features and have initial Sr-Nd isotopic values similar with most mafic products in Comei Large Igneous Provinces(LIP),suggesting that they represent melts directly generated from the Kerguelen mantle plume.The“weak enriched-type”samples,including T1194-A and T0902 dykes,have REEs and trace element patterns showing withinplate affinity but have obvious Nb-Ta-Ti negative anomalies.They show uniform lowerεNd(t)values(−6‒−2)and higher 87Sr/86Sr(t)values(0.706‒0.709)independent of their MgO variation,indicating one enriched mantle source.Considering their closely spatial and temporal relationship with the widespread Comei LIP magmatic products in Tethyan Himalaya,these“weak enriched-type”samples are consistent with mixing of melts from mantle plume and the above ancient Tethyan Himalaya subcontinental lithospheric mantle(SCLM)in different proportions.These weak enriched mafic rocks in Comei LIP form one special rock group and most likely suggest large scale hot mantle plume-continental lithosphere interaction.This process may lead to strong modification of the Tethyan Himalaya lithosphere in the Early Cretaceous.

关键词： OIB type diabase Comei Large Igneous Province Weakly enriched diabase Plume-lithosphere interaction Nb-Ta-Ti negative anomaly Kerguelen plume Geological survey engineering Tibet Plateau

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Behavior of apatite in granitic melts derived from partial melting of muscovite in metasedimentary sources

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China Geology 2021年第1期4卷 44-55页

作者： Li-E gao Ling-sen Zeng Ling-hao Zhao jia-hao gao Zhen Shang Key Laboratory of Deep-Earth Dynamics of Ministry of Natural Resources Institute of GeologyChinese Academy of Geological SciencesBeijing 100037China National Research Center for Geoanalysis Chinese Academy of Geological ScienceBeijing 100037China

Fluid-absent and fluid-fluxed melting of muscovite in metasedimentary sources are two types of crustal anatexis to produce the Himalaya Cenozoic leucogranites.Apatite grains separated from melts derived from the two types of parting melting have different geochemical compositions.The leucogranites derived from fluid-fluxed melting have relict apatite grains and magmatic crystallized apatite grains,by contrast,there are only crystallized apatite grains in the leucogranites derived from fluid-absent melting.Moreover,apatite grains crystallized from fluid-fluxed melting of muscovite contain higher Sr,but lower Th and LREE than those from fluid-absent melting of muscovite,which could be controlled by the distribution of partitioning coefficient(D_(Ap/Melt))between apatite and leucogranite.D_(Ap/Melt) in granites derived from fluidabsent melting is higher than those from fluid-fluxed melting.So,not only SiO_(2) and A/CNK,but also types of crustal anatexis are sensitive to trace element partition coefficients for apatite.In addition,due to being not susceptible to alteration,apatite has a high potential to yield information about petrogenetic processes that are invisible at the whole-rock scale and thus is a useful tool as a petrogenetic indicator.

关键词： Apatite Partitioning coefficient Crustal anatexis Leucogranite Malashan Dome Tethyan Himalaya Geological survey engineering Tibet

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Baddeleyite and zircon U-Pb ages of the ultramafic rocks in Chigu Tso area,Southeastern Tibet and their constraints on the timing of Comei Large Igneous Province

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China Geology 2020年第2期3卷 262-268页

作者： Ya-ying Wang Ling-sen Zeng Ling-hao Zhao Li-e gao jia-hao gao Zhao-ping Hu Hai-tao Wang Guang-xu Li Ying-long Di Yu Shen Qian Xu Institute of Geology Chinese Academy of Geological SciencesMinistry of Natural ResourcesBeijing 100037China National Research Center for Geoanalysis Chinese Academy of Geological SciencesMinistry of Natural ResourcesBeijing 100037China

A suite of ultramafic and mafic rocks developed in the Chigu Tso area,eastern Tethyan Himalaya.Baddeleyite and zircon U-Pb ages acquired by SIMS and LA-ICP-MS from olivine pyroxenite rocks in the Chigu Tso area are 138.9±3.0 Ma and 139.0±1.9 Ma,respectively.These two Early Cretaceous ages are similar with the ages of the more abundant mafic rocks in the eastern Tethyan Himalaya,indicating that this suite of ultramafic and mafic rocks in the Chigu Tso area should be included in the outcrop area of the Comei Large Igneous Province(LIP).These ultramafic rocks provide significant evidence that the involvement of mantle plume/hot spot activities in the formation of the Comei LIP.Baddeleyite U-Pb dating by SIMS is one reliable and convenient method to constrain the formation time of ultramafic rocks.The dating results of baddeleyite and zircon from the olivine pyroxenite samples in this paper are consistent with each other within analytical uncertainties,suggesting that baddeleyite and zircon were both formed during the same magmatic process.The consistency of baddeleyite U-Pb ages in the Chigu Tso area with zircon U-Pb ages for a large number of Early Cretaceous mafic rocks in the eastern Tethyan Himalaya further support that zircon grains from such mafic rocks yielding Early Cretaceous ages are also magmatic in origin.

关键词： U-Pb dating Baddeleyite Zircon Ultramafic rock Comei Large Igneous Province Kerguelen plume Tethyan Himalaya Geological survey engineering Tibet China

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Intestinal malrotation complicated with gastric cancer: A case report

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World Journal of Clinical Cases 2024年第1期12卷 210-216页

作者： Xiang-hao jia Shuai Kong Xin-Xin gao Bi-Cong Cong Chun-Ning Zheng School of Clinical Medicine Weifang Medical UniversityWeifang 261053Shandong ProvinceChina Department of Gastrointestinal Surgery Provincial Hospital Affiliated to Shandong First Medical UniversityJinan 250000Shandong ProvinceChina

BACKGROUND Intestinal malrotation is a congenital defect of embryonic development caused by various teratogenic factors.In this condition,the intestinal tube,along with the superior mesenteric artery serving as the axis for the counterclockwise movement,is incomplete or abnormally rotated due to incomplete attachment of the mesentery and abnormal intestinal tube position.Such a case is usually asymp-tomatic and thus difficult to detect.Therefore,similar variant malformations are only found during an operation required for other abdominal diseases.CASE SUMMARY An elderly male patient was admitted to the hospital due to gastric cancer.An abdominal computed tomography(CT)scan with contrast revealed that the ascending and descending colon were parallel on the right side of the abdominal cavity,while the sigmoid colon extended into the right iliac fossa,allowing the diagnosis of congenital midgut malrotation.Following thorough preoperative preparation,the patient underwent laparoscopic radical gastrectomy to treat his gastric cancer.Intraoperatively,an exploration of the abdominal cavity uncovered the absence of the transverse colon.The distal colon at the hepatic flexure,along with the ascending colon,extended into the right iliac fossa,where it continued as the sigmoid colon.As planned,the laparoscopic radical gastrectomy was perform-ed,and the patient was discharged from the hospital 7 d after the surgery.CONCLUSION Asymptomatic intestinal malrotation is best detected by CT,requiring no treatment but possibly interfering with the treatment of other diseases.

关键词： Intestinal malrotation Congenital malformation Gastric cancer Abdominal

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A compact X-band backward traveling-wave accelerating structure

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Nuclear Science and Techniques 2024年第5期35卷 13-29页

作者： Xian-Cai Lin hao Zha jia-Ru Shi Qiang gao Fang-Jun Hu Qing-Zhu Li Huai-Bi Chen Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Particle and Radiation Imaging(Tsinghua University) Ministry of EducationBeijing 100084China

Very high-energy electrons(VHEEs)are potential candidates for FLASH radiotherapy for deep-seated tumors.We proposed a compact VHEE facility based on an X-band high-gradient high-power technique.In this study,we investigated and realized the first X-band backward traveling-wave(BTW)accelerating structure as the buncher for a VHEE facility.A method for calculating the parameters of single cell from the field distribution was introduced to simplify the design of the BTW structure.Time-domain circuit equations were applied to calculate the transient beam parameters of the buncher in the unsteady state.A prototype of the BTW structure with a thermionic cathode-diode electron gun was designed,fabricated,and tested at high power at the Tsinghua X-band high-power test stand.The structure successfully operated with 5-MW microwave pulses from the pulse compressor and outputted electron bunches with an energy of 8 MeV and a pulsed current of 108 mA.

关键词： Backward traveling-wave accelerating structure Equivalent circuit model High-power test Very high-energy electron radiotherapy

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Emerging clinical relevance of microbiome in cancer:promising biomarkers and therapeutic targets

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Protein & Cell 2024年第4期15卷 239-260页

作者： jia-hao Dai Xi-Rong Tan Han Qiao Na Liu State Key Laboratory of Oncology in South China Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangdong Provincial Clinical Research Center for CancerSun Yat-sen University Cancer CenterGuangzhou 510050China

The profound influence of microbiota in cancer initiation and progression has been under the spotlight for years,leading to numerous researches on cancer microbiome entering clinical evaluation.As promising biomarkers and therapeutic targets,the critical involvement of microbiota in cancer clinical practice has been increasingly appreciated.Here,recent progress in this field is reviewed.We describe the potential of tumor-associated microbiota as effective diagnostic and prognostic biomarkers,respectively.In addition,we highlight the relationship between microbiota and the therapeutic efficacy,toxicity,or side effects of commonly utilized treatments for cancer,including chemotherapy,radiotherapy,and immunotherapy.Given that microbial factors influence the cancer treatment outcome,we further summarize some dominating microbial interventions and discuss the hidden risks of these strategies.This review aims to provide an overview of the applications and advancements of microbes in cancer clinical relevance.

关键词： microbiome cancer diagnosis prognosis therapy

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Intermittent Theta Burst Stimulation Attenuates Cognitive Deficits and Alzheimer’s Disease-Type Pathologies via ISCA1-Mediated Mitochondrial Modulation in APP/PS1 Mice

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Neuroscience Bulletin 2024年第2期40卷 182-200页

作者： Yang Zhu hao Huang Zhi Chen Yong Tao Ling-Yi Liao Shi-hao gao Yan-jiang Wang Chang-Yue gao Department of Rehabilitation Medicine Daping HospitalArmy Medical UniversityChongqing 400042China Department of Neurology and Center for Clinical Neuroscience Daping HospitalArmy Medical UniversityChongqing 400042China Department of Special Medicine Daping HospitalArmy Medical UniversityChongqing 400042China

Intermittent theta burst stimulation(iTBS),a time-saving and cost-effective repetitive transcranial magnetic stimulation regime,has been shown to improve cognition in patients with Alzheimer’s disease(AD).However,the specific mechanism underlying iTBS-induced cognitive enhancement remains unknown.Previous studies suggested that mitochondrial functions are modulated by magnetic stimulation.Here,we showed that iTBS upregulates the expression of iron-sulfur cluster assembly 1(ISCA1,an essential regulatory factor for mitochondrial respiration)in the brain of APP/PS1 mice.In vivo and in vitro studies revealed that iTBS modulates mitochondrial iron-sulfur cluster assembly to facilitate mitochondrial respiration and function,which is required for ISCA1.Moreover,iTBS rescues cognitive decline and attenuates AD-type pathologies in APP/PS1 mice.The present study uncovers a novel mechanism by which iTBS modulates mitochondrial respiration and function via ISCA1-mediated iron-sulfur cluster assembly to alleviate cognitive impairments and pathologies in AD.We provide the mechanistic target of iTBS that warrants its therapeutic potential for AD patients.

关键词： Intermittent theta burst stimulation Alzheimer’s disease Iron-sulfur cluster assembly 1 Mitochondrial dysfunction Neurodegeneration

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Study of the multi-physics field-coupled model of the two-stage electrostatic precipitator

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Building Simulation 2024年第3期17卷 387-398页

作者： Wenjia hao Yu Guo Yukun Wang Tao Yu hao gao Zhengwei Long Tianjin Key Laboratory of Indoor Air Environmental Quality Control School of Environmental Science and EngineeringTianjin UniversityWeijin Road 92Tianjin300072China Wuhan Second Ship Design and Research Institute WuhanChin

The two-stage electrostatic precipitator is widely used to purify oil mist particles.However,there is limited research on the influences of relative humidity,particle deposition characteristics,and the generation of gaseous pollutants.Therefore,this paper established a numerical model of the electrostatic oil mist purifier and applied it to a two-stage electrostatic precipitator.Then the model was used to investigate the corona discharge characteristics under different relative humidity conditions in the charged zone,the particle deposition characteristics,the purification efficiency,the ozone concentration distribution,and the oil vapor concentration distribution in the collection zone.The results indicate that,with a constant temperature,the corona current decreases as relative humidity increase,and there is a quadratic relationship between relative humidity and current.The variation in relative humidity has little impact on the purification efficiency.The maximum ozone concentration occurs near the electrode line,and its concentration is influenced by the discharge current and inlet airflow velocity.The oil vapor concentration reaches its maximum value at the side plates,with a value of 19 ppb,while it reaches the minimum value at the collecting zone electrode plate,with a value of 2 ppb.The temperature is the main factor affecting the volatilization of the oil film,with higher temperatures resulting in higher oil vapor.

关键词： two-stage ESPs particle deposition corona discharge oil vapor

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Effects of combustion temperature on the optical properties of brown carbon from biomass burning

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Journal of Environmental Sciences 2024年第3期137卷 302-309页

作者： Peng gao Rule Deng Song jia Yue Li Xuefei Wang Qian Xing School of Chemistry Sciences University of Chinese Academy of SciencesBeijing 100049China College of Chemistry and Materials Engineering Beijing Technology and Business UniversityBeijing 100048China

Biomass burning has been known as one of main sources of Brown Carbon(BrC)in atmosphere.In this study,by controlling the combustion temperature at 250℃,350℃,and 450℃,the methanol soluble organic carbon(MSOC)and methanol insoluble carbon(MISC)from pine wood burning was collected by impinger.UV–Vis,excitation emission matrix(EEM),TEM and FTIR spectra were applied to investigate the properties of BrC collected.For MSOC at 250℃ and 350℃,all the spectral profiles of UV–Vis absorption and excitation emission matrix are almost the same,while the EEM of MSOC at 450℃ are different from that of the other two.For MISC fuorescence was observed only in the case of 450℃.In the FTIR spectra,with the temperature increasing the peaks associated to the oxygen-contained functions was weakened,indicating the formation of the fuorophores with larger conjugated system,especially aromatic hydrocarbons.Our results show that biomass combustion at low temperature produces more oxygen-riched BrC,which possesses relatively lower light absorption,while at high temperature produces more aromatics hydrocarbons with relatively strong light absorption.The results of this work are helpful to trace the source of brown carbon and optimize biomass energy utilization.

关键词： Biomass burning Combustion temperature Methanol-soluble brown carbon EEM Impinger

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Climatic impacts induced by winter wheat irrigation over North China simulated by the nonhydrostatic RegCM4.7

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Advances in Climate Change Research 2024年第2期15卷 197-210页

作者： jia WU Zhen-Yu HAN Xue-Jie gao Zheng-jia LIU National Climate Centre China Meteorological AdministrationBeijing 100081China Key Laboratory for Climate Studies China Meteorological AdministrationBeijing 100081China Climate Change Research Center Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and TechnologyNanjing 210044China Institute of Geographic Sciences and Natural Resources Research Chinese Academy of SciencesBeijing 100101China

Quantification of the impact of winter wheat irrigation on the climate and the occurrence of extreme climatic events over North China is crucial for regional adaptation planning.Previous related studies mainly focused on the impact on surface processes;however,few focused on the effects of extreme events using high-resolution nonhydrostatic regional climate models.Here,the 9-km-resolution nonhydrostatic RegCM4.7 was coupled with a crop irrigation scheme and an updated winter wheat irrigation dataset to better simulate irrigation effects.Two experiments were conducted with and without winter wheat irrigation to isolate the effects of irrigation.Results showed that irrigation simulation reduces the model biases in temperature,precipitation,latent heat flux,soil moisture,sensitive heat flux,and top-layer soil moisture.Moreover,it also reduces the bias and increases the correlation with observations obtained in irrigated areas,especially in summer,indicating better representation of irrigation schemes.Winter wheat irrigation tends to cause substantial cooling of the local surface maximum,minimum,and mean air temperatures(by-1.68,-0.34,and-0.79℃,respectively)over irrigated areas of North China,with the largest changes observed in relation to maximum temperature.Additionally,precipitation is found to increase during spring and summer,which is strongly related to water vapor transport in the lower levels of the atmosphere.Further analyses indicated that the number of annual mean hot days decrease(-13.9 d),whereas the number of both comfort days(+10.2 d)and rainy days(days with total precipitation greater than 1 mm:+6.6 d)increase over irrigated areas,demonstrating beneficial feedback to human perception and agriculture.Fortunately,although the heat wave risk increases(number of annual mean heat wave days:+5.8 d),the impact is limited to small areas within irrigated region.Additionally,no notable change was found in terms of heavy rainfall events and precipitation intensity,which might be an undereastimation caused by th

关键词： Nonhydrostatic regional climate model Irrigation effect Extreme events North China

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