检索结果-南通市图书馆

Efficacy of transjugular intrahepatic portosystemic shunts in treating cirrhotic esophageal-gastric variceal bleeding

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第2期16卷 471-480页

作者： Xiao-Gang Hu jian-ji Dai Jun lu Gang li jia-Min Wang Yi Deng Rui feng Kai-Ping lu department of Interventional Radiology The Affiliated Jinhua HospitalZhejiang University School of MedicineJinhua 321000Zhejiang ProvinceChina department of Interventional Medicine Zhejiang Provincial People’s HospitalPeople’s Hospital of Hangzhou Medical CollegeHangzhou 310000Zhejiang ProvinceChina department of Vascular Surgery Zhejiang Provincial People’s HospitalPeople’s Hospital of Hangzhou Medical CollegeHangzhou 310000Zhejiang ProvinceChina

BACKGROUND Esophageal-gastric variceal bleeding(EGVB)represents a severe complication among patients with cirrhosis and often culminates in fatal ***-tional therapy,a rapidly developing treatment modality over the past few years,has found widespread application in clinical practice due to its minimally inva-sive ***,whether transjugular intrahepatic portosystemic shunt(TIPS)treatment has an impact on patient prognosis remains *** A retrospective study was conducted on ninety-two patients presenting with cirrhotic EGVB who were admitted to our hospital between September 2020 and September *** on the different modes of treatment,the patients were assigned to the study group(TIPS received,n=50)or the control group(per-cutaneous transhepatic varices embolization received,n=42).Comparative ana-lyses were performed between the two groups preoperatively and one month postoperatively for the following parameters:Varicosity status;hemodynamic parameters[portal vein flow velocity(PVV)and portal vein diameter(PVD);platelet count(PlT);red blood cell count;white blood cell count(WBC);and hepatic function[albumin(AlB),total bilirubin(TBIl),and aspartate transaminase(AST)].The Generic Quality of life Inventory-74 was utilized to assess quality of life in the two groups,and the 1-year postoperative rebleeding and survival rates were *** Following surgical intervention,there was an improvement in the incidence of varicosity compared to the preoperative status in both ***,the study group exhibited more pronounced enhancements than did the control group(Phe preoperative values,with the study cohort achieving better outcomes(PlT and WBC counts were elevated postoperatively in the two groups,with the study cohort displaying higher PlT and WBC counts(Pdifferences were detected between the two groups in terms of serum AlB,TBIl,or AST lev

关键词： liver cirrhosis Esophagogastric variceal bleeding Transjugular intrahepatic portosystemic shunt Prognosis

divergent changes in diversity and network complexity across different trophic-level organisms drive soil multifunctionality of fire-impacted subtropical forests

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Forest Ecosystems 2024年第5期11卷 697-707页

作者： luhong Zhou Shangshi liu Debao lin Hang-wei Hu ji-Zheng he Key laboratory for Humid Subtropical Eco-geographical Processes of the Ministry of Education School of Geographical SciencesFujian Normal UniversityFuzhou350007China department of Earth and Environmental Sciences University of ManchesterOxford RoadManchesterM139PTUK School of Agriculture Food and Ecosystem SciencesFaculty of ScienceThe University of MelbourneParkville3010Australia

Widespread forest fires pose significant challenges to the diverse communities of soil-dwelling organisms and the multiple ecosystem functions they ***,whether the biodiversity and interactions of various taxonomic groups respond to fire consistently in terms of direction and extent,and their relative role in regulating post-fire soil functioning,remains largely *** this study,we investigated whether the diversity and co-occurrence networks of soil organisms across various trophic levels(including bacteria,fungi,protists,and invertebrates)in subtropical forests exhibit consistent responses to ***,we investigated their contribution to regulating soil multifunctionality,which is measured by a range of soil extracellular enzyme activities,available nutrients and reduced potential fungal plant *** findings revealed that fire led to a decline in the richness of fungi,protists,and invertebrates,without significantly impacting bacterial *** also simplified the microbial co-occurrence networks while complexifying the invertebrate ***,soil multifunctionality tended to decrease with the richness of lower-trophic communities(i.e.,bacteria),whereas it increased with that of high-trophic communities(i.e.,protists and invertebrates).Moreover,fire indirectly influenced soil multifunctionality by altering biodiversity and network complexity,particularly pronounced in high-trophic ***,our results underscored the divergent vulnerability of biodiversity and networks to fires across taxa groups,highlighting the crucial role of biodiversity and interactions of higher trophic taxa groups in shaping the recovery and functionality of fire-affected soils.

关键词： Invertebrates Microorganism Multifunctionality Protists Wildfire

Rapid fabrication of modular 3D paper-basedmicrofluidic chips using projection-based 3D printing

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bio-Design and Manufacturing 2024年第5期7卷 611-623页

作者： mingjun Xie Zexin Fu Chunfei lu Sufan Wu lei Pan Yong he Yi Sun ji Wang Plastic and Reconstructive Surgery Center Department of Plastic and Reconstructive SurgeryZhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhou 310014China State Key laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310058China Key laboratory of Materials Processing and Mold Zhengzhou UniversityZhengzhou 450002China Key laboratory of 3D Printing Process and Equipment of zhejiang Province College of Mechanical EngineeringZhejiang UniversityHangzhou 310058China Cancer Center Zhejiang UniversityHangzhou 310058China

Paper-based microchips have different advantages,such as better biocompatibility,simple production,and easy handling,making them promising candidates for clinical diagnosis and other *** study describes amethod developed to fabricate modular three-dimensional(3D)paper-based microfluidic chips based on projection-based 3D printing(PBP)technology.A series of two-dimensional(2D)paper-based microfluidic modules was designed and *** evaluating the effect of exposure time on the accuracy of the flow channel,the resolution of this channel was experimentally ***,several 3D paper-based microfluidic chips were assembled based on the 2D ones using different methods,with good channel ***-based 2D and hydrogel-based 3D cell culture systems based on 3D paper-based microfluidic chips were verified to be ***,by combining extrusion 3D bioprinting technology and the proposed 3D paper-based microfluidic chips,multiorgan microfluidic chips were established by directly printing 3D hydrogel structures on 3D paperbased microfluidic chips,confirming that the prepared modular 3D paper-based microfluidic chip is potentially applicable in various biomedical applications.

关键词： Paper-based microfluidic chip Projection-based 3D printing(PBP) Modularization Cell culture

Safflower Yellow Inhibits Progression of hepatocellular Carcinoma by Modulating Immunological Tolerance via FAK Pathway

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Integrative Medicine 2024年第4期30卷 339-347页

作者： ji Hua-feng YANG Zi-qiang HAN Jun-jun lI he-fang jiN Zhao-qing CheN wei-qing CheN Fei-hua GONG Mou-chun department of General Surgery First People's Hospital of Hangzhou Lin'an DistrictHangzhou(311300)China

Objective To explore the anti-tumor effect of safflower yellow(SY)against hepatocellular carcinoma(HCC)and the underlying potential *** An in vitro model was established by mixing luc-hepa1-6 cells and CD3^(+)CD8^(+)T cells,followed by adding programmed cell death protein 1(PD-1)antibody(Anti-mPD-1)with or without *** apoptosis was detected by flow cytometry and the level of inflammatory cytokines was determined by enzyme-linked immunosorbent *** protein levels of programmed cell death 1 ligand 1(PD-l1),chemokine ligand(CCl5),C-X-C motif chemokine ligand 10(CXCl10)were measured by Western *** in situ animal model was established in mice followed by treatment with anti-mPD-1 with or without *** imaging was monitored with an AniView 100 imaging *** establish the FAK-overexpressed luc-hepa1-6 cells,cells were transfected with adenovirus containing pcDNA3.1-FAK for 48 *** The fluorescence intensity,apoptotic rate,release of inflammatory cytokines,and CCl5/CXCl10 secretion were dramatically facilitated by anti-mPD-1(Pl1 axis,which were extremely further enhanced by SY(Pluorescence intensity,elevated percentage of CD3+CD8+T cells,facilitated release of inflammatory cytokines,inactivated PD-1/PD-l1 axis,and increased CCl5/CXCl10 secretion were observed in Anti-mPD-1 treated mice(Ply enhanced by SY(Phermore,the enhanced effects of SY on inhibiting tumor cell growth,facilitating apoptosis and inflammatory cytokine releasing,suppressing the PD-1/PD-l1 axis,and inducing the CCl5/CXCl10 secretion in Anti-mPD-1 treated mixture of luc-hepa1-6 cells and CD3+CD8+T cells were abolished by FAK overexpression(Plusion SY inhibited the progression of HCC by mediating immunological tolerance through inhibiting FAK.

关键词： hepatocellular carcinoma safflower yellow Chinese medicine tumor microenvironment programmed cell death protein 1 focal adhesion kinase

Recent Advances in Electrochemical-Based Silicon Production Technologies with Reduced Carbon Emission

在线全文

学校读者我要写书评

暂无评论

Research 2024年第1期2023卷 209-236页

作者： feng Tian Zhongya Pang Shen Hu Xueqiang Zhang Fei Wang wei Nie Xuewen Xia Guangshi li Hsien-Yi Hsu Qian Xu Xingli Zou li ji Xionggang lu State Key laboratory of Advanced Special Steel&Shanghai Key laboratory of Advanced Ferrometallurgy&School of Materials Science and Engineering Shanghai University99#Shangda RoadShanghai 200444China Center for Hydrogen Metallurgy Technology Shanghai UniversityShanghai 200444China State Key laboratory of ASIC and System School of MicroelectronicsFudan University220#Handan RoadShanghai 200433China School of Energy and Environment Department of Materials Science and EngineeringCity University of Hong KongKowloon TongHong KongChina

Sustainable and low-carbon-emission silicon production is currently one of the main focuses for the metallurgical and materials science ***,considered a promising strategy,has been explored to produce silicon due to prominent advantages:(a)high electricity utilization efficiency;(b)low-cost silica as a raw material;and(c)tunable morphologies and structures,including films,nanowires,and *** review begins with a summary of early research on the extraction of silicon by *** has been placed on the electro-deoxidation and dissolution–electrodeposition of silica in chloride molten salts since the 21st century,including the basic reaction mechanisms,the fabrication of photoactive Si films for solar cells,the design and production of nanoSi and various silicon components for energy conversion,as well as storage ***,the feasibility of silicon electrodeposition in room-temperature ionic liquids and its unique opportunities are *** this basis,the challenges and future research directions for silicon electrochemical production strategies are proposed and discussed,which are essential to achieve large-scale sustainable production of silicon by electrochemistry.

关键词： directions electrodeposition electricity

Applying dynamic light scattering to investigate the self-assembly process of DNA nanostructures

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical letters 2024年第3期35卷 316-320页

作者： wei Yuan Gui-Zhi Dong Hui Ning Xiang-Xiang Guan jia-feng Cheng Zi-wei Shi Xiu-ji Du Si-Wen Meng Dong-Sheng liu Yuan-Chen Dong CAS Key laboratory of Colloid Interface and Chemical ThermodynamicsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China university of Chinese Academy of Sciences Beijing 100049China Dandong Bettersize Instruments ltd. Dandong 118000China Key laboratory of Organic Optoelectronics&Molecular Engineering of the Ministry of Education Department of ChemistryTsinghua UniversityBeijing 100084China department of Chemistry Renmin University of ChinaBeijing 100872China

Understanding the dynamic assembly process of DNA nanostructures is important for developing novel strategy to design and construct functional *** this work,temperature-controlled dynamic light scattering(DlS)strategy has been applied to study the global assembly process of DNA origami and DNA *** the temperature dependent size and intensity profiles,the self-assembly process of various DNA nanostructures with different morphologies have been well-studied and the temperature transition ranges could be *** advantage of the DlS information,rapid preparation of the DNA origami and the brick assembly has been realized through a constant temperature *** results demonstrate that the DlS-based strategy provides a convenient and robust tool to study the dynamic process of forming hieratical DNA structures,which will benefit understanding the mechanism of self-assembly of DNA nanostructures.

关键词： Dynamic light scattering Self-assembly process DNA nanostructures Temperature transition ranges Rapid preparation

Correlation between serum markers and transjugular intrahepatic portosystemic shunt prognosis in patients with cirrhotic ascites

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第2期16卷 481-490页

作者： Xiao-Gang Hu Xiao-Xian Yang Jun lu Gang li jian-ji Dai jia-Min Wang Yi Deng Rui feng department of Interventional Radiology The Affiliated Jinhua HospitalZhejiang University School of MedicineJinhua 321000Zhejiang ProvinceChina Medical College Jinhua PolytechnicJinhua 321017Zhejiang ProvinceChina department of Interventional Medicine Zhejiang Provincial People’s HospitalPeople’s Hospital of Hangzhou Medical CollegeHangzhou 310000Zhejiang ProvinceChina

BACKGROUND Individuals with refractory ascites in the context of liver cirrhosis typically face an adverse *** transjugular intrahepatic portosystemic shunt(TIPS)is an efficacious intervention,but there is a lack of reliable tools for postoperative pro-gnosis *** utilized clinical biochemical markers,such as the serum albumin concentration(Alb),sodium(Na+)concentration,and serum creatinine(Scr),have limited predictive ***,the quest for novel,specific biomarkers to evaluate the post-TIPS prognosis in patients with liver cirrhosis and refractory ascites holds significant practical importance.A retrospective analysis was conducted on 75 patients with liver cirrhosis and refractory ascites who underwent TIPS at our institution from August 2019 to August *** patients were followed up regularly for two years,and the death toll was meticulously *** patients were allocated into a survival group(n=45 patients)or a deceased group(n=30 patients)based on their prognosis *** clinical data of the two groups were collected,and Child-Pugh scores and MElD scores were calculated for *** correlation analysis was carried out to evaluate the correlation of prognosis with Child-Pugh grade,MElD score,and Cys C ***,a multiple-factor analysis utilizing the Cox proportional hazard model was used to identify independent risk factors affecting the post-TIPS prognosis of patients with liver cirrhosis and refractory *** receiver operating characteristic curve(ROC)ascertained the predictive value of the Cys C concen-tration,Child-Pugh grade,and MElD score for the prognosis of liver cirrhosis with refractory ascites in post-TIPS *** During a 2-year follow-up period,among 75 patients with liver cirrhosis and refractory ascites who underwent TIPS treatment,30 patients(40.00%)passed *** deceased cohort exhibited heightened aspartate aminotrans-ferase,alanine aminotransferase,total b

关键词： liver cirrhosis Refractory ascites Transjugular intrahepatic portosystemic shunt Cystatin C

MOF‐derived 1D/3D N‐doped porous carbon for spatially confined electrochemical CO2 reduction to adjustable syngas

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Carbon Energy 2024年第8期6卷 1-13页

作者： wei Zhang Hui li Daming feng Chenglin Wu Chenghua Sun Baohua jia Xue liu Tianyi Ma Key laboratory for Green Synthesis and Preparative Chemistry of Advanced Materials Institute of Clean Energy ChemistryCollege of ChemistryLiaoning UniversityShenyangLiaoningChina School of Science RMIT UniversityMelbourneVictoriaAustralia School of Pharmaceutical and Chemical Engineering Taizhou UniversityTaizhouZhejiangChina department of Chemistry and Biotechnology Swinburne University of TechnologyHawthornVictoriaAustralia

Electrochemical reduction of CO_(2)to syngas(CO and H_(2))offers an efficient way to mitigate carbon emissions and store intermittent renewable energy in ***,the hierarchical one‐dimensional/three‐dimensional nitrogen‐doped porous carbon(1D/3D NPC)is prepared by carbonizing the composite of Zn‐MOF‐74 crystals in situ grown on a commercial melamine sponge(MS),for electrochemical CO_(2)reduction reaction(CO_(2)RR).The 1D/3D NPC exhibits a high CO/H_(2)ratio(5.06)and CO yield(31 mmol g^(−1)h^(−1))at−0.55 V,which are 13.7 times and 21.4 times those of 1D porous carbon(derived from Zn‐MOF‐74)and N‐doped carbon(carbonized by MS),*** is attributed to the unique spatial environment of 1D/3D NPC,which increases the adsorption capacity of CO_(2)and promotes electron transfer from the 3D N‐doped carbon framework to 1D carbon,improving the reaction kinetics of CO_(2)*** results and charge density difference plots indicate that the active site of CO_(2)RR is the positively charged carbon atom adjacent to graphitic N on 1D carbon and the active site of heR is the pyridinic N on 1D *** presence of pyridinic N and pyrrolic N reduces the number of electron transfer,decreasing the reaction kinetics and the activity of CO_(2)*** CO/H_(2)ratio is related to the distribution of N species and the specific surface area,which are determined by the degree of spatial confinement *** CO/H_(2)ratios can be regulated by adjusting the carbonization temperature to adjust the degree of spatial confinement *** the low cost of feedstock and easy strategy,1D/3D NPC catalysts have great potential for industrial application.

关键词： electrochemical CO_(2)reduction reaction melamine sponge metal‐organic frameworks porous carbon syngas

Electro-mechanical response of functionally graded beams with imperfectly integrated surface piezoelectric layers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science china(Physics,Mechanics & Astronomy) 2006年第5期49卷 513-525页

作者： YAN wei1 & CheN weiqiu1,2 1. department of Civil Engineering, zhejiang university, hangzhou 31002., china 2. State Key lab of CAD & CG, zhejiang university, hangzhou 31002., china 1. department of Civil Engineering Zhejiang University Hangzhou 310027 China 2. State Key lab of CAD & CG Zhejiang University Hangzhou 310027 China

The time-dependent behavior of a simply-supported functionally graded beam bonded with piezoelectric sensors and actuators is studied using the state-space method. The creep behavior of bonding adhesives between piezoelectric layers and beam is characterized by a Kelvin-Voigt viscoelastic model, which is practical in a high temperature circumstance. Both the host elastic functionally graded beam and the piezoelectric layers are orthotropic and in a state of plane stress, with the former being inhomogeneous along the thickness direction. A laminate model is employed to approximate the host beam. Moreover, the coupling effect between the elastic deformation and electric field in piezoelectric layers is considered. Results indicate that the viscoelastic property of interfacial adhesives has a significant effect on the function of bonded actuators and sensors with time elapsing.

关键词： functionally graded beam piezoelectric layers Kelvin-Voigt model state-space method