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World Journal of Gastroenterology 2024年第16期30卷 2209-2219页

作者： Na Cui Ting Dai Yang Liu Ya-yu Wang jia-yu lin Qing-Fan Zheng Dong-Dong Zhu Xue-Wei Zhu Department of Otorhinolaryngology Head and Neck Surgery China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of Ultrasound China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina Department of Gastroenterology China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina

Laryngopharyngeal reflux disease(LPRD)is an inflammatory condition in the laryngopharynx and upper aerodigestive tract mucosa caused by reflux of stomach contents beyond the *** commonly presents with symptoms such as hoarseness,cough,sore throat,a feeling of throat obstruction,excessive throat *** complex condition is thought to involve both reflux and reflex mechanisms,but a clear understanding of its molecular mechanisms is still ***,there is no standardized diagnosis or treatment *** strategies for LPRD mainly include lifestyle modifications,proton pump inhibitors and endoscopic *** paper seeks to provide a comprehensive overview of the existing literature regarding the mechanisms,pathophysiology and treatment of *** also provide an in-depth exploration of the association between LPRD and gastroesophageal reflux disease.

关键词： Laryngopharyngeal reflux Gastroesophageal reflux Head neck surgery Laryngitis Otolaryngology

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水电工程TBM洞挖料资源化利用对策与思考

水电能源科学 2024年第4期42卷 107-110页

作者：何佳龙喻葭临李祥何伟常作维水电水利规划设计总院北京100120

针对TBM洞挖料的综合利用率偏低、难以满足新形势下更高水平的绿色施工要求等问题,结合TBM洞挖料的材料特性及处理现状,分别从混凝土骨料、堆石坝筑坝材料及其他用途等方面开展了TBM洞挖料潜在利用方式的可行性讨论,提出了TBM洞挖料资... 详细信息

针对TBM洞挖料的综合利用率偏低、难以满足新形势下更高水平的绿色施工要求等问题,结合TBM洞挖料的材料特性及处理现状,分别从混凝土骨料、堆石坝筑坝材料及其他用途等方面开展了TBM洞挖料潜在利用方式的可行性讨论,提出了TBM洞挖料资源化利用需要关注的问题、常规处理手段及未来应用趋势,研究结果可为推动TBM洞挖料综合利用研究和创新实践方向提供参考。

关键词： TBM 洞挖料水电工程资源化利用绿色施工

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基于小样本学习融合随机深度和多尺度卷积的SDM-RNET网络

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计算机系统应用 2024年第4期33卷 93-102页

作者：刘馨瑶梁军余嘉琳华南师范大学软件学院佛山528225

针对神经网络难以利用少量标注数据获取足够的信息来正确分类图像的问题,提出了一种融合随机深度网络和多尺度卷积的关系网络——SDM-RNET.首先在模型嵌入模块引入随机深度网络用于加深模型深度,然后在特征提取阶段采用多尺度深度可分... 详细信息

针对神经网络难以利用少量标注数据获取足够的信息来正确分类图像的问题,提出了一种融合随机深度网络和多尺度卷积的关系网络——SDM-RNET.首先在模型嵌入模块引入随机深度网络用于加深模型深度,然后在特征提取阶段采用多尺度深度可分离卷积替代普通卷积进行特征融合,经过骨干网络后再采用深浅层特征融合获取更丰富的图像特征,最终学习预测出图像的类别.在mini-ImageNet、RP2K、Omniglot这3个数据集上对比该方法与其他小样本图像分类方法,结果表明在5-way 1-shot和5-way 5-shot分类任务上该方法准确率最高.

关键词：深度学习小样本学习图像分类

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鲜食糯玉米新品种辽糯5号的选育及栽培技术要点

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辽宁农业科学 2024年第2期 89-90页

作者：于惠琳吴玉群尤丹于佳霖张洋辽宁省农业科学院玉米研究所辽宁沈阳110161

辽糯5号是辽宁省农业科学院玉米研究所以自选系S15C08为母本、自选系YN1为父本组配而成的优质糯玉米杂交种。该品种具有熟期适中、果穗大小均匀、鲜穗外观好、品质优良、糯性强、柔嫩性好、稳产、抗病抗倒、适应性广等特点,2022年8月通... 详细信息

辽糯5号是辽宁省农业科学院玉米研究所以自选系S15C08为母本、自选系YN1为父本组配而成的优质糯玉米杂交种。该品种具有熟期适中、果穗大小均匀、鲜穗外观好、品质优良、糯性强、柔嫩性好、稳产、抗病抗倒、适应性广等特点,2022年8月通过辽宁省农作物品种审定委员会审定(辽审玉20220247)。

关键词：糯玉米辽糯5号选育栽培技术

Bradykinin postconditioning protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathway

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Neural Regeneration Research 2022年第10期17卷 2232-2237页

作者： Shi-Rong lin Qing-Ming lin yu-jia lin Xin Qian Xiao-Ping Wang Zheng Gong Feng Chen Bin Song Provincial College of Clinical Medicine Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Emergency Fujian Provincial Hospital South BranchFuzhouFujian ProvinceChina Department of Emergency Fujian Provincial HospitalFuzhouFujian ProvinceChina Fujian Emergency Medical Center FuzhouFujian ProvinceChina Fujian Provincial Key Laboratory of Emergency Medicine FuzhouFujian ProvinceChina Department of Human Anatomy School of Basic Medical SciencesFujian Medical UniversityFuzhouFujian ProvinceChina Key Laboratory of Brain Aging and Neurodegenerative Diseases of Fujian Province FuzhouFujian ProvinceChina Laboratory of Clinical Applied Anatomy Fujian Medical UniversityFuzhouFujian ProvinceChina

Bradykinin(BK)is an active component of the kallikrein-kinin system that has been shown to have cardioprotective and neuroprotective *** previously showed that BK postconditioning strongly protects rat hippocampal neurons upon restoration of spontaneous circulation(ROSC)after cardiac ***,the precise mechanism underlying this process remains poorly *** this study,we treated a rat model of ROSC after cardiac arrest(induced by asphyxiation)with 150μg/kg BK via intraperitoneal injection 48 hours after ROSC following cardiac *** found that BK postconditioning effectively promoted the recovery of rat neurological function after ROSC following cardiac arrest,increased the amount of autophagosomes in the hippocampal tissue,inhibited neuronal cell apoptosis,up-regulated the expression of autophagy-related proteins LC3 and NBR1 and down-regulated p62,inhibited the expression of the brain injury marker S100βand apoptosis-related protein caspase-3,and affected the expression of adenosine monophosphate-activated protein kinase/mechanistic target of rapamycin pathway-related *** monophosphate-activated protein kinase inhibitor compound C clearly inhibited BK-mediated activation of autophagy in rats after ROSC following cardiac arrest,which aggravated the injury caused by *** mechanistic target of rapamycin inhibitor rapamycin enhanced the protective effects of BK by stimulating *** findings suggest that BK postconditioning protects against injury caused by ROSC through activating the adenosine monophosphate-activated protein kinase/mechanistic target of the rapamycin pathway.

关键词： autophagy bradykinin cardiac arrest cardiopulmonary resuscitation compound C hippocampus neuron rapamycin restoration of spontaneous circulation

Successful treatment of eyebrow intradermal nevi by shearing combined with electrocautery and curettage:Two case reports

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世界临床病例杂志 2023年第27期11卷 6537-6542页

作者： Cheng Liu jia-Li Liang jia-lin yu Qun Hu Chang-Xing Li Department of Dermatology Guangdong Provincial Armed Police Corps HospitalGuangzhou 510507Guangdong ProvinceChina Department of Dermatology Nanfang HospitalSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of Dermatology Dalang HospitalDongguan 523770Guangdong ProvinceChina Department of Dermatology Southern Theater Command General HospitalGuangzhou 510010Guangdong ProvinceChina

BACKGROUND An intradermal nevus is a common skin tumour,and the classical method of removal has a risk of recurrence and *** is a challenge for dermatologists to treat eyebrow intradermal nevi quickly and *** study focused on investigating the efficacy and safety of shearing combined with electrocautery and curettage in the treatment of eyebrow intradermal *** SUMMARY We describe two adult patients with eyebrow intradermal nevi treated by shearing combined with electrocautery and *** patients were followed up regularly after *** follow-up,no recurrence of eyebrow intradermal nevus and no obvious scars or hypopigmentation were found in either *** results indicated that shearing combined with electrocautery and curettage could remove eyebrow intradermal nevus without side effects and confirmed the efficacy and safety of this modality for treating these skin *** Shearing combined with electrocautery and curettage has superior merits,including simple operation,good cosmetic effects,and high patient satisfaction,presenting great application potential for treating intracutaneous nevus.

关键词： Eyebrow Intradermal nevus Combined treatment Thermal diffusion Aesthetic surgery Case report

Incidence and prevalence levels of three aphid-transmitted viruses in crucifer crops in China

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Journal of Integrative Agriculture 2022年第3期21卷 774-780页

作者： ZHANG Xiao-yan PENG Yan-mei XIANG Hai-ying WANG Ying LI Da-wei yu jia-lin HAN Cheng-gui State Key Laboratory for Agrobiotechnology Ministry of Agriculture and Rural Affairs/Key Laboratory of Pest Monitoring and Green ManagementChina Agricultural UniversityBeijing 100193P.R.China College of Agriculture Ludong UniversityYantai 264025P.R.China

Poleroviruses,which are distributed worldwide,infect many crops of economic importance and cause severe plant *** yellows virus(Br YV),which has three genotypes,A,B,and C,is a newly identified polerovirus infecting crucifer crops in China,but its distribution is still ***,we report the distribution and prevalence levels of the three Br YV genotypes in crucifer crops in China.A total of 570 crucifer leaf samples randomly collected from 22 provinces,four ethnic minority autonomous regions,and three municipalities in China were tested for Br ***-PCR detection showed that 97 of the field samples were positive for Br YV,and the average incidence of Br YV was 17.0%.The virus was detected in 22 provinces,with high incidences in north,northwest,and northeast *** multiplex RT-PCR amplification of the three Br YV genotypes revealed that both single and mixed infections *** the Br YV infections,38.1% were mixinfected by more than two viral genotypes,and 8.2% samples were mix-infected by three viral *** findings indicated a widespread prevalence of Br YV in China,and Br YV mixed infections with Turnip mosaic virus and Cucumber mosaic virus in crucifer crops are *** study is the first large-scale survey of Br YV in crucifer crops in *** information generated in this investigation will contribute to the national prevention and control of viral diseases.

关键词： Brassica yellows virus three genotypes incidence crucifer crops

Lanthanum promoting bone formation by regulating osteogenesis,osteoclastogenesis and angiogenesis

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Journal of Rare Earths 2024年第3期42卷 621-628,I0007页

作者： Dandan Zou Runlian lin yu Han Juan jia Guoqiang Zhou Haisong Zhang Kun Ge Hebei Key Laboratory of Chronic Kidney Diseases and Bone Metabolism Affiliated Hospital of Hebei UniversityBaoding071000China Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education Key Laboratory of Chemical Biology of Hebei ProvinceCollege of Chemistry and Environmental ScienceHebei UniversityBaoding071002China

With lanthanum(La) in agriculture, medicine, and the chemical industry, La shows accumulation in the body, especially in the bone, because of its similar structure to calcium. Moreover, La has a direct role in bone formation regulating osteoblasts and osteoclasts. Nevertheless, bone formation is complex under the regulation of osteogenesis, osteoclastogenesis, and angiogenesis in the bone microenvironment. It is difficult to comprehensively understand the regulation of bone homeostasis from a single kind of ***, some bone microenvironment-related cells and mouse calvaria culture models were used to study the regulatory effect of La-based compound-lanthanum nitrate(La(NO_(3))_(3)) on bone ***(NO_(3))_(3) has good biological safety, and the osteogenic differentiation is significantly increased under La(NO_(3))_(3) treatment for bone marrow mesenchymal stem cells(BMMSC). In contrast, the differentiation,maturation, and bone erosion ability of osteoclasts are significantly decreased. Meanwhile, the angiogenesis ability of human umbilical vein endothelial cells(HUVEC) is significantly promoted when treated with La(NO_(3))_(3). Furthermore, bone metabolism and angiogenesis are improved under La(NO_(3))_(3) treatment in the calvaria ex vivo culture model and BMMSC-HUVEC co-culture system. These results suggest that La has the beneficial effect of promoting bone metabolism and improving bone formation in the bone microenvironment.

关键词： Lanthanum Bone microenvironment Osteogenic differentiation Angiogenesis Rare earths

LAMDA-SSL:a comprehensive semi-supervised learning toolkit

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Science China(Information Sciences) 2024年第1期67卷 306-307页

作者： lin-Han jia Lan-Zhe GUO Zhi ZHOU yu-Feng LI National Key Laboratory for Novel Software Technology Nanjing University

Machine learning, particularly deep learning, has achieved remarkable success across a wide range of tasks. However,most of these tasks demand a substantial amount of labeled training data, which can be challenging to obtain in many real-world applications due to difficulties, costs, or time constraints associated with labeling. In this context,semi-supervised learning (SSL) has emerged as a promising paradigm to alleviate the dependency on large labeled datasets by harnessing the power of unlabeled data [1–3].

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Design and Cryogenic Performance of a Hexapod Platform for a Large Ground-based Wide Field Survey Telescope

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Research in Astronomy and Astrophysics 2024年第1期24卷 178-187页

作者： Yang yu Xue-Wen Wang yu Zhang jia-lin Sun Zhen-Bang Xu jian-Li Wang Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Chinese Academy of Sciences Key Laboratory of On-orbit Manufacturing and Integration for Space Optics System Changchun 130033China University of Chinese Academy of Sciences Beijing 100049China

The thermal gradient is an important factor that causes degradation to the image quality of telescopes. In order to ensure the accurate alignment of the primary focus unit and the primary mirror, the hexapod platform(as a corrector) is investigated in this paper. First, a ground-based telescope with 2.5 m aperture and 3.5 deg field of view is described. The telescope is under construction, and it is expected to be finished in 2023. Second, the hexapod platform with flexure hinges utilized to adjust the primary focus unit is proposed, which is applied as a ***, the inverse kinematics of the platform is established and an open-loop control system is built based on ***, the cryogenic performance test for the hexapod platform is performed. The experimental results show that the resolution and repeatability of the translation for the hexapod platform can be achieved at the micrometer *** resolution and repeatability of the rotation can be achieved at the arc-second level. Therefore, the cryogenic performance of the hexapod platform can meet the optical imaging requirements of the wide-field ground-based telescope. The kinematic analysis and cryogenic performance tests in the paper provide a technical reference for the precise alignment of the primary focus unit and the primary mirror, which can improve the imaging quality of the telescope.

关键词： methods:miscellaneous space vehicles:instruments telescopes miscellaneous