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Smaller, faster, lower-power analog RRAM matrix computing circuits without performance compromise

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Science China(Information Sciences) 2025年

作者： Yubiao LUO Pushen ZUO Shiqing WANG Zhong sun Ru HUANG School of Integrated Circuits Peking University Institute for Artificial Intelligence Peking University Beijing Advanced Innovation Center for Integrated Circuits

Recently, the analog matrix computing (AMC) concept has been proposed for fast, efficient matrix operations, by configuring global feedback loops with crosspoint resistive memory arrays and operational amplifiers (OAs). The implementation of a general real-valued matrix (containing both positive and negative elements) is enabled by using a set of analog inverters,which, however, is considered inefficient regarding circuit compactness, power consumption, and temporal response. Here, with the assistance of the conductance compensation (CC) strategy to take full advantage of the inherent differential inputs of OAs,new AMC circuits without analog inverters are designed. Such a design saves the area occupation and power dissipation of analog inverters, and thus turns to be smaller and lower-power. Simulation results reveal that the new circuit also shows a faster response towards the steady state, thanks to the reduction of poles in the circuit, which, again, is contributed by the elimination of analog inverters. Along with all of these benefits, extensive simulations demonstrate that the CC-AMC circuits do not compromise the computing performance in terms of relative error caused by various non-ideal factors in the circuit.

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Microstructure and evolution of hafnium carbide whiskers via polymer-derived ceramics:A novel formation mechanism

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Journal of Advanced Ceramics 2023年第3期12卷 578-586页

作者： Yanqin Fu Yulei Zhang Hao Yan Jinhua Li Xuemin yin jia sun Qiangang Fu Ralf Riedel Shaanxi Key Laboratory of Fiber Reinforced Light Composite Materials Northwestern Polytechnical UniversityXi’an 710072China School of Materials and Chemical Engineering Xi’an Technological UniversityXi’an 710021China Institut für Materialwissenschaft Technische Universität DarmstadtDarmstadt D-64287Germany

Polymer-derived ultra-high-temperature ceramic(UHTC)nanocomposites have attracted growing attention due to the increasing demands for advanced thermal structure components in ***,hafnium carbide(HfC)whiskers are successfully fabricated in carbon fiber preforms via the polymer-derived ceramic(PDC)method.A novel carbon nanotube(CNT)template growth mechanism combined with the PDC method is proposed in this work,which is different from the conventional vapor–liquid–solid(VLS)mechanism that is commonly used for polymer-derived nanostructured *** CNTs are synthesized and proved to be the templates for fabricating the HfC whiskers,which are generated by the released low-molecular-weight gas such as CO,CO_(2),and CH4 during the pyrolysis of a Hf-containing *** formed products are composed of inner single crystal HfC whiskers that are measured to be several tens of micrometers in length and 100–200 nm in diameter and outer HfC/HfO_(2)*** work not only proposes a new strategy to prepare the HfC whiskers,but also puts forward a new thinking of the efficient utilization of a UHTC polymer precursor.

关键词： HfC whiskers carbon nanotubes(CNTs) CNT template Hf-containing precursor thermal pyrolysis

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

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Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-Yan sun Lingyun Nie Jing Zhang Xue Fang Hongmei Luo Chuanhai Fu Zhiyi Wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

Electrode/Electrolyte Optimization‑Induced Double‑Layered Architecture for High‑Performance Aqueous Zinc‑(Dual)Halogen Batteries

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Nano-Micro Letters 2025年第3期17卷 121-137页

作者： Chengwang Zhou Zhezheng Ding Shengzhe ying Hao jiang Yan Wang Timing Fang You Zhang Bing sun Xiao Tang Xiaomin Liu School of Textiles and Clothing School of Chemistry and Chemical EngineeringQingdao UniversityQingdao 266071ShandongPeople’s Republic of China Centre for Clean Energy Technology School of Mathematical and Physical SciencesFaculty of ScienceUniversity of Technology SydneyUltimoNSW 2007Australia School of Chemistry and Chemical Engineering Henan Normal UniversityXinxiang 453007HenanPeople’s Republic of China

Aqueous zinc-halogen batteries are promising candidates for large-scale energy storage due to their abundant resources,intrinsic safety,and high theoretical ***,the uncontrollable zinc dendrite growth and spontaneous shuttle effect of active species have prohibited their practical ***,a double-layered protective film based on zinc-ethylenediamine tetramethylene phosphonic acid(ZEA)artificial film and ZnF2-rich solid electrolyte interphase(SEI)layer has been successfully fabricated on the zinc metal anode via electrode/electrolyte synergistic *** ZEA-based artificial film shows strong affinity for the ZnF2-rich SEI layer,therefore effectively suppressing the SEI breakage and facilitating the construction of double-layered protective film on the zinc metal *** double-layered architecture not only modulates Zn2+flux and suppresses the zinc dendrite growth,but also blocks the direct contact between the metal anode and electrolyte,thus mitigating the corrosion from the active *** employing optimized metal anodes and electrolytes,the as-developed zinc-(dual)halogen batteries present high areal capacity and satisfactory cycling *** work provides a new avenue for developing aqueous zinc-(dual)halogen batteries.

关键词： Zn metal anodes Double-layered protective film Electrode/electrolyte optimization Aqueous zinc-(dual)halogen batteries

ReSSIM:a mixed-level simulator for dynamic coarse-grained reconfigurable processor

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Science China(Information Sciences) 2013年第6期56卷 137-152页

作者： LIU LeiBo jia Wen yin ShouYi WANG Dong sun GuanYi TANG Eugene WEI ShaoJun Institute of Microelectronics and National Laboratory for Information Science and Technology Tsinghua University Intel China Research Center

This paper proposes a mixed-level simulator for dynamic coarse-grained reconfigurable processor(CGRP),called ReSSIM(reconfigurable system simulation implementation mechanism),and the corresponding simulation tool-chain,including task compiler,profiler and debugger.A generic modeling methodology supporting convenient extension of on-chip modules is also *** order to explore the details of the interested modules while maintaining reasonable simulation speed,RCA(reconfigurable computing array),the key reconfigurable device in ReSSIM,is modeled on cycle-accurate level,while the other modules are modeled on transaction *** typical parameters of RCA are scalable and adjustable,which helps the architects to explore the massive details of the reconfigurable *** shows that simulation speedup achieved ranges from 9.26× to 18.39× compared with VCS(Synopsys verilog compiler simulator) when running three computingintensive kernel tasks of H.264 decoding algorithm-IDCT(inverse discrete cosine transform),deblocking and MC-chroma(motion compensation).Simulation speed for a set of real applications,such as MPEG4,G.729 and EFR,is 35× slower than the corresponding native executions(*** from the real chip).And the relative simulation errors are 11% less than the measured IPC(instructions per cycle) of the real chip.

关键词： CGRP RCA ReSSIM modeling simulator

Neuroprotective potential for mitigating ischemia-reperfusion-induced damage

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Neural Regeneration Research 2025年第8期20卷 2199-2217页

作者： Zi Ye Runqing Liu Hangxing Wang Aizhen Zuo Cen Jin Nan Wang Huiqi sun Luqian Feng Hua Yang The Clinical Medical College Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Infectious Diseases Department of Internal MedicinePeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina School of Medical Imaging Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Gastroenterology First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina The Second Clinical Medical College Lanzhou UniversityLanzhouGansu ProvinceChina Department of Neurosurgery Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhou ProvinceChina

Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient's condition;this phenomenon is known as cerebral ischemia-reperfusion *** studies have elucidated the neuroprotective role of the sirtuin protein family(Sirtuins)in modulating cerebral ischemia-reperfusion ***,the potential of utilizing it as a novel intervention target to influence the prognosis of cerebral ischemia-reperfusion injury requires additional *** this review,the origin and research progress of Sirtuins are summarized,suggesting the involvement of Sirtuins in diverse mechanisms that affect cerebral ischemia-reperfusion injury,including inflammation,oxidative stress,blood-brain barrier damage,apoptosis,pyroptosis,and *** therapeutic avenues related to Sirtuins that may improve the prognosis of cerebral ischemia-reperfusion injury were also investigated by modulating Sirtuins expression and affecting representative pathways,such as nuclear factor-kappa B signaling,oxidative stress mediated by adenosine monophosphate-activated protein kinase,and the forkhead box *** review also summarizes the potential of endogenous substances,such as RNA and hormones,drugs,dietary supplements,and emerging therapies that regulate Sirtuins *** review also reveals that regulating Sirtuins mitigates cerebral ischemia-reperfusion injury when combined with other risk *** Sirtuins show promise as a potential target for the treatment of cerebral ischemiareperfusion injury,most recent studies are based on rodent models with circadian rhythms that are distinct from those of humans,potentially influencing the efficacy of Sirtuinstargeting drug ***,this review provides new insights into the role of Sirtuins in the pathology and treatment of cerebral ischemia-reperfusion injury.

关键词： apoptosis autophagy blood-brain barrier dietary supplements drug hormones inflammation neuroprotection oxidative stress prognosis pyroptosis reperfusion injury risk factors RNA therapeutics

RepColor: deep coloring algorithm combining semantic categories

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Optoelectronics Letters 2025年

作者： Lei sun Dongjie Ju School of Electrical Engineering and Automation， Tianjin University of Technology Tianjin Key Laboratory for Control Theory and Complicated Industry Systems， Tianjin University of Technology

Image coloring is an inherently uncertain and multimodal problem. By inputting a grayscale image into a coloring network， visually plausible colored photos can be generated. Conventional methods primarily rely on semantic information for image colorization. Although effective in coloring images with clear semantic information， these methods still suffer from color contamination and semantic confusion. This is largely due to the limited capacity of convolutional neural networks to effectively learn deep semantic information inherent in *** this paper， we propose a network structure that addresses these limitations by leveraging multi-level semantic information classification and fusion. Additionally， we introduce a global semantic fusion network to combat the issues of color contamination. The proposed coloring encoder accurately extracts object-level semantic information from *** further enhance visual plausibility， we employ a self-supervised adversarial training method. We train the network structure on various datasets with varying amounts of data and evaluate its performance using the ImageNet validation set and COCO validation set. Experimental results demonstrate that our proposed RepColor can generate more realistic images compared to previous approaches， showcasing its high generalization ability.

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Plasmonic tandem heterojunctions enable high-efficiency charge transfer for broad spectrum photocatalytic hydrogen production

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Journal of Energy Chemistry 2025年第1期100卷 710-720页

作者： Wenxuan Chen Xiu-Qing Qiao Guo Hui Bojing sun Dongfang Hou Meidi Wang Xueqian Wu Tao Wu Dong-Sheng Li College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials China Three Gorges University Hubei Three Gorges Laboratory College of Chemistry and Materials Science and Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry Jinan University

Rational engineering of semiconductor photocatalysts for efficient hydrogen production is of great significance but still challenging,primarily due to the limitations in charge transfer ***,a fascinating plasmonic tandem heterojunction with the hc-CdS/Mo2C@C heterostructure is aimfully prepared for effectively promoting the charge separation kinetics of the CdS photocatalyst via the synergistic strategy of phase junction,Schottky junction,and photothermal *** difference in atomic configuration between cubic-CdS （c-CdS） and hexagonal-CdS （h-CdS） leads to effective charge separation through a typical Ⅱ charge transfer mechanism,and plasmonic Schottky junction further extracts the electrons in the hc-CdS phase junction to realize gradient charge ***,the photothermal effect of Mo2C@C helps to expand the light absorption,accelerate charge transfer kinetics,and reduce the hydrogen evolution energy *** carbon layer provides a fast channel for charge transfer and protects the photocatalyst from *** a result,the optimized hc-CMC photocatalyst exhibits a significantly high photocatalytic H2production activity of 28.63 mmol/g/h and apparent quantum efficiency of 61.8%,surpassing most of the reported *** study provides a feasible strategy to enhance the charge transfer kinetics and photocatalytic activity of CdS by constructing plasmonic tandem heterogeneous junctions.

关键词： Cadmium sulfide

Facile synthesis of suvorexant,an orexin receptor antagonist,via a chiral diazepane intermediate

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Chinese Chemical Letters 2015年第1期26卷 103-107页

作者： yin Chen Yan Zhou Jun-Hong Li jia-Quan sun Gui-Sen Zhang Systems Biology Theme Department of Biomedical EngineeringCollege of Life Science and TechnologyHuazhong University of Science and Technology jiangsu Nhwa Pharmaceutical Co. Ltd.

A facile synthesis of suvorexant, an orexin receptor antagonist, is described. The key intermediate 6 was prepared from R-3-aminobutyric acid through protection, condensation, deprotection, cyclization, and hydrogenation steps. The title product was obtained with a total yield of 31% （〉99% ee） after eight linear steps using commercially available raw materials.

关键词： Synthesis Suvorexant Chiral diazepane