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绿原酸防龋的实验研究

广东药学院学报 2012年第5期28卷 549-551页

作者：林家成赵玮卢佳璇中山大学光华口腔医学院.附属口腔医院/广东省口腔医学重点实验室广东广州510055

目的研究绿原酸对龋病发生发展的抑制效果。方法制备不同浓度绿原酸,采用液体稀释法检测其体外抑制变形链球菌和远缘链球菌的效果;建立SD大鼠人工龋模型,分别用绿原酸溶液、甲硝唑洗必泰溶液和蒸馏水给大鼠施药,采用Keyes记分法观察绿... 详细信息

目的研究绿原酸对龋病发生发展的抑制效果。方法制备不同浓度绿原酸,采用液体稀释法检测其体外抑制变形链球菌和远缘链球菌的效果;建立SD大鼠人工龋模型,分别用绿原酸溶液、甲硝唑洗必泰溶液和蒸馏水给大鼠施药,采用Keyes记分法观察绿原酸对大鼠口腔内龋齿发生发展的抑制效果。结果绿原酸溶液对变形链球菌ATCC10449株和远缘链球菌OMZ65株的最小抑菌浓度均为2.5 mg/mL,最小杀菌浓度分别为7.5 mg/mL和5 mg/mL。在人工龋大鼠模型中,与蒸馏水相比,绿原酸组龋齿计分明显降低,而与甲硝唑洗必泰组相近。结论绿原酸对变形链球菌和远缘链球菌生长有明显抑制作用,并可有效抑制大鼠龋齿的发生发展。

关键词：绿原酸变形链球菌 SD大鼠龋病

“Zero‑Strain” NiNb_(2)O_(6) Fibers for All‑Climate Lithium Storage

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Nano-Micro Letters 2025年第1期17卷 348-360页

作者： Yan Zhao Qiang Yuan Liting Yang Guisheng Liang Yifeng cheng Limin Wu Chunfu lin Renchao Che College of Physics Donghua UniversityShanghai 201620People’s Republic of China School of Materials Science and Engineering Institute of Materials for Energy and EnvironmentQingdao UniversityQingdao 266071People’s Republic of China Laboratory of Advanced Materials Shanghai Key Laboratory of Molecular Catalysis and Innovative MaterialsAcademy for Engineering&TechnologyFudan UniversityShanghai 200438People’s Republic of China Zhejiang Laboratory Hangzhou 311100People’s Republic of China Inner Mongolia University Hohhot 010021People’s Republic of China

Niobates are promising all-climate Li^(+)-storage anode material due to their fast charge transport,large specific capacities,and resistance to electrolyte ***,their moderate unit-cellvolume expansion(generally 5%–10%)during Li^(+)storage causes unsatisfactory long-term ***,“zero-strain”NiNb_(2)O_(6) fibers are explored as a new anode material with comprehensively good electrochemical *** Li^(+)storage,the expansion of electrochemical inactive NiO_(6) octahedra almost fully offsets the shrinkage of active NbO_(6) octahedra through reversible O *** superior volume-accommodation capability of the NiO_(6) layers guarantees the“zero-strain”behavior of NiNb_(2)O_(6) in a broad temperature range(0.53%//0.51%//0.74%at 25//−10//60℃),leading to the excellent cyclability of the NiNb_(2)O_(6) fibers(92.8%//99.2%//91.1%capacity retention after 1000//2000//1000 cycles at 10C and 25//−10//60℃).This NiNb_(2)O_(6) material further exhibits a large reversible capacity(300//184//318 mAh g−1 at 0.1C and 25//−10//60℃)and outstanding rate performance(10 to 0.5C capacity percentage of 64.3%//50.0%//65.4%at 25//−10//60℃).Therefore,the NiNb_(2)O_(6) fibers are especially suitable for large-capacity,fast-charging,long-life,and all-climate lithium-ion batteries.

关键词： NiNb_(2)O_(6)porous fiber “Zero-strain”mechanism Electrochemical property Harsh-temperature operation Operando characterization

Rapid Detection of wheat yellow mosaic virus by Reverse Transcription Loop-mediated Isothermal Amplification

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Rapid Detection of wheat yellow mosaic virus by Reverse Tran...

Primary parenchymal squamous cell carcinoma of the kidney:A case report

中国植物病理学会2011年学术年会

作者： Zhang Zong-ying,Liu Xiao-jun,Li Da-wei,Yu jia-lin,Han cheng-gui (Department of Plant Pathology and State Key Laboratory for Agrobiotechnology, China Agricultural University,Beijing 100193,P.R.China)

＜正＞For the detection of Wheat yellow mosaic virus（WYMV）,a reverse transcription loop-mediated isothermal amplification（RT-LAMP） method was *** Primer Explorer software,four sets of primers were designed to carry out RT-LAMP for WYMV *** sets of primers were *** set IV primers were chosen randomly for developing the specificity and sensitivity of RT-LAMP for WYMV,and detecting WYMV for the field *** specificity test indicated that the WYMV primers could amplify WYMV but not Chinese wheat mosaic virus and barley stripe mosaic virus ***

关键词： wheat yellow mosaic virus reverse transcription

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World Journal of Clinical Cases 2025年第4期13卷 34-40页

作者： Zhi-Hui Zheng Bo Shao Chao-Min Xu Ke Wang jia-Zhu Wen Li-Kang Luo jia-cheng Guan Department of Ultrasound The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Radiology Shulan(Quzhou)HospitalQuzhou 324000Zhejiang ProvinceChina Department of Radiology The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Pathology The Second people’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina

BACKGROUND Primary squamous cell carcinoma(SCC)of the renal parenchyma is extremely rare,with only nine cases *** SUMMARY This study reports a 51-year-old man with primary SCC of the renal *** patient was admitted with recurrent dull pain and discomfort in the right lumbar region,which had worsened over 2 weeks,accompanied by painful gross *** antigen(SCCA)levels were elevated,and imaging revealed a renal mass with associated *** patient underwent laparoscopic unilateral nephrectomy and lymph node *** pathology confirmed highly differentiated SCC with necrosis in the right renal parenchyma,with negative renal pelvis and *** pathological stage was *** months after surgery,the tumor recurred with involvement of the liver,right psoas major muscle,and inferior vena *** patient refused chemotherapy and succumbed to the disease 6 months postoperatively due to disease *** We report a case of primary SCC of the renal parenchyma,a rare renal *** clinical symptoms,laboratory tests,and imaging findings are nonspecific,making accurate and timely diagnosis *** to the literature,for patients with renal calculi accompanied by a renal mass,elevated serum SCCA levels,and magnetic resonance imaging showing cystic or cystic-solid masses within the kidney with pseudocapsules and heterogeneous mild enhancement,the possibility of this disease should be considered.

关键词： Renal tumor Renal parenchyma Squamous cell carcinoma Renal calculi Computed tomography Case report

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关于故障录波装置PT断线告警逻辑的优化

电工电气 2016年第8期 33-35页

作者：林家成王宇鹏南方电网超高压输电公司柳州局广西柳州545006

现有故障录波装置的PT断线逻辑只有在某一相或两相有压而剩余其他相无压时报PT断线告警,当出现空开脱扣或电缆并接处断开等情况会造成三相电压实时数据丢失,则录波装置不发出PT断线告警。提出一种优化的录波装置PT断线告警的逻辑,该方... 详细信息

现有故障录波装置的PT断线逻辑只有在某一相或两相有压而剩余其他相无压时报PT断线告警,当出现空开脱扣或电缆并接处断开等情况会造成三相电压实时数据丢失,则录波装置不发出PT断线告警。提出一种优化的录波装置PT断线告警的逻辑,该方案通过引入各种辅助判据量对原有逻辑进行优化,从而消除记录盲区,使运维人员及时发现并处理录波装置所采电压量的异常。

关键词：故障录波 PT断线告警优化逻辑

Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation

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World Journal of Gastroenterology 2025年第1期31卷 58-67页

作者： Mu-Hsien Lee cheng-Hui lin Chi-Huan Wu Yung-Kuan Tsou Kai-Feng Sung Sheng-Fu Wang Nai-Jen Liu Department of Gastroenterology and Hepatology Chang Gung Memorial Hospital and Chang Gung University College of MedicineTaoyuan 33305Taiwan School of Medicine Chang Gung UniversityTaoyuan 33305Taiwan

BACKGROUND Needle-knife precut papillotomy(NKP)is typically performed ***,it remains unclear whether pancreatic stent(PS)placement can improve the outcomes of *** To explore whether PS placement improves the success rate of NKP in patients with difficult biliary *** This single-center retrospective study included 190 patients who underwent NKP between January 2017 and December 2021 after failed conventional biliary *** cases with incidental pancreatic duct cannulation during conventional biliary cannulation,the decision for pre-NKP PS placement was made at the endoscopist's *** primary outcome was the difference in the NKP success rate between patients with and without PS placement;the secondary outcome was the adverse event *** Among the 190 participants,82 received pre-NKP PS(PS-NKP group)whereas 108 did not[freehand or freehand NKP(FH-NKP)group].Post-NKP selective biliary cannulation was successful in 167(87.9%)patients,and the PS-NKP had a significantly higher success rate than the FH-NKP group(93.9%vs 83.3%,P=0.027).The overall adverse event rates were 7.3%and 11.1%in the PS-NKP and FH-NKP groups,respectively(P=0.493).A periampullary diverticulum(PAD)and significant intraoperative bleeding during NKP were independently associated with NKP failure;however,a pre-NKP PS was the only predictor of NKP *** the 44 participants with PADs,the PS-NKP group had a non-significantly higher NKP success rate than the FH-NKP group(87.5%and 65%,respectively;P=0.076).CONCLUSION PS significantly improved the success rate of NKP in patients with difficult biliary cannulation.

关键词： Difficult biliary cannulation Endoscopic retrograde cholangiopancreatography Needle-knife papillotomy Pancreatic stent Selective biliary cannulation

氟化漆氯已定凝胶联合应用降低SECC患儿龋齿复发率的疗效观察

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牙体牙髓牙周病学杂志 2015年第2期25卷 107-109,103页

作者：林家成赵玮凌均棨中山大学光华口腔医学院.附属口腔医院.广东省口腔医学重点实验室广东广州510055

目的:评估氟化漆氯已定凝胶联合作用降低重度早期儿童龋(SECC)复发率的临床效果。方法:选择SECC患儿100名,随机分为2组(n=50),实验组采用氟化漆与氯已定凝胶联合作用的方法,对照组则不使用任何药物;比较两组SECC复发率变化情况。结果:S... 详细信息

目的:评估氟化漆氯已定凝胶联合作用降低重度早期儿童龋(SECC)复发率的临床效果。方法:选择SECC患儿100名,随机分为2组(n=50),实验组采用氟化漆与氯已定凝胶联合作用的方法,对照组则不使用任何药物;比较两组SECC复发率变化情况。结果:SECC累计复发率在6个月时,实验组和对照组分别为6.12%和25.58%;12个月时,实验组和对照组分别为13.04%和33.33%;18个月时,实验组和对照组分别为21.95%和57.50%;2年时,实验组和对照组分别为32.50%和72.22%;各时间点两组SECC累计复发率相比均有统计学差异(P<0.05)。结论:采用氟化漆与氯已定凝胶联合作用的方法可有效降低SECC复发率。

关键词：重度早期儿童龋复发氟化漆氯已定凝胶

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中医药保护高血压内皮功能的研究进展

上海中医药杂志 2016年第8期50卷 94-97页

作者：贾成林陈瑜张腾上海中医药大学附属岳阳中西医结合医院上海200437 上海市中医药研究院中西医结合临床研究所上海200437

综述中医药保护高血压内皮功能的研究进展。从炎症、氧化应激、免疫系统、肾素-血管紧张素-醛固酮系统、同型半胱氨酸、内皮微颗粒等多个方面阐述内皮功能紊乱在高血压发生发展过程中的作用,中医药对高血压内皮功能的保护起到了重要作用。

关键词：高血压中医药疗法内皮功能紊乱综述

中医药对高血压前期干预效应及其作用机制研究进展

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中医药信息 2013年第3期30卷 156-160页

作者：贾成林陈瑜张腾上海中医药大学附属岳阳中西医结合医院上海200437 上海中医药大学附属岳阳医院中西医结合临床研究所上海200437

原发性高血压是心脏病、终末期肾病、脑血管疾病、中风等的最常见的危险因素之一。一直以来在高血压的发生机制、预防、治疗等多方面做了诸多努力,但高血压的发病率仍居高不下,甚至呈现上升趋势。因此,早期预防、早期治疗引起了全球公... 详细信息

原发性高血压是心脏病、终末期肾病、脑血管疾病、中风等的最常见的危险因素之一。一直以来在高血压的发生机制、预防、治疗等多方面做了诸多努力,但高血压的发病率仍居高不下,甚至呈现上升趋势。因此,早期预防、早期治疗引起了全球公共卫生的重视,中医药对高血压及高血压前期的认识及治疗有着其独特的优势。就近年来中医药对高血压前期干预效应及其作用机制的研究成果及存在的问题进行综述,以供同道参阅。

关键词：高血压前期中医药机制