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Application of Tranexamic Acid in Shoulder Arthroscopic Surgery:A Randomised Controlled Trial

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Chinese Medical Sciences Journal 2023年第4期38卷 273-278页

作者： Tian-Ci Wang jia-liang Guo Qiu-Ping Tian He-Ping Deng Bing Yin Zeng Xiao Bo Lu Department of Orthopedic Trauma Hebei Medical University Third Affiliated HospitalShijiazhuang 050051China Medical Services Section Hebei Medical University Third Affiliated HospitalShijiazhuang 050051China Department of Ultrasonography Hebei Medical University Third Affiliated HospitalShijiazhuang 050051China Graduate School of Hebei Medical University Shijiazhuang 050011China

Objective To explore the optimal administration route of tranexamic acid(TXA)in shoulder arthroscopic *** Patients undergoing arthroscopic rotator cuff repair were randomly divided into four groups:control group(without TXA treatment),intravenous group(TXA was intravenously administered 10 minutes before surgery),irrigation group(TXA was added to the irrigation fluid during subacromial decompression and acromioplasty),and intravenous plus irrigation group(TXA was applied both intravenously and via intra-articular irrigation).The primary outcome was visual clarity assessed with visual analog scale(VAS)score,and the secondary outcomes included irrigation fluid consumption and time to subacromial decompression and acromioplasty *** There were 134 patients enrolled in the study,including 33 in the control group,35 in the intravenous group,32 in the irrigation group,and 34 in the intravenous plus irrigation *** median and interquartile range of VAS scores for the intravenous,irrigation,and intravenous plus irrigation groups were 2.70(2.50,2.86)(Z=-3.677,P=0.002),2.67(2.50,2.77)(Z=-3.058,P<0.001),and 2.91(2.75,3.00)(Z=-6.634,P<0.001),respectively,significantly higher than that of the control group[2.44(2.37,2.53)].Moreover,the control group consumed more irrigation fluid than the intravenous group,irrigation group,and intravenous plus irrigation group(all P<0.05).The intravenous plus irrigation group consumed less irrigation fluid than either the intravenous group or the irrigation group(both P<0.001).There was no difference in subacromial decompression and acromioplasty operative time among the four *** TXA applied both topically and systematically can improve intraoperative visual clarity,and the combined application is more effective.

关键词： tranexamic acid shoulder arthroscopic surgery visual clarity rotator cuff tear administration route

Glymphatic function and its influencing factors in different glucose metabolism states

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World Journal of Diabetes 2024年第7期15卷 1537-1550页

作者： Bin Tian Chen Zhao jia-Li liang Hui-Ting Zhang Yi-Fan Xu Hui-Lei Zheng jia Zhou jiang-Nian Gong Shu-Ting Lu Zi-San Zeng Department of Radiology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Magnetic Resonance Research Collaboration Siemens HealthineersGuangzhou 510620Guangdong ProvinceChina Magnetic Resonance Research Collaboration Siemens Healthineers Ltd.Wuhan 430071Hubei ProvinceChina Department of Health Management The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Endocrinology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina

BACKGROUND Dysfunction of the glymphatic system in the brain in different stages of altered glucose metabolism and its influencing factors are not well *** To investigate the function of the glymphatic system and its clinical correlates in patients with different glucose metabolism states,the present study employed diffusion tensor imaging along the perivascular space(DTI-ALPS)*** Sample size was calculated using the pwr package in R *** crosssectional study enrolled 22 patients with normal glucose metabolism(NGM),20 patients with prediabetes,and 22 patients with type 2 diabetes mellitus(T2DM).A 3.0T magnetic resonance imaging was used to evaluate the function of the glymphatic *** mini-mental state examination(MMSE)was used to assess general cognitive *** DTI-ALPS index of bilateral basal ganglia and the mean DTI-ALPS index was ***,the correlation between DTI-ALPS and clinical features was *** The left-side,right-side,and mean DTI-ALPS index in the T2DM group were significantly lower than that in the NGM *** right-side DTI-ALPS and mean DTI-ALPS index in the T2DM group were significantly lower than those in the prediabetes ***-ALPS index lateralization was not *** MMSE score in the T2DM group was significantly lower than that in the NGM and prediabetes *** controlling for sex,the left-side DTI-ALPS and mean DTI-ALPS index in the prediabetes group were positively correlated with 2-hour postprandial blood glucose level;the left-side DTI-ALPS index was negatively correlated with total cholesterol and low-density lipoprotein *** right-side DTI-ALPS and mean DTI-ALPS index were negatively correlated with the glycosylated hemoglobin level and waist-to-hip ratio in the prediabetes *** left-side,right-side,and mean DTI-ALPS index in the T2DM group were positively correlated with *** left-side and mean DTIALPS index in the T2DM group were negatively

关键词： Glymphatic system Prediabetes Type 2 diabetes mellitus Magnetic resonance imaging Diffusion tensor imaging along the perivascular space

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当前冠心病介入治疗中应认真审视的问题

中华心血管病杂志 2005年第3期33卷 201-203页

作者：贾国良第四军医大学附属西京医院心血管病研究所内科中心西安710032

随着经皮冠状动脉介入治疗(PCI)新器材的问世、品质的改进及术者经验的积累,早期很多禁忌证和相对禁忌证现已成为PCI的适应证.特别是近年来药物涂层支架的临床应用,左主干(LMCA)病变、分叉部病变、长的弥漫性病变、慢性闭塞性病变以及... 详细信息

随着经皮冠状动脉介入治疗(PCI)新器材的问世、品质的改进及术者经验的积累,早期很多禁忌证和相对禁忌证现已成为PCI的适应证.特别是近年来药物涂层支架的临床应用,左主干(LMCA)病变、分叉部病变、长的弥漫性病变、慢性闭塞性病变以及糖尿病伴多支病变的PCI都已成为热点.因此,正确认识PCI在冠心病治疗中的地位,使之健康、正常的发展是当前极应重视的问题。

关键词：冠心病临床应用介入治疗 PCI 病变药物涂层支架治疗中积累分叉

Improved mechanical and wear properties of Ti-35Nb-5Ta-7Zr-xSi alloys fabricated by selective electron beam melting for biomedical application

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Journal of Central South University 2022年第12期29卷 3825-3835页

作者： YANG Kun WANG jian YANG Guang-yu jia liang College of Materials Science and Engineering Jilin UniversityChangchun 130025China State Key Laboratory of Porous Metal Materials(Northwest Institute for Nonferrous Metal Research) Xi’an 710016China

As the next generation biomedical titanium alloy, β-type titanium alloys are excellent candidates for biomedical applications due to the relative low elastic modulus and the contained non-toxic elements. However, the relative low strength and unsatisfactory tribological property are undesired for load-bearing implant applications. In this study, 0-5 at% Si was added to the classic Ti-35Nb-5Ta-7Zr alloy to improve its strength and wear resistance, and the(Ti-35Nb-5Ta-7Zr)1-x-Six(x=0, 1 at% and 5 at%) alloy were fabricated by selective electron beam melting(SEBM)technology. The results indicated that Si addition significantly increases in compressive yield strength, which is mainly due to grain refinement strengthening. At the same time, the wear rate of the as-built TNTZ-5Si alloy in SBF solution was only ~30% of the Ti-6Al-4V alloy. Consequently, the TNTZ-5Si alloy showed an excellent combination of compressive yield strength, elastic modulus and wear resistance for potential load-bearing implant applications.

关键词： β-type titanium alloys additive manufacturing microstructure mechanical properties wear resistance

Softev: UML-Based PSEE Environment

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Wuhan University Journal of Natural Sciences 2001年第Z1期6卷 524-530页

作者： Pan Qiu ling, Liu Zong tian, jia liang, Xiu Qing,Pan Biao Research Institute of Microcomputer, Hefei University of Technology, Hefei 230009, China Research Institute of Microcomputer Hefei University of Technology Hefei 230009 China

Software development processes, as a mean to ensure software quality and productivity, have been widely accepted within the software development community. This research introduces how to assist developers to establish quality management plan and monitor the implementation of software processes quantitatively in a CASE environment. A PSEE (process centered software engineering environment) named Softev has been brought forward to provide developers the environment to define, execute and monitor their processes. As UML is becoming a standard diagrammatic notation for object oriented modeling and is spreading rapidly, it has been chosen to express the artifacts developed during the requirement analysis and system design stages. In the early products of software process engineering, most research mainly focus on the representations of complex organizational processes and architectures for process centered application support environment. However, the metrics of software processes and artifacts was not paid sufficient attention to. This research proposes the attributes to be measured during the development period which enable managers to predict and supervise the software project more precisely.

关键词： software process quality control UML metrics

Vague等价关系与Vague划分之间的关系研究

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电子与信息学报 2010年第4期32卷 1008-1011页

作者：梁家荣广西大学计算机与电子信息学院南宁530004

根据vague集具有真假隶属度的特点,该文提出了基于t-模和t-余模的(T,S)-vague等价关系和t-模对界定的概念。建立了(T,S)-vague等价关系与(T,S)-vague划分之间的一一对应关系。通过引进(T,S)-vague划分的(T*,S*)交的概念,给出了X上任何两... 详细信息

根据vague集具有真假隶属度的特点,该文提出了基于t-模和t-余模的(T,S)-vague等价关系和t-模对界定的概念。建立了(T,S)-vague等价关系与(T,S)-vague划分之间的一一对应关系。通过引进(T,S)-vague划分的(T*,S*)交的概念,给出了X上任何两个(T,S)-vague划分的(T*,S*)交仍然是一个(T,S)-vague划分的充要条件。

关键词：信息处理 t-模 t-余模 Vague等价关系 Vague划分

基于优化堆叠降噪自编码器的滚动轴承故障诊断

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吉林大学学报（工学版） 2022年第12期52卷 2827-2838页

作者：杜先君贾亮亮兰州理工大学电气工程与信息工程学院兰州730050 兰州理工大学甘肃省工业过程先进控制重点实验室兰州730050 兰州理工大学国家级电气与控制工程实验教学中心兰州730050

针对深度神经网络用于滚动轴承故障诊断时,网络隐含层层数、各隐含层节点数、稀疏系数以及输入数据置零比例等超参数会直接影响网络诊断性能的问题,提出了一种优化改进堆叠降噪自编码器(SDAE)的滚动轴承故障智能诊断方法。使用学生心理... 详细信息

针对深度神经网络用于滚动轴承故障诊断时,网络隐含层层数、各隐含层节点数、稀疏系数以及输入数据置零比例等超参数会直接影响网络诊断性能的问题,提出了一种优化改进堆叠降噪自编码器(SDAE)的滚动轴承故障智能诊断方法。使用学生心理优化算法(SPBO)对降噪自编码器(DAE)网络的超参数进行自适应选取来确定SDAE网络的最优结构和参数,据此提取具有更强表征力的故障状态特征表示,输入到soft-max分类器实现滚动轴承运行工况的精确诊断。使用3个开源数据集对所提网络的性能进行验证,实验结果表明,基于SPBO-SDAE网络的诊断方法在特征有效提取、诊断速度以及故障诊断准确率方面均优于支持向量机(SVM)、反向传播(BP)神经网络、径向基(RBF)神经网络、SDAE网络、SPBO优化后的深度置信网络(DBN)、遗传算法(GA)优化后的SDAE网络以及粒子群算法(PSO)优化后的SDAE网络。

关键词：故障诊断滚动轴承堆叠降噪自编码器超参优化特征提取

Geochemical characteristics of REY, Li, Ga trace elements in the No. 9 coal seam of the Daheng mine, Ningwu coalfield, Shanxi Province, China

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China Geology 2021年第2期4卷 266-273页

作者： Jin-xi Wang Zhi-heng Fu Ya-fan Hu Zhen Yang jia-liang Ma Yu-zhuang Sun Key Laboratory of Resource Exploration Research of Hebei Province Hebei University of EngineeringHandan 056038China School of Resources and Geosciences China University of Mining and TechnologyXuzhou 221116China Institute for Atmospheric and Environmental Sciences Faculty of Geoscience and GeographyGoethe-University FrankfurtFrankfurt am Main 60438Germany

To understand the geochemical characteristics of the No.9 coal in the Daheng Mine of the Ningwu coalfield,the trace element analysis was conducted through X-ray fluorescence spectroscopy(XRF)and inductively coupled plasma mass spectrometry(ICP-MS).The sedimentary environment was discussed according to the element geochemical *** results show that Li,Ga,Hf,Zr,Nb,Th,and Ta are slightly enriched in the No.9 coal of Daheng *** average value of the rare earth elements and yttrium(ΣREY)in coal here is 144.20μg/g(excluding parting),which is higher than the average value ofΣREY in the world’s coal and China’s *** light rare earth elements(LREY)are *** content of Eu was 0.12‒2.10μg/g with an average of 0.57μg/g,and the Eu is obviously negatively *** of the trace elements in the coal are positively correlated with the ash content,which shows that the occurrence of these trace elements is related to inorganic *** results of sequential chemical extraction experiments show that rare earth elements mainly exist in coal in the form of *** value of the Sr/Ba and the content of S reflect that the coal-forming environment was influenced by *** values of V/Cr and Ni/Co reflect that the peat swamp is in an anaerobic environment and a strongly reducing environment during the coal-forming period.

关键词： Trace elements Rare earth elements Geochemistry Coal Taiyuan Formation Mineral exploration engineering Shanxi Province China

Effects of the Anthropogenic Activities on the Morphological Evolution of the Modaomen Estuary, Pearl River Delta, China

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China Ocean Engineering 2013年第6期27卷 795-808页

作者：贾良文潘顺琪吴超羽 Coastal Ocean Research Center Sun Yat-sen University School of Engineering Cardiff University

Owing to the intensive human activities, the Modaomen Estuary has been significantly modified since 1950s, which has resulted in considerable changes of hydrodynamics and morphodynamics in the area. In this paper, the effects of the anthropogenic activities on the hydrodynamics and morphological evolution in the estuary at different stages are systematically assessed based on the detailed bathymetric data and field survey. The results show that the human activities have caused the channelization of the enclosed sea area in the Modamen Estuary;fast seaward movement of the mouth bar with high siltation;expansion of the channel volume due to channel deepening. The paper also highlights the main hydrodynamic changes in the estuary, including the rise of the water level;the distinguishing changes of tidal range before and after the 1990s （decrease and increase respectively）; as well as the increase of the divided flow ratio. It is found that reclamation is the main factor promoting the transition of nature of the estuary from runoff dominant to runoff and wave dominant, and sand mining activities are mainly to strengthen the tidal dynamic and to low the water level. The results provide useful guidance for better planning of the future developments in the estuary and further research in the area.

关键词： Modaomen Estuary anthropogenic activities morphological evolution reclamation sand mining