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Journal of Energy Chemistry 2025年第1期100卷 215-225页

作者： ji.ye li.shuang pan Yihuang Chen Qiong liu College of Chemistry and Materials Engineering Wenzhou University Guangdong Provincial Key Laboratory of Chemical Measurement and Emergency Test Technology (China) Institute of Analysis Guangdong Academy of Sciences (China National Analytical CenterGuangzhou)

Photocatalytic oxygen reduction for hydrogen peroxide （H2O2） synthesis presents a green and costeffective production ***,achieving highly selective H2O2synthesis remains challenging,necessitating precise control over free radical reaction pathways and minimizing undesirable oxidative ***,we report for the visible light-driven simultaneous co-photocatalytic reduction of O2to H2O2and oxidation of biomass using the atomic rubidium-nitride modified carbon nitride（CNRb）.The optimized CNRb catalyst demonstrates a record photoreduction rate of 8.01 mM h-1for H2O2generation and photooxidation rate of 3.75 mM h-1for furfuryl alcohol to furoic acid,achieving a remarkable solar-to-chemical conversion （SCC） efficiency of up to 2.27%.Experimental characterizations and DFT calculation disclosed that the introducing atomic Rb–N configurations allows for the high-selective generation of superoxide radicals while suppressing hydroxyl free radical *** is because the Rb–N serves as the new alternative site to perceive a stronger connection position for O2adsorption and reinforce the capability to extract protons,thereby triggering a high selective redox product *** study holds great potential in precisely regulating reactive radical processes at the atomic level,thereby paving the way for efficient synthesis of H2O2coupled with biomass valorization.

关键词： Free radical reactions

Self-assembled carbon monoxide nanoprodrug for chemiexcitationtriggered synergistic chemotherapy against breast cancer

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Science China Chemistry 2025年

作者： Shunfei Cui Yiyao pan Chenzhe Ma Bin Qi Qingqiang Min Ming li Huabing Chen Hengte Ke Xingyue ji jiangsu Province Engineering Research Center of Precision Diagnostics and Therapeutics Development College of Pharmaceutical ScienceSoochow University

Carbon monoxide（CO） has recently been well-established as a promising therapeutic modality against cancer. The development of transition-metal-free and tumor-targeted delivery platforms for CO is highly demanded but remains very sporadic. Herein, we developed a polyprodrug system for the co-delivery of CO and a chemotherapeutic agent combretastin A-4（CA-4） to the tumor site based on a chemiexcitation mechanism. Such a poly-prodrug successfully achieved the co-activation of CO and CA-4 in response to H2O2at the tumor site both in vitro and in vivo. Importantly, a synergist effect between CO and CA-4 was observed in suppressing tumor growth in a mouse tumor model. It is anticipated that such a poly-prodrug system could be potentially adapted for the co-delivery of CO and another drug payload for combinational therapy for other indications.

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Design of a terahertz slotted waveguide array antenna based on photonic crystal

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Optoelectronics Letters 2025年

作者： pan Wu ye Kuan ZHANG Zhen li Renpu QIU Sen HUANG Lei College of Photoelectronic Engineering， Chongqing University of Posts and Telecommunications Chongqing Municipal Key Laboratory of Photoelectric Information Sensing and Transmission Technology， Chongqing University of Posts and Telecommunications Laboratory of Quantum Information Technology， Chongqing University of Posts and Telecommunications

In this paper， a terahertz slotted waveguide array antenna is designed based on photonic crystal， which can realize efficient radiation of terahertz waves. The electromagnetic wave is fed from the rectangular waveguide at the bottom of the antenna， coupled to photonic crystal waveguide through photonic crystal cavity， and radiated outward through slots at the top layer of antenna. The simulation results show that the antenna achieves a peak gain of 13.45dBi at 360 GHz， a half-power beamwidth of 10.9o， and a side lobe level of -13.9dB. The antenna based on photonic crystal has the advantages of low profile， low loss， and high radiation efficiency， which can be applied to terahertz wireless communication systems.

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Skeletal muscle-specific Bambi deletion induces hypertrophy and oxidative switching coupling with adipocyte thermogenesis against metabolic disorders

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Science China life Sciences 2025年

作者： Xiangping Yao Xudong Mai ye Tian Yifan liu Guanghui jin Ze li Shujie Chen Xiaoshuang Dai liujing Huang Zijing Fan Guihua pan Xiaohan pan Xiangmin li Michael C Yu jia Sun jingxing Ou Hong Chen liwei Xie College of life and Health Sciences Guangdong Industry Polytechnic Department of Endocrinology and Metabolism Zhujiang Hospital Southern Medical University State Key Laboratory of Applied Microbiology Southern China Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application Guangdong Open Laboratory of Applied MicrobiologyInstitute of Microbiology Guangdong Academy of Sciences Institute of Aging Research Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics School of Medical Technology Guangdong Medical University Department of Hepatic Surgery and liver transplantation Center of the Third Affiliated Hospital Organ Transplantation Institute Sun Yat-sen University Organ Transplantation Research Center of Guangdong ProvinceGuangdong province engineering laboratory for transplantation medicine Guangdong Provincial Key Laboratory of Liver Disease Research School of Public Health Xinxiang Medical University BGI Institute of Applied Agriculture BGI-Shenzhen Department of Applied Biology and Chemical Technology The Hong Kong Polytechnic University Department of Biological Sciences State University of New York at Buffalo Department of Internal Medicine Shunde Women and Children's Hospital (Maternity and Child Healthcare Hospital of Shunde Foshan) Guangdong Medical University

Skeletal muscle plays a significant role in both local and systemic energy metabolism. The current investigation aims to explore the role of the Bambi gene in skeletal muscle, focusing on its implications for muscle hypertrophy and systemic metabolism. We hypothesize that skeletal muscle-specific deletion of Bambi induces muscle hypertrophy, improves metabolic performance, and activates thermogenic adipocytes via the reprogramming of progenitor of i WAT, offering potential therapeutic strategies for metabolic syndromes. Leveraging the Chromatin immunoprecipitation(ChIP)-seq and bioinformatics analysis, Bambi gene is shown to be a direct target of HIF2α, which is further confirmed by ChIP-qPCR and promoter luciferase assay. Skeletal muscle-specific Bambi deletion led to significant muscle hypertrophy and improved metabolic parameters, even under high-fat diet conditions. This deletion induced metabolic reprogramming of stromal vascular fractions(SVFs) into thermogenic adipocytes, contributing to systemic metabolic improvements, potentially through the secretory ***, mice with skeletal muscle-specific Bambi deletion demonstrate resistance to high-fat diet-induced metabolic disorders, highlighting a potential therapeutic pathway for metabolic syndrome management. Thus, skeletal muscle-specific deletion of Bambi triggers muscle growth, enhances metabolic performance, and activates thermogenic adipocytes. These findings suggest Bambi as a novel therapeutic target for metabolic syndromes, providing new insights into the interaction between muscle hypertrophy and systemic metabolic improvement. The study underscores the potential of manipulating muscle physiology to regulate whole-body metabolism, offering a novel perspective on treating metabolic disorders.

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Bullous pemphigoid associated with acquired hemophilia A: A case report

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World Journal of Clinical Cases 2025年第4期13卷 28-33页

作者： Su-ye Hu Meng-Can li Zi-jia Hao Xu-Ya Chai Pei-Sai li Yang liu li-Xia liu Ying Xu pan-pan Yang ling-E li Department of Dermatology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina Graduate School Hebei University of Traditional Chinese MedicineShijiazhuang 050051Hebei ProvinceChina Department of Pathology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina

BACKGROUND Acquired hemophilia A (AHA) is a rare and potentially severe bleeding disordercaused by circulating autoantibodies against factor Ⅷ (FⅧ). In approximately50% of the patients, the condition is associated with autoimmune diseases,cancers, medication use, pregnancy, and the post-partum period. Bullous pemphigoid(BP) is a chronic autoimmune subepidermal blistering disease associatedwith tissue-bound and circulating autoantibodies against BP antigens 180 (BP180)and 230 (BP230). AHA-associated BP has a high mortality rate;hence, the understandingof this disease must *** SUMMARY A 69-year-old man presented with erythema, blisters, blood blisters, and crustsaccompanied by severe pruritus for more than 20 days, and ecchymosis andswelling on his left upper arm for 3 days. Pathological examination revealed asubepidermal blister that contained eosinophils. Laboratory tests showed that theBP180 autoantibody levels had increased, isolated activated partial thromboplastintime was notably prolonged (115.6 s), and coagulation FⅧ activity wasextremely low (lity rate. Therefore, its timely diagnosis and effectivetreatment are necessary.

关键词： Bullous pemphigoid Acquired hemophilia A Acquired hemophilia A FactorⅧ Case report

Effects of La addition on the microstructure and tensile properties of Al-Si-Cu-Mg casting alloys

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International Journal of Minerals,Metallurgy and Materials 2015年第4期22卷 405-410页

作者： Tao Lu ye pan ji-li Wu Shi-wen Tao Yu Chen School of Materials Science and Engineering Southeast University jiangsu Key Laboratory of Advanced Metallic Materials Southeast University

The effects of La addition on the microstructure and tensile properties of B-refmed and Sr-modified A1-1 1Si-1.5Cu-0.3Mg cast- ing alloys were investigated. With a trace addition of La （0.05wt%-0. lwt%）, the mutual poisoning effect between B and Sr can be neutral- ized by the formation of LaB6 rather than SrB6. By employing a La/B weight ratio of 2：1, uniform microstructures, which are characterized by well refined ct-A1 grains and adequately modified eutectic Si particles as well as the incorporation of precipitated strengthening intermetal- lics, are obtained and lead to appreciable tensile properties with an ultimate tensile strength of 270 MPa and elongation of 5.8%.

关键词： aluminum silicon alloys rare earth addition lanthanum microstructure tensile properties precipitates

Synthesis, Crystal Structure and Theoretical Calculations of a New Co(Ⅱ) Coordination Polymer Based on 5-Nitroisophthalic Acid and Bis(imidazol) ligands

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Chinese Journal of Structural Chemistry 2016年第2期35卷 298-306页

作者： li Xiu-Mei SUN Ming pan Ya-Ru ji jian-ye Faculty of Chemistry Tonghua Normal University College of Plant Science Jilin Agriculture Science and Technology College

A new complex[Co（NIPH）（mbix）]n（1,H2NIPH = 5-nitroisophthalic acid,mbix =l,3-bis（imidazol-l-ylmethyl）benzene） has been hydrothermally synthesized and structurally characterized by elemental analysis,IR spectrum,UV spectrum,TG and single-crystal X-ray *** crystals crystallize in the triclinic system,space group P1 with a = 8.3797（8）,b= 10.2522（10）,c= 13.4244（13） A,α=94.820（2）,β=108.105（2）,γ=104.816（2）°,V=1042.84（17） A^3,C（22）H（17）CoN5O6,Mr = 506.34,Dc = 1.613 g/cm^3,F（000） = 518,Z = 2,μ（MoKα） =0.876 mm^（-1）,the final R = 0.0505 and wR = 0.1254 for 3267 observed reflections（I〉2σ（I））.The structure of 1 exhibits a two-dimensional network structure and is extended into a three-dimensional supramolecule through hydrogen bonds and n-n *** addition,Natural Bond Orbital（NBO） analysis was performed by using the PBE0/LANL2 DZ method built in Gaussian 09 *** calculation results showed obvious covalent interactions between the coordinated atoms and Co（Ⅱ） ion.

关键词： hydrothermal synthesis crystal structure cobalt complex natural bond orbital

Age, alcohol, sex, and metabolic factors as risk factors for colonic diverticulosis

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World Journal of Clinical Cases 2022年第1期10卷 136-142页

作者： ye Yan jian-Sheng Wu shuang pan Department of Gastroenterology The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina

BACKGROUND The pathogenesis of colonic diverticulosis is not well ***,only a few studies on colonic diverticulosis have been reported in China's *** To evaluate the prevalence of and risk factors for asymptomatic colorectal diverticulosis in Eastern *** From August 2016 to July 2020,6180 asymptomatic individuals were enrolled in this cross-sectional *** individuals had undergone physical examinations,laboratory testing,and *** regarding the baseline characteristics and their general health status were obtained through *** The prevalence of colonic diverticulosis was 7.3%(449/6180).Colonic diverticulosis was detected predominantly on the right side of the colon(88.4%).Logistic regression analysis revealed that an age≥60 years(adjusted odds ratio[OR]2.149,95%confidence interval[CI]1.511-3.057,Plic-related factors,such as hypertension,hypertriglyceridemia,and hyperuricemia,were independent risk factors for colonic *** the true prevalence of colonic diverticulosis and its associated risk factors will aid in its prevention and treatment.

关键词： Aged Alcohol drinking Colonic diverticulosis Hypertension Obesity

Layer-wise domain correction for unsupervised domain adaptation

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Frontiers of Information Technology & Electronic Engineering 2018年第1期19卷 91-103页

作者： shuang li Shi-ji SONG Cheng WU Automation Department Tsinghua University

Deep neural networks have been successfully applied to numerous machine learning tasks because of their impressive feature abstraction ***,conventional deep networks assume that the training and test data are sampled from the same distribution,and this assumption is often violated in real-world *** address the domain shift or data bias problems,we introduce layer-wise domain correction(LDC),a new unsupervised domain adaptation algorithm which adapts an existing deep network through additive correction layers spaced throughout the *** the additive layers,the representations of source and target domains can be perfectly *** corrections that are trained via maximum mean discrepancy,adapt to the target domain while increasing the representational capacity of the *** requires no target labels,achieves state-of-the-art performance across several adaptation benchmarks,and requires significantly less training time than existing adaptation methods.

关键词： Unsupervised domain adaptation Maximum mean discrepancy Residual network Deep learning

A Vanishing Theorem on a Class of Hartogs Domain

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Acta Mathematica Sinica,English Series 2023年第1期39卷 1-12页

作者： Cheng Chen ZHONG An WANG li.shuang pan School of Mathematical Sciences Peking UniversityBeijing 100871P.R.China School of Mathematical Sciences Capital Normal UniversityBeijing 100048P.R.China Science College Shijiazhuang UniversityHebei 050035P.R.China

In this paper,we consider the d-boundedness of the Bergman metric and a vanishing theorem of L2-cohomology on a class of Hartogs domain,whose base domain is the production of two irreducible bounded symmetric domains ... 详细信息

关键词： d-bounded vanishing theorem Bergman metric