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The source of lithium in Lakkor Co Salt Lake on Qinghai-Tibet Plateau,china:evidence from hydrochemical characteristics and boron isotope

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Acta Geochimica 2024年第5期43卷 933-946页

作者： Zheng Yan li bin Kai li Mao-Yong He Xue Qin Wen jiang Di Zhou department of Geoscience and Technology Taiyuan University of TechnologyYingzexi StreetTaiyuan 030024Shanxi ProvinceChina State Key Laboratory of Loess and Quaternary Geology Institute of Earth EnvironmentChinese Academy of SciencesXi’an 710061China Qinghai Provincial Key Laboratory of Geology and Environment of Salt Lakes Qinghai Institute of Salt LakesChinese Academy of SciencesXining 810008QinghaiChina School of Earth Science and Resources Chang’an UniversityXi’an 710000ShaanxiChina Qinghai normal university Academy of Plateau Science and SustainabilityXining 810016China

The availability of lithium resources is of great significance for the development of modern technologies,as well as for civil and military *** Qinghai-Tibet Plateau is a region known for its abundance of lithium-rich salt ***,the specific origin of lithium in these lakes is still unknown,which hinders the advancement of the lithium resource business in this *** research this issue,this study involved the collection of 20 samples from Lakkor Co Salt Lake on Qinghai-Tibet Plateau,encompassing samples of surface brine,cold springs,fresh lakes,and recharge *** composition of anions and cations in these samples was ***,the analysis extensivelyutilizedthePiperthree-linediagram,Gibbs model,and ion proportion *** findings of this study indicate that as the moves from the recharge water system to salt lake,there is a transition in water type from strong carbonate to moderate carbonate and weak carbonate,as well as Na *** research based on a similar source of both lithium and boron,utilized ion correlation analysis and boron isotope study in the Lakkor Co area,and analyzed the source and transporting process of *** main origin of lithium in Lakkor Co is the dissolution of lithiumrich rocks,recharge water systems,and deep hydrothermal *** findings are highly significant in enhancing the foundational data of lithium-rich brine resources in the Qinghai-Tibet Plateau and are beneficial for assessing the future development of such deposits.

关键词： lithium Hydrochemical li-rich Salt lake Boron isotope

Cr^(3+) activated Na_(3)RESi_(3)O_(9)(RE=Y,Lu,Sc) silicate broadband near-infrared phosphors for luminescence towards NIR-Ⅱ region via a multi-site occupancy strategy

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Journal of Rare Earths 2024年第8期42卷 1447-1457,I0002页

作者： jiantong Wang Changshuai Gong Sihan Yang Qi Zhu Xuejiao Wang ji-Guang li College of Chemistry and Materials Engineering Bohai UniversityJinzhou121007China Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education) School of Materials Science and EngineeringNortheastern UniversityShenyang110819China Research Center for Electronic and Optical Materials National Institute for Materials ScienceTsukubaIbaraki 305-0044Japan

Phosphor-converted near-infrared light-emitting diodes(NIR pc-LEDs) are finding applications in various fields including food quality analysis,biomedical imaging,night vision,and *** crucial factor in the development of NIR pc-LEDs devices lies in the advancement of high-performance broadband NIR phosphors,In this work,novel Cr^(3+)-activated silicate phosphors NaRESi_(3)O_(9)(RE=Y,Lu,Sc) are *** silicate has a special 3D network structure in which RE has four different sites,forming four octahedrons and providing suitable occupation sites for Cr^(3+).The phosphors demonstrate a wide emission spectrum ranging from 750 to 1450 nm when excited by light at 468 *** full width at half maximum(FWHM),which benefits from the presence of Cr^(3+)ions occupying multiple sites,is measured to be 203 ***,the strongest emission peak is observed at a longer wavelength of 984 nm compared to most other systems activated by Cr^(3+).The Na_(3)ScSi_(3)O_(9) lattice provides a weak crystal field(Dq/B=1.97) and weak phonon-photon coupling for Cr^(3+),and the integrated emission intensity of Na_(3)ScSi_(3)O_(9):0,03Cr^(3+)is 4.66 times stronger than that of Na_(3)YSi_(3)O_(9):0.03Cr^(3+).

关键词： Rare earths Broadband near-infrared Silicate Photoluminescence Cr^(3+)

Uniquely ergodic property of minimal probability measure in positive definite Lagrangian systems

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Science china mathematics 2006年第12期49卷 1864-1866页

作者： CHEN jing & BAI Yuzhen department of mathematics, Nanjing university, Nanjing 210093, china department of mathematics, Qufu normal university, Qufu 273165, china 1. department of mathematics Nanjing University Nanjing 210093 China 2. department of mathematics Qufu Normal University Qufu 273165 China

Mane conjectured that every minimal measure in the generic Lagrangian systems is uniquely ergodic. In this paper, we will show that the answer to the Mane's conjecture is negative by analyzing the structure of the sup... 详细信息

关键词： minimal probability measure,uniquely ergodic,Mather theory,Lagrangian systems.

Decomposition of integrable holomorphic quadratic differential on Riemann surface of infinite type

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Science china mathematics 2010年第8期53卷 2039-2044页

作者： CHENG Tao department of mathematics,East china normal university,Shanghai 200241,china 1. department of mathematics East China Normal University Shanghai 200241 China

In this paper,decomposition of the integrable holomorphic quadratic differential on Riemann surface of infinite type is ***,Schleicher and Shishikura gave a thick-thin decomposition on Riemann surface of finite type with an integrable holomorphic quadratic differential and they thought their result might be generalized to arbitrary hyperbolic Riemann surface of infinite *** confirm what they thought is right and give a proposition(Proposition 2.2) of its own interest.

关键词： holomorphic quadratic differential decomposition collar

Strategies that regulate LSD1 for novel therapeutics

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Acta Pharmaceutica Sinica B 2024年第4期14卷 1494-1507页

作者： Meng li Mengge Dai bing Cheng Shaotong li Enhui Guo Junwei Fu Ting Ma bin Yu School of Pharmaceutical Sciences&Key Laboratory of Advanced Drug Preparation Technologies Ministry of EducationZhengzhou UniversityZhengzhou 450001China College of Chemistry Zhengzhou UniversityZhengzhou 450001China Tianjian Laboratory of Advanced Biomedical Sciences Institute of Advanced Biomedical SciencesZhengzhou UniversityZhengzhou 450000China Pingyuan Laboratory State Key Laboratory of Antiviral DrugsHenan Normal UniversityXinxiang 453007China State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjing 210023China

Histone methylation plays crucial roles in regulating chromatin structure and gene transcrip-tion in epigenetic ***-specific demethylase 1(LSD1),the first identified histone de-methylase,is universally overexpressed in various ***1 dysregulation is closely associated with cancer,viral infections,and neurodegenerative diseases,etc.,making it a promising therapeutic *** LSD1 inhibitors and two small-molecule degraders(UM171 and BEA-17)have entered the clinical ***1 can remove methyl groups from histone 3 at lysine 4 or lysine 9(H3K4 or H3K9),resulting in either transcription repression or *** the roles of LSD1 in transcrip-tional regulation are well-established,studies have revealed that LSDl can also be dynamically regulated by other *** example,the expression or activity of LSD1 can be regulated by many proteins that form transcriptional corepressor complexes with ***,some post-transcriptional modifica-tions and cellular metabolites can also regulate LSD1 expression or its demethylase ***,in this review,we will systematically summarize how proteins involved in the transcriptional corepressor complex,various post-translational modifications,and metabolites act as regulatory factors for LSD1 ac-tivity.

关键词： LSD1 regulation Transcription repression Transcription activation the Corepressor complex Post-transcriptional modifications Metabolites

The pointwise dimension of self-similar measures

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Chinese Science Bulletin 1999年第23期44卷 2136-2140页

作者： CHEN Ercai and XIONG jincheng department of mathematics , Nanjing normal university , Nanjing 210097, china department of mathematics , South china normal university, Guangzhou 510631 , china department of mathematics Nanjing Normal University Nanjing China department of mathematics South China Normal University Guangzhou China

The problem about the existence of pointwise dimension of self-similar measure has been discussed. The Hausdorff dimension of the set of those points for which the pointwise dimension does not exist equals the dimenti... 详细信息

关键词： self-similar measure point wise dimension Hausdorff dimension multifractal symbolic space.

Visual and portable detection of metronidazole realized by metal-organic framework flexible sensor and smartphone scanning

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Chinese Chemical Letters 2024年第10期35卷 500-504页

作者： Xiangshuai li jian Zhao li Luo Zhuohao jiao Ying Shi Shengli Hou* bin Zhao department of Chemistry Key Laboratory of Advanced Energy Materials ChemistryRenewable Energy Conversion and Storage Center(RECAST)Nankai UniversityTianjin 300071China

Metronidazole(MNZ)is a type of antibiotic that can help people and animals cure bacterial in fections,however,abuse of MNZ has posed a threat to human ***,portable and vi sual detection of MNZ is meaningful for food safety and rational administration of drugs,bu full of ***,a porous three-dimensional Tb-based metal-organic framework(MOF{(CH_(3))_(2)NH_(2)·[Tb_(5)(TDA)_(8)(H_(2)O)_(2)]·6DMF·2C_(2)H_(5)OH}_n(TDA-Tb)with good solvent and p H stabilities was pre pared,and the framework possesses one-dimensional channels with a diameter of 12 A along the c-axis Experiment results suggest that the synthesized TDA-Tb can selectively and sensitively detect MNZ in water,and the limit of detection(LOD)is as low as 4.1×10^(-7)mol/***,a flexible sensor TDA Tb-M was also constructed by incorporating TDA-Tb into membrane materials for convenient *** the TDA-Tb-M firstly realized portable and visual detection of MNZ through smartphone scanning,which may inspire more probes with wide application ranges.

关键词： Metal-organic framework Lanthanide Luminescence Antibiotic Sensor

Identification of transient receptor potential channel genes and functional characterization of TRPA1 in Spodoptera frugiperda

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Journal of Integrative Agriculture 2024年第6期23卷 1994-2005页

作者： Yutong Zhang Hangwei liu Song Cao bin li Yang liu Guirong Wang State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureGenome Analysis Laboratory of the Ministry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China Institute of Evolution and Ecology School of Life SciencesCentral China Normal UniversityWuhan 430079China

Spodoptera frugiperda is a highly destructive pest that has become a global problem due to its robust reproductive and migratory *** receptor potential(TRP)channels,which constitute a vast ion channel family,play pivotal roles in sensing the external environment and maintaining internal homeostasis in *** channels have been widely investigated for their critical roles in regulating various insect behaviors in recent *** this study,we identified 15 TRP gene loci encoding 26 transcripts in the genome of *** and analyzed their expression profiles at different developmental *** results revealed that *** possesses four TRPC genes,six TRPA genes,one TRPM gene,two TRPV genes,one TRPN gene,and one TRPML gene,while a canonical TRPP is ***,the SfruTRPA1 was functionally characterized using the Xenopus oocyte expression *** results showed that SfruTRPA1 is activated by temperature increases from 20 to 45℃,and there is no significant desensitization after repeated stimuli within the same temperature ***,SfruTRPA1 is activated by certain natural chemicals,including allyl isothiocyanate(AITC)and cinnamaldehyde(CA).These findings provide valuable insights to the TRP genes in ***.

关键词： Spodoptera frugiperda transient receptor potential channel expression profile TRPA1 Xenopus oocyte

Efficacy and safety of Qingfei Huatan formula in the treatment of acute exacerbation of chronic obstructive pulmonary disease:A multi-centre,randomised,double-blind,placebo-controlled trial

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Journal of Integrative Medicine 2024年第5期22卷 561-569页

作者： Hui-zhi Zhu Cheng-yi li liang-ji liu jia-bing Tong Zhi-hui Lan Shu-guang Tian Qiao li Xiang-li Tong ji-feng Wu Zhen-gang Zhu Su-yun li jian-sheng li department of Respiratory Medicine the First Affiliated Hospital of Anhui University of Traditional Chinese MedicineHefei 230031Anhui ProvinceChina Graduate School Anhui University of Traditional Chinese MedicineHefei 230012Anhui ProvinceChina department of Respiratory Medicine Affiliated Hospital of Jiangxi University of Traditional Chinese MedicineNanchang 330006Jiangxi ProvinceChina department of Respiratory Diseases the First Affiliated Hospital of Henan University of Traditional Chinese MedicineZhengzhou 450000Henan ProvinceChina department of Pulmonary Diseases Taihe Hospital of Traditional Chinese Medicine Affiliated to Anhui University of Traditional Chinese MedicineFuyang 236600Anhui ProvinceChina department of Respiratory and Critical Care Medicine Jiangxi Province Hospital of Integrated Chinese and Western MedicineNanchang 330002Jiangxi ProvinceChina department of Respiratory Medicine the First Affiliated Hospital of Tianjin University of Traditional Chinese MedicineTianjin 300381China Collaborative Innovation Center for Respiratory Disease Diagnosis and Treatment and Chinese Medicine Development of Henan Province Zhengzhou 450046Henan ProvinceChina

Background Chronic obstructive pulmonary disease(COPD),a common respiratory disease,can be effectively treated by traditional Chinese medicine(TCM).Qingfei Huatan,a TCM formula,has been reported to effectively alleviate the clinical symptoms of COPD ***,there is a lack of multi-centre,randomised,double-blind,controlled clinical trials documenting the clinical efficacy and safety of this formula in the treatment of acute exacerbation of COPD(AECOPD).Objective This study evaluated the efficacy and safety of Qingfei Huatan formula in the treatment of AECOPD,thereby providing high-quality clinical ***,setting,participants and interventions A total of 276 patients with AECOPD were included in this multi-centre,randomised,double-blind,placebo-controlled trial and were randomised into treatment and control groups at a ratio of 1:*** in the treatment and control groups took Qingfei Huatan granules or simulated Qingfei Huatan granules twice a day,for 14 days,in addition to Western medicine *** patients were followed up for 3 *** outcome measures The primary outcome was time taken to symptom *** secondary outcomes included duration of antibiotic use,clinical symptom and sign score,TCM syndrome score,dyspnoea score,and quality of life(QOL)***,the safety of the formula was assessed through routine urine and stool tests,electrocardiograms,liver and kidney function tests,and the observation of adverse events throughout the *** The time taken for effective stabilisation(Plisation(Plinical symptom and sign score decreased in both groups,particularly in the treatment group(P<0.01).On days 9,12 and 14 of treatment,the TCM syndrome scores of both groups were reduced(P<0.01),with more significant reductions in the treatm

关键词： Acute exacerbation of chronic obstructive pulmonary disease Clinical trial Syndrome of phlegm-heat congesting lung Qingfei Huatan formula Traditional Chinese medicine