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Dextran-modified iron oxide nanoparticles

China Particuology 2007年第1期5卷 162-168页

作者： jií hradil Alexander Pisarev Michal Babi Daniel Hork Institute of Macromolecular Chemistry Academy of Sciences of the Czech Republic Heyrovsky Sq. 2 162 06 Prague Czech Republic

Dextran-modified iron oxide nanoparticles were prepared by precipitation of Fe（Ⅱ） and Fe（Ⅲ） salts with ammonium hydroxide by two methods. Iron oxide was precipitated either in the presence of dextran solution, or the dextran solution was added after precipitation. In the second method, the iron oxide particle size and size distribution could be controlled depending on the concentration of dextran in the solution. The nanoparticles were characterized by size-exclusion chromatography, transmission electron microscopy and dynamic light scattering. Optimal conditions for preparation of stable iron oxide colloid particles were determined, The dextran/iron oxide ratio 0-0,16 used in precipitation of iron salts can be recommended for synthesis of nanoparticles suitable for biomedical applications, as the colloid does not contain excess dextran and does not coagulate.

关键词： Iron oxide Nanoparticles Dextran Size-exclusion chromatography Particle size

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An Alternative Electroplating Technology for Mass Finishing of Chip Capacitors and Resistors

An Alternative Electroplating Technology for Mass Finishing ...

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2003年全国电子电镀学术研讨会

作者： George A.Federman George hradil Technic Advanced Technology Division 111 E.Ames Ct Plainview NY 11803 Technic Inc.Spectacle St Cranston RI 02910

The rapid pace of miniaturization in the electronics and semi - conductor industries has led to the emergence of discreet micro-sized active components such as connector clips and pins and passive surface mounted components such as chip capacitors,resistors and inductors. These components often require electroplating as a finishing step to impart specific corrosion,wear resistance, conductivity and solderability characteristics. However,the size of these components has been reduced so significantly in recent years that conventional means of electroplating are no longer suitable for this *** has even been suggested that the electroplating of these parts is one of the major barriers to further *** also must be noted that electroplating of these parts is the final manufacturing step before the parts are shipped to the *** of the parts at this stage due to problems that occurred during electroplating is very costly.

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皮肤型人乳头瘤病毒DNA在皮肤肿瘤表面高检出,而在活检标本中检出率低

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世界核心医学期刊文摘（皮肤病学分册） 2005年第1期1卷 54-55页

作者： Forslund O. Lindelf B. hradil E. 崔荣 Department of Medical Microbiology Malmo University Hospital SE-205 02 Malmo Sweden

Genomes of human papillomaviruses (HPV) are common in biopsies from non-melanoma skin cancers but are also found on healthy skin and it is possible that HPV positivity in tumor biopsies by PCR maymerely reflect contamination of the lesion *** investigate this issue, 229 immunocompetent patients were tested for HPV DNA in swab samples collected on top of skin tumors and in biopsies of the same tumors, obtained after stripping with tape to remove superficial *** DNA was detected on top of 69%(159 of 229) of the lesions, and in 12%(28 of 229) of the stripped biopsies (p < 0.001).The difference was seen for all four types of tumors *** keratosis had 79%(34 of 43) HPV positivity on top of lesions versus 19%(eight of 43) in biopsies; actinic keratosis had 83%(38 of 46) HPV positivity on top versus 11%(five of 46) in biopsies; basal cell carcinoma had 63%(69 of 109) on top versus 8%(nine of 109) in biopsies and squamous cell carcinoma had 58%(18 of 31) on top versus 19%(six of 31) in *** DNA is common in superficial layers of lesions, but is not necessarily present throughout tumors.

关键词：皮肤肿瘤人乳头瘤病毒活检标本皮肤型脂溢性角化病基底细胞癌拭子角化症光化性鳞状细胞癌

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HETEROGENEOUS MEMBRANES FOR SEPARATION OF SMALL MOLECULES

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Chinese Journal of Reactive Polymers 2000年第F5期9卷 17-17页

作者： J.hradil V.Krystl 等 InstituteofMacromolecularChemistry AcademyofSciencesoftheCZECHRepublicPrague6 PragueInstituteofChemicalTechnology Prague6CZECH

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