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Knowledge of Cervical Cancer and Prevalence of the Screening Services among HIV-Infected Women in Blantyre, Malawi

Health 2020年第11期12卷 1496-1510页

作者： jessie Mkandawire Flemmings Fishani Ngwira Fresier Chidyaonga Maseko School of Public Health and Family Medicine College of Medicine University of Malawi Zomba Malawi The Polytechnic Language and Communication Department University of Malawi Zomba Malawi

HIV-infected women are at high risk of developing cervical cancer and are encouraged to undergo cervical cancer screening regularly. However, very little has been documented about the knowledge of cervical cancer and the utilization of the screening services by these women. This study aimed to investigate the knowledge of cervical cancer, prevalence of cervical cancer screening uptake and predictive factors that affect utilization of cervical cancer screening services among HIV-infected women. The study employed quantitative methods for data collection and analysis. It was conducted at Queen Elizabeth Central Hospital (QECH) from December 2017 to February 2018 where HIV-positive patients accessing QECH Antiretroviral Therapy (ART) clinic were recruited. Systematic random sampling was employed to select HIV-positive women for the survey. Data were collected using semi-structured questionnaires. STATA version 12 was used to analyze the data. Out of the 196 recruited women, the majority (98%;n = 192) indicated having heard of cervical cancer and of the 192 women, only 57% (n = 109) were able to know at least a single sign/symptom of cervical cancer, furthermore, only 47% (n = 91) indicated ever been screened, finally, getting information from health facilities and knowing at least a single sign/symptom of cervical cancer influenced HIV-infected women to go for cervical cancer screening services. The study revealed that knowledge of cervical cancer and the utilization of its screening services among HIV-infected women is low. Therefore, there is need to increase knowledge and strengthen cervical cancer screening services among HIV-infected women in the country.

关键词： Cervical Cancer Screening Services HIV-Infected Women Knowledge of Cervical Cancer

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在建筑业中数字图像照像技术的应用

在建筑业中数字图像照像技术的应用

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勘察设计企业信息化建设研讨会

作者： David Riley jessie Whitsides 华盛顿大学建筑管理系华盛顿大学建筑管理系

数字照像术提供了一种拍摄、观察和管理现场状况及工程进度图像的技术。在建筑业中,建筑和施工公司有许多利用图形的通讯性质的机会。这篇报告给出对设计和旌工项目中用数字照像取代正在使用的照像服务的可行性进行调查的结果,并制定了... 详细信息

数字照像术提供了一种拍摄、观察和管理现场状况及工程进度图像的技术。在建筑业中,建筑和施工公司有许多利用图形的通讯性质的机会。这篇报告给出对设计和旌工项目中用数字照像取代正在使用的照像服务的可行性进行调查的结果,并制定了鼓励使用这种技术的策略。用书面和会面方式完成了调查,用以评估在建筑公司和施工公司中照像技术的用途及其费用。还进行了试验性的应用,用以估计实际价格、投入培训的时间和数字图像技术为建筑业带来的好处。结论给出了最可能成功地利用数字图像工具的工程类型和技术。

关键词：数字图像照像术互连网

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Optimization of the injection phase of the analysis of pesticides in produce by GC-M S

Optimization of the injection phase of the analysis of pesti...

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30th International Symposium on Capillary Chromatography、4th GC×GC Symposium、16th National Symposium and Exhibition on Chromatography,i.e. 1st Dalian International Symposium and Exhibition on Chromatography

作者： jessie Butler Eric Phillips Thermo Fisher Scientific 2215 Grand Ave Pkwy AustinTX 78728 Thermo Fisher Scientific 2215 Grand Ave Pkwy AustinTX 78728

＜正＞The pesticide chemist has a variety of options to choose from when it comes to sample injection *** more common injection mode is conventional splitless where the inlet is held at a constant temperature and a 1 μL injection is *** injection technique is temperature programmed injection,where the sample is introduced into a cold inlet and then the inlet temperature is rapidly *** second technique is becoming more widely used although the complete understanding of the physical properties involved is not that *** order to either develop a new method for a new list of pesticides or improve the current method,the pesticide chemist may read the literature and see the optimum parameters listed in a publication and attempt to apply them to their particular list,or the preferred approach is to look at the physical properties of the constituents of the extract solution and determine the best injection *** possible the injection technique may be used to minimize the transfer of the matrix while attempting to maintain the transfer efficiency of the target pesticide *** the matrix has a higher boiling point than the target pesticides,they may be eliminated in the inlet clean phase of a temperature programmed injection atfer the transfer of the target pesticides has *** the sensitivity is not achieved with a 1 μL injection,a large volume injection may be used to introduce 10 times more sample.A large volume injection can be made in less than one minute while concentration of an extract can take almost one hour in the wet lab.

关键词： Pesiticide Analysis GC-MS Chromatography Quechers extraction

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单极四杆GC/MS分析VOCs的最新进展

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环境化学 2012年第9期31卷 1462-1463页

作者： jessie Butler David Steiniger Eric Phillips Trisa Robarge Thermo Fisher Scientific Austin Texas USA

根据美国环境保护署（EPA）方法,采用赛默飞世尔公司ISQ单四极杆气质联用仪建立了挥发性有机物（VOCs）的分析检测方法.整个方法所需的仪器包括进样器、气相色谱、质谱、数据处理软件等.为了满足法规中日益严格的检出限要求及新型污染... 详细信息

根据美国环境保护署（EPA）方法,采用赛默飞世尔公司ISQ单四极杆气质联用仪建立了挥发性有机物（VOCs）的分析检测方法.整个方法所需的仪器包括进样器、气相色谱、质谱、数据处理软件等.为了满足法规中日益严格的检出限要求及新型污染物的加入,我们对实验方案进行了改进,以提高检测灵敏度及提高样品通量.

关键词： GC/MS分析 VOCs 美国环境保护署检测灵敏度单极挥发性有机物数据处理软件气质联用仪

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应用GINI检出微卫星不稳定型大肠癌中新的突变基因

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复旦学报（医学版） 2008年第1期35卷 58-62页

作者：徐晓丽汪清 Claudine Navarro jessie Auclair 施达仁复旦大学附属肿瘤医院病理科-复旦大学上海医学院肿瘤学系上海200032 Centre Leon Berard肿瘤医院分子肿瘤学实验室里昂69008法国

目的应用GINI筛选微卫星不稳定型大肠癌中新的突变基因。方法采用NMD抑制药物emetine(依米丁)联合actinomycin D(放线菌素D),分别处理高度微卫星不稳定型(MSI-H)大肠癌细胞株HCT116和微卫星稳定(MSS)的大肠癌细胞株HT29,以及对照的MSS... 详细信息

目的应用GINI筛选微卫星不稳定型大肠癌中新的突变基因。方法采用NMD抑制药物emetine(依米丁)联合actinomycin D(放线菌素D),分别处理高度微卫星不稳定型(MSI-H)大肠癌细胞株HCT116和微卫星稳定(MSS)的大肠癌细胞株HT29,以及对照的MSS乳腺癌细胞株,以全基因组cDNA芯片检测经药物处理和不经药物处理的细胞株的mRNA表达变化。经过芯片数据分析筛选在HCT116细胞中mRNA表达量特异性升高的基因,以DNA直接测序法检测突变,并在22个大肠癌细胞株及30例原发癌组织中验证。结果在MSI-H大肠癌细胞株HCT116中筛选出新的突变基因ARV1和ZNF294,并在8个MSI-H细胞株中验证其突变率分别为37.5%和87.5%,在20例MSI-H原发大肠癌组织中突变率均为35%。结论基于NMD抑制的新的基因筛选方法GINI,能够相对快速、有效的检出发生突变的基因。

关键词： NMD抑制大肠癌微卫星不稳突变

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Herpes Simplex Virus Type 2 Risks in Female Sex Workers in the China-vietnam Border County of Hekou

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Biomedical and Environmental Sciences 2012年第6期25卷 706-710页

作者： WANG Jun Jie ZHU Zhi Bin YANG Xi WU Jing WANG Hai BO FENG Lin DING Guo Wei jessie L. NORRIS WANG Ning National Center for AIDS/STD Control and Prevention Chinese Center for Disease Control and PreventionBeijing 102206 China Hekou Center for Disease Control and Prevention Hekou 661300 Yunnan China Yunnan Center for Disease Control and Prevention Kunming 650022 China

Objective To survey the prevalence and risk factors of HSV-2 among Chinese and Vietnamese female sex workers （FSW） in the border county of Hekou, Yunnan Province, China. Methods A cross-sectional survey was conducted on demographics, sexual behavior, medical history, and drug use among FSWs. Laboratory samples were obtained to test for HSV-2 and other STIs such as HIV, Syphilis, Trichomonas vaginalis, Neisseria gonorrhoeae, Chlamydia trachomatis, Bacterial vaginosis, and Yeast infections. Cervicitis and genital warts were also diagnosed. Results Of the 345 FSWs who participated in this study, 112 （32.5%） were ethnic Chinese and 233 （67.5） were Vietnamese. Among FSWs in Hekou, the prevalence rates were 58.3% for HSV-2, 5.5% for HIV, and 4.1% for bacterial vaginosis （BV）. Age 〈21 （OR： 0.5; 95% CI： 0.3, 0.8）, duration of commercial sex work 〈3 months （OR： 0.5; 95% CI： 0.3, 0.8）, oral and vaginal sex with the last client （as opposed to only vaginal sex）（OR： 1.6; 95% CI： 1.0, 2.7）, HIV （OR： 11.4; 95% Cl： 1.5, 87.2）, and bacterial vaginosis （BV）（OR 5.6; 95% CI： 1.2, 26.9） were significantly correlated with HSV-2 infection. Conclusion Multivariate analysis showed that several factors were significantly correlated with the high prevalence of HSV-2 in FSWs in the border area between China and Vietnam. Further studies and interventions are needed for HSV-2 epidemiology in the border area.

关键词： China Vietnam Female sex workers HSV-2

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Molecular constituents encoding the cardiac pacemaker if currents

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岭南心血管病杂志 2011年第S1期17卷 28-29页

作者： Bin Ye jessie Ou Nian-Qing Shi Department of Medicine cardiovascular Medicine DivisionUniversity of WisconsinMadisonWI53706 USA

Cardiac pacemakers play critical biological functions in generating spontaneous and rhythmic action *** in cardiac pacemaking can be life-threatening,leading to arrhythmia and sudden *** the hyperpolarization-activated,cyclic nucleotide-gated(HCN) channels play a prominent role in both cardiac and neuronal automaticity and excitability,multimerization of HCN1 -4 and the molecular constituents encoding the cardiac If currents have not been completely *** members of the HCN family(HCN1-4) are identified in mammals as each HCN subunit contains a 6- transmembrane core domain and a cyclic nucleotide-binding domain(CNBD).In the myocardium,HCN4 is the most abundantly expressed transcript whereas HCN2 is readily detected in heart and brain tissues. Disruption of HCN4 causes early lethality in mice while mice with a targeted HCN2 display sinus dysrhythmia, which indicate that HCN4 and HCN2 both play important roles in cardiac *** from our group and others suggest that the heterolo-gously expressed HCN4 or HCN2 homomeric channels exhibit much more negative activation potentials relative to those recorded from cardiac cells,suggesting that a homomeric structure may not confer the cardiac If *** hypothesized that a HCN2/ HCN4 heteromeric channel is more likely to be the legitimate composition for cardiac HCN *** full-length HCN2 is estimated at 95-kDa,however, our results show that HCN2 in adult mouse hearts is a 60-kDa short form(designated as HCN2 C),which lacks the entire distal C-terminus including the cAMP regulatory ***,the cAMP-based regulation on the heterologous channel is possibly through the CNBD of HCN4.0ur results indicate that HCN2 C interacts with HCN4 in mouse hearts. We further show that a HCN2 C homomeric channel does not produce any *** HCN2 C is co-expressed with HCN4 in heterologous cells, pacemaking currents are recorded with the time- and voltage-dependent properties clos

关键词： arrhythmia currents encoding neuronal sinus hearts endogenous distal likely targeted

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用姿势控制能力不足确定脑震荡遗留的神经功能缺损（英文）

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Journal of Sport and Health Science 2016年第1期5卷 61-69页

作者： Thomas A.Buckley jessie R.Oldham Jaclyn B.Caccese Department of Kinesiology andApplied Physiology Interdisciplinary Program in Biomechanics and Movement Science 150 Human Performance Laboratory University of Delaware Newark DE 19716 USA Interdisciplinary program in Biomechanics and Movement Science University of Delaware Newark DE 19716 USA

Concussion,or mild traumatic brain injury,incidence rates have reached epidemic levels and impaired postural control is a cardinal *** purpose of this review is to provide an overview of the linear and non-linear assessments of post-concussion postural *** current acute evaluation for concussion utilizes the subjective balance error scoring system(BESS) to assess postural *** the sensitivity of the overall test battery is high,the sensitivity of the BESS is unacceptably low and,with repeat administration,is unable to accurately identify *** measures of postural control,utilizing traditional linear assessments,have identified impairments in postural control well beyond BESS *** assessments of quiet stance and gait have identified lingering impairments for at least 1 month ***,the application of non-linear metrics to concussion recovery have begun to receive limited attention with the most commonly utilized metric being approximate entropy(Ap En).Ap En,most commonly in the medial-lateral plane,has successfully identified impaired postural control in the acute post-concussion timeframe even when linear assessments of instrumented measures are equivalent to healthy pre-injury values;unfortunately these studies have not gone beyond the acute phase of *** study has identified lingering deficits in postural control,utilizing Shannon and Renyi entropy metrics,which persist at least through clinical recovery and return to ***,limited evidence from two studies suggest that individuals with a previous history of a single concussion,even months or years prior,may display altered Ap En ***,non-linear metrics provide a fertile area for future study to further the understanding of postural control impairments acutely post-concussion and address the current challenge of sensitive identification of recovery.

关键词：脑震荡控制姿势神经功能创伤性脑损伤非线性指标缺损 Renyi熵

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