Optimization of the injection phase of the analysis of pesticides in produce by GC-M S
作者单位：Thermo Fisher Scientific 2215 Grand Ave PkwyAustinTX 78728 Thermo Fisher Scientific 2215 Grand Ave PkwyAustinTX 78728
会议名称：《30th International Symposium on Capillary Chromatography、4th GC×GC Symposium、16th National Symposium and Exhibition on Chromatography,i.e. 1st Dalian International Symposium and Exhibition on Chromatography》
会议日期：2007年
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学]
关 键 词：Pesiticide Analysis GC-MS Chromatography Quechers extraction
摘 要：正The pesticide chemist has a variety of options to choose from when it comes to sample injection *** more common injection mode is conventional splitless where the inlet is held at a constant temperature and a 1 μL injection is *** injection technique is temperature programmed injection,where the sample is introduced into a cold inlet and then the inlet temperature is rapidly *** second technique is becoming more widely used although the complete understanding of the physical properties involved is not that *** order to either develop a new method for a new list of pesticides or improve the current method,the pesticide chemist may read the literature and see the optimum parameters listed in a publication and attempt to apply them to their particular list,or the preferred approach is to look at the physical properties of the constituents of the extract solution and determine the best injection *** possible the injection technique may be used to minimize the transfer of the matrix while attempting to maintain the transfer efficiency of the target pesticide *** the matrix has a higher boiling point than the target pesticides,they may be eliminated in the inlet clean phase of a temperature programmed injection atfer the transfer of the target pesticides has *** the sensitivity is not achieved with a 1 μL injection,a large volume injection may be used to introduce 10 times more sample.A large volume injection can be made in less than one minute while concentration of an extract can take almost one hour in the wet lab.