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Efficacy of vasopressin, steroid, and epinephrine protocol for in-hospital cardiac arrest resuscitation: a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis

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Journal of Geriatric Cardiology 2022年第9期19卷 705-711页

作者： Danish Iltaf Satti Yan Hiu Athena Lee Keith Sai Kit Leung jeremy Man Ho Hui Thompson Ka Ming Kot Arslan Babar Gauranga Mahalwar Abraham KC Wai Tong Liu Leonardo Roever Gary Tse Jeffrey Shi Kai Chan International Health Informatics Study(IHIS)Network Cardiovascular Analytics Group Hong KongChina-UK Collaboration Emergency Medicine Unit Li Ka Shing Fac-ulty of MedicineThe University of Hong KongHong KongChina Aston Medical School Faculty of Health&Life SciencesAston UniversityBirminghamUnited Kingdom Li Ka Shing Faculty of Medicine The University of Hong KongHong KongChina Department of Anaesthesia and Pain Service Princess Margaret HospitalLai Chi KokKowloonHong KongChina Department of Medicine Cleveland Clinic FoundationClevelandUSA Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of CardiologyTianjin Institute of Cardi-ologySecond Hospital of Tianjin Medical UniversityTianjinChina Department of Clinical Research Federal Uni-versity of UberlândiaUberlândiaBrazil Kent and Medway Medical School CanterburyKentUnited Kingdom 不详

OBJECTIVES To assess the effect of vasopressin,steroid and epinephrine(VSE)combination therapy on return of spontan-eous circulation(ROSC)after in-hospital cardiac arrest(IHCA),and test the conclusiveness of evidence using trial sequential ana-lysis(TSA).METHODS The systematic search included PubMed,EMBASE,Scopus,and Cochrane Central Register of Controlled *** controlled trials(RCTs)that included adult patients with IHCA,with at least one group receiving combined VSE therapy were *** was extracted independently by two *** main outcome of interest was *** out-comes included survival to hospital discharge or survival to 30 and 90 days,with good neurological *** We included a total of three RCTs(n=869).Results showed that VSE combination therapy increased ROSC(risk ra-tio=1.41;95%CI:1.25-1.59)as compared to *** demonstrated that the existing evidence is *** was also validated by the alpha-spending adjusted relative risk(1.32[1.16,1.49],Prame in the included *** VSE combination therapy administered in cardiopulmonary resuscitation led to improved rates of ***-ture trials of VSE therapy should evaluate survival to hospital discharge,neurological function and long-term survival.

关键词： resuscitation analysis return

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Physics and astrophysics of strong magnetic field systems with eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 74-96页

作者： Andrea Santangelo Silvia Zane Hua Feng RenXin Xu Victor Doroshenko Enrico Bozzo Ilaria Caiazzo Francesco Coti Zelati Paolo Esposito Denis González-Caniulef jeremy Heyl Daniela Huppenkothen Gianluca Israel ZhaoSheng Li Lin Lin Roberto Mignani Nanda Rea Mauro Orlandini Roberto Taverna Hao Tong Roberto Turolla Cristina Baglio Federico Bernardini Niccolo'Bucciantini Marco Feroci Felix Fürst Ersin G??ü? Can Güngör Long Ji FangJun Lu Antonios Manousakis Sandro Mereghetti Romana Mikusincova Biswajit Paul Chanda Prescod-Weinstein George Younes Andrea Tiengo YuPeng Xu Anna Watts Shu Zhang Shuang-Nan Zhang Institut für Astronomie und Astrophysik Eberhard Karls Universität Key Laboratory for Particle Astrophysics Institute of High Energy Physics Mullard Space Science Laboratory University College LondonHolmbury St Mary Department of Engineering Physics and Center for Astrophysics Tsinghua University School of Physics Peking University Department of Astronomy University of Geneva Department of Physics and Astronomy University of British Columbia Universitädell’Insubria Anton Pannekoek Institute for Astronomy University of Amsterdam INAF-Osservatorio Astronomico di Brera Center for Data Science New York University INAF-Osservatorio Astronomico di Roma Department of Physics Xiangtan University Department of Astronomy Beijing Normal University INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica Milano Janusz Gil Institute of Astronomy University of Zielona Góra Instituto de Ciencias del Espacio(ICE) CSIC-IEEC INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica Bologna Department of Physics and Astronomy University of Padova School of Physics and Electronic Engineering Guangzhou University NYU Abu Dhabi Saadiyat Campus P.O. NAF Osservatorio di Arcetri Largo Enrico Fermi 5 INAF-Istituto di Astrofisica e Planetologia Spaziali INFN-Roma Tor Vergata European Space Astronomy Centre(ESA/ESAC) Science Operations Department Sabanci University Faculty of Engineering and Natural Sciences Centrum Astronomiczne im.M.Kopernika Department of Physics Sultan Qaboos University Institute of Theoretical Physics Faculty of Mathematics and PhysicsCharles University in Prague raman Research Institute Sadashivanagar Department of Astronomy University of Washington The George Washington University Physics department 725 21st St NW Scuola Universitaria Superiore IUSS Pavia Palazzo del Broletto

In this paper we present the science potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies of strongly magnetized objects. We will focus on the physics and astrophysics of strongly magnetized objects, namely magnetars, accreting X-ray pulsars, and rotation powered pulsars. We also discuss the science potential of eXTP for QED studies. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Sciences, the eXTP mission is expected to be launched in the mid 2020s.

关键词： neutron stars QED magnetars accreting pulsars eXTP

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