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Statistical estimations for Plasmodium vivax malaria in South Korea

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Asian Pacific Journal of Tropical Medicine 2015年第3期8卷 169-175页

作者： Youngsaeng lee Hyeongap Jang jeong Ae Rhee jeong-Soo Park Department of Statistics Chonnam National University JW lee Center for Global Medicine College of MedicineSeoul National University Department of Preventive Medicine Chonnam National University

Objective:To calculate the numbers of weekly infections and prevalence of malaria,and to predict future trend of malaria incidences in South ***:Weekly incidences of malaria for 13 years from the period 2001-2013 in South Korea were *** backcalculation equations were used with incubation period *** maximum likelihood estimation for Poisson model was also *** confidence intervals of the estimates were obtained by a bootstrap method.A regression model for time series of malaria incidences over13 years was fitted by the non-linear least squares method,and used to predict ***:The estimated infection curve is narrower and more concentrated in the summer than in the incidence *** started around the 19 th week and was over around the41 st *** maximum weekly infection 110 was obtained at the 29 th *** prevalence at the first week was around 496 persons,the minimum number was 366 at 22 nd week,and the maximum prevalence was 648 at 34 th *** drops in late spring with people that falling ill and had had long incubation periods and rose in the summer with new *** future forecast based on the regression model was that an increase at year 2014 compared to 2013 may reach a peak(at maximum about 70 weekly cases) at year *** a decreasing trend after ***:This work shows that back-calculation methods could work well in estimating the infection rates and the prevalence of *** obtained results can be useful in establishing an efficient preventive program for malaria *** method presented here can be used in other countries where incidence data and incubation period are available.

关键词： Back calculation Incidence Incubation period Infection Poisson model Prevalence Regression model

Contemporary trends in radical prostatectomy and predictors of recovery of urinary continence in men aged over 70 years:comparisons between cohorts aged over 70 and less than 70 years

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Asian Journal of Andrology 2020年第3期22卷 280-286页

作者： Young Ju lee Jin-Woo Jung Sangchul lee Sang Wook lee jeong Hyun Kim Sung Kyu Hong Seok-Soo Byun Sang Eun lee Seong Jin jeong Departme nt of Urology Seoul National University Bundang HospitalSeongnam 13620Korea Department of Urology Catholic Kwan dong Univerisity International St.Mary's HospitalIncheon 22711Korea Department of Urology Kangwon National University School of MedicineChuncheon 24341Korea.

We evaluated contemporary trends in radical prostatectomy(RP)in men aged>70 years and investigated associations of selected variables with recovery of urinary continence(UC)in two age groups:>70 and70 years[n=610]vs70 years gradually increased up to 30.0%,and the rate of robot-assisted RP and neurovascular bundle(NVB)saving increased continually to 80.0%and 67.4%of older patients,*** the rate of recovery of UC within 12 months(3 months)in patients aged>70 years was lower than that in those aged S70 years(81.5%[52.6%]vs 88.6%[60.9%],respectively;both P70 ***,unlike younger patients,only variables(age and MUL),possibly associated with the inhere nt fun ction of the urinary sphi ncter,were predictors of recovery of UC in patients aged>70 years.

关键词： elderly predictor prostate cancer radical prostatectomy urinary incontinence

Energy efficient mechanism using flexible medium access control protocol for hybrid wireless sensor networks

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Journal of Central South University 2013年第8期20卷 2165-2174页

作者： SUN Ning jeong Yoon-su lee Sang-ho Department of Computer Science Chungbuk National University Department of Information Communication Engineering Mokwon University

Energy efficiency is a primary consideration in a wireless sensor network (WSN). This is also a major parameter when designing a medium access control (MAC) protocol for WSNs. Hierarchical clustering structure is regarded suitable for WSNs due to its good performance in energy conservation. In this work, an adequately flexible mechanism for clustering WSNs is designed, in which some creative or promotional metrics are utilized, such as cluster head selection algorithm, cluster optional reconstruction, interested data transmission, multiple path routing protocol. All these strategies were cooperated to maximize energy saving of whole system. An appropriate MAC protocol for this mechanism is proposed, by flexibly switching the status of diverse sensor nodes in different strategies. The simulation results show that the proposed MAC protocol is suitable for clustering WSNs and performs well in aspects of energy efficiency, flexibility and scalability.

关键词： MAC protocol energy conservation flexibility re-clustering wireless sensor network

Fuel combustion test in constant volume combustion chamber with built-in adaptor

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Science China(Technological Sciences) 2010年第4期53卷 1000-1007页

作者： jeong DongSoo CHO GyuBack CHOI SuJin lee JinSoo Korea Institute of Machinery & Materials

Combustion tests of pre-mixture of methane and air in constant volume combustion chamber(CVCC) have been carried out by means of flame propagation photo and gas pressure measurement,the effects of CVCC body temperature,intake pressure of pre-mixture of methane and air,equivalence ratio and location of the built-in adaptor have been *** whole combustion chamber can be divided into two parts,*** upper combustion chamber and the lower combustion chamber,by the built-in adaptor with through *** to the built-in adaptor with through hole,jet ignition or compression ignition(auto-ignition) phenomena may occur in the lower combustion chamber,which is helpful to getting higher flame propagation velocity,higher combustion peak pressure,low cycle-to-cycle variation and more stable combustion process.

关键词： constant volume combustion chamber(CVCC) built-in adaptor gas pressure measurement flame propagation photo methane

Attaching single carbon nanotube on tip's apex using dielectrophoresis of DC-pulse voltage

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中国有色金属学会会刊：英文版 2009年第B9期19卷 280-283页

作者： Hee-Jin jeong Yoong-Ho JUNG Deug-Woo lee Gyeongbuk Hybrid Technology Institute School of Mechanical Engineering Pusan National University Department of Nanosystem and Nanoprocess Engineering Pusan National University

Single carbon nanotubes (CNTs) are candidates for a number of electronics and sensing applications, provided that single CNTs can be separated from a bundle of CNTs in suspension. Dielectrophoresis has recently been demonstrated as one route for the extraction of desired CNTs. However, previous methods using dielectrophoresis have found it difficult to extract single nanotubes from bundles of CNTs in solution. Here, we show that this restriction can be overcome by using pulsed DC voltage of an electric field, instead of regular AC and DC voltages.

关键词：碳纳米管直流脉冲脉冲电压介电顶点消息电子号码 CNTs

Predictive factors for early clinical response in community-onset Escherichia coli urinary tract infection and effects of initial antibiotic treatment on early clinical response

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World Journal of Clinical Cases 2020年第19期8卷 4342-4348页

作者： Young Jun Kim jeong-Mi lee Jae-Hoon lee Department of Internal Medicine Wonkwang University College of MedicineIksan 54538South Korea Department of Public Health Wonkwang University College of MedicineIksan 54538South Korea Department of Internal Medicine and Institute of Wonkwang Medical Science Wonkwang University College of MedicineIksan 54538South Korea

BACKGROUND Urinary tract infection(UTI)is a common *** often requires hospitalization,and severe presentations,including sepsis and other complications,have a mortality rate of 6.7%-8.7%.AIM To evaluate the predictive factors for early clinical response and effects of initial antibiotic therapy on early clinical response in community-onset Escherichia coli(***)urinary tract infections(UTIs).METHODS This retrospective study was conducted at Wonkwang University Hospital in South Korea between January 2011 and December *** patients(aged>18 years)who were diagnosed with community-onset *** UTI were enrolled in this *** A total of 511 hospitalized patients were included.66.1%of the patients had an early clinical *** mean length of hospital stay in patients with an early clinical response were each 4.3 d shorter than in patients without an early clinical *** the multiple regression analysis,initial appropriate antibiotic therapy(OR=2.449,P=0.006),extended-spectrum(3-lactamase(ESBL)-producing ***(OR=2.112,P=0.044),improper use of broad-spectrum antimicrobials(OR=0.411,P=0.006),and a stay in a healthcare facility before admission(OR=0.562,P=0.033)were the factors associated with an early clinical *** broadspectrum antibiotic therapy was not associated with an early clinical *** ESBL producing ***,and the type of residence before hospital admission were the factors associated with an early clinical *** of initial antibiotic therapy was a predictive factor for an early clinical response,but broadspectrum of initial antibiotic therapy did not impact early clinical response.

关键词： Escherichia coli Urinary tract infections Adult Community acquired infections

Hexapedal Robotic Platform for Amphibious Locomotion on Ground and Water Surface

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Journal of Bionic Engineering 2016年第1期13卷 39-47页

作者： HyunGyu Kim DongGyu lee Yanheng Liu Kyungmin jeong TaeWon Seo School of Mechanical Engineering Yeungnam University Gyeongsan 712-749 Republic of Korea Nuclear Convergence Technology Div. Korea Atomic Energy Research Institute Daejeon 305-353 Republic of Korea

Bio-inspiration is a starting point from which to design engineering products by learning the secrets of living creatures. We present the design, analysis, and experimental results of a robotic platform inspired by the basilisk lizard, which is well known for its ability to run on water surface. The goal is to develop a robotic platform for amphibious locomotion on ground and water using a single configuration. A tripod gait is achieved with a hexapedal configuration and four-bar-based repeated motion of the legs. The hexapedal configuration is empirically proven to have an advantage in terms of rolling stability on water. On ground, the tripod gait can satisfy the requirements of static stability to make the center of gravity and center of pressure occur at the same position. The footpad design was determined based on an empirical study of the rolling stability and lifting force. The theoretical background and experimental results are presented to validate the ability of the proposed design to run on water and on the ground.

关键词： amphibious locomotion bio-inspiration hexapedal empirical study water-running robot

Bojungbangdocktang inhibits vascular endothelial growth factor induced angiogenesis via blocking the VEGF/VEGFR2 signaling pathway in human umbilical vein endothelial cells

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Chinese Science Bulletin 2009年第2期54卷 227-233页

作者： JANG Yu-Sung lee Eun-ok lee Hyo-Jung lee Hyo-jeong KIM Kwan-Hyun WON Sook-Hyun lee Jae-Dong AHN Kwang Seok AHN Kyoo Seok KIM Jung-Hyo YU Young-Beob KIM Sung-Hoon College of Oriental Medicine Kyunghee University 1 Hoegidong Dongdaemungu Seou1130-701 Republic of Korea Chosun Nursing College 375 Seosuk-dong Dong-gu Gwangju 501-759 Korea Department of Herbal Pharmaceutical Korea Institute of Oriental Medicine Jeonmin dong Youseonggu Daejeon 305-811 Republic of Korea

Oriental herbal medicines have been widely used for the prevention or treatment of various diseases including cancer in Asia. However, to prove their chemo preventive efficacies in modern times, scientific evidence for those herbal medicines is required. Thus, in the present study, an effective herbal cocktail Bojungbangdocktang (BJBDT) was investigated to elucidate antiangiogenic mechanism in vitro and in vivo. BJBDT significantly inhibited vascular endothelial growth factor (VEGF) induced proliferation in HUVECs at nontoxic concentrations, despite weak cytotoxicity against human umbilical vein endothelial cells (HUVECs). BJBDT also significantly suppressed VEGF-induced migration and tube formation of HUVECs. Furthermore, BJBDT treatment resulted in pale color and low hemoglobin level in Matrigel plugs, as well as dark red color and high hemoglobin level in untreated control. Interestingly, BJBDT specifically inhibited the binding of VEGF to vascular endothelial growth factor receptor 2 (VEGFR2), but not VEGFR1. In addition, friedelin, formononetin, ginsenoside Rb1, naringin, atractyloside, diosgenin, and allantonin were identified from BJBDT by high-performance liquid chromatography (HPLC) analysis as a quality of control. Taken together, these results suggest that BJBDT is a potent angiogenesis inhibitor blocking the VEGF/VEGFR2 signaling pathway in HUVECs.

关键词：血管新技术人大动脉内皮细胞 HUVECs VEGFR2

Dynamic deformation behavior and microstructural evolution during high-speed rolling of Mg alloy having non-basal texture

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Journal of Materials Science & Technology 2019年第4期35卷 473-482页

作者： Sang-Hoon Kim jeong Hun lee Chong Soo lee Jonghun Yoon Sung Hyuk Park School of Materials Science and Engineering Kyungpook National University Ulsan Regional Division Korea Institute of Industrial Technology Graduate Institute of Ferrous Technology Pohang University of Science and Technology Department of Mechanical Engineering Hanyang University

The dynamic deformation behaviors and resultant microstructural variations during high-speed rolling(HSR) of a Mg alloy with a non-basal texture are investigated. To this end, AZ31 alloy samples in which the basal poles of most grains are predominantly aligned parallel to the transverse direction(TD) are subjected to hot rolling with different reductions at a rolling speed of 470 m/min. The initial grains with a TD texture are favorable for {10–12} twinning under compression along the normal direction(ND); as a result, {10–12} twins are extensively formed in the material during HSR, and this consequently results in a drastic evolution of texture from the TD texture to the ND texture and a reduction in the grain size. After the initial grains are completely twinned by the {10–12} twinning mechanism, {10–11} contraction twins and {10–11}-{10–12} double twins are formed in the {10–12} twinned grains by further *** the contraction twins and double twins have crystallographic orientations that are favorable for basal slip during HSR, dislocations easily accumulate in these twins and fine recrystallized grains nucleate in the twins to reduce the increased internal strain energy. Until a rolling reduction of 20%, {10–12}twinning is the main mechanism governing the microstructural change during HSR, and subsequently,the microstructural evolution is dominated by the formation of contraction twins and double twins and the dynamic recrystallization in these twins. With an increase in the rolling reduction, the average grain size and internal strain energy of the high-speed-rolled(HSRed) samples decrease and the basal texture evolves from the TD texture to the ND texture more effectively. As a result, the 80% HSRed sample, which is subjected to a large strain at a high strain rate in a single rolling pass, exhibits a fully recrystallized microstructure consisting of equiaxed fine grains and has an ND basal texture without a TD texture component.

关键词： Magnesium alloy High-speed rolling Texture Dynamic recrystallization Twinning