Prostate only radiotherapy using external beam radiotherapy:A clinician’s perspective

作     者：Jeong Won Lee Mi Joo Chung 

作者机构：Department of Radiation OncologyDaegu Catholic University School of MedicineDaegu 42472South Korea Department of Radiation OncologyHanyang University Hanmaeum Changwon HospitalChangwon 51139South Korea 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2022年第10卷第29期

页      面：10428-10434页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Prostate cancer Radiotherapy Radiation dose Radiation technique Radiation volume 

摘      要：Prostate-only radiotherapy(PORT) is widely used as the definitive treatment for localized prostate *** cancer has an α/β ratio;therefore,radiotherapy(RT) with a large fraction size is biologically effective for tumor *** current external beam RT technique for PORT has been improved from threedimensional conformal RT to intensity-modulated,stereotactic body,and imageguided *** methods are associated with reduced radiation exposure to normal tissues,decreasing urinary and bowel *** trials have shown improved local control with dose escalation through the aforementioned methods,and the efficacy and safety of intensity-modulated and stereotactic body RTs have been ***,the management of RT in patients with prostate cancer has not been fully *** a clinician,there are several concerns regarding the RT volume and dose considering the patient’s age and ***,this review aimed to discuss the radiobiological basis and external beam technical advancements in PORT for localized prostate cancer from a clinician’s perspective.