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Disruption of sensation-dependent bladder emptying due to bladder overdistension in a complete spinal cord injury:A case report

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World Journal of Clinical Cases 2021年第29期9卷 8946-8952页

作者： Ju-yul Yoon Da-Sol Kim Gi-Wook Kim yu Hui Won Sung-Hee Park Myoung-Hwan Ko jeong-Hwan Seo Department of Physical Medicine and Rehabilitation Jeonbuk National University Medical SchoolJeonju 54097JeonbukSouth Korea Department of Physical Medicine and Rehabilitation Jeonbuk National University Medical SchoolKorea Research Institute of Clinical Medicine of Jeonbuk National University−Biomedical Research Institute of Jeonbuk National University HospitalJeonju 54097JeonbukSouth Korea

BACKGROUNDAutonomic dysreflexia (AD) can be a life-threatening condition in patients withspinal cord injury. It is important to prevent bladder overdistension in thesepatients as it may trigger AD. Sensation-dependent bladder emptying (SDBE), asa method of bladder management, improves the quality of life and allowsphysiologic voiding. In this study, we report disruption of the SDBE habit afterbladder overdistension leading to AD with chest *** SUMMARYA 47-year-old male with a diagnosis of C4 American Spinal Cord InjuryAssociation impairment scale A had been emptying his bladder using the cleanintermittent catheterization method with an itchy sensation in the nose as asensory indication for a full bladder for 23 years, and the usual urine volume wasabout 300-400 mL. At the time of this study, the patient had delayed catheterizationfor approximately five hours. He developed severe abdominal pain andheadache and had to visit the emergency room for bladder overdistension (800mL) and a high systolic blood pressure (205 mmHg). After control of AD, ahypersensitive bladder was observed despite using anticholinergic agents. Thesensation indicating bladder fullness changed from nose itching to pain in theabdomen and precordial area. Moreover, the volume of the painful bladder fillingsensation became highly variable and was noted when the bladder urine volumeexceeded only 100 mL. The patient refused intermittent clean catheterization Finally, a cystostomy was performed, which relieved the *** using physiologic feedback, such as SDBE, for bladder management arerecommended to avoid bladder overdistension.

关键词： Neurogenic bladder Sensation-dependent bladder emptying Spinal cord injury Autonomic dysreflexia Bladder overdistension Bladder management Case report

Population trend and spatio-temporal distribution of Greater White-fronted(Anser albifrons)and Bean Geese(Anser fabalis)in Korea

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Avian Research 2024年第4期15卷 458-465页

作者： Eun-jeong Kim Wee-Heang Hur Hwa-Jung Kim yu-Seong Choi Dongwon Kim Who-Seung Lee Sejeong Han Hyerin Joo Chang-Yong Choi Department of Agriculture Forestryand BioresourcesSeoul National UniversitySeoul08826Republic of Korea Research Institute of Agriculture and Life Science Seoul National UniversitySeoul08826Republic of Korea National Migratory Birds Center National Institute of Biological ResourcesIncheon22689Republic of Korea Division for Natural Environment Korea Environment InstituteSejong30147Republic of Korea

Geese have undergone significant changes in their distribution and population size due to human-induced *** improve our understanding of the two main geese populations in East Asia—Greater White-fronted(Anser albifrons;GWFG)and Bean Geese(Anser fabalis sensu lato;BEAG),which includes the Tundra ***(TDBG)and Taiga Bean Geese ***(TGBG),this study estimated their long-and short-term trends and the migration strategies based on their distribution during the migratory and wintering seasons,using nationwide census data collected over 24 years in South *** TRIM(TRends and Indices for Monitoring data)analysis supported a robust long-term population increase since 1999,recently stabilizing around 150,000 individuals in GWFG and 100,000 in TDBG,*** TGBG stabilized at around 7000 with no significant change of population over *** shorter-term trends within a season suggested that wintering populations of GWFG and TDBG in China might stop over in Korea in their autumn migration before their sea-crossing,evidenced by the large congregation near the Yellow Sea coast followed by a gradual *** contrast to autumn,there was no similar peak in spring migration,suggesting the potential for elliptical migration of some populations around the Yellow *** findings indicate a growing East Asian population and imply one of the migration strategies of the Greater White-fronted and Tundra Bean *** collaborating with recent tracking data,long-term monitoring efforts could offer more detailed insights into population trends and migration strategies,thereby contributing to the effective management and conservation of goose species in East Asia.

关键词： Bean Goose Anser fabalis East Asia Greater White-fronted Goose Anser albifrons Long-term monitoring Spatiotemporal distribution Non-breeding

Fully tunable Fabry-Pérot cavity based on MEMS Sagnac loop reflector with ultra-low static power consumption

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Microsystems & Nanoengineering 2024年第4期10卷 355-365页

作者： Young Jae Park Man Jae Her Youngjae jeong Dong Ju Choi Dong Uk Kim Min Gi Lim Myung Seok Hong Hyug Su Kwon Kyoungsik yu Sangyoon Han Department of Robotics and Mechatronics Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)Daegu 42988Republic of Korea School of Electrical Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Agency for Defense Development DaejeonRepublic of Korea

The Fabry-Pérot interferometer,a fundamental component in optoelectronic systems,offers interesting applications such as sensors,lasers,and *** this work,we show a tunable Fabry-Pérot cavity consisting of tunable Sagnac loop reflectors(SLRs)and phase shifters based on electrostatic microelectromechanical(MEMS)*** fabrication process of the device is compatible with the standard wafer-level silicon photonics fabrication *** electrostatic actuation mechanism provides well-balanced,scalable pathways for efficient tuning *** extinction ratio of the continuously tunable SLRs’reflectivity is larger than 20 *** 2πphase shifting is achieved,and response times of all the components are less than 25μ*** actuators have extremely low static power,measuring under 20 fW and the energy needed for tuning is both below 20 pJ.

关键词： tunable tuning interferometer

Biliary phytobezoar resulting in intestinal obstruction

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World Journal of Gastroenterology 2013年第1期19卷 133-136页

作者： yura Kim Beom Jin Park Min Ju Kim Deuk Jae Sung Dong-Sik Kim Young-Dong yu jeong Hyeon Lee Department of Radiology College of MedicineKorea UniversityAnam HospitalSeoul 136-705South Korea Division of HBP Surgery and Liver Transplantation Department of SurgeryCollege of MedicineKorea UniversityAnam HospitalSeoul 136-705South Korea Department of Pathology College of MedicineKorea UniversityAnam HospitalSeoul 136-705South Korea

Phytobezoar is the most common type of *** is composed of indigestible vegetable matter and is usually found in the *** phytobezoar is extremely rare and difficult to diagnose *** pathogenesis is not clear,and there have been only a few reports of biliary bezoars associated with sphincteric impairmentat the ampulla of ***,we present a report of biliary bezoar that resulted in jejunal *** were unable to identifythe bezoar in the extrahepatic bile duct until it obstructed the small bowel *** our knowledge,this is the first report of small bowel obstruction resulting frommigration of a biliary bezoar.

关键词： Phytobezoar Biliary Intestinal obstruction Choledochoduodenal Fistula Multidetector-row computed tomography

Novel fabrication techniques for ultra-thin silicon based flexible electronics

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International Journal of Extreme Manufacturing 2024年第4期6卷 116-149页

作者： Ju Young Lee jeong Eun Ju Chanwoo Lee Sang Min Won Ki Jun yu School of Electrical and Electronic Engineering Yonsei University50 Yonsei-roSeodaemunguSeoul 03722Republic of Korea Department of Electrical and Computer Engineering Sungkyunkwan UniversitySuwon 16419Republic of Korea yu-Korea Institute of Science and Technology(KIST)Institute Yonsei University50Yonsei-roSeodaemun-guSeoul 03722Republic of Korea

Flexible electronics offer a multitude of advantages,such as flexibility,lightweight property,portability,and high *** unique properties allow for seamless applications to curved and soft surfaces,leading to extensive utilization across a wide range of fields in consumer *** applications,for example,span integrated circuits,solar cells,batteries,wearable devices,bio-implants,soft robotics,and biomimetic ***,flexible electronic devices have been developed using a variety of materials such as organic,carbon-based,and inorganic semiconducting ***(Si)owing to its mature fabrication process,excellent electrical,optical,thermal properties,and cost efficiency,remains a compelling material choice for flexible ***,the research on ultra-thin Si in the context of flexible electronics is studied rigorously *** thinning of Si is crucially important for flexible electronics as it reduces its bending stiffness and the resultant bending strain,thereby enhancing flexibility while preserving its exceptional *** review provides a comprehensive overview of the recent efforts in the fabrication techniques for forming ultra-thin Si using top-down and bottom-up approaches and explores their utilization in flexible electronics and their applications.

关键词： flexible electronics silicon fabrication technique top-down approach bottom-up approach

Technical Analysis of VTOL UAV

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Journal of Computer and Communications 2016年第15期4卷 92-97页

作者： Seunghee yu Jinyeong Heo Sekyung jeong Yongjin Kwon Department of Industrial Engineering Ajou University Suwon South Korea

Overall, this paper explains the related information about VTOL and trend of this technology worldwide. Also, it comes up with the distinction among VTOL and helicopter and fixed wing aircraft. This paper concentrates on domestic and international drones that utilize VTOL technology. Also, this paper gives the explanation about VTOL’s performance and object. Furthermore, this paper predicts the future of VTOL and which area this technology going to be used.

关键词： VTOL UAV Tilt-Rotor Multicopter Military

Gut microbiome composition can predict the response to nivolumab in advanced hepatocellular carcinoma patients

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World Journal of Gastroenterology 2021年第42期27卷 7340-7349页

作者： Min-Woo Chung Moon-Ju Kim Eun jeong Won yu jeong Lee Yong-Woon yun Sung Bum Cho Young-Eun Joo Jun-Eul Hwang Woo Kyun Bae Ik-Joo Chung Myung Geun Shin Jong Hee Shin Department of Internal Medicine Chonnam National University Hospital and College of MedicineHwasun 58128Jeollanam-doSouth Korea Department of Parasitology and Tropical Medicine Chonnam National University Medical SchoolHwasun 58128Jeollanam-doSouth Korea Department of Laboratory Medicine Chonnam National University Hwasun HospitalHwasun 58128Jeollanam-doSouth Korea Department of Preventive Medicine Chonnam National University Medical SchoolHwasun-eupHwasun 58128Jeollanam-doSouth Korea Department of Laboratory Medicine Chonnam National University HospitalGwangju 61469South Korea

BACKGROUND Immunotherapy has revolutionized the clinical outcomes of intractable cancer *** is known about the intestinal nonpathogenic bacterial composition of hepatocellular carcinoma(HCC)patients treated by *** To determine whether there is a correlation between gut bacterial composition and prognosis in HCC *** From September 2019 to March 2020,we prospectively collected fecal samples and examined the gut microbiome of 8 advanced HCC patients treated with nivolumab as a second-or third-line systemic *** samples were collected before the start of *** samples of patients with progression during treatment were collected at the time of progression,and fecal samples of patients who showed good response to nivolumab were collected after 5-7 mo as *** data from 16S ribosomal RNA sequencing were analyzed using CLC Genomics *** data were analyzed according to therapeutic *** All 8 patients were male,of which 6 had underlying chronic hepatitis B.A higher Shannon index was found in the responders than in the non-responders after nivolumab therapy(P=0.036).The unweighted beta diversity analysis also showed that the overall bacterial community structure and phylogenetic diversity were clearly distinguished according to therapeutic *** was no significant difference in the diversity or composition of the patient gut microbiome according to the immunotherapy *** taxa specific to therapeutic response were designated as follows:Dialister pneumosintes,Escherichia coli,Lactobacillus reteri,Streptococcus mutans,Enterococcus faecium,Streptococcus gordonii,Veillonella atypica,Granulicatella sp.,and Trchuris trichiura for the nonresponders;Citrobacter freundii,Azospirillum *** Enterococcus durans for the *** note,a skewed Firmicutes/Bacteroidetes ratio and a low Prevotella/Bacteroides ratio can serve as predictive markers of non-response,wh

关键词： Microbiome Nivolumab Firmicutes/Bacteroidetes ratio Prevotella/Bacteroides ratio Hepatocellular carcinoma Prognosis

Genomic change in hepatitis B virus associated with development of hepatocellular carcinoma

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World Journal of Gastroenterology 2016年第23期22卷 5393-5399页

作者： Danbi Lee Heather Lyu Young-Hwa Chung jeong A Kim Priya Mathews Elizabeth Jaffee Lei Zheng Eunsil yu Young Joo Lee Soo Hyung Ryu Department of Internal Medicine University of Ulsan College of MedicineAsan Medical Center Sidney Kimmel Comprehensive Cancer Center Johns Hopkins University School of MedicineBaltimore Department of Pathology University of Ulsan College of MedicineAsan Medical Center Department of Hepatobiliary Surgery University of Ulsan College of MedicineAsan Medical Center Department of Internal Medicine Inje Uni-versity College of MedicineSeoul Paik Hospital

AIM: To determine the genomic changes in hepatitis B virus(HBV) and evaluate their role in the development of hepatocellular carcinoma(HCC) in patients chronically infected with genotype C ***: Two hundred and forty chronic hepatitis B(CHB) patients were subjected and followed for a median of 105 mo. HCC was diagnosed in accordance with AASLD guidelines. The whole X, S, basal core promoter(BCP), and precore regions of HBV were sequenced using the direct sequencing ***: All of the subjects were infected with genotype C HBV. Out of 240 CHB patients, 25(10%) had C1653 T and 33(14%) had T1753 V mutation in X region; 157(65%) had A1762T/G1764 A mutations in BCP region, 50(21%) had G1896 A mutation in precore region and 67(28%) had pre-S deletions. HCC occurred in 6 patients(3%). The prevalence of T1753 V mutation was significantly higher in patients who developed HCC than in those without HCC. The cumulative occurrence rates of HCC were 5% and 19% at 10 and 15 years, respectively, in patients with T1753 V mutant, which were significantly higher than 1% and 1% in those with wild type HBV(P < 0.001).CONCLUSION: The presence of T1753 V mutation in HBV X-gene significantly increases the risk of HCC development in patients chronically infected with genotype C HBV.

关键词： Hepatocellular carcinoma Chronic hepatitis B Genomic change Hepatitis B virus Genotype C

Seroprevalence of Severe Fever with Thrombocytopenia Syndrome Phlebovirus in Domesticated Deer in South Korea

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Virologica Sinica 2019年第5期34卷 501-507页

作者： Min-Ah yu Kwang-Min yu Su-Jin Park Young-ll Kim Norbert John Robles Young-Jae Si Eun-Ha Kim Hyeok-ll Kwon Hye Won jeong Min-Suk Song Seok-Yong Kim Young Ki Choi Department of Microbiology College of Medicine and Medical Research InstituteChungbuk National UniversityCheongju 28644Republic of Korea Zoonotic Infectious Diseases Research Center Chungbuk National UniversityCheongju 28644Republic of Korea Department of Internal Medicine College of Medicine and Medical Research InstituteCheongju 28644Republic of Korea Department of Internal Medicine Chungbuk National University HospitalCheongju 28644Republic of Korea

Severe fever with thrombocytopenia syndrome phlebovirus(SFTSV)has a wide host *** only has it been found in humans,but also in many wild and domesticated *** infection of breeding deer on farms is a particularly worrisome public health concern due to the large amount of human contact and the diverse use of deer products,including raw *** investigate the prevalence of breeding domesticated deer,we examined the SFTSV infection rate on deer farms in South Korea from 2015 to *** the 215 collected blood samples,0.9%(2/215)were found to be positive for viral RNA by PCR,and sequence analysis showed the highest homology with the KADGH human *** SFTSVspecific recombinant N and Gn protein-based ELIS As revealed that 14.0%(30/215)and 7.9%(17/215)of collected blood specimens were positive for SFTSV *** results demonstrate that the breeding farm deer are exposed to SFTSV and could be a potential infection source for humans through direct contact or consumption of byproducts.

关键词： Severe fever with thrombocytopenia syndrome phlebovirus(SFTSV) Breeding deer•Seroprevalence South Korea