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Evaluation and Prediction of Groundwater Quality in the Municipality of Za-Kpota (South Benin) Using Machine Learning and Remote Sensing

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Journal of Water Resource and Protection 2024年第7期16卷 502-522页

作者： jennifer A. Ahlonsou Firmin M. Adandedji Abdoukarim Alassane Consolas Adihou Mama Daouda Laboratoire dHydrologie Applique (LHA) Institut National de lEau (INE) University of Abomey-Calavi (UAC) Abomey-Calavi Benin Centre dExcellence dAfrique pour lEau et lAssainissement (C2EA) University of Abomey-Calavi (UAC) Abomey-Calavi Benin Department of Water Directorate of Zou Water Service Bohicon Benin

Accessing drinking water is a global issue. This study aims to contribute to the assessment of groundwater quality in the municipality of Za-Kpota (southern Benin) using remote sensing and Machine Learning. The methodological approach used consisted in linking groundwater physico-chemical parameter data collected in the field and in the laboratory using AFNOR 1994 standardized methods to satellite data (Landsat) in order to sketch out a groundwater quality prediction model. The data was processed using QGis (Semi-Automatic Plugin: SCP) and Python (Jupyter Netebook: Prediction) softwares. The results of water analysis from the sampled wells and boreholes indicated that most of the water is acidic (pH varying between 5.59 and 7.83). The water was moderately mineralized, with conductivity values of less than 1500 μs/cm overall (59 µS/cm to 1344 µS/cm), with high concentrations of nitrates and phosphates in places. The dynamics of groundwater quality in the municipality of Za-Kpota between 2008 and 2022 are also marked by a regression in land use units (a regression in vegetation and marshland formation in favor of built-up areas, bare soil, crops and fallow land) revealed by the diachronic analysis of satellite images from 2008, 2013, 2018 and 2022. Surveys of local residents revealed the use of herbicides and pesticides in agricultural fields, which are the main drivers contributing to the groundwater quality deterioration observed in the study area. Field surveys revealed the use of herbicides and pesticides in agricultural fields, which are factors contributing to the deterioration in groundwater quality observed in the study area. The results of the groundwater quality prediction models (ANN, RF and LR) developed led to the conclusion that the model based on Artificial Neural Networks (ANN: R2 = 0.97 and RMSE = 0) is the best for groundwater quality changes modelling in the Za-Kpota municipality.

关键词： Groundwater Land Use Electrical Conductivity Machine Learning Za-Kpota

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A rat model of multicompartmental traumatic injury and hemorrhagic shock induces bone marrow dysfunction and profound anemia

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Animal Models and Experimental Medicine 2024年第3期7卷 367-376页

作者： Lauren S.Kelly jennifer A.Munley Erick E.Pons Kolenkode B.Kannan Elizabeth M.Whitley Letitia E.Bible Philip A.Efron Alicia M.Mohr Department of Surgery and Sepsis and Critical Illness Research Center University of Florida College of MedicineGainesvilleFloridaUSA Pathogenesis LLCGainesvilleFloridaUSA

Background:Severe trauma is associated with systemic inflammation and organ *** rodent trauma models are the mainstay of postinjury research but have been criticized for not fully replicating severe human *** aim of this study was to create a rat model of multicompartmental injury which recreates profound traumatic ***:Male Sprague-Dawley rats were subjected to unilateral lung contusion and hemorrhagic shock(LCHS),multicompartmental polytrauma(PT)(unilateral lung contusion,hemorrhagic shock,cecectomy,bifemoral pseudofracture),or na?ve ***,plasma toll-l ike receptor 4(TLR4),hemoglobin,spleen to body weight ratio,bone marrow(BM)erythroid progenitor(CFU-GEMM,BFU-E,and CFU-E)growth,plasma granulocyte colony-stimulating factor(G-CSF)and right lung histologic injury were assessed on day 7,with significance defined as p values<0.05(*).Results:Polytrauma resulted in markedly more profound inhibition of weight gain compared to LCHS(p=0.0002)along with elevated plasma TLR4(p<0.0001),lower hemoglobin(p<0.0001),and enlarged spleen to body weight ratios(p=0.004).Both LCHS and PT demonstrated suppression of CFU-E and BFU-E growth compared to naive(p<0.03,p<0.01).Plasma G-CSF was elevated in PT compared to both na?ve and LCHS(p<0.0001,p=0.02).LCHS and PT demonstrated significant histologic right lung injury with poor alveolar wall integrity and interstitial ***:Multicompartmental injury as described here establishes a reproducible model of multicompartmental injury with worsened anemia,splenic tissue enlargement,weight loss,and increased inflammatory activity compared to a less severe *** may serve as a more effective model to recreate profound traumatic injury to replicate the human inflammatory response postinjury.

关键词： anemia i nflammation polytrauma pseudofracture shock

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Evaluating the Efficacy of Cervical Tactile Ultrasound Technique as a Predictive Tool for Spontaneous Preterm Birth

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Open Journal of Obstetrics and Gynecology 2024年第5期14卷 832-846页

作者： Vladimir Egorov Todd Rosen jennifer Hill Meena Khandelwal Victors Kurtenoks Brendan Francy Noune Sarvazyan Advanced Tactile Imaging Inc. Ewing New Jersey USA Department of Obstetrics Gynecology and Reproductive Sciences Rutgers Robert Wood Johnson Medical School New Brunswick New Jersey USA Department of Maternal-Fetal Medicine Cooper Medical School of Rowan University Camden New Jersey USA

Background: Premature cervical softening and shortening may be considered an early mechanical failure that predispose to preterm birth. Purpose: This study aims to explore the applicability of an innovative cervical tactile ultrasound approach for predicting spontaneous preterm birth (sPTB). Materials and Methods: Eligible participants were women with low-risk singleton pregnancies in their second trimester, enrolled in this prospective observational study. A Cervix Monitor (CM) device was designed with a vaginal probe comprising four tactile sensors and a single ultrasound transducer operating at 5 MHz. The probe enabled the application of controllable pressure to the external cervical surface, facilitating the acquisition of stress-strain data from both anterior and posterior cervical sectors. Gestational age at delivery was recorded and compared against cervical elasticity. Results: CM examination data were analyzed for 127 women at 240/7 - 286/7 gestational weeks. sPTB was observed in 6.3% of the cases. The preterm group exhibited a lower average cervical stress-to-strain ratio (elasticity) of 0.70 ± 0.26 kPa/mm compared to the term group’s 1.63 ± 0.65 kPa/mm with a p-value of 1.1 × 10−4. Diagnostic accuracy for predicting spontaneous preterm birth based solely on cervical elasticity data was found to be 95.0% (95% CI, 88.5 - 100.0). Conclusion: These findings suggest that measuring cervical elasticity with the designed tactile ultrasound probe has the potential to predict spontaneous preterm birth in a cost-effective manner.

关键词： Cervical Elasticity Spontaneous Preterm Birth Tactile Ultrasound Probe

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氢安全建模研究进展

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化工进展 2024年

作者：程崇律单聪慧张孟凡 WEN X jennifer 徐宝鹏萨里大学可持续发展研究所大连理工大学能源与动力学院

氢能对于实现国家“双碳”目标至关重要。由于氢气独特的性质，在储存、运输和使用过程中极易发生泄漏，从而引发严重的安全事故，这成为制约氢能源大规模应用的主要障碍之一。为了更好地应对氢能利用过程中的安全挑战，开展风险研究至... 详细信息

氢能对于实现国家“双碳”目标至关重要。由于氢气独特的性质，在储存、运输和使用过程中极易发生泄漏，从而引发严重的安全事故，这成为制约氢能源大规模应用的主要障碍之一。为了更好地应对氢能利用过程中的安全挑战，开展风险研究至关重要。本文简要介绍了氢气的基本理化特性，讨论了氢气和液氢泄漏、扩散、射流火焰以及爆炸的建模方法，总结了氢气和液氢在泄漏、扩散、射流燃烧和爆炸等过程中的演化规律以及内在机理，深入分析了影响上述过程的多种关键因素，例如气体种类、储存条件、泄漏条件、环境条件和通风条件等，重点关注了CFD方法在当前研究中的应用；指出了当前研究的不足之处，并就未来的发展方向提出建议。对于促进氢能安全研究、完善事故预防和应急响应机制具有重要指导意义。

关键词：氢泄漏扩散燃烧爆炸数值模拟

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Risk scores for allograft failure: Are they still useful in liver recipients from donation after circulatory death?

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World Journal of Transplantation 2024年第4期14卷 95-100页

作者： Mohamed H Mohamed Chairi Mónica Mogollón González jennifer Triguero Cabrera Inmaculada Segura Jiménez Maria T Villegas Herrera Jesús M Villar del Moral Transplant Surgery Division Department of SurgeryVirgen de las Nieves University HospitalGranada 18013AndalusiaSpain

BACKGROUND Liver grafts from donation after circulatory death(DCD)are associated with a higher risk of early graft dysfunction,determined by the warm ischemia and cold ischemia *** is essential to have precise criteria to identify this complication in order to guide therapeutic *** To validate different graft and recipient survival scores in patients undergoing liver transplantation(LT)with DCD *** A retrospective and observational unicentric study was conducted on 65 LT patients with grafts obtained from controlled DCD donors from November 2013 to November *** United Kingdom(UK)risk score,early allograft dysfunction(EAD)Olthoff score,and model for early allograft function(MEAF)score were used to evaluate the risk of graft and recipient survival *** survival analysis purposes,we used the Kaplan-Meier method,and the differences between subgroups were compared using the log-rank(Mantel-Cox)*** Sixty-five patients were included in the *** UK risk score did not demonstrate predictive capacity for recipient or graft ***,in donors aged over 70 years old(18.4%),it significantly predicted graft survival(P<0.05).According to Kaplan-Meier survival curves,graft survival rates at 6 months,2 years,and 5 years in the futility group dramatically decreased to 50%compared to the other groups(log-rank 8.806,P<0.05).The EAD Olthoff and MEAF scores did not demonstrate predictive capacity for recipient or graft *** on Kaplan-Meier survival curves,patients with a MEAF score≥7 had a lower graft survival rate at 6 months,2 years,and 5 years compared to patients with a lower MEAF score(log-rank 4.667,P<0.05).CONCLUSION In our series,both UK DCD risk score and MEAF score showed predictive capability for graft survival.

关键词： Liver transplantation Donation after circulatory death Early allograft dysfunction Risk scores Graft surviva

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Shenqi Fuzheng injection alleviates chemotherapy-induced cachexia by restoring glucocorticoid signaling in hypothalamus

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Journal of Pharmaceutical Analysis 2024年第3期14卷 431-434页

作者： Entezar Berik Zijia Zhang Wei Li Yawen Liu Sihan Chen Wenyong Wu Zhaojun Wang Xinqin Kong Wenqiang Pei Huiqing Dong Huali Long Min Lei jennifer Yiyang Wang Liangfeng Liu Jinjun Hou Jing Feng Zhaoxia Li Wanying Wu De-an Guo Beijing Key Lab of TCM Collateral Disease Theory Research School of Traditional Chinese MedicineCapital Medical UniversityBeijing100069China National Engineering Research Center of TCM Standardization Technology Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai201203China University of Chinese Academy of Sciences Beijing100049China School of Chinese Materia Medica Nanjing University of Chinese MedicineNanjing210029China Limin Pharmaceutical Factory Livzon Group LimitedShaoguanGuangdong512028China Guangdong Corporate Key Laboratory of High-End Liquid Medicine R&D IndustrilizationShaoguanGuangdong512028China Center for Neurological and Psychiatric Research and Drug Discovery Shanghai Institute of Materia MedicaChinese Academy of ScienceShanghai201203China

Chemotherapy-induced cachexia(CIC)is a debilitating condition characterized by weight loss,muscle atrophy,and anorexia[1].While peripheral mechanisms of cachexia have been extensively studied,the involvement of the central nervous system(CNS)in CIC is often *** drugs cause stress responses and inflammation,which may impact the hypothalamus and disrupt systemic energy and neuroendocrine *** hypothalamic roles in regulating these processes can provide insights into CIC's mechanisms and aid in developing novel therapies.

关键词： injection drugs glucocorticoid chemotherapy

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四条腿的天使

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中学生英语 2024年第27期 26-28页

作者： jennifer Crites 张宁

Surrounded by rolling green hills dotted1with horses and cows,the beautiful ranch town of Waimea on Hawaii's Big Island is a peaceful and friendly *** afternoon,while staying with friends at their house there,my husband and I decided to go for a walk along the many,mostly traffic-free,country lanes2in the area.夏威夷大岛上风景如画的牧场小镇威美亚镇被连绵起伏的青山环绕,其间散布着马匹和奶牛,是一个宁静友好的地方。住在那里朋友的家里期间,一天下午,我和丈夫决定沿着该地区许多几乎没有车辆通行的乡村小路散步。

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A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： Simeon C.Daeschler Katelyn J.W.So Konstantin Feinberg Marina Manoraj Jenny Cheung jennifer Zhang Kaveh Mirmoeini JPaul Santerre Tessa Gordon Gregory HBorschel SickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University School of Medicine IndianapolisINUSA Division of Plastic and Reconstructive Surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

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Wernicke-Korsakoff Syndrome From Hyperemesis Gravidarum

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Maternal-Fetal Medicine 2024年第1期6卷 54-56页

作者： Vaishnavi Jagat Patel jennifer Vu Gisela Mercado Sreenivas Avula Shad Deering University of the Incarnate Word School of Osteopathic Medicine San AntonioTX 78235USA Department of Pediatrics Children’s Hospital of San AntonioSan AntonioTX 78207USA Baylor College of Medicine HoustonTX 77030USA Department of Radiology Children’s Hospital of San AntonioSan AntonioTX 78207USA Department of Radiology Baylor College of MedicineHoustonTX 77030USA Department of OB/GYN Children’s Hospital of San AntonioSan AntonioTX 78207USA Department of OB/GYN Baylor College of MedicineHoustonTX 77030USA

To editor:Wernicke encephalopathy(WE)is an acute neurological disorder caused by a deficiency of vitamin B1(thiamine),with a prevalence of 1.3%in autopsy studies.1 Eighty-four percent of patients with WE will develop Korsakoff syndrome,which is characterized by amnesia and confusion.2 Although WE is more common in alcoholics,it can also be caused by vomiting,malnourishment,and other situations.

关键词： Hyperemesis gravidarum Wernicke's encephalopathy Pregnancy complication Wernicke-korsakoff

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Anal cancer screening in women with a history of human papillomavirusrelated lower genital tract cancers:a pilot study

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Gynecology and Obstetrics Clinical Medicine 2024年第2期4卷 88-93页

作者： Isobel Mary Poynten Fengyi Jin Rhonda Farrell Trevor Tejada-Berges Carmella Law Richard Hillman jennifer Roberts Andrew Grulich The Kirby Institute University of New South WalesSydneyNew South WalesAustralia Chris O'Brien Lifehouse SydneyNew South WalesAustralia Prince of Wales Private Hospital RandwickNew South WalesAustralia Dysplasia and Anal Cancer Services St Vincent's Hospital SydneyDarlinghurstNewSouthWalesAustralia Douglass Hanly Moir Pathology SydneyNew South WalesAustralia

Objectives Women diagnosed with a history of lower genital tract cancer(LGTC)and precancer are at increased risk of anal *** for anal cancer in a manner analogous to cervical cancer may detect precursor anal high-grade squamous intraepithelial lesions(HSILs)and prevent progression to *** In a pilot study of anal cancer screening,women with previous LGTC and aged≥18 years in Sydney,Australia underwent a digital anorectal examination,anal swab for human papillomavirus(HPV)and p16/Ki67 testing and completeda *** with positive HPV and/or p16/Ki67 results were referred for a high-resolution anoscopy(HRA)and evaluation of their *** Of 52 participants,46 agreed to screening and 6 provided demographic information *** age was 46.5 years(IQR:36.059.0).Anal high-risk HPV(HRHPV)was detected in only seven(15.2%)participants(three HPV16).Eight(17.4%)had positive p16/Ki67 dual staining,with invalid results for 25(54.4%).0f 10 women referred for HRA,9 attended and 3 had HSILs,representing 6.5%of the screened *** were completed by 41 participants(89.1%).The majority reported that being screenedwas reassuring(97.5%)and was positive for their health(95.1%).Conclusion This pilot study demonstrated a lower-than-expected prevalence of anal *** with HRHPV and p16/Ki67 staining identified anal HSILs in 6.5%of ***,screeningwas viewed as beneficial by almost all *** utility of p16/Ki67dual staining was low,suggesting it may not be a suitable anal cancer screening methodology.

关键词： pilot Sydney screening

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