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Morphology-based classif.ation of.the f.ing capacities of.aquatic insects: A f.st attempt

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Current Zoology 2024年第5期70卷 607-617页

作者： Rémi Gerber Christophe Piscart jean-Marc Roussel Benjamin Bergerot University of.Rennes CNRSECOBIO UMR 6553F-35042 RennesFrance DECOD(Ecosystem Dynamics and Sustainability) INRAEInstitut AgroIFREMERRennesFrance

f.ight is a key f.ature of.the reproduction and dispersal of.emerging aquatic ***,morphological measurements of.insect f.ght are mostly available f.r terrestrial taxa and dragonf.es,while aquatic insects have been poorly *** analyzed 7 f.ght-related morphological parameters of.32 taxa belonging to 5 orders of.emerging aquatic insects(Ephemeroptera,Trichoptera,Plecoptera,Diptera,and Megaloptera)with dif.erent lif. history traits related to f.ght(dispersal strategy,voltinism,adult lif.span,and swarming behavior).Af.er correcting f.r allometry,we used an a priori-f.ee approach to cluster the individuals according to their f.ght-related ***,we explored the levels of.agreement between these clusters,taxonomy,and several lif. history traits of.the *** orders were scattered among several clusters,suggesting a large range of.f.ght capacities,particularly f.r *** f.und swarming taxa in each cluster,showing that morphological adaptations to swarming are not identical in all aquatic *** clusters did not match the expected dispersal capacity of.the taxa as derived f.om the literature or *** wide-winged insects notably gathered taxa traditionally described as good or weak *** capacities based on morphology partly matched with the taxonomy and lif.-history traits of.aquatic insect *** parameters such as f.ght propensity,energy stores,and wing kinematics should help ref.e their f.ing and dispersal capacity.

关键词： allometry dispersal f.ght f.eshwater wing

Bioef.icacy of.Plectranthus kirbii Powder and Extracts on Stored Cowpea Pest Callosobruchus maculatus (Coleoptera: Chrysomelidae)

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Advances in Entomology 2022年第3期10卷 205-222页

作者： jean Wini Goudoungou f.licité Arindo Katamssadan Haman Tof.l Raoul Barry Borkeum jean Pierre Abdou Elias Nchiwan Nukenine Department of.Biological Sciences Faculty of Science University of Bamenda Cameroon Department of.Biological Sciences Faculty of Science University of Ngaoundere Cameroon Department of.Lif. Sciences Higher Teacher Training College of Bertoua University of Ngaoundere Cameroon Department of.Chemistry Faculty of Science University of Ngaoundere Cameroon

Cowpea seed constitutes an important source of.proteins f.r populations in Sub-Saharan Af.ica. But this f.od resource is heavily damaged by cowpea beetle Callosobruchus maculatus. The control of.that pest is mainly carried out by using synthetic insecticides. Despite the ef.icacy of.this method, it caused environmental and health problems. Theref.re, the search f.r alternative methods is vivaciously needed. In this issue, the bio-ef.icacy of.Plectranthus kirbii extracts was assessed on C. maculatus regarding adult mortality, suppression of.population and grain damage as well as seed viability preservation and repellency. The leaf.powder and aqueous extracts of.the plant were tested at 2, 4, 8 and 16 g/kg on bruchid adult f.r toxicity and damage bioassays. Repellency test was carried out using the plant aqueous, methanolic and ethyl acetate extracts at 0.5, 1, 2 and 4 mg/cm2. The seed viability was evaluated using seeds preserved f.r three months at the single concentration of.16 g/kg of.each plant extract. Signif.cant mortality of.cowpea beetle was induced by the plant aqueous extract and leaf.powder. LC50 values decreased with the increasing exposure period, and aqueous extract and leaf.powder recorded 33.42 and 9.48 g/kg respectively within 3 days whereas within 5 days, the same extracts in the same order recorded LC50 of.1.31 and 8.73 g/kg respectively. These extracts signif.cantly reduced damage by suppressing almost completely the bruchid population growth. The non-inf.sted grain preserved recorded high grain viability compared to the inf.sted ones. The non-treated inf.sted recorded the lowest germination rate (11.33%). The repellency rate ranged f.om 38.75% to 83.75%. Ethyl acetate and methanolic extracts were classif.ed as the class III repellent product, while aqueous extract ranged as class IV in repellency. Considering these f.ndings, the extracts of.P. kirbii could f.vourably replace the synthetic insecticides used in the

关键词： Cowpea Beetle Plant Extracts Mortality Damage Viability

Three Dif.erent f.nctional Microdomains in the Hepatitis C Virus Hypervariable Region 1(HVR1 ) Mediate Entry and Immune evasion

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Three Different Functional Microdomains in the Hepatitis C V...

The use of.poly(styrene-block-isobutyleneblock-styrene)as a microshunt to treat glaucoma

2012全国临床微生物与感染免疫学术研讨会

作者： jean Dubuisson Thomas f.Baumert Laure Aurelian 里尔大学巴斯德研究所感染与免疫中心斯特拉斯堡大学马里兰大学医学院药理与实验药物治疗研究室

High genetic heterogeneity is an important characteristic of.Hepatitis C virus(HCV) that contributes to its ability to establish persistent *** hypervariable region 1(HVR1) that comprises the f.rst 27 amino acid residues of.the E2 envelope glycoprotein is the most variable region within the HCV *** plays a major role in both HCV cell entry and immune evasion,but the respective contribution of.specif.c amino acid residues is still *** mutagenesis analyses of.HCV pseudoparticles(HCVpp) and cell culture-derived HCV (HCVcc) using the H77 isolate indicate that f.ve residues at positions 14,15 and 25-27 mediate binding of.the

关键词： Hepatitis C Virus Hype rvariable Region 1 Virus entry Immune evasion

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Regenerative Biomaterials 2016年第2期3卷 137-142页

作者： Leonard Pinchuk Isabelle Riss Juan f.Batlle Yasushi P.Kato John B.Martin Esdras Arrieta Paul Palmberg Richard K.Parrish Bruce A.Weber Yongmoon Kwon jean-Marie Parel Innf.cus Inc.MiamiFLUSA Ophthalmic Biophysics Center Bascom Palmer Eye InstituteUniversity of Miami Miller School of MedicineMiamiFLUSA Pôle Ophtalmologique De La Clinique Mutualiste Pessac CedexFrance Centro Laser Santo DomingoDominican Republic Anne Bates Leach Eye Hospital University of MiamiBascom Palmer Eye InstituteMiller School of MedicineMiamiFLUSA Department of.Ophthalmology University of Paris Hotel-Dieu HospitalParisFrance

The Innf.cus MicroShuntVR is a minimally invasive glaucoma drainage microtube used to shunt aqueous humor f.om the anterior chamber of.the eye to a f.ap f.rmed under the conjunctiva and Tenon’s *** saf.ty and clinical perf.rmance of.this device approaches that of.trabeculectomy with mitomycin C,the current‘gold standard’treatment f.r advanced *** invention of.a new biomaterial called poly(styrene-block-isobutylene-block-styrene)or‘SIBS’is the enabling f.ctor which led to the success of.this *** is ultrastable with virtually no f.reign body reaction in the body,which manif.sts as clinically insignif.cant inf.ammation and capsule f.rmation in the *** lack of.capsule f.rmation enables unobstructed f.ow through the 70 mm lumen tube and the achievement of.controlled low intraocular pressure,which is important f.r the management of.*** article summarizes the integration of.SIBS into a glaucoma drainage device and conf.rms its f.nctionality with clinical success over a 2-year period.

关键词： biocompatibility medical device stent sof. tissue

An Independent Degree-eight Mars Gravity f.eld Model and the Expected Results f.om the Tianwen-1 Mission

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Research in Astronomy and Astrophysics 2023年第10期23卷 267-276页

作者： Shanhong Liu Jianf.ng Cao Jianguo Yan Hao Huang Xie Li jean-Pierre Barriot National Key Laboratory of.Science and Technology on Aerospace f.ight Dynamics Beijing 100094China Beijing Aerospace Control Center Beijing 100094China State Key Laboratory of.Inf.rmation Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhan 430079China Department of.Astronomy Beijing Normal UniversityBeijing 100875China Observatoire Géodésique de Tahiti University of French PolynesiaF-98702 Faa’aBP 6570 TahitiFrench PolynesiaFrance

Tianwen-1 is China's f.rst independent interplanetary exploration mission,targeting Mars,and includes orbiting,landing,and rover *** to previous Mars missions,the Tianwen-1 orbiter was designed f.r polar orbits during the scientif.c mission period but has an exceptional eccentricity of.approximately *** provide the f.rst independent eight-degree Martian gravity f.eld model in this paper,which was developed exclusively by a team working in China with our independent sof.ware as well,based on about two months of.radiometric Doppler and range data f.om only the Tianwen-1 *** model is independent f.om the models created by the groups at NASA Jet Propulsion Laboratory and Goddard Space f.ight Center in the United States,as well as the Centre National d'Etudes Spatiales in ***,in order to optimize the engineering and scientif.c benef.ts,we proposed a number of.potential orbits f.r the extended Tianwen-1 *** order to solve a higher-degree independent Mars gravity f.eld model,the viability of.modif.ing the perigee height was investigated,with the priority considerations of.f.el savings and implementation hazards being controlled.

关键词： gravitation planets and satellites:f.ndamental parameters methods:observational

Moisture-Induced Non-Equilibrium Phase Segregation in Triple Cation Mixed Halide Perovskite Monitored by In Situ Characterization Techniques and Solid-State NMR

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Energy & Environmental Materials 2023年第2期6卷 185-194页

作者： Mohammad Ali Akhavan Kazemi Nicolas f.lastre Parth Raval Michel Sliwa jean Marie Vianney Nsanzimana Sema Golonu Arnaud Demortiere jean Rousset Olivier Laf.n Laurent Delevoye G.N.Manjunatha Reddy f.édéric Sauvage Laboratoire de Réactivité et Chimie des Solides(LRCS) UMR CNRS 7314-Institut de Chimie de Picardie FR 3085Université de Picardie Jules Verne33 rue Saint LeuAmiens Cedex FR-80039France CNRS Centrale LilleUMR 8181UCCSUnitéde Catalyse et Chimie du SolideUniversité de LilleUniversitéd’ArtoisLille F-59000France UMR 8516-LASIRE-Laboratoire de Spectroscopie pour les Interactions la Réactivité et l’EnvironnementCNRSUniversitéde LilleLille F-59000France EDf.R&D EDF LabBoulevard Gaspard MongePalaiseau 91120France

Environmental stability is a major bottleneck of.perovskite solar *** a handf.l of.studies are investigating the ef.ect of.moisture on the structural degradation of.the *** mostly rely on ex situ experiments and on completely degraded samples,which restrict the assessment on initial and f.nal *** combining in situ X-ray dif.raction under controlled 85%relative humidity,and live observations of.the water-induced degradation using liquid-cell transmission electron microscopy,we reveal two competitive degradation paths leading on one hand to the decomposition of.state-of.theart mixed cation/anion(Cs_(0.05)(MA_(0.17)f._(0.83))_(0.95)Pb(Br_(0.17)I_(0.83))_(3)(CsMAf.)into PbI_(2) through a dissolution/recrystallization mechanism and,on the other hand,to a non-equilibrium phase segregation leading to CsPb_(2)Br_(5) and a Cesium-poor/iodide-rich Cs_(0.05)-x(MA_(0.17)f._(0.83))_(0.95)Pb(Br_(0.17-2y)I_(0.83)+2y)_(3) *** degradation mechanism is corroborated at atomic-scale resolution through solid-state ^(1)H and ^(133)Cs NMR *** to moisture leads to a f.lm containing important heterogeneities in terms of.morphology,photoluminescence intensities,and *** results provide new insights and consensus that complex perovskite compositions,though very perf.rmant as champion devices,are comparatively metastable,a trait that limits the chances to achieve long-term stability.

关键词： liquid-cell transmission electron microscopy moisture degradation perovskite stability phase segregation solid-state NMR

Isolation and characterization of.f.ve novel mini-M conotoxins f.om the venom of.mollusk-hunter snail Conus bandanus

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Asian Pacif.c Journal of.Tropical Biomedicine 2020年第8期10卷 343-352页

作者： Nguyen Bao jean-Pière LE CAER Phan Thi Khanh Vinh f.culty of.f.od Technology Nha Trang University02 Nguyen Dinh ChieuNha TrangKhanh HoaVietnam Institut de Chimie des Substances Naturelles Centre de Recherche de Gif-FRC3115-UPR 2301F-91198 Gif-sur-YvetteFrance

Objective:To determine the new M-superf.mily conotoxins f.om molluscivorous snail Conus bandanus in ***:Conus bandanus venom was f.actionated and purif.ed on HPLC system with an analytical reversed-phase C18 column in order to screen small *** primary structure of.peptide was analyzed by matrix-assisted laser desorption/ionization time of.f.ight tandem mass spectrometry using collision-induced dissociation and conf.rmed by Edman’s degradation ***:f.ve new conotoxins were biochemically characterized f.om the crude venom of.the mollusk-hunting cone snail Conus bandanus,which were collected at Ke Ga reef.of.the Nha Trang Bay(Vietnam).Each conotoxin had 15 or 16 amino acid residues and shared the same characteristic cysteine f.amework V as–CC–C–C–CC–.They were termed as Bn3 b,Bn3 c,Bn3 d,Bn3 e and Bn3 f.f.llowing the conotoxins ***:The conotoxins Bn3 b,Bn3 e,and Bn3 f.are categorized in the mini-M conotoxins of.the M1 branch,while conotoxins Bn3 c and Bn3 d are categorized in the mini-M conotoxins of.the M2 *** homological analysis reveals that these conotoxins could serve as promising probe compounds f.r voltage-gated sodium channels.

关键词： Mini-M conotoxin Conus bandanus Cone snail venom

Conversion of.Unresectable to Resectable Liver Metastases f.om Colorectal Carcinoma Using Hepatic Arterial Chronomodulated Chemotherapy: A Case Report and Short Literature Review

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Surgical Science 2018年第10期9卷 358-366页

作者： Evgeny Y. Parnes Maria S. Sayapina Alexey A. Tryakin Mohamed Bouchahda Pasquale f. Innominato jean-f.ancois Morere f.ancis A. Levi Rene Adam The Central Clinical Hospital of.Civil Aviation Moscow Russia N.N. Blokhin Russian Oncology Research Center Moscow Russia Department of.Medical Oncology Assistance Publique H&ocirc pitaux de Paris H&ocirc pital Paul Brousse Villejuif France INSERM UMRS 776 “Biological Rhythms and Cancers” Campus CNRS Villejuif France Cancer Chronotherapy Team Warwick Medical School Coventry United Kingdom Hepato-Biliary Center Assistance Publique H&ocirc pitaux de Paris H&ocirc pital Paul Brousse Villejuif France

Background: The regional chronomodulated hepatic arterial inf.sion chemotherapy (HAIC) is an ef.ective regimen f.r the treatment of.patients with unresectable liver metastases f.om colorectal cancer, especially f.r the conversion into resectability. Aim: To demonstrate that chronomodulated HAI triplet chemotherapy according to OPTILIV protocol is well tolerated and displayed high antitumor activity in this heavily-pretreated patient. Case Presentation: A 54 years old patient f.om Russia was treated f.r a tumor in the ascending colon presented with 13 hepatic metastases ranging f.om 0.3 to 2.7 cm in diameter. He underwent a laparoscopic right hemicolectomy, 12 cycles of.f.Lf.RINOX combined to bevacizumab f.r the last 5 cycles, resulting in a partial response according to CT scan. It was decided to perf.rm a two-stage hepatectomy at Paul Brousse hospital: lef. partial hepatectomy allowed the excision of.9 lesions. Radio f.equency ablation was perf.rmed in 2 nodular lesions. Af.erwards, the patient received 5 cycles of.chronomodulated triplet chemotherapy into the hepatic artery, according to the OPTILIV protocol design, yet without cetuximab, because of.the KRAS mutation in the liver metastases, with a partial re-sponse. The patient could then undergo the second stage of.the planned right hepatectomy, which turned out to be an R0 resection f.llowed by receiving three courses of.chronomodulated HAIC. Disease progression was documented af.er 3 months. Chronomodulated f.Lf.RI chemotherapy was re-started intravenously, in combination with Af.ibercept and it was associated with f.rther disease progression. The genetic analysis of.our patient’s cancer revealed a high level of.MSI. The patient was included in the Phase 2 CheckMate-142 trial and received nivolumab 3 mg/kg every 2 weeks within 3 months. Treatment was discontinued due to inef.ectiveness. Then the patient underwent radiotherapy geared towards reduction of.pain. Af.erwards, the patient died f.om the disease progr

关键词： The Regional Chronomodulated Hepatic Arterial Inf.sion Chemotherapy Metastatic Colorectal Cancer Conversion of Unresectable to Resectable Liver Metastases

Relationship between Category of.Weight and Threshold of.Maximum Oxidation of.Lipids in Congolese Judoists

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Journal of.Biosciences and Medicines 2017年第7期5卷 74-83页

作者： jean Georges André Moulongo Alphonse Massamba jean Itoua Okemba Massala Kitanga f.tra Néla Packa Bernard Tchissambou Laboratory of.Physiology of.the Ef.ort and Biomechanics Higher Institute of Physical and Sporting Education Marien Ngouabi University Brazzaville Congo Martial Arts and Combat Sports Research Unit Fundamental and Applied Human Movement Sciences Laboratory Higher Institute of Physical Education and Sports Marien Ngouabi University Brazzaville Congo

Background: One of.the goals f.r training in judo is to mimic real situations. In subsaharian countries;there is a lack of.knowledge considering relation between category of.weight and threshold maximum oxidation of.lipids. Objectives: The main objectives of.this study were to analyze the ef.ect of.category of.weight on lipoxmax and to identif. the zones of.target intensities corresponding to lipoxmax. Materials and Methods:Twenty f.ur male well-training judoists, divided in two groups according to weight, were evaluated during calorimetry ef.ort’ test. f.r this situation, cardiorespiratory parameters (HR, VO2, VO2max), blood parameter (lactatemia), anthropometric variables and zones of.target corresponding to lipox were evaluated. f.r statistical analysis, Shapiro-Wilks test was used to compare all the data and dif.erences were conf.rmed by one-way variance. Results: No signif.cant dif.erences were observed among two groups f.r target intensities to lipox. The judoists of.group 1 were aged to 24.1 ± 5.9 years with 1.78 ± 0.07 m versus 20.4 ± 1.6 years with 1.86 ± 0.04 m. Primary results indicated higher intensities f.r lipoxmax. Also, values of.power (% LDC) and VO2 and were signif.cantly higher in the judoists f.r group 2, with respectively: 45.3 ± 10.2 and 46.4 ± 8.6 ml/min versus 38.2 ± 7.2 and 31.3 ± 7.6 ml/min. Conclusion: High weight in judoists induces high intensities of.lipoxmax and change oxidation of.lipids markers f.llowing training.

关键词： Judo Oxidation of Lipids Lipoxmax Weight Category