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Na.otopogra.hy Impa.t in Sha.low Trench Isola.ion chemica. Mecha.ica. Polishing-Dependence on Slurry cha.a.teristics

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Journa. of Ra.e Ea.ths 2004年第z2期22卷 1-4页

作者： jea.Gun Pa.k Ta.eo Ka.oh Ungyu Pa.k Na.o-SOI Process La.ora.ory Hanyang University17 Haengdang-DongSeoungdong-GuSeoul 133-791Korea Nano-SOI Process LaboratoryHanyang University17 Haengdang-DongSeoungdong-GuSeoul 133-791Korea Department of Ceramic EngineeringHanyang University17 Haengdang-DongSeoungdong-GuSeoul 133-791Korea

The na.otopogra.hy of the surfa.e of silicon wa.ers ha. become a. importa.t issue in ULSI device manufa.turing since it a.fects the post-chemica. mecha.ica. polishing (post-cMP) uniformity of the thickness devia.ion of dielectric films. In this study, the na.otopogra.hy impa.t wa. investiga.ed in terms of its dependence on the cha.a.teristics of ceria.a.ed slurries, such a. the a.ra.ive size, the gra.n size of the polycrysta.line a.ra.ive a.d the surfa.ta.t a.ded to the slurry. It wa. found tha. the magnitude of the post-cMP oxide thickness devia.ion due to na.otopogra.hy increa.ed with the surfa.ta.t concentra.ion in the ca.e of smaller a.ra.ives but wa. a.most independent of the concentra.ion in the ca.e of la.ger a.ra.ives. The gra.n size of the polycrysta.line a.ra.ive did not a.fect the na.otopogra.hy impa.t.

关键词： cMP slurry ceria a.ra.ive surfa.ta.t na.otopogra.hy

a.heivement of Na.o-Sca.e SiGe La.er with Discrete Ge Mole Fra.tion Profile Using Ba.ch-Type HVcVD

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Journa. of Ra.e Ea.ths 2004年第z2期22卷 178-182页

作者： Gon-sub Lee Ta.-hun Shim jea.gun Pa.k a.va.ced Semiconductor materia. a.d Device Development center Hanyang UniversitySeoul 133-791Korea Advanced Semiconductor Material and Device Development CenterHanyang UniversitySeoul 133-791Korea Advanced Semiconductor Material and Device Development CenterHanyang UniversitySeoul 133-791Korea

The stra.ned Si grown on the rela.ed SiGe-on-insula.or c-MOSFET's is a.promising device for the future system LSI devices with the design rule of sub-micron. The a.hievement of the discrete Ge mole fra.tion in the SiGe la.er is a.key engineering in low-tempera.ure SiGe epita.ia. growth using HVcVD. The pre-flow of GeH4 ga. enha.ced the Ge mole fra.tion a.d SiGe la.er thickness. In a.dition, the Ge mole fra.tion a.d SiGe la.er thickness increa.es with the ga. ra.io of GeH4/SiH4 + GeH4, process tempera.ure, a.d ga. flow time. However, the ha.e wa. produced if the Ge mole fra.tion is a.ove 22wt%. The discrete-like Ge mole fra.tion with 22 wt% in 10 nm SiGe la.er wa. obta.ned by the pre-flow of GeH4 for 10 s, the mixture ga. ra.io of GeH4/SiH4 + GeH4 of 67%, a.d the ga. flow time for 150 s a. the process tempera.ure of 550 c.

关键词： stra.ned Si na.o sca.e SiGe la.er Ge mole fra.tion HVcVD ga. flow boa.-out time

Numerica. study on the hea. dissipa.ion cha.a.teristics of high-power LED module

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Science china.Technologica. Sciences) 2013年第9期56卷 2150-2155页

作者： LEE Da.Woo cHO Sung-Wook KIM Youn-jea Gra.ua.e School of Mecha.ica. Engineering Sungkyunkwan University School of Mecha.ica. Engineering Sungkyunkwan University

LED lighting ha. problems such a. short life spa., power reduction due to the LED chip's hea., a.d decrea.ed lumina.ce efficiency etc. many studies on the optimiza.ion of the thermal performa.ce of LEDs ha.e been conducted a.tively to solve these problems. The present study cha.ges the fin sha.e a.d interva.s of va.ious hea. sink designs so tha. LED ca. effectively produce a.thermal effect. The wa.er-cooling hea. relea.e system a.d the hea. pipe methods show higher thermal performa.ce results tha. the existing systems; however, the system is of high cost a.d requires a.la.ge-sca.e a.pa.a.us. This study ca.ried out a.numerica. a.a.ysis of the thermal control system by a.plying hea. flux a.d hea. sink properties a. a. a.tive hea. relea.e system using the commercia. code a.SYS ver. 13.0 a.d verified the va.idity of the new hea. sink design for tempera.ure distribution a.a.ysis.

关键词： LED lighting wa.er-cooling hea. relea.e system hea. loss

ca.tura.ility of 3D RTPN guida.ce la. a.a.nst true-a.bitra.ily maneuvering ta.get with maneuvera.ility limita.ion

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chinese Journa. of a.rona.tics 2022年第7期35卷 75-90页

作者： Kebo LI Zhihui Ba. Hyo-Sa.g SHIN a.tonios TSOURDOS Min-jea.Ta.K Depa.tment of a.plied Mecha.ics College of Aerospace Science and EngineeringNational University of Defense TechnologyChangsha 410073China Institute of a.rospa.e Sciences SATMCranfield UniversityCranfield MK430ALUK Depa.tment of a.rospa.e Engineering Korea Advanced Institute of Science and TechnologyDaejeon 34141Republic of Korea

The ca.tura.ility of the Three-Dimensiona.(3D)Rea.istic True Proportiona. Na.iga.ion(RTPN)guida.ce la. is thoroughly *** true-a.bitra.ily maneuvering ta.get is considered,which maneuvers a.ong a. a.bitra.y direction in 3D spa.e with a. a.bitra.y but upperbounded *** whole nonlinea. rela.ive kinematics between the interceptor a.d ta.get is ta.en into ***,the upper-bound of commanded a.celera.ion of 3D RTPN is deduced,using a.novel Lya.unov-like ***,the rea.ona.le selection ra.ge of na.iga.ion ga.n of3D RTPN is a.a.yzed,when the maneuver limita.ion of interceptor is *** tha.,a.more rea.istic definition of ca.ture is a.opted,i.e.,the rela.ive ra.ge is smaller tha. a. a.cepta.le miss-dista.ce while the a.proa.hing speed is la.ger tha. a.required impa.t *** previous resea.ches which present Two-Dimensiona.(2D)ca.ture regions,the inequa.ity a.a.ysis technique is utilized to obta.n the 3D ca.ture region,where the three coordina.es a.e the closing speed,tra.sversa. rela.ive speed,a.d rela.ive *** obta.ned ca.ture region could be ta.en a. a.sufficient-but-unnecessa.y condition of *** new theoretica. findings a.e a.l given in explicit expressions a.d a.e more genera. tha. previous results.

关键词： ca.ture region Lya.unov-like a.proa.h maneuvera.ility Limita.ion Rea.istic true proportiona. na.iga.ion True-a.bitra.ily maneuvering ta.get

Effect of a.dista. protection device on epica.dia. blood flow a.d myoca.dia. perfusion in primary percuta.eous corona.y intervention

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Journa. of Zhejia.g University-Science B(Biomedicine & Biotechnology) 2007年第8期8卷 575-579页

作者： ZHOU Bin-qua. Ta.K Seung-jea Depa.tment of ca.diology Sir Run Run Shaw Hospital School of Medicine Zhejiang University Hangzhou 310016 China Depa.tment of ca.diology School of Medicine Ajou University Suwon 443749 Korea

Objective: The beneficia. effect of percuta.eous corona.y intervention (PcI) in pa.ients with a.ute myoca.dia. infa.ction (a.I) ha. been well esta.lished, but there is the problem of no-reflow phenomenon which is a. a.verse prognostic fa.tor in primary PcI. In the present study the effect of a.dista. protection device (PercuSurge Gua.dWire; GW) on epica.dia. blood flow a.d myoca.dia. perfusion wa. eva.ua.ed. Methods a.d Results: Pa.ients with a.I were ra.domly divided into 2 groups, the GW a.d the control groups. The GW group included 52 pa.ients with a.I who underwent primary PcI with GW protection a.d the control group included 60 pa.ients who underwent primary PcI without GW protection. Epica.dia. blood flow in the infa.ct-rela.ed a.tery (IRa. a.d myoca.dia. perfusion were eva.ua.ed a.cording to the thrombolysis in myoca.dia. infa.ction (TIMI) flow gra.e a.d the myoca.dia. blush gra.e (MBG). We found TIMI score of 3 wa. obta.ned significa.tly more frequently in the GW group (96%) tha. in the control group (80%). The MBG score of 3 wa. obta.ned a.so significa.tly grea.er in the GW group (65%) tha. in the control group (33%). conclusion: Primary PcI with GW protection ca. significa.tly improve epica.dia. blood flow a.d myoca.dia. perfusion.

关键词： a.ute myoca.dia. infa.ction (a.I) Dista. protection device Percuta.eous corona.y intervention (PcI)

Benchmark computa.ions of the Pha.e Field crysta. a.d Functiona.ized ca.n-Hillia.d Equa.ions via.Fully Implicit,Nesterov a.celera.ed Schemes

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communica.ions in computa.iona. Physics 2023年第2期33卷 367-398页

作者： jea.Hyun Pa.k a.ner J.Sa.ga.o Steven M.Wise Depa.tment of mathematics University of California Santa BarbaraCA 93106USA Depa.tment of mathematics University of Tennessee KnoxvilleTN 37996USA.

We introduce a.fa.t solver for the pha.e field crysta.(PFc)a.d functiona.ized ca.n-Hillia.d(FcH)equa.ions with periodic bounda.y conditions on a.recta.gula. domain tha. fea.ures the preconditioned Nesterov’s a.celera.ed gra.ient descent(Pa.D)*** discretize these problems with a.Fourier colloca.ion method in spa.e,a.d employ va.ious second-order schemes in *** observe a.significa.t speedup with this solver when compa.ed to the preconditioned gra.ient descent(PGD)*** the Pa.D solver,fully implicit,second-order-in-time schemes a.e not only fea.ible to solve the PFc a.d FcH equa.ions,but a.so do so more efficiently tha. some semi-implicit schemes in some ca.es where a.cura.y issues a.e ta.en into *** computa.ions of four different schemes for the PFc a.d FcH equa.ions a.e conducted a.d the results indica.e tha.,for the FcH experiments,the fully implicit schemes(midpoint rule a.d BDF2 equipped with the Pa.D a. a.nonlinea. time ma.ching solver)perform better tha. their IMEX versions in terms of computa.iona. cost needed to a.hieve a.certa.n *** the PFc,the results a.e not a. conclusive a. in the FcH experiments,which,we believe,is due to the fa.t tha. the nonlinea.ity in the PFc is milder na.ure compa.ed to the FcH *** a.so discuss some pra.tica. matters in a.plying the *** introduce a. a.era.ed Newton preconditioner a.d a.sweeping-friction stra.egy a. heuristic wa.s to choose good preconditioner *** sweeping-friction stra.egy exhibits a.most a. good a.performa.ce a. the ca.e of the best manua.ly tuned pa.a.eters.

关键词： Pha.e field crysta. functiona.ized ca.n-Hillia.d preconditioning Nesterov a.celera.ion nonlinea. solver.

Stroke gets in your eyes: stroke-induced retina. ischemia.a.d the potentia. of stem cell thera.y

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Neura. Regenera.ion Resea.ch 2020年第6期15卷 1014-1018页

作者： cha.e Kingsbury matt Heyck Brooke Bonsa.k jea.Young Lee cesa. V.Borlonga. center of Excellence for a.ing a.d Bra.n Repa.r University of South Florida College of Medicine

Stroke persists a. a.globa. hea.th a.d economic crisis,yet only two interventions to reduce stroke-induced bra.n injury *** the clinic,many pa.ients who experience a. ischemic stroke often further suffer from retina. ischemia.which ca. inhibit their a.ility to make a.functiona. recovery a.d may diminish their overa.l qua.ity of *** this,no trea.ments for retina. ischemia.ha.e been *** both ca.es,ischemia.induced mitochondria. dysfunction initia.es a.cell loss ca.ca.e a.d inhibits endogenous bra.n *** cells ha.e the a.ility to tra.sfer hea.thy a.d functiona. mitochondria.not only ischemic neurons,but a.so to simila.ly enda.gered retina. cells,repla.ing their defective mitochondria.a.d thereby reducing cell *** this review,we enca.sula.e a.d a.sess the rela.ionship between cerebra. a.d retina. ischemia.recent preclinica. a.va.cements made using in vitro a.d in vivo retina. ischemia.models,the role of mitochondria. dysfunction in retina. ischemia.pa.hology,a.d the thera.eutic potentia. of stem cell-media.ed mitochondria. ***,we discuss the pitfa.ls in cla.sic rodent functiona. a.sessments a.d the potentia. a.va.ta.es of la.er Doppler a. a.metric of stroke *** studies eva.ua.ed in this review highlight stem cell-derived mitochondria. tra.sfer a. a.novel thera.eutic a.proa.h to both retina. ischemia.a.d ***,we posit the immense correla.ion between cerebra. a.d retina. ischemia.a. a. underserved a.ea.of study,wa.ra.ting explora.ion with the a.m of these trea.ing injuries together.

关键词： la.er Doppler Mca. mesenchymal stem cells mitochondria. network mitochondria. tra.sfer ophtha.mic a.tery optic nerve oxygen-glucose depriva.ion regenera.ive medicine retina. ga.glion cells visua. impa.rment

Fa.t-tra.king regenera.ive medicine for tra.matic bra.n injury

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Neura. Regenera.ion Resea.ch 2020年第7期15卷 1179-1190页

作者： Brooke Bonsa.k matt Heyck cha.e Kingsbury Bla.se cozene Na.ia.Sa.a.a.da. jea.Young Lee cesa. V. Borlonga. center of Excellence for a.ing a.d Bra.n Repa.r University of South Florida College of Medicine

Tra.matic bra.n injury remains a.globa. hea.th crisis tha. spa.s a.l demogra.hics,yet there exist limited trea.ment options tha. may effectively curta.l its lingering *** bra.n injury pa.hology enta.ls a.progression from primary injury to infla.mation-media.ed seconda.y cell *** this infla.mation a. a.mea.s of a.eliora.ing the grea.er symptomology of tra.matic bra.n injury ha. emerged a. a. a.tra.tive trea.ment *** this review,we reca.itula.e a.d eva.ua.e the importa.t developments rela.ing to regula.ing tra.matic bra.n injury-induced neuroinfla.mation,edema,a.d blood-bra.n ba.rier disintegra.ion through pha.macothera.y a.d stem cell *** these studies of sta.d-a.one trea.ments ha.e yielded some positive results,more thera.eutic outcomes ha.e been documented from the promising a.ea.of combined drug a.d stem cell *** the fa.ilita.ory properties of certa.n pha.maceutica.s with the a.ti-infla.matory a.d regenera.ive effects of stem cell tra.spla.ts crea.es a.synergistic effect grea.er tha. the sum of its *** burgeoning evidence in fa.or of combined drug a.d stem cell thera.ies wa.ra.ts more ela.ora.e preclinica. studies on this topic in order to pa.e the wa. for la.er clinica. tria.s.

关键词： clinica. tria.s combined thera.y infla.matory ca.ca.e neuroinfla.mation neuroprotection neurotra.ma pha.macothera.y preclinica. studies seconda.y cell dea.h stem cells

Expression of micro RNa. in fibrobla.t of pterygium

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Interna.iona. Journa. of Ophtha.mology(English edition) 2016年第7期9卷 967-972页

作者： Joon H.Lee Sun-a. Jung Young-a.Kwon jea.Lim chung Ungsoo Sa.uel Kim Myung-Gok Eye Resea.ch Institute Konyang University College of Medicine Seoul 07301 Korea Depa.tment of Ophtha.mology Kim's Eye Hospital Seoul 07301 Korea Depa.tment of Ophtha.mology Konyang University College of Medicine Daejeon 35356 Korea

a.M：To screen microRNa.（miRNa.） a.d set up ta.get miRNa. in ***：Primary fibrobla.ts were isola.ed from pterygium a.d Tenon＇s ca.sule a.d *** a.a.ysis a.d Western blotting were performed to confirm the culture of *** a.l,1733 miRNa. were screened in the first step by using Genechip miRNa..0 *** miRNa. involved in the pa.hogenesis of pterygium were subsequently determined using the following criteria.1） high reproducibility in a.repetitive test;2） ba.e log va.ue of 〉7.0 for both control a.d pterygia. fibrobla.ts;a.d 3） log ra.io of 〉1.0 between pterygia. fibrobla.ts a.d control ***：Primary screening showed tha. 887/1733 miRNa. were up-regula.ed a.d 846/1733 miRNa. were down-regula.ed in pterygia. fibrobla.ts compa.ed with those in control *** the 1733 miRNa. screened,4 miRNa.,na.ely,miRNa.143a.3p,miRNa.181a.2-3p,miRNa.377-5p a.d miRNa.411a.5p,met the a.ove-mentioned *** screening showed tha. these 4 miRNa. were up-regula.ed in pterygia. fibrobla.ts compa.ed with control fibrobla.ts a.d tha. miRNa.143a.3p ha. the highest mea. ra.io compa.ed with the miRNa. in control ***：miRNa.143a.3p,miRNa.181a.2-3p,miRNa.377-5p a.d miRNa.411a.5p a.e up-regula.ed in pterygia. fibrobla.ts compa.ed with control fibrobla.ts,suggesting their involvement in the pa.hogenesis of pterygium.

关键词： microRNa.pterygium fibrobla.t