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Temperature Responses to Infrared-Loading and Water Table Manipulations in Peatland Mesocosms

Journal of Integrative Plant Biology 2008年第11期50卷 1484-1496页

作者： Jiquan Chen Scott Bridgham jason keller John Pastor Asko Noormets Jake F.Weltzin Department of Environmental Sciences University of Toledo Center for Ecology and Evolutionary Biology University of Oregon Smithsonian Environmental Research Center Department of Biological Sciences University of Minnesota National Phenology Network

We initiated a multi-factor global change experiment to explore the effects of infrared heat loading （HT） and water table level （WL） treatment on soil temperature （T） in bog and fen peatland mesocosms. We found that the temperature varied highly by year, month, peatland type, soil depth, HT and WL manipulations. The highest effect of HT on the temperature at 25 cm depth was found in June for the bog mesocosms （3.34-4.27 ℃） but in May for the fen mesocosms （2.32-4.33 ℃） over the 2-year study period. The effects of WL in the bog mesocosms were only found between August and January, with the wet mesocosms warmer than the dry mesocosms by 0.48-2.03 ℃ over the 2-year study period. In contrast, wetter fen mesocosms were generally cooler by 0.16-3.87℃. Seasonal changes of temperatures elevated by the HT also varied by depth and ecosystem type, with temperature differences at 5 cm and 10 cm depth showing smaller seasonal fluctuations than those at 25 cm and 40 cm in the bog mesocosms. However, increased HT did not always lead to warmer soil, especially in the fen mesocosms. Both HT and WL manipulations have also changed the length of the non-frozen season.

关键词： global change infrared mesocosm peatlands warming experiment water table.

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吸入麻醉药增加β淀粉样蛋白的寡聚化反应和细胞毒性

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国外医学（麻醉学与复苏分册） 2004年第5期25卷 320-320,i001,i002页

作者： Roderic G.Eckenhoff M.D. Jonas S.Johansson M.D. Ph.D. Huafeng Wei M.D. Ph.D. Anna Carnini Ph.D. Baobin Kang M.D. Wenlin Wei M.D. Ravindernath Pidikiti M.D. jason M.keller B.Sc. Maryellen F.Eckenhoff Ph.D. 王耀岐 Professor Departments of Anesthesia and Physiology Associate Professor Departments of Anesthesia and Biochemis- try/Biophysics and the Johnson Foundation University of Pennsylvania Philadelphia Pennsylvania. Assistant Professor Researeh Scien- tist Department of Anesthesia Assistant Professor Research Fellow Department of Anesthesia Assistant Professor Research Specialist Department of Anesthesia Assistant Professor Research Technician Depament of Anesthesia Assistant Professor Research Associate Department of Anesthesia Assistant Professor Research Scientist Department of Anesthesia 徐州医学院江苏省麻醉举重点实验室

背景:多数外科病人都接受过吸入麻醉药,主要是小分子卤代烃和卤代醚类.长期任知功能障碍发生于麻醉和手术后的老年病人.对神经变性疾病如阿尔茨海默病和帕金森病病人来说,以前接受过手术可能也一个是危险诱发因素.作者认为吸入麻醉药可... 详细信息

背景:多数外科病人都接受过吸入麻醉药,主要是小分子卤代烃和卤代醚类.长期任知功能障碍发生于麻醉和手术后的老年病人.对神经变性疾病如阿尔茨海默病和帕金森病病人来说,以前接受过手术可能也一个是危险诱发因素.作者认为吸入麻醉药可能通过增强肽的持久寡聚化诱发上述疾病.

关键词：吸入麻醉药 β淀粉样蛋白细胞毒性外科病人功能障碍神经变性疾病老年病人作者卤代烃反应

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Are EPB41 and alpha-synuclein diagnostic biomarkers of sport-related concussion?Findings from the NCAA and Department of Defense CARE Consortium

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Journal of Sport and Health Science 2023年第3期12卷 379-387页

作者： Rany Vorn Christina Devoto Timothy B.Meier Chen Lai Sijung Yun Steven P.Broglio Sara Mithani Thomas W.McAllister Christopher C.Giza Hyung-Suk Kim Daniel Huber Jaroslaw Harezlak Kenneth L.Cameron Gerald McGinty Jonathan Jackson Kevin M.Guskiewicz jason P.Mihalik Alison Brooks Stefan Duma Steven Rowson Lindsay D.Nelson Paul Pasquina Michael A.McCrea Jessica M.Gill the CARE Consortium Investigators Johns Hopkins School of Nursing and Medicine BaltimoreMD 21205USA National Institutes of Health BethesdaMD 20892USA Department of Neurosurgery Medical College of WisconsinMilwaukeeWI 53226USA Predictiv Care Inc.Mountain ViewCA 94086USA Michigan Concussion Center University of MichiganAnn ArborMI 48109USA Department of Psychiatry Indiana University School of MedicineIndianapolisIN 46202USA Departments of Pediatrics and Neurosurgery University of California at Los Angeles(UCLA)Los AngelesCA 90024USA Department of Epidemiology and Biostatistics School of Public Health–Bloomington Indiana UniversityBloomingtonIN 47405USA John A.Feagin Sports Medicine Fellowship Keller Army Community HospitalWest PointNY 10996USA United States Air Force Academy Colorado SpringsCO 80840USA Mathew Gfeller Center Department of Exercise and Sport ScienceUniversity of North Carolina at Chapel HillChapel HillNC 27514USA Department of Orthopedics Division of Sports MedicineSchool of Medicine and Public HealthUniversity of WisconsinMadisonWI 53705USA Department of Biomedical Engineering and Mechanics Virginia TechBlacksburgVA 24061USA Center for Neuroscience&Regenerative Medicine Uniformed Services UniversityBethesdaMD 20814USA 不详 Current affiliation:School of Nursing University of Texas Health Science Center San AntonioSan AntonioTX 78229USA

Background:Current protein biomarkers are only moderately predictive at identifying individuals with mild traumatic brain injury or ***,more accurate diagnostic markers are needed for sport-related ***:This was a multicenter,prospective,case-control study of athletes who provided blood samples and were diagnosed with a concussion or were a matched non-concussed control within the National Collegiate Athletic Association-Department of Defense Concussion Assessment,Research,and Education Consortium conducted between 2015 and *** blood was collected within 48 h of injury to identify protein abnormalities at the acute and subacute *** with concussion were divided into 6 h post-injury(0-6 h post-injury)and after 6 h postinjury(7-48 h post-injury)*** applied a highly multiplexed proteomic technique that used a DNA aptamers assay to target 1305proteins in plasma samples from athletes with and without sport-related ***:A total of 140 athletes with concussion(79.3%males;aged 18.71±1.10 years,mean±SD)and 21 non-concussed athletes(76.2%males;19.14±1.10 years)were included in this *** identified 338 plasma proteins that significantly differed in abundance(319 upregulated and 19 downregulated)in concussed athletes compared to non-concussed *** top 20 most differentially abundant proteins discriminated concussed athletes from non-concussed athletes with an area under the curve(AUC)of 0.954(95%confidence interval:0.922-0.986).Specifically,after 6 h of injury,the individual AUC of plasma erythrocyte membrane protein band 4.1(EPB41)and alpha-synuclein(SNCA)were 0.956 and 0.875,*** combination of EPB41 and SNCA provided the best AUC(1.000),which suggests this combination of candidate plasma biomarkers is the best for diagnosing concussion in athletes after 6 h of ***:Our data suggest that proteomic profiling may provide novel diagnostic protein markers and that a combina

关键词： Biomarkers College athletes Concussion Mild traumatic brain injury Sport injury

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