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Hemophagocytic lymphohistiocytosis triggered by relapsing polychondritis:A case report

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World Journal of Orthopedics 2024年第8期15卷 813-819页

作者： Mi-Ran Han Jeong-Hwan Hwang Seungah Cha So-Yeon Jeon Kyu Yun jang Namsu Kim Chang-Hoon Lee Department of Internal Medicine Jeonbuk National University Medical SchoolJeonju 54907South Korea Department of Pathology Jeonbuk National University Medical SchoolJeonju 54907South Korea Department of Laboratory Medicine Jeonbuk National University Medical SchoolJeonju 54907South Korea

BACKGROUND Hemophagocytic lymphohistiocytosis(HLH)is a rare,life-threatening disorder caused by abnormal histiocytes and T cell *** adults,it is predominantly associated with infections,cancers,and autoimmune *** polychondritis(RP),another rare disease,is diagnosed based on symptoms without specific tests,featuring cartilage inflammation characterized by swelling,redness,and pain,rarely inducing *** SUMMARY A 74-year-old woman visited the emergency room with a fever of 38.6℃.Blood tests,cultures,and imaging were performed to evaluate *** showed increased fluorescent antinuclear antibody levels and mild cytopenia,with no other specific *** revealed lymph node enlargement was observed;however,biopsy results were *** re-evaluation of the physical exam,inflammatory signs suggestive of RP were observed in the ears and nose,prompting a tissue biopsy for ***,persistent fever accompanied by cytopenia prompted a bone marrow examination,revealing hemophagocytic *** finding no significant results in blood culture,viral markers,and tissue examination of enlarged lymph nodes,HLH was diagnosed by *** involved methylprednisolone followed by *** two months,bone marrow examination confirmed resolution of hemophagocytosis,with normalization of hyperferritinemia and *** Thorough physical examination enabled diagnosis and treatment of HLH trig gered by RP in patients presenting with fever of unknown origin.

关键词： Hemophagocytic lymphohistiocytosis Relapsing polychondritis Autoimmune disease Fever of unknown origin Steroid Case report

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页岩气地质工程一体化产能优化研究

地质论评 2024年第S1期70卷 339-341页

作者：蒋克成周刚刘胜昆仑数智科技有限责任公司智慧油田事业部北京100040

页岩气井的产能是地质、油藏、工程等方面众多参数的综合反映。页岩气开发过程中,产能的准确预测和优化对降本增效具有重大意义。然而,产能影响涉及方面广、因素多,常规方法进行的单因素分析拟合度较差,各影响因素相互关系难以确定。有... 详细信息

页岩气井的产能是地质、油藏、工程等方面众多参数的综合反映。页岩气开发过程中,产能的准确预测和优化对降本增效具有重大意义。然而,产能影响涉及方面广、因素多,常规方法进行的单因素分析拟合度较差,各影响因素相互关系难以确定。有些研究人员采用多属性进行非线性拟合的方法也很难尽如人意,而且这类方法一般都只是对已经施工的井进行产量预测,无法开展产能评价.

关键词：页岩气地质工程一体化产能优化机器学习

新时代中学英语教学融入德育的创新实践与思考

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基础外语教育 2024年第2期26卷 3-9,106页

作者：蒋炎富北京市第十二中学

育人的根本在于立德,学科育人则是落实立德树人根本任务的切入口和实现方式。中学英语教学融入德育过程中,面临着对“真善美”的认知不足以及对人工智能的冲击难以调适等诸多问题和挑战。在新的时代背景下,本文从构建教育大场域、重塑... 详细信息

育人的根本在于立德,学科育人则是落实立德树人根本任务的切入口和实现方式。中学英语教学融入德育过程中,面临着对“真善美”的认知不足以及对人工智能的冲击难以调适等诸多问题和挑战。在新的时代背景下,本文从构建教育大场域、重塑“真善美”、开发大场景、创设真课堂等方面提出发展策略,来有效开展德育建设,促进学生全面发展与成长。

关键词：英语教学德育学科育人

基于红外的TPA和IAOA BiLSTM电路芯片故障诊断

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激光与红外 2024年第4期54卷 574-583页

作者：王力朱猛马江燕中国民航大学电子信息与自动化学院机载电子系统深度维修实验室天津300300

为了提高电路芯片故障诊断准确率,超参数设置的效率以及特征提取效率,提出一种基于时间模式注意力机制(TPA)的改进算数优化算法(IAOA)优化双向长短期记忆网络(BiLSTM)的电路故障诊断方法。首先,利用IAOA搜寻BiLSTM的最优超参数组合,提... 详细信息

为了提高电路芯片故障诊断准确率,超参数设置的效率以及特征提取效率,提出一种基于时间模式注意力机制(TPA)的改进算数优化算法(IAOA)优化双向长短期记忆网络(BiLSTM)的电路故障诊断方法。首先,利用IAOA搜寻BiLSTM的最优超参数组合,提高模型诊断精度;然后使用TPA提取重要特征并分配权重,改善模型特征提取能力;最后,将红外摄像仪采集的红外温度数据输入到最优诊断模型中,实现电路芯片故障诊断。实验采用0~30 V可调稳压电源电路进行验证。结果表明,该模型对电路芯片故障诊断准确率高达9827,可实现对电路芯片的高准确率故障诊断。

关键词：红外技术芯片故障诊断双向长短期记忆网络算数优化算法时间模式注意力机制

Landscape of global urban environmental resistome and its association with local socioeconomic and medical status

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Science China(Life Sciences) 2024年第6期67卷 1292-1301页

作者： Jun Wu Yige Hu Michael H Perlin David Danko Jun Lu Manuela Oliveira Johannes Werner Maria M Zambrano Maria A Sierra Olayinka O Osuolale Paweł Łabaj Nicolás Rascovan Nur Hazlin Hazrin-Chong Soojin jang Haruo Suzuki Marina Nieto-Caballero Bharath Prithiviraj Patrick K H Lee Agnieszka Chmielarczyk Anna Różańska Yongxiang Zhao Lan Wang Christopher E Mason Tieliu shi Center for Bioinformatics and Computational Biology and the Institute of Biomedical SciencesSchool of Life SciencesEast China Normal UniversityShanghai 200241China Department of Biology Program on Disease EvolutionUniversity of LouisvilleLouisville 40292USA Weill Cornell Medicine New York 10065USA The Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine New York 10065USA Department of Pulmonary Medicine Shanghai Chest HospitalShanghai Jiao Tong UniversityShanghai 200025China i3S-Instituto de Investiga玢o e Inova玢o em Saúde Universidade do PortoPorto 4050-290Portugal Ipatimup-Instituto de Patologia e Imunologia Molecular da Universidade do Porto Porto 4200-465Portugal Departamento de Biologia Faculdade de CiênciasUniversidade do PortoPorto 4050-290Portugal High Performance and Cloud Computing Group Zentrum für Datenverarbeitung(ZDV)Eberhard Karls University of TübingenW鋍hterstra遝7672074TübingenGermany Corporación Corpogen Research Center Bogotá110311Colombia Applied Environmental Metagenomics and Infectious Diseases Research(AEMIDR) Department of Biological SciencesElizade UniversityIlara-Mokin 340271Nigeria Maopolska Centre of Biotechnology Jagiellonian UniversityKraków 30-005Poland Aix-Marseille Université Mediterranean Institute of OceanologyUniversitéde ToulonCNRSIRDUM 110Marseille 83041France Department of Biological Sciences and Biotechnology Faculty of Science and TechnologyUniversiti Kebangsaan Malaysia43600 UKM BangiSelangor Institut Pasteur Korea Seoul 13488Republic of Korea Faculty of Environment and Information Studies Keio UniversityFujisawaKanagawa 252-0882Japan University of Colorado at Boulder CivilEnvironmental and Architectural DepartmentBoulder 80303USA Brooklyn College of the City University of New York Brooklyn 11210USA School of Energy and Environment City University of Hong KongHong Kong 999077China Department of Microbiology Faculty of MedicineJagiellonian UniversityKraków 30-005Poland Biological Targeting Diagnosis and The

Antimicrobial resistance(AMR)poses a critical threat to global health and development,with environmental factors—particularly in urban areas—contributing significantly to the spread of antibiotic resistance genes(ARGs).However,most research to date has been conducted at a local level,leaving significant gaps in our understanding of the global status of antibiotic resistance in urban *** address this issue,we thoroughly analyzed a total of 86,213 ARGs detected within 4,728 metagenome samples,which were collected by the Meta SUB International Consortium involving diverse urban environments in 60 cities of 27 countries,utilizing a deep-learning based *** findings demonstrated the strong geographical specificity of urban environmental resistome,and their correlation with various local socioeconomic and medical *** also identified distinctive evolutionary patterns of ARG-related biosynthetic gene clusters(BGCs)across different countries,and discovered that the urban environment represents a rich source of novel *** study provides a comprehensive overview of the global urban environmental resistome,and fills a significant gap in our knowledge of large-scale urban antibiotic resistome analysis.

关键词： urban environment metagenome antibiotic resistance resistance diversity biosynthetic gene clusters

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单元视域下基于任务驱动模式的电流教学

物理通报 2024年第5期 61-65页

作者：蒋炜波清华大学附属中学北京100084

电流是初中物理电学推理论证运算的基础,电流的定义、测量,以及串并联电路的电流规律等一直是教与学的重难点,电流单位、电流表原理等则一直是教与学的盲点.在单元教学统领下基于任务驱动模式设计了系列任务,重组了电流教学的内容与实施... 详细信息

电流是初中物理电学推理论证运算的基础,电流的定义、测量,以及串并联电路的电流规律等一直是教与学的重难点,电流单位、电流表原理等则一直是教与学的盲点.在单元教学统领下基于任务驱动模式设计了系列任务,重组了电流教学的内容与实施,探索解决现实教学困境,落实核心素养目标理念.

关键词：电流任务驱动核心素养课程标准单元教学

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绿色施工技术在南沙会址项目中的应用

葛洲坝集团科技 2024年第1期 21-23,41页

作者：蒋汰宏中国葛洲坝集团建设工程有限公司云南昆明650217

文章以南沙国际金融论坛(IFF)永久会址项目创建省级绿色施工示范工程为例,从施工管理、“四节一环保”评价要素出发,展现绿色施工重点评价指标在项目具体实践应用中的实施情况、技术方法、施工措施及目标控制过程,为同类项目绿色施工实... 详细信息

文章以南沙国际金融论坛(IFF)永久会址项目创建省级绿色施工示范工程为例,从施工管理、“四节一环保”评价要素出发,展现绿色施工重点评价指标在项目具体实践应用中的实施情况、技术方法、施工措施及目标控制过程,为同类项目绿色施工实施提供参考。

关键词：绿色施工四节一环保评价指标

Optimal Operation of Turbo Blowers Serially Connected Using Inlet Vanes

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Journal of Thermal Science 2011年第1期20卷 26-31页

作者： Choon-Man jang Plant Research Division Korea Institute of Construction Technology1190 IIsanseo-GuGoyang-Si411-712Korea

Optimal operation of the turbo blowers having an inlet vane has been studied to understand the blowers' operating *** analyze three-dimensional flow field in the turbo blowers serially connected,general analysis code,CFX,is introduced in the present *** turbulence model is employed to estimate the eddy *** the numerical analysis,it is found that the flow rates of the turbo blowers can be controlled at the vane angle between 90 (full open condition) degrees and 60 degrees effectively,because pressure loss rapidly increases below 60 degree of a vane *** also has almost the same values from 90 degrees to 60 degrees of a vane *** is noted that the distorted inlet velocity generated in the small vane angle makes performance deterioration of the turbo blowers due to the local leading edge separation and the following non-uniform blade loading.

关键词： Turbo Blower Inlet Vane Refuse Collection System Efficiency Numerical Simulation

Iridium oxide fabrication and application: A review

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Journal of Energy Chemistry 2020年第7期29卷 152-172,I0005页

作者： Hansaem jang Jaeyoung Lee Electrochemical Reaction&Technology Laboratory(ERTL) School of Earth Sciences and Environmental EngineeringGwangju Institute of Science and Technology(GIST)Gwangju 61005Republic of Korea Ertl Center for Electrochemistry and Catalysis GRIGISTGwangju 61005Republic of Korea

Despite the scarcity and cost of iridium oxide,it is still the material of choice in numerous fields of science and applications,including capacitors,electrochromism,sensors,and various oxidation electrocatalysis(e.g.,chlorine evolution reaction,detoxification,and oxygen evolution reaction).Such versatility is attributed to the distinct features of iridium oxides,such as their activity,biocompatibility,conductivity,and *** features and properties of iridium oxides are strongly dependent on the fabrication *** this review,methodologies relating to the synthesis and fabrication of solid-state iridium oxides have been thoroughly collected and *** and crystallization techniques for iridium oxides are also *** the end of the review,the effects of utilizing a certain fabrication method on the characteristics of the iridium oxide product are recapitulated,together with the recommended application of the product in various fields.

关键词： Iridium oxide Iridium dioxide Electrode Electrocatalyst Electrochromism pH sensor Oxygen evolution reaction