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Journal of Zhejiang University-science B(Biomedicine & Biotechnology) 2023年第11期24卷 1037-1046页

作者： Yinan HE Yong WANG Yanqing ZHU Li jan LO MOE Key Laboratory for Molecular Animal Nutrition College of Animal SciencesZhejiang UniversityHangzhou310058China Pathology Department of Taizhou Hospital Zhejiang UniversityTaizhou317000China

The cell cycle consists of four distinct phases:GO/Gl,s(DNA synthesis),G2,and M(mitosis).The Gl to s transition is typified by an accumulation of 4',6-diamidino-2-phenylindole(DAPI)signal that indicates the rapid DNA ... 详细信息

关键词： synthesis initiated function

Lattice distortion releasing local surface strain on high-entropy alloys

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Nano Research 2022年第6期15卷 4775-4779页

作者： Christian M.Clausen Jack K.Pedersen Thomas A.A.Batchelor jan Rossmeisl Department of Chemistry University of Copenhagen2100 KøbenhavnØDenmark

High-entropy alloys(HEAs)have the potential to be a paradigm-shift for rational catalyst discovery but this new type of alloy requires a completely new approach to predict the surface *** addition to the ligand effect perturbing the surface–adsorbate bond,the random configuration of elements in the surface will also induce local strain effects due to the varying radii of neighboring *** modelling of HEA surface reactivity requires an estimate of this effect:To what degree is the adsorption of intermediates on these lattice distorted atomic environments affected by local strain?In this study,more than 3,500 density functional theory(DFT)calculated adsorption energies of*OH and*O adsorbed on the HEAs IrPdPtRhRu and AgAuCuPdPt are statistically analyzed with respect to the lattice constants of the alloys and the surfaces of each individual binding *** is found that the inherent distortion of the lattice structure in HEAs releases the local strain effect on the adsorption energy as the atomic environment surrounding the binding atom(s)settles into a relaxed *** is even observed to be true for clusters of atoms of which the sizes deviate significantly from the atomic environment in which they are *** elucidates an important aspect of binding site interaction with the neighboring atoms and thus constitutes a step towards a more accurate theoretical model of estimating the reactivity of HEA surfaces.

关键词： high-entropy alloys surface reactivity strain effect surface strain electrocatalysis oxygen reduction reaction

Perspectives on Future Power system Control Centers for Energy Transition

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Journal of Modern Power systems and Clean Energy 2022年第2期10卷 328-344页

作者： Antoine Marot Adrian Kelly Matija Naglic Vincent Barbesant Jochen Cremer Alexandru stefanov jan Viebahn Reseau de Transport d'Electricite ParisFrance Electric Power Research Institute DublinIreland TenneT Amhemthe Netherlands TU Delft Delftthe Netherlands

Today's power systems are seeing a paradigm shift under the energy transition,sparkled by the electrification of demand,digitalisation of systems,and an increasing share of decarbonated power *** of these changes have a direct impact on their control centers,forcing them to handle weather-based energy resources,new interconnections with neighbouring transmission networks,more markets,active distribution networks,micro-grids,and greater amounts of available ***,these changes have translated during the past decade to small,incremental changes,mostly centered on hardware,software,and human *** assert that more transformative changes are needed,especially regarding human-centered design approaches,to enable control room operators to manage the future power *** paper discusses the evolution of operators towards continuous operation planners,monitoring complex time horizons thanks to adequate real-time *** upcoming challenges as well as emerging technologies for power systems,we present our vision of a new evolutionary architecture for control centers,both at backend and frontend *** propose a unified hypervision scheme based on structured decision-making concepts,providing operators with proactive,collaborative,and effective decision support.

关键词： Artificial intelligence cyber-phvsical system decision-making digital architecture digital twin energy transition hypervision.

Amorphous Ge-sb-se-Te chalcogenide films fabrication for potential environmental sensing and nonlinear photonics

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Journal of Materiomics 2022年第5期8卷 1009-1019页

作者： Tomas Halenkovic Marion Baillieul jan Gutwirth Petr Nemec Virginie Nazabal Department of Graphic Arts and Photophysics Faculty of Chemical TechnologyUniversity of PardubiceStudentska 57353210PardubiceCzech Republic Univ Rennes CNRSISCR(Institut des Sciences Chimiques de Rennes)e UMR 6226F-35000RennesFrance

Quaternary Ge-sb-se-Te chalcogenide thin films were fabricated by rf magnetron sputtering from Ge_(19)sb_(17)se_(64-x)Te_(x)(x=5,10,15,20)sputtering targets in order to select appropriate compositions for infrared sensor and optical nonlinear *** influence of chemical composition and deposition parameters on the optical properties,structure and wettability was thus *** amorphous thin films seem to be constituted by selenide entities that can include tellurium atoms in variable proportion such as[Gese_(4-x)Te_(x)]and[sbse_(3-x)Te_(x)](x=0,1,2)and Ge(sb)-Ge(sb)bonds according to Raman *** angle measurements of the thin films showed values of 68e71for water and their surface energies in the range of~36e39 mJ$m-2 seem suitable for surface functionalization required for photonic sensor ***,the maximum nonlinearity at the telecom wavelength with respect to the highest figure of merit value was found for the thin film with composition Ge_(19)sb_(17)se56Te8 having nonlinear refractive index of 28×10^(-18) m2·W^(-1).Due to their low optical bandgap energies,they may find their full interest for nonlinear optics in the mid-infrared *** IR transparency in combination with high(non)linear refractive indices make these materials attractive in the field of midIR sensing and optical nonlinear devices.

关键词： Chalcogenide Thin films Glass Amorphous Optical properties NLO Contact angles sputtering Raman

New wormhole model with quasi-periodic oscillations exhibiting conformal motion in f(T,T)gravity

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Communications in Theoretical Physics 2023年第9期75卷 59-68页

作者： G Mustafa Abdelghani Errehymy s K Maurya Munsif jan Department of Physics Zhejiang Normal UniversityJinhua 321004China Astrophysics Research Centre School of MathematicsStatistics and Computer ScienceUniversity of KwaZulu-NatalPrivate Bag X54001Durban 4000South Africa Laboratory of High Energy Physics and Condensed Matter Department of PhysicsFaculty of Sciences Aïn ChockHassan II University of CasablancaB.P.5366 MaarifCasablanca 20100Morocco Department of Mathematical and Physical sciences College of Arts and ScienceUniversity of NizwaNizwaOman New Uzbekistan University Mustaqillik Ave.54Tashkent 100007Uzbekistan

This analysis explores the new wormhole(WH)solution in the background of teleparallel gravity with minimal matter *** complete this study,we consider the conformal symmetry with non-zero Killing *** exact shape function is computed by considering the linear equation of state with the phantom *** energy conditions are investigated for the calculated shape function with the equation of state *** presence of exotic matter is confirmed due to the violation of the null energy *** current study also explores the physical properties of the epicyclic frequencies with quasi-periodic *** the astrophysical,epicyclic frequencies are extensively employed to explore the self-gravitating *** is concluded that a stable WH solution is acceptable for WH geometry.

关键词： extended teleparallel theory wormhole solutions epicyclic frequencies conformal symmetry

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以患者为中心的临床试验理念及发展趋势探讨

中国新药杂志 2024年第13期33卷 1356-1361页

作者：方中坚沈家辉汪颖霞张亮樊玉录朱思琪邵蓉邵明立中国药科大学南京211198 上海健康医学院上海201318 东南大学附属南京胸科医院南京210029

以患者为中心的临床试验指的是一种将患者的需求和福祉放在首位的研究方法,这一概念强调了患者在临床试验中的核心作用,在医学领域获得了极大的关注。这种理念源于对现代医疗服务的深度反思,即我们的医疗系统是否真正关注和满足患者的需... 详细信息

以患者为中心的临床试验指的是一种将患者的需求和福祉放在首位的研究方法,这一概念强调了患者在临床试验中的核心作用,在医学领域获得了极大的关注。这种理念源于对现代医疗服务的深度反思,即我们的医疗系统是否真正关注和满足患者的需求,是否在医疗决策过程中足够重视患者的观点和期望。以患者为中心的临床试验的目标是确保患者在整个研究过程中得到足够的关注和尊重,同时也提高试验的质量和适用性。本文介绍了以患者为中心的临床试验理念的概述以及重点领域,探讨了当前所面临的挑战,旨在提高研究者对于该理念的认识。

关键词：临床试验以患者为中心临床结果评估患者参与

Polymersomes:From Macromolecular self-Assembly to Particle Assembly

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Chinese Journal of Chemistry 2022年第15期40卷 1842-1855页

作者： Jiamin Zhang Jinhui Jiang sha Lin Erik jan Cornel Chang Li Jjianzhong Du Department of Polymeric Materials Schoolof Materials Science and EngineeringTongji University4800 Caoan RoadShanghai 201804China Department of Gynaecology and Obstetrics Shanghai Fourth People's HospitalSchool of MedicineTongji UniversityShanghai 200434China

What is the most favorite and original chemistry developed in your research group?Ring-opening polymerization-induced self-assembly of N-carboxyanhydrides(NCA-PIsA),and fusion-induced particle assembly(FIPA).How do you get into this specific field?Could you please share some experiences with our readers?NCA-PIsA was developed to solve the biodegradability problem of nanoparticles by traditional PIsA,while FIPA was inspired by nature.

关键词： Polymersomes(polymer vesicles) Nanoparticles Biomedical applications Macromolecular self-assembly Polymerization-induced self-assembly Particle assembly

Three-dimensional modeling in complex liver surgery and liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 318-324页

作者： Jian-Peng Liu jan Lerut Zhe Yang Ze-Kuan Li shu-sen Zheng Department of Hepatobiliary and Pancreatic surgery Department of Liver TransplantationShulan(Hangzhou)HospitalZhejiang Shuren University School of MedicineHangzhou 310000China starzl Unit of Abdominal Transplantation University Hospitals Saint LucUniversitécatholique LouvainBrusselsBelgium Division of Hepatobiliary Pancreatic surgery the First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China National Clinical Research Center of Infectious Diseases Hangzhou 310003China

Liver resection and transplantation are the most effective therapies for many hepatobiliary tumors and ***,these surgical procedures are challenging due to the anatomic complexity and many anatomical variations of the vascular and biliary ***-dimensional(3D)printing models can clearly locate and describe blood vessels,bile ducts and tumors,calculate both liver and residual liver volumes,and finally predict the functional status of the liver after resection *** 3D printing models may be particularly helpful in the preoperative evaluation and surgical planning of especially complex liver resection and transplantation,allowing to possibly increase resectability rates and reduce postoperative *** the continuous developments of imaging techniques,such models are expected to become widely applied in clinical practice.

关键词： 3D printing models Liver surgery Liver transplantation

The role of zonal flows in reactive fluid closures

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Plasma science and Technology 2018年第7期20卷 41-49页

作者： jan weiland chalmers university of technology and euratom-vr association SE-41296 GothenburgSweden

We will give an overview of results obtained by our reactive fluid model. It is characterised as a fluid model where all moments with sources in the experiment are kept. Furthermore, full account is taken for the highest moments appearing in unexpanded denominators also including full toroidicity. It has been demonstrated that the strength of zonal flows is dramatically larger in reactive fluid closures than in those which involve dissipation. This gives a direct connection between the fluid closure and the level of excitation of turbulence. This is because zonal flows are needed to absorb the inverse cascade in quasi 2D turbulence. This also explains the similarity in structure of the transport coefficients in our model with a reactive closure in the energy equation and models which have a reactive closure because of zero ion temperature such as the Hasegawa-Wakatani model. Our exact reactive closure unifies several well-known features of tokamak experiments such as the L-H transition, internal transport barriers and the nonlinear Dimits upshift of the critical gradient for onset of transport. It also gives transport of the same level as that in nonlinear gyrokinetic codes. since these include the kinetic resonance this confirms the validity of the thermodynamic properties of our model. Furthermore, we can show that while a strongly nonlinear model is needed in kinetic theory a quasilinear model is sufficient in the fluid description. Thus our quasilinear fluid model will be adequate for treating all relevant problems in bulk transport. This is finally confirmed by the reproduction by the model of the experimental power scaling of the confinement time Te ~ P-2/3. This confirms the validity of our reactive fluid model. This also gives credibility to our ITER simulations including the H-mode barrier. A new result is here, that alpha heating strongly reduces the slope of the H-mode barrier. This should significantly reduce the effects of ELM＇s.

关键词： turbulent transport improved mixing length estimates zonal flows toroidicity

Three-dimensional virtual representation for the whole process of dam-break floods from a geospatial storytelling perspective

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International Journal of Digital Earth 2022年第1期15卷 1637-1656页

作者： Weilian Li Jun Zhu jan-Henrik Haunert Lin Fu Qing Zhu Youness Dehbi Faculty of Geosciences and Environmental Engineering Southwest Jiaotong UniversityChengduPeople's Republic of China Institute of Geodesy and Geoinformation University of BonnBonnGermany

The objective of disaster scenes is to share location-based risk information to a large audience in an effective and intuitive ***,current studies on three-dimensional(3D)representation for dam-break floods have the following limitations:(1)they are lacking a reasonable logic to organize the whole process of dam-break floods,(2)they present information in a way that cannot be easily understood by *** storytelling helps to create exciting experiences and to explain complex relationships of geospatial *** article proposes a three-dimensional virtual representation method for the whole process of dam-break floods from a geospatial storytelling *** creation of a storyline and a storytelling-oriented representation of dam-break floods are discussed in ***,a prototype system based on WebGL is developed to conduct an experiment *** results of the experiment show that the proposed method can effectively support 3D representation of the spatiotemporal process of dam-break ***,the statistical results indicate that the storytelling is useful for assisting participants in understanding the occurrence and development of dam-break floods,and is applicable to the popularization of disaster science for the general public.

关键词： Geospatial storytelling dam-break flood spatiotemporal process virtual representation 3D scene