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静脉注射曲马多与硬膜外吗啡缓解胸廓切开术后疼痛的比较:安慰剂对照的双盲试验

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中国疼痛医学杂志 2003年第2期9卷 125-128页

作者： Michael F.M.james PhD FRCA Sylvia A.M.heijke FFA(SA) Peter C.Gordon FFA(SA) Department of Anaesthesia University of Cape TownSouth AfricaDepartment of AnaesthesiaUniversity of Cape TownSouth AfricaDepartment of AnaesthesiaUniversity of Cape TownSouth AfricaDepartment of AnaesthesiaUniversity of Cape TownSouth AfricaDepartment of AnaesthesiaUniversity of Cape TownSouth AfricaDepartment of AnaesthesiaUniversity of Cape TownSouth AfricaDepartment of AnaesthesiaUniversity of Cape TownSouth Africa

曲马多可以缓解术后疼痛且导致呼吸抑制的危险性很小,其镇痛作用机理仅部分在于其所具有的阿片激动剂活性,因而我们研究了曲马多对胸廓切开术后疼痛的缓解作用.在这项随机双盲的试验中,单次快速静脉注射150mg曲马多(T组)与硬膜外注射吗... 详细信息

曲马多可以缓解术后疼痛且导致呼吸抑制的危险性很小,其镇痛作用机理仅部分在于其所具有的阿片激动剂活性,因而我们研究了曲马多对胸廓切开术后疼痛的缓解作用.在这项随机双盲的试验中,单次快速静脉注射150mg曲马多(T组)与硬膜外注射吗啡相比较,首剂量为2mg,之后按0.2mg/h的速度持续注射(M组).每组患者可以通过病人自控镇痛(PCA)泵静脉注射吗啡.手术后定时记录疼痛评分、吗啡的消耗量、动脉血气、肺活量直至术后第一天的早8:00.两组患者的疼痛都得到了充分的缓解,两组间疼痛评分和PCA吗啡消耗量没有差别.术后2小时T组的动脉氧分压(PaO2)显著高于M组,而术后4小时M组的动脉二氧化碳分压(PaCO2)显著高于T组,其他呼吸上的差异不显著.我们认为,手术结束时单次给150mg曲马多与硬膜外注射吗啡在术后早期具有相同的镇痛效果.

关键词：曲马多硬膜外注射镇痛效果硬膜外腔注射阿片吗啡硬膜外静脉注射术后疼痛

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雷克萨斯GS 450h

汽车杂志 2005年第5期 57-57页

作者： james

在刚推出混合动力豪华SUV RX400h后不到两个月，雷克萨斯在纽约车展中推出一款混合动力豪华轿车GS450h，定于2006年春在美国上市。

关键词： GS 混合动力豪华SUV 2006年豪华轿车纽约车展推出

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宝马 h2R

汽车杂志 2004年第11期 46-46页

作者： james

氢作为高效能源已超越了火箭上的应用，宝马用一部以氢内燃机驱动的汽车创造了9项速度纪录，这部车被命名为h2R，意为氢赛车，这次测试在法国Miramas的高速试验场举行。

关键词： “宝马h2R”氢赛车汽车燃料车型技术参数外观设计装备配置

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建造詹姆斯·韦布空间望远镜

中国国家天文 2021年第11期15卷 36-47页

作者：保罗·h.盖特纳李海宁(译) 不详中国科学院国家天文台星云

作为在建的下一代望远镜,詹姆斯·韦布空间望远镜是科学视野、技术进步和工程成就的综合产物。望远镜是强劲的探索工具,使人类能够探测到远超出自己或凭借机器人所能到达的地方。可以说,迄今为止,没有什么仪器能比詹姆斯·韦布空间望远... 详细信息

作为在建的下一代望远镜,詹姆斯·韦布空间望远镜是科学视野、技术进步和工程成就的综合产物。望远镜是强劲的探索工具,使人类能够探测到远超出自己或凭借机器人所能到达的地方。可以说,迄今为止,没有什么仪器能比詹姆斯·韦布空间望远镜更能展现由人类对宇宙的好奇心所带来的进步。韦布是人们期待已久的、哈勃空间望远镜的科学继任者,它有望成为世界上首屈一指的空间科学天文台。

关键词：空间望远镜空间科学继任者机器人韦布詹姆斯好奇心天文台

进食天然富含ω-3多不饱和脂肪酸食物后的ω-3指数和血压反应:一项随机对照试验

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中华高血压杂志 2021年第1期29卷 76-76页

作者：袁源(摘译) 练桂丽(审校) Stanton AV james K Brennan MM O’Donovan F Buskandar F Shortall K El-Sayed T Kennedy J hayes h Fahey AG Pender N Thom SAM Moran N Williams DJ Dolan E 不详

缺乏ω-3多不饱和脂肪酸(polyunsaturated fatty acids,PUFAs)的膳食很普遍。这种膳食近期被列为第六大膳食危险因素。缺乏PUFAs导致全球150万例死亡和330万伤残调整生命年。野生油性鱼的贮存量不足以供给全球人口,饲养鱼二十碳五烯酸... 详细信息

缺乏ω-3多不饱和脂肪酸(polyunsaturated fatty acids,PUFAs)的膳食很普遍。这种膳食近期被列为第六大膳食危险因素。缺乏PUFAs导致全球150万例死亡和330万伤残调整生命年。野生油性鱼的贮存量不足以供给全球人口,饲养鱼二十碳五烯酸和二十二碳六烯酸(docosahexaenoic acid,DhA)水平在过去20年减少过半。该研究报道一项双盲对照试验,其中161名正常血压的健康成年人随机分配食用富含ω-3PUFAs(或对照)的鸡肉至少3份/周,和食用富含ω-3PUFAs(或对照)的鸡蛋至少3份/周,持续6个月。

关键词：伤残调整生命年正常血压二十二碳六烯酸二十碳五烯酸健康成年人贮存量随机对照试验 PUFAs

Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up

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World Journal of Psychiatry 2015年第4期5卷 412-424页

作者： Ahmed Z Elmaadawi Peter S Jensen L Eugene Arnold Brooke SG Molina Lily hechtman howard B Abikoff Stephen P hinshaw Jeffrey h Newcorn Laurence Lee Greenhill james M Swanson Cathryn A Galanter Department of Psychiatry Indiana University School of Medicine-South Bend Campus REACh Institute Department of Psychiatry Ohio State University Department of Psychiatry University of Pittsburgh Department of Psychiatry and Pediatrics McGill University Health Center Department of Child and Adolescent Psychiatry The Child Study Center at NYU Langone Medical Center Department of Psychology University of California Department of Psychiatry and Pediatrics Icahn School of Medicine at Mount Sinai Department of Clinical Child and Adolescent Psychiatry New York Psychiatric Institute Department of Pediatrics and Epidemiology Child Development Center University of California Department of Psychiatry State University of New York Downstate Medical Center and Kings County Hospital Center

AIM: To determine the prevalence of bipolar disorder(BD) and sub-threshold symptoms in children with attention deficit hyperactivity disorder(ADhD) through 14 years' follow-up, when participants were between 21-24 years ***: First, we examined rates of BD type Ⅰ?and Ⅱ diagnoses in youth participating in the NIMh-funded Multimodal Treatment Study of ADhD(MTA). We used the diagnostic interview schedule for children(DISC), administered to both parents(DISC-P) and youth(DISCY). We compared the MTA study subjects with ADhD(n = 579) to a local normative comparison group(LNCG, n = 289) at 4 different assessment points: 6, 8, 12, and 14 years of follow-ups. To evaluate the bipolar variants, we compared total symptom counts(TSC) of DSM manic and hypomanic symptoms that were generated by DISC in ADhD and LNCG subjects. Then we sub-divided the TSC into pathognomonic manic(PM) and non-specific manic(NSM) symptoms. We compared the PM and NSM in ADhD and LNCG at each assessment point and over time. We also evaluated the irritability as category A2 manic symptom in both groups and over time. Finally, we studied the irritability symptom in correlation with PM and NSM in ADhD and LNCG ***: DISC-generated BD diagnosis did not differ significantly in rates between ADhD(1.89%) and LNCG 1.38%). Interestingly, no participant met BD diagnosis more than once in the 4 assessment points in 14 years. however, on the symptom level, ADhD subjects reported significantly higher mean TSC scores: ADhD 3.0; LNCG 1.7; P hD status was associated with higher mean NSM: ADhD 2.0 vs LNCG 1.1; P hD subjects had higher PM symptoms than LNCG, with PM means over all time points of 1.3 ADhD; 0.9 LNCG; P = 0.0001. Examining both NSM and PM, ADhD status associated with greater NSM than PM. however, Over 14 years, the NSM symptoms declined and changed to PM over time(df 3, 2523; F = 20.1; P < 0.0001). Finally, Irritability(BD DSM criterion-A2) rates were significa

关键词： Multimodal treatment study of attention deficit hyperactivity disorder Irritability Attention deficit hyperactivity disorder Diagnostic interview schedule for children Bipolar disorder

不同维度的对苯二甲酸锌配合物的固体核磁共振研究

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不同维度的对苯二甲酸锌配合物的固体核磁共振研究

Robotic versus laparoscopic liver resection for huge (≥10 cm) liver tumors: an international multicenter propensity-score matched cohort study of 799 cases

第十六届全国波谱学学术会议

作者：袁文兵 Stuart L james 张岐贾春满王道龙王霹霹海南省精细化工重点实验室海南大学 School of Chemistry and Chemical Engineering Queen's University Belfast

＜正＞我们研究了基于对苯二甲酸锌的三个不同维度的配合物的固体核磁:一维化合物1（剑桥晶体数据库（CSD）编号:DIKQET）,二维化合物2（CSD编号:GECXUh）和三维化合物3（CSD编号:IFABIA）。化合物1中,1h NMR:δ7.38ppm;13C NMR:δ131.3,

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hepatobiliary Surgery and Nutrition 2023年第2期12卷 205-215,I0005页

作者： Tan-To Cheung Rong Liu Federica Cipriani Xiaoying Wang Mikhail Efanov David Fuks Gi-hong Choi Nicholas L.Syn Charing C.N.Chong Fabrizio Di Benedetto Ricardo Robles-Campos Vincenzo Mazzaferro Fernando Rotellar Santiago Lopez-Ben james O.Park Alejandro Mejia Iswanto Sucandy Adrian K.h.Chiow Marco V.Marino Mikel Gastaca Jae hoon Lee TPeter Kingham Mathieu D’hondt Sung hoon Choi Robert P.Sutcliffe ho-Seong han Chung-Ngai Tang Johann Pratschke Roberto I.Troisi Go Wakabayashi Daniel Cherqui Felice Giuliante Davit L.Aghayan Bjorn Edwin Olivier Scatton Atsushi Sugioka Tran Cong Duy Long Constantino Fondevila Mohammad Abu hilal Andrea Ruzzenente Alessandro Ferrero Paulo herman Kuo-hsin Chen Luca Aldrighetti Brian K.P.Goh International robotic and laparoscopic liver resection study group investigators Department of Surgery Queen Mary HospitalThe University of Hong KongHong Kong SARChina Faculty of hepatopancreatobiliary Surgery The First Medical Center of Chinese People’s Liberation Army(PLA)General HospitalBeijingChina hepatobiliary Surgery Division IRCCS San Raffaele HospitalMilanItaly Department of Liver Surgery and Transplantation Liver Cancer InstituteZhongshan HospitalFudan UniversityShanghaiChina Department of hepato-Pancreato-Biliary Surgery Moscow Clinical Scientific CenterMoscowRussia Department of Digestive Oncologic and Metabolic SurgeryInstitute Mutualiste MontsourisUniversite Paris DescartesParisFrance Division of hepatopancreatobiliary Surgery Department of SurgerySeverance HospitalYonsei University College of MedicineSeoulKorea Department of hepatopancreatobiliary and Transplant Surgery Singapore General Hospital and Yong Loo Lin School of MedicineNational University of SingaporeSingaporeSingapore Division of hepatobiliary and Pancreatic Surgery Department of SurgeryPrince of Wales HospitalThe Chinese University of Hong KongHong Kong SARChina hPB Surgery and Liver Transplant Unit University of Modena and Reggio EmiliaModenaItaly Department of General Visceral and Transplantation SurgeryClinic and University Hospital Virgen de la ArrixacaIMIB-ARRIXACAMurciaSpain hPB Surgery Hepatology and Liver TransplantationFondazione IRCCS Istituto Nazionale Tumori di MilanoMilanItaly hPB and Liver Transplant Unit Department of General SurgeryClinica Universidad de NavarraUniversidad de NavarraPamplonaSpain Institute of health Research of Navarra(IdisNA) PamplonaSpain hepatobiliary and Pancreatic Surgery Unit Department of SurgeryDr.Josep Trueta HospitalIdIBGiGironaSpain hepatobiliary Surgical Oncology Department of SurgeryUniversity of Washington Medical CenterSeattleWAUSA The Liver Institute Methodist Dallas Medical CenterDallasTXUSA Adventhealth Tampa Digestive Health InstituteTampaFLUSA hepatopancreatobiliary Unit Department of SurgeryChangi General

Background:The use of laparoscopic(LLR)and robotic liver resections(RLR)has been safely performed in many institutions for liver tumours.A large scale international multicenter study would provide stronger evidence and insight into application of these techniques for huge liver tumours≥10 ***:This was a retrospective review of 971 patients who underwent LLR and RLR for huge(≥10 cm)tumors at 42 international centers between ***:One hundred RLR and 699 LLR which met study criteria were *** comparison between the 2 approaches for patients with huge tumors were performed using 1:3 propensity-score matching(PSM)(73 vs.219).Before PSM,LLR was associated with significantly increased frequency of previous abdominal surgery,malignant pathology,liver cirrhosis and increased median *** PSM,RLR and LLR was associated with no significant difference in key perioperative outcomes including media operation time(242 vs.290 min,P=0.286),transfusion rate rate(19.2%vs.16.9%,P=0.652),median blood loss(200 vs.300 mL,P=0.694),open conversion rate(8.2%vs.11.0%,P=0.519),morbidity(28.8%vs.21.9%,P=0.221),major morbidity(4.1%vs.9.6%,P=0.152),mortality and postoperative length of stay(6 vs.6 days,P=0.435).Conclusions:RLR and LLR can be performed safely for selected patients with huge liver tumours with excellent *** was no significant difference in perioperative outcomes after RLR or LLR.

关键词： Laparoscopic liver resection(LLR) robotic liver resection(RLR) hepatocellular carcinoma colorectal liver metastases huge

Efficiency and patient experience with propofol vsconventional sedation:A prospective study

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World Journal of Gastrointestinal Endoscopy 2016年第4期8卷 232-238页

作者： Patrick Thornley Mohammad Al Beshir james Gregor Andreas Antoniou Nitin Khanna Michael G.DeGroote School of Medicine MsMaster UniversityHamiltonOntario L8S 4L8Canada Division of Gastroenterology King Fahad Specialist Hospital-DammamDammam 31444Saudi Arabia Division of Gastroenterology Western UniversityLondonOntario N6A 3K7Canada Department of Anesthesia and Perioperative Medicine Western UniversityLondonOntario N6A 3K7Canada

AIM: To determine whether anaesthesiologistadministered sedation with propofol(AAP) or endoscopist-administered conscious sedation(EAC) with fentanyl/midazolam shortens colonoscopy duration/total room time. METhODS: This is a prospective, non-randomized, comparative study that enrolled patients greater than 18 years of age undergoing colonoscopy in a single Canadian academic outpatient endoscopy unit over a three-month consecutive period. Colonoscopies in this unit are performed both with AAP and EAC. Patient demographics, procedure-related data and adverse events were documented. Additionally, the level of procedure difficulty, and whether a staff endoscopist, trainee with assistance, or independent trainee, performed the procedure were documented. A validated modified 4-question, 5-point Likert scale telephone survey was used to assess patient satisfaction with colonoscopy. The telephone patient satisfaction survey was conducted 24-72 h following the ***: Two hundred and thirty patients were enrolled during the study period with 126 patients in the AAP group and 104 patients in the EAC group. Mean procedure time was 18.3 ± 10.1 min in the AAP group and 14.7 ± 7.1 min in the EAC group(P = 0.002). Mean total room time was 36.8 ± 13.7 with AAP and 30.1 ± 11 min with EAC(P he use of AAP(P = 0.002), resident participation(P herapeutic interventions(P hesiologist class(P = 0.016), to be predictors of longer total room time. Patient age and gender were not significant predictors. After excluding cases in which trainees were involved, there was no significant difference in procedure time between the two groups(P = 0.941), however total room time was still prolonged in the AAP group(P = 0.019). The amount of pain experienced was lower with AAP(P = 0.02), with a trend toward overall higher patient sa

关键词： Patient satisfaction Fentanyl Colonoscopy Midazolam Propofol