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THE TIME INTErVAL ALIGNMENT (IA) POLICIES, BOUNDArY AND APPLICATIONS WITH MULTIPLE STrEAM ArrIVALS

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Journal of Systems Science and Systems Engineering 2011年第4期20卷 400-415页

作者： Meimei WANG james r. PErKINS Decision Support Information System Beth Israel Deaconess Medical Center Boston MA 02120 USA Department of Manufacturing Engineering Boston University Boston MA 02446 USA

This paper discusses a class of interval alignment （IA） scheduling policies, which are particularly effective for the systems that do not have Markovian structure. The numerical results show that IA policies effectively smooth part flows, improve performance and decrease average Work-in-Process （WlP） by adding intermediate delays to the system, The boundary of IA policy is proven and the applications of IA policy in the system with multiple stream arrivals have been discussed. With the combination of release policy, it is practical to implement IA to multiple stream arrival system.

关键词： Detailed scheduling policies non-Markovian multiple stream interval alignment policies integer linear programming lea

Quantum feedback networks and control:A brief survey

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Chinese Science Bulletin 2012年第18期57卷 2200-2214页

作者： james Matthew r ArC Centre for Quantum Computation and Communication Technology Research School of EngineeringAustralian National UniversityCanberraACT 0200Australia

The purpose of this paper is to provide a brief review of some recent developments in quantum feedback networks and control.A quantum feedback network (QFN) is an interconnected system consisting of open quantum systems linked by free fields and/or direct physical *** network constructs,including series connections as well as feedback loops,are *** quantum feedback network theory provides a natural framework for analysis and *** properties such as dissipation,stability,passivity and gain of open quantum systems are *** system design is also discussed,primarily in the context of open linear quantum stochastic *** issue of physical realizability is discussed,and explicit criteria for stability,positive real lemma,and bounded real lemma are *** for linear quantum systems,coherent H∞ and LQG control are described.

关键词：开放量子系统反馈网络控制系统有界实引理 LQG控制网络结构反馈回路网络理论

Compressing local atomic neighbourhood descriptors

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npj Computational Materials 2022年第1期8卷 1593-1605页

作者： james P.Darby james r.Kermode Gábor Csányi Engineering Dept University of CambridgeTrumpington StCambridgeCB21PZUK Warwick Centre for Predictive Modelling School of EngineeringUniversity of WarwickCoventryCV47ALUK

Many atomic descriptors are currently limited by their unfavourable scaling with the number of chemical elements S *** length of body-ordered descriptors,such as the SOAP power spectrum(3-body)and the(ACE)(multiple body-orders),scales as(NS)^(ν)whereν+1 is the body-order and N is the number of radial basis functions used in the density *** introduce two distinct approaches which can be used to overcome this scaling for the SOAP power ***,we show that the power spectrum is amenable to lossless compression with respect to both S and N,so that the descriptor length can be reduced from O(N^(2)S^(2))to O(NS).Secondly,we introduce a generalised SOAP kernel,where compression is achieved through the use of the total,element agnostic density,in combination with radial *** ideas used in the generalised kernel are equally applicably to any other body-ordered descriptors and we demonstrate this for the(ACSF).

关键词： SOAP scaling kernel

Matrilinear hierarchy in the American black bear (Ursus americanus)

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Integrative Zoology 2022年第1期17卷 139-155页

作者： Benjamin KILHAM james r.SPOTILA Kilham Bear Center LymeNew HampshireUSA Department of Biodiversity Earth and Environmental ScienceDrexel UniversityPhiladelphiaPennsylvaniaUSA

The American black bear(Ursus americanus)was long thought to be solitary and its social organization has not been well ***,we present new data on black bear social *** objectives of the study were to make detailed observations of the behavior of wild black bears to determine their social interactions and *** tested whether black bears interacted socially beyond mating and competing for resources,if black bears tracked relationships and interacted regularly even when resources were not limited,and whether the social structure of a population of black bears was based on a matrilinear *** collected data by direct observation of bears from 1993 to *** of 1210 social interactions at a provisioning site indicated that females compete and form matrilinear *** bears established a hierarchy for food,control of space,and control of younger *** interaction scent marking took place,which suggested that dominant females were conditioning subordinates to their scent *** behavior occurred between related and unrelated bears and helped to establish the social structure of the bear *** on our data,human–bear conflicts can be reduced by behavioral modifications by humans when they encounter *** of bear behavior and the matrilinear hierarchy provide a basis for non-lethal management of bears that find themselves in a bear–human conflict situation.

关键词： bear matrilinear hierarchy New Hampshire rank social behavior Ursus

Is activation of GDNF/rET signaling the answer for successful treatment of Parkinson's disease?A discussion of data from the culture dish to the clinic

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Neural regeneration research 2022年第7期17卷 1462-1467页

作者： james A.Conway Edgar r.Kramer Institute of Translational and Stratified Medicine Peninsula Medical SchoolFaculty of HealthUniversity of PlymouthDevonUK

The neurotrophic signaling of glial cell line-derived neurotrophic factor(GDNF)with its canonical receptor,the receptor tyrosine kinase rET,coupled together with the GDNF family receptor alpha 1 is important for dopaminergic neuron survival and physiology in cell culture experiments and animal *** prompted the idea to try GDNF/rET signaling as a therapeutic approach to treat Parkinson’s disease with the hallmark of dopaminergic cell death in the substantia nigra of the *** several clinical trials with GDNF in Parkinson’s disease patients,which mainly focused on optimizing the GDNF delivery technique,benefits were only seen in a few *** general,the endpoints did not show significant *** suggests that it will be helpful to learn more about the basic biology of this fascinating but complicated GDNF/rET signaling system in the dopaminergic midbrain and about recent developments in the field to facilitate its use in the *** we will refer to the latest publications and point out important open questions in the field.

关键词： α-synuclein clinical trials dopaminergic neurons glial cell line-derived neurotrophic factor GFrα1 gut-brain axis Nedd4 Parkin Parkinson’s disease rET

Effect of wall rougheners on cross-sectional flow characteristics for non-spherical particles in a horizontal rotating cylinder

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Particuology 2014年第1期12卷 44-53页

作者： Guang Lu james r.Third Christoph r.Müller ETH Zürich Department of Mechanical and Process Engineering Institute of Energy Technology Laboratory of Energy Science and Engineering8092 Zürich Switzerland

Discrete-element-method （DEM） simulations have been performed to investigate the cross-sectional flow of non-spherical particles in horizontal rotating cylinders with and without wall rougheners. The non-spherical particles were modeled using the three-dimensional super-quadric equation. The influence of wall rougheners on flow behavior of grains was studied for increasing particle blockiness. Moreover, for approximately cubic particles （squareness parameters [555]）, the rotational speed, gravitational acceleration and particle size were altered to investigate the effect of wall rougheners under a range of operating conditions. For spherical and near-spherical particles （approximately up to the squareness parameters [344]）, wall rougheners are necessary to prevent slippage of the bed against the cylinder wall. For highly cubic particle geometries （squareness parameters larger than [3441）, wall rougheners resulted in a counter-intuitive decrease in the angle of repose of the bed. In addition, wall rougheners employed in this study were demonstrated to have a higher impact on bed dynamics at higher rotational speeds and lower gravitational accelerations. Nevertheless, using wall rougheners had a comparatively small influence on particle-flow characteristics for a bed composed of finer grains.

关键词： Granular flowNon-spherical particlesrotating cylinderDiscrete element method (DEM)Kiln

The Effability of Semantic relations:Describing Attitude

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外国语 2020年第6期43卷 2-20页

作者： james r.Martin Department of Linguistics University of SydneySydneyNSW 2006AustraliaMartin Centre for Appliable LinguisticsShanghai Jiao Tong UniversityShanghai 200240China

This paper explores some aspects of the problem of developing terminology for attitudinal relations in English,as part of a description of evaluation informed by systemic functional linguistics(SFL)-*** reviews the relational theory of meaning underpinning the description and key dimensions of the Systemic Functional Linguistic theory from which the description is *** issues in the selection of terms and presentation of APPrAISAL systems are then discussed,and suggestions canvassed for possible *** paper highlights the possibilities and challenges involved in naming and presenting semantic relations in descriptions using SFL as their informing theory.

关键词： appraisal attitude ineffability terminology valeur axis

Biomaterials for refractive correction:corneal onlays and inlays

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Science China Chemistry 2014年第4期57卷 501-509页

作者： WU Jian FUNDErBUrGH james L WAGNEr William r McGowan Institute for regenerative Medicine University of Pittsburgh Department of Surgery University of Pittsburgh School of Medicine Department of Ophthalmology University of Pittsburgh School of Medicine Department of Bioengineering University of Pittsburgh

Corneal inlays and onlays represent a means of providing patients with permanent refractive error correction. As an alternative to conventional spectacles and contact lens, these techniques are less invasive compared with laser-based refractive surgery and are reversible. In this review, we provide a brief overview of the anatomic microstructure of the human cornea, indicating the primary physiological function for each component. Next, the wide range of biomaterials used as corneal inlays and onlays are considered, from synthetic polymers to biological components derived from the extracellular matrix. The limitations and challenges associated with the most common materials are discussed as is the need to improve their properties to achieve long-term, complication-free intraocular implantation. Finally, the prospect of applying tissue engineering strategies is noted for its potential to generate autologous corneal tissue that could be implanted as the optimal inlay or onlay materials.

关键词： refractive error onlays inlays synthetic polymer biological extracellular matrix refractive surgery

Heme oxygenase system in hepatic ischemia-reperfusion injury

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World Journal of Gastroenterology 2010年第48期16卷 6068-6078页

作者： james A richards Stephen J Wigmore Luke r Devey Centre for Inflammation research The University of EdinburghThe Queen's Medical Research Institute

Hepatic ischemia-reperfusion injury (IrI) limits access to transplantation. Heme oxygenase-1 (HO-1) is a powerful antioxidant enzyme which degrades free heme into biliverdin,free iron and carbon monoxide. HO-1 and its metabolites have the ability to modulate a wide variety of inflammatory disorders including hepatic IrI. Mechanisms of this protective effect include reduction of oxygen free radicals,alteration of macrophage and T cell phenotype. Further work is required to understand the physiological importance of the many actions of HO-1 identified experimentally,and to harness the protective effect of HO-1 for therapeutic potential.

关键词： Ischemia-reperfusion injury Heme oxygenase Transplantation Ischemic pre-conditioning