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Regionalization of epididymal duct and epithelium in rats and mice by automatic computer-aided morphometric analysis

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Asian Journal of Andrology 2005年第3期7卷 267-275,页

作者： C.soler J.J.deMonserrat M.Núez R.Gutiérrez J.Núez M.sancho T.G.cooper Departmentof Functional Biology and Physical Anthropology University of ValènciaValència 46112Spain Departamentode Ouímica y Biología Universidad del NorteBarranquillaColombia Instituteof Reproductive Medicine University of MünsterMünster D-48129Germany

Aim： To establish a rat and mouse epididymal map based on the use of the Epiquatre automatic software for histologic image analysis. Methods： Epididymides from five adult rats and five adult mice were fixed in alcoholic Bouin＇s fixative and embedded in paraffin. serial longitudinal sections through the medial aspect of the organ were cut at 10 jam and stained with hematoxylin and eosin. As determined from major connective tissue septa, nine subdivisions of the rat epididymis and seven for the mouse were determined, consisting of five sub-regions in the caput （rat and mouse）, one （mouse） or three （rat） in the corpus and one in the cauda （rat and mouse）. Using the Epiquatre software, several tubular, luminal and epithelial morphometric parameters were evaluated. Results： statistical comparison of the quantitative parameters revealed regional differences （2-5 in the rat, 3-6 in the mouse, dependent on parameters） with caput regions 1 and 2 being largely distinguishable from the similar remaining caput and corpus, which were in turn recognizable from the cauda regions in both species. Conclusion： The use of the Epiquatre software allowed us to establish regression curves for different morphometric parameters that can permit the detection of changes in their values under different pathological or experimental conditions. （Asian J Androl 2005 sep; 7： 267-275）

关键词： rat mouse epididymis morphometry zonation computer-aided image analysis Epiquatre software

澳大利亚库珀盆地二叠系Roseneath组与Murteree组页岩矿物模拟及岩石物性参数

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石油勘探与开发 2016年第2期43卷 253-260页

作者： JADOON Quaid Khan ROBERTs eric BLENKINsOP Tom WUsT RaphaeI sHAH syed Anjum Department of Earth and Oceans James Cook University TRICAN Geological solutions Ltd saif Energy Limited

以澳大利亚库珀盆地二叠系Roseneath组和Muteree组页岩样品及测井数据为基础,综合利用地球化学分析、测井解释和岩心分析技术对Roseneath组和Muteree组页岩进行矿物模拟及岩石物性参数研究,评估这两套页岩的页岩气资源潜力。综合岩心和... 详细信息

以澳大利亚库珀盆地二叠系Roseneath组和Muteree组页岩样品及测井数据为基础,综合利用地球化学分析、测井解释和岩心分析技术对Roseneath组和Muteree组页岩进行矿物模拟及岩石物性参数研究,评估这两套页岩的页岩气资源潜力。综合岩心和岩屑样品分析得到的沉积学、岩相学、扫描电镜(sEM)和X射线衍射(XRD)数据,建立目的层矿物模型;基于岩心和岩屑的常规岩心分析结果、伽马测井资料、扫描电镜分析结果、XRD分析结果、地球化学和岩相学分析结果,针对关键井进行岩石物理建模。利用所建模型对两套页岩进行矿物成分模拟和岩石物性参数分析。Roseneath组页岩和Murteree组页岩均由黏土、石英、碳酸盐和干酪根组成,还含有少量副矿物,如长石、菱铁矿等。根据孔隙度、渗透率、TOC、含水饱和度、矿物组成等结果判断,Murteree组页岩在盆地范围内的资源潜力比Roseneath组页岩更好,潜力区在Encounter 1井区及其周边地区。

关键词：页岩气页岩矿物模拟岩石物性库珀盆地二叠系Roseneath组二叠系Murteree组

扩展型企业网络:ATM在新的业务模式中的重要地位

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信息系统工程 1998年第8期11卷 60-60页

作者： eric cooper FORE系统公司

网络设计者们再次受到新技术的冲击——而有些新技术只有在将来才可能实现。然而用户现在就要求更多的功能和增强的服务。今天在园区网核心里的决策,今后几年会波及到企业,正如早些时候LAN的决策已在当前的网络基础设施中实施一样。如... 详细信息

网络设计者们再次受到新技术的冲击——而有些新技术只有在将来才可能实现。然而用户现在就要求更多的功能和增强的服务。今天在园区网核心里的决策,今后几年会波及到企业,正如早些时候LAN的决策已在当前的网络基础设施中实施一样。如今,大多数设计者使新技术不断发展。他们明白在网络不断发展的同时,关键仍是技术对业务应用和业务流程的影响。网络战略的最大好处在于网络能转变传统企业经营模式。

关键词：企业网络 ATM 企业管理局域网

氢氯噻嗪和阿替洛尔的降压作用及对代谢的影响

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中华高血压杂志 2012年第6期20卷 598-598页

作者： steven M. smith Yan Gong stephen T. Turner Rhonda M. cooper-DeHoff Amber L. Beitelshees Arlene B. Chapman eric Boerwinkle Kent Bailey Julie A. Johnson John G. Gums 罗冬梅叶鹏

除影响血压水平外，噻嗪类利尿剂和β受体阻滞剂还会造成不良的代谢作用（adversemetaboliceffects，AME），这两种影响是否由相同的机制造成还不明确。

关键词：代谢作用降压作用阿替洛尔氢氯噻嗪 β受体阻滞剂噻嗪类利尿剂血压水平

Nat Genet:单基因突变导致过敏性皮炎的发生

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现代生物医学进展 2017年第27期17卷 I0004-I0004页

作者： Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D stone, Joshua D Milner Jeffrey R stinson, Elisa Ruffo, Batsukh Dorjbal, swadhinya Arjunaraja, Kelsey Voss, Andrew L snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo salomé Glauzy, Natsuko Yamakawa, eric Meffre Jennifer stoddard, Julie Niemela, sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A cooper Neil Romberg Laboratory of Allergic Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda Maryland USA Department of Pharmacology and Molecular Therapeutics Uniformed Services University of the Health Sciences Bethesda Maryland USA Immunodeficiency Diagnosis and Treatment Program Department of Pediatrics National Jewish Health Denver Colorado USA Department of Translational Medicine University of Piemonte Orientale Novara Italy Department of Immunobiology Yale University School of Medicine New Haven Connecticut USA Immunology service Department of Laboratory Medicine NIH Clinical Center National Institutes of Health Bethesda Maryland USA Human Immunological Disease section National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda Maryland USA Merck Research Laboratories Merck and Co. Inc. Boston Massachusetts USA Clinical Research Directorate/Clinical Monitoring Research Program Leidos Biomedical Research Inc. NCI Campus at Frederick Frederick Maryland USA servicio de Immunología y Reumatología Hospital Nacional de Pediatría Prof. Dr. Juan P. Garrahan Buenos Aires Argentina Division of Dermatology Department of Medicine Washington University School of Medicine St. Louis Missouri USA Department of Pediatrics Division of Rheumatology and Department of Pathology and Immunology Washington University School of Medicine St. Louis Missouri USA Department of Pediatrics Children’s Hospital of Philadelphia Philadelphia Pennsylvania USA.

最近，研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变：CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析，发现了这一导致疾病产生的基因、

关键词：过敏性皮炎基因突变 Nat 神经性皮炎血缘关系研究所传染病 NIH