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Optical and electrical nano eco-sensors using alternative deposition of charged layer

Frontiers of Materials Science 2011年第1期5卷 40-49页

作者： Syed Rahin AHMED Seong Cheol HONG jaebeom lee Department of Nanomedical Engineering College of Nanoscience and Nanoengineering Pusan National University Miryang 627-709 Korea

This review focuses on layer by layer （LBL） assembly-based nano ecological sensor （hereafter, eco-sensor） for pesticide detection, which is one of the most versatile methods. The effects of pesticides on human health and on the environment （air, water, soil, plants, and animals） are of great concern due to their increasing use. We highlight two of the most popular detecting methods, i.e., fluorescence and electrochemical detection of pesticides on an LBL assembly. Fluorescence materials are of great interest among researchers for their sensitivity and reliable detection, and electrochemical processes allow us to investigate synergistic interactions among film components through charge transfer mechanisms in LBL film at the molecular level. Then, we noted some prospective directions for development of different types of sensing systems.

关键词： pesticides fluorescence electrochemistry layer by layer (LBL)

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Mucoadhesive and antifouling Janus polysaccharide film for prevention of colorectal cancer recurrence post-surgery

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BMEMat(BioMedical Engineering Materials) 2024年第2期2卷 134-144页

作者： jaebeom lee Hee Seung Seo Chun Gwon Park Mikyung Shin Department of Intelligent Precision Healthcare Convergence Sungkyunkwan University(SKKU)SuwonRepublic of Korea Center for Neuroscience Imaging Research Institute for Basic Science(IBS)SuwonRepublic of Korea Department of Biomedical Engineering Sungkyunkwan University(SKKU)SuwonRepublic of Korea Biomaterials Research Center Korea Institute of Science and TechnologySeoulRepublic of Korea Biomedical Institute for Convergence Sungkyunkwan University(SKKU)SuwonRepublic of Korea

Colorectal cancer is one of the most common cancers,and current treatment options include surgery,chemotherapy,and radiation *** patients undergo surgery,which often requires extensive resection of the colon to prevent recurrence and metastasis of residual malignant tumor cells,leading to postoperative pain and discomfort in daily *** versatile therapeutic patches have been developed to induce tumor apoptosis,achieving both great adhesiveness on the mucus layers of the colon tissue and anti-cell/tissue adhesion to other surrounding organs remains a ***,we report a Janus polysaccharide film comprising two polymers:mussel-inspired catechol-conjugated chitosan(Chi-C)with muco-adhesiveness,and alginate(Alg)with anti-adhesion *** Chi-C and Alg polymers form a stably entangled bilayer film via electrostatic *** Janus film shows a strong tissue adhesive strength of~10 kPa for the Chi-C layer and weak strength of~1 kPa for the Alg ***,the Janus film encapsulating an anti-cancer drug exhibits a directional release profile to the tumor site,which is effective for triggering tumor death in in vivo colorectal tumor resection ***,such anti-cancer material strategies using bilayered structures are promising for advanced tumor therapy.

关键词： antifouling colon cancer mucoadhesive polysaccharide film

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Advances in All-Solid-State Lithium-Sulfur Batteries for Commercialization

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Nano-Micro Letters 2024年第9期16卷 209-246页

作者： Birhanu Bayissa Gicha Lemma Teshome Tufa Njemuwa Nwaji Xiaojun Hu jaebeom lee Research Institute of Materials Chemistry Chungnam National UniversityDaejeon 34134Republic of Korea Institute of Fundamental Technological Research Polish Academy of Sciences02‑106 WarsawPoland School of Life Sciences Shanghai University200444 ShanghaiPeople’s Republic of China Department of Chemistry Chungnam National UniversityDaejeon 34134Republic of Korea

Solid-state batteries are commonly acknowledged as the forthcoming evolution in energy storage *** development progress for these rechargeable batteries has notably accelerated their trajectory toward achieving commercial *** particular,all-solid-state lithium-sulfur batteries(ASSLSBs)that rely on lithium-sulfur reversible redox processes exhibit immense potential as an energy storage system,surpassing conventional lithium-ion *** can be attributed predominantly to their exceptional energy density,extended operational lifespan,and heightened safety *** these advantages,the adoption of ASSLSBs in the commercial sector has been *** expedite research and development in this particular area,this article provides a thorough review of the current state of *** delve into an in-depth analysis of the rationale behind transitioning to ASSLSBs,explore the fundamental scientific principles involved,and provide a comprehensive evaluation of the main challenges faced by *** suggest that future research in this field should prioritize plummeting the presence of inactive substances,adopting electrodes with optimum performance,minimizing interfacial resistance,and designing a scalable fabrication approach to facilitate the commercialization of ASSLSBs.

关键词： All-solid-state lithium-sulfur batteries Commercialization Enhancement strategies Solid-state electrolytes Sulfurbased cathodes

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RGD peptide and graphene oxide co-functionalized PLGA nanofiber scaffolds for vascular tissue engineering

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Regenerative Biomaterials 2017年第3期4卷 159-166页

作者： Yong Cheol Shin Jeonghyo Kim Sung Eun Kim Su-Jin Song SuckWon Hong Jin-Woo Oh jaebeom lee Jong-Chul Park Suong-Hyu Hyon Dong-Wook Han Department of Cogno-Mechatronics Engineering Department of Optics and Mechatronics Engineering Department of Nanoenergy Engineering College of Nanoscience and NanotechnologyPusan National UniversityBusan 46241Korea Cellbiocontrol Laboratory Department of Medical EngineeringYonsei University College of MedicineSeoul 03722Korea and 5Center for Fiber and Textile Science Kyoto Institute of TechnologyMatsugasakiKyoto 606-8585Japan

In recent years,much research has been suggested and examined for the development of tissue engineering scaffolds to promote cellular *** our study,RGD peptide and graphene oxide(GO)co-functionalized poly(lactide-co-glycolide,PLGA)(RGD-GO-PLGA)nanofiber mats were fabricated via electrospinning,and their physicochemical and thermal properties were characterized to explore their potential as biofunctional scaffolds for vascular tissue *** electron microscopy images revealed that the RGD-GO-PLGA nanofiber mats were readily fabricated and composed of randomoriented electrospun nanofibers with average diameter of *** successful co-functionalization of RGD peptide and GO into the PLGA nanofibers was confirmed by Fourier-transform infrared spectroscopic ***,the surface hydrophilicity of the nanofiber mats was markedly increased by co-functionalizing with RGD peptide and *** was found that the mats were thermally stable under the cell culture ***,the initial attachment and proliferation of primarily cultured vascular smoothmuscle cells(VSMCs)on the RGD-GO-PLGA nanofibermats were *** was revealed that the RGD-GO-PLGA nanofibermats can effectively promote the growth of *** conclusion,our findings suggest that the RGD-GO-PLGA nanofiber mats can be promising candidates for tissue engineering scaffolds effective for the regeneration of vascular smooth muscle.

关键词： RGD peptide graphene oxide poly(lactic-co-glycolic acid) biofunctional scaffold vascular smooth muscle cell

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Development of large acceptance multi-purpose spectrometer in Korea for symmetry energy

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Nuclear Science and Techniques 2018年第12期29卷 6-14页

作者： Byungsik Hong Jung Keun Ahn Gyeonghwan Bak Jamin Jo Minho Kim Eun Joo Kim Young Jin Kim Young Jun Kim Minjung Kweon Hanseul lee Hyo Sang lee Jong-Won lee Jung Woo lee Kyong Sei lee Byul Moon Dong Ho Moon Benard Mulilo jaebeom Park Min Sang Ryu Hyunha Shim LAMPS Collaboration Department of Physics Korea University Seoul 02841Republic of Korea Department of Physics Chonnam National UniversityGwangju 61186 Republic of Korea Division of Science Education Chonbuk National UniversityJeonju 54896 Republic of Korea Rare Isotope Science Project Institute for Basic ScienceDaejeon 34047 Republic of Korea Department of Physics Inha University Incheon 22212Republic of Korea

The Rare Isotope Accelerator complex for ONline experiments(RAON) is a new radioactive ion beam accelerator facility under construction in Korea. The large acceptance multi-purpose spectrometer(LAMPS) is one of the experimental devices for nuclear physics at RAON. It focuses on the nuclear symmetry energy at supra-saturation densities. The LAMPS Collaboration has developed and constructed various detector elements, including a time projection chamber(TPC) and a forward neutron detector array. From the positron beam test, the drift velocity of the secondary electrons in the TPC is 5:3±0:2 cm/ls with P10 gas mixture, and the position resolution for pads with dimensions of 4×15 mm^2 is in the range of$ 0.6–0.8 mm, depending on the beam position. From the neutron beam test, the energy resolution of the prototype neutron detector module is determined to be 3.4%, and theposition resolution is estimated to be better than 5.28 *** present, the construction of the LAMPS neutron detector system is in progress.

关键词：分光计精力用途朝鲜对称开发核物理学合作发展

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