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Journal of Biosciences and Medicines 2023年第10期11卷 35-45页

作者： Yapo Fulgence Allo Viviane Jocelyne Zannou-Tchoko Kouamé Hermann Yéboué Brou André Konan jacques yao datté Biology and Health Laboratory UFR Biosciences Félix Houphou&eumlt-Boigny University Abidjan C&ocircte d’Ivoire

Purpose: This study was conducted in order to evaluate the antidiabetic effects of the aqueous extract of Lippia multiflora supplemented with magnesium on some biochemical markers of the kidneys and liver in type 2 diabetic rats. Method: 7 groups of 4 STZ-diabetic rats received separately orally Glucophage® (Glu 10 mg/kg), the plant extract (LiMAE 200 - 600 mg/kg) and the plant extract supplemented with magnesium (LiMAE-Mg 200 - 600 mg/kg). After a daily treatment of 21 days, serum biochemical parameters were assayed in 16 hr-fasted rats. Results: Diabetes caused a significant (p Conclusion: The addition of magnesium to the extract of Lippia multiflora caused a greater reduction in the levels of urea, creatinine, ALT and AST increased in STZ-diabetic rats. Magnesium would therefore enhance the nephroprotective and hepatoprotective effects of Lippia multiflora in diabetic rats.

关键词： Lippia multiflora Diabetes Streptozotocin Nephroprotective Hepatoprotective

Comparative Study on Microstructure and Mechanical Properties of Coarse-grained WC-based Cemented Carbides Sintered with Ultrafine WC or (W+C) as Additives

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Journal of Wuhan University of Technology(Materials Science) 2024年第2期39卷 399-409页

作者：于淞百闵凡路 LI De NOUDEM Guillaume jacques ZHANG Hailong MA Jichang ZHAO Kui yao Zhanhu 张建峰 College of Mechanics and Materials Hohai UniversityNanjing 210098China Key Laboratory of Geomechanics and Embankment Engineering Hohai UniversityMinistry of EducationNanjing 210098China CRISMAT-ENSICAEN(UMR-CNRS 6508) Universitéde Caen-Basse-NormandieF-14050 CaenFrance Shaanxi Aeronautic Carbide Tool Co.Ltd. Hanzhong 724200China CCCC Tunnel Engineering Co.Ltd. Beijing 100102China

The effects of ultrafine WC(WC_(UF),0.5μm) or W(1μm) and C(0.3μm)(W+C)_(UF) additives on the densification,microstructure and mechanical properties of coarse-grained cemented carbides were compared ***,the cemented carbides with WC_(UF)/(W+C)_(UF) additives are almost fully densification to be higher than 99%,and the average grain size is kept above 2.8μ*** WC_(UF) additive assists grains to(truncated)trigonal prism shape by two dimensional(2D) growth,whereas the(W+C)_(UF) additive assists grains to rounded shape by three dimensional(3D) growth,lowers WC contiguity and increases face-centered-cubic *** hardness and bending strength of(75WC_(C)-15WC_(UF))-10Co are 86.6 HRA and 2 272 MPa,respectively,both higher than those of(75WC_(C)-15(W+C)_(UF))-10Co,which could be ascribed to the enhanced densification and unblemished ***,the fracture toughness of the(75WC_(C)-15(W+C)_(UF))-10Co is 23.5 MPa·m^(1/2),higher than that of the(75WC_(C)-15WC_(UF))-10Co due to the uniform WC-Co structure and flexible binder phase.

关键词： coarse-grained WC-based cemented carbide ultrafine WC ultrafine(W+C) microstructure mechanical properties

Hydrogeochemical Characterization of Groundwater from Fissured Aquifers in the Angovia Mine Operating Permit Area (Central-West Côte d’Ivoire)

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Journal of Water Resource and Protection 2024年第1期16卷 83-101页

作者： Kouadio Michel yao Tanina Drissa Soro Tanoh Jean jacques Koua Akaie Jean Fabrice Tchakray yao Emile Desmond Konan Brou Dibi Laboratory of Sciences and Technologies of Environment University Jean Lorougnon Guede Daloa C&ocircte d’Ivoire

The main objective of this study is to determine the hydrogeochemical specificities of the groundwater of the Angovia mine operating permit, located in the yaouré mountains in the center-west of Côte d’Ivoire. To do so, descriptive and multivariate statistical analysis methods with the SOM (Self Organizing Maps) algorithm were applied to the physicochemical parameters of 17 boreholes using the calcite (ISC) and dolomite (ISD) saturation indices. The results obtained have shown that the groundwater in the Angovia mine operating permit area has an average temperature of 27.52°C (long rainy season) and 27.87°C (long dry season) and has an average pH of 7.09 ± 0.35 during the main rainy season and 7.32 ± 0.35 during the main dry season. They are mineralized with an average electrical conductivity of 505.98 ± 302.85 μS/cm during the long rainy season and with 450.33 ± 233.74 μS/cm as average during the long dry season. The main phenomena at the origin of groundwater mineralization are water residence time, oxidation-reduction and surface inflow. The study of the relative age of the water shows that the groundwater in the Angovia mine operating permit area is mainly undersaturated with respect to calcite and dolomite. They are therefore very old in the aquifer with a slow circulation speed during the long rainy season and the long dry season.

关键词： Hydrogeochemistry Mineralization Fissure Aquifers Operating Permits The Angovia Mine

Epidemiological, Clinical Progress Aspects of Congenital Heart Disease with Neonatal Revelation at the Mother-Child Hospital of Bingerville (HME) Concerning 98 Cases from January 2021 to December 2022 (Côte d’Ivoire)

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Open Journal of Pediatrics 2024年第1期14卷 89-100页

作者： Adja Evelyne Akaffou-Gbery Richard Azagoh-Kouadio Anne-Lise Laetitia Mobio Jean-jacques yao Atteby Serenah Marie Janice N’vrah Anoh Kouassi Raoul yao Department of Paediatrics and Neonatology H&#244pital Mère-Enfant de Bingerville (HME) Bingerville C&#244te d’Ivoire Department of Medical Pediatrics and Specialties CHU de Angré Abidjan C&#244te d’Ivoire

Introduction The distribution of congenital heart disease (CHD) in sub-Saharan Africa is highly imprecise and varies from one region to another due to the inequality of diagnostic facilities. The aim of this study was to determine the in-hospital prevalence of congenital heart disease in children at the Mother-Child hospital of Bingerville (HME) by specifying the diagnostic, therapeutic and evolutionary aspects. Materials and methods We conducted a retrospective, descriptive, cross-sectional study at HME of Bingerville from January 2021 to December 2022. All newborns with congenital heart disease confirmed by echocardiography were included in the study. Results Of 656 admissions to the neonatology department over the study period, congenital heart disease accounted for 14.9% (98/656) of cases. In our series, 76.7% were diagnosed before the 1st week of life, with a mean chronological age of 5.18 days and extremes of 0 and 46 days. There were as many male patients (50%) as female (50%), i.e. a sex ratio of 1. These newborns were premature in 60.2% of cases, with a mean and median gestational age of 34 weeks’ amenorrhea. Most were left-right shunts (90.8%). Persistent ductus arteriosus (PDA) (48.9%) predominated, followed by atrial septal defect (38.7%), ventricular septal defect (13.3%), common trunk artery (CTA) (3.1%) and open septal pulmonary atresia (OSPA) (1%) as the primary cyanogenic heart disease. Pulmonary arterial hypertension (PAH) (50%) was primary in 38.8% and secondary (61.2%). The mortality rate was 30.6%, and all CTA patients died (100%), with a significant statistical relationship (p = 0.027). Progression under treatment was marked by clinical stabilization (68/98) in 69.4% of cases. Conclusion: Congenital heart disease is relatively common at the Bingerville HME. Access to echocardiography should be facilitated in neonatology departments for rapid diagnosis and optimal management of congenital heart disease in newborns.

关键词： Newborn Congenital Heart Disease Côte d’Ivoire

Drag reduction via turbulent boundary layer flow control

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Science China(Technological Sciences) 2017年第9期60卷 1281-1290页

作者： ABBAS Adel BUGEDA Gabriel FERRER Esteban FU Song PERIAUX jacques PONS-PRATS Jordi VALERO Eusebio ZHENG yao School of Aeronautics Escuela Tecnica Superior de lngenierla Aeronautica y del Espacio de la Universidad Politecnica de Madrid (ETS1.4E-UPM) Universidad Politecnica de Madrid Pza. Cardenal Cisneros 3 Madrid E-28040 Spain International Center for Numerical Methods in Engineering (CIMNE) Gran Capita s/n Campus Nord UPC Barcelona 08034 Spain Civil and Environmental Department Universitat Politecnica de Catalunya. BarcelonaTech Gran Capita s/n Campus Nord UPC Barcelona 08034 Spain Centre for Computational Simulation-UPM Scientific and Technological Park (Campus Montegancedo) 28223 Pozuelo de Alarcon Spain School of Aerospace Engineering Tsinghua University Beijing 100084 China School of Aeronautics andAstronautics Zhejiang University Hangzhou 310027 China

Turbulent boundary layer control(TBLC) for skin-friction drag reduction is a relatively new technology made possible through the advances in computational-simulation capabilities,which have improved the understanding of the flow structures of *** in micro-electronic technology have enabled the fabrication of active device systems able to manipulating these *** combination of simulation,understanding and micro-actuation technologies offers new opportunities to significantly decrease drag,and by doing so,to increase fuel efficiency of future *** literature review that follows shows that the application of active control turbulent skin-friction drag reduction is considered of prime importance by industry,even though it is still at a low technology readiness level(TRL).This review presents the state of the art of different technologies oriented to the active and passive control for turbulent skin-friction drag reduction and contributes to the improvement of these technologies.

关键词： turbulent boundary layer flow control drag reduction skin-friction drag reduction

团头鲂PGC1α分子特征及其对营养限制、高糖饲料和葡萄糖负荷的响应

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水产学报 2021年第10期45卷 1657-1666页

作者：丁志荣李向飞刘文斌谢帝芝徐超 Jean-jacques yao Adjoumani 华南农业大学海洋学院南京农业大学动物科技学院江苏省水产动物营养重点实验室

为探究过氧化物酶体增殖活化受体γ辅激活因子1α(peroxisome proliferator activated receptorγcoactivator 1α,PGC1α)基因在团头鲂糖代谢中的作用,实验从团头鲂肝脏中克隆获得了PGC1α基因的片段序列,并对其开展了生物信息学分析;... 详细信息

为探究过氧化物酶体增殖活化受体γ辅激活因子1α(peroxisome proliferator activated receptorγcoactivator 1α,PGC1α)基因在团头鲂糖代谢中的作用,实验从团头鲂肝脏中克隆获得了PGC1α基因的片段序列,并对其开展了生物信息学分析;同时研究了饥饿、高糖(糖水平:45%)饲料及葡萄糖负荷对团头鲂脑和肝脏PGC1α表达的影响。结果显示,获得的团头鲂PGC1α基因c DNA片段长为2 566 bp,其中包含1 404 bp的开放阅读框并编码467个氨基酸,与草鱼的同源性为96.79%;与正常投喂组相比,饥饿10 d组鱼脑和肝脏中PGC1α的mRNA水平显著升高,饥饿再投喂1 h后恢复至对照组的表达水平。饲喂高糖饲料(12周)后,与对照组相比,鱼脑和肝脏中PGC1α的mRNA水平显著降低。此外,葡萄糖负荷后,脑和肝脏中PGC1α的mRNA水平在2 h内显著降低至最小值,随后逐渐升高至基础水平。研究表明,PGC1α在团头鲂糖代谢过程中可能发挥重要作用。

关键词：团头鲂过氧化物酶体增殖活化受体γ辅激活因子1α 糖代谢基因克隆基因表达

团头鲂PGC1β基因克隆及高糖胁迫、葡萄糖和胰岛素负荷对其mRNA表达的影响

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中国水产科学 2021年第8期28卷 959-967页

作者：徐超刘文斌谢帝芝丁志荣 Jean-jacques yao Adjoumani 石泉李向飞华南农业大学海洋学院南京农业大学动物科技学院江苏省水产动物营养重点实验室

为探讨过氧化物酶体增殖活化受体γ辅激活因子1β(peroxisome proliferator activated receptorγcoactivator 1β,PGC1β)基因在鱼类糖代谢中的作用,本研究采用RACE方法获得了团头鲂PGC1β的cDNA片段序列,利用生物信息学技术对该基因... 详细信息

为探讨过氧化物酶体增殖活化受体γ辅激活因子1β(peroxisome proliferator activated receptorγcoactivator 1β,PGC1β)基因在鱼类糖代谢中的作用,本研究采用RACE方法获得了团头鲂PGC1β的cDNA片段序列,利用生物信息学技术对该基因及其所编码蛋白的结构特征进行了分析;采用实时定量PCR技术,检测了高糖(45%)饲喂、葡萄糖及胰岛素负荷对团头鲂肝脏和肌肉中该基因表达的影响。结果显示,团头鲂PGC1βcDNA片段长为1759 bp,其中开放阅读框为1719bp,编码573个氨基酸;同源性分析结果显示,团头鲂PGC1β与其他鲤科鱼类的PGC1β高度同源(氨基酸相似度78%以上),并与草鱼PGC1β的进化关系最近;高糖组鱼肝脏和肌肉中PGC1β的表达量高于对照组,但无显著差异;此外,葡萄糖及胰岛素负荷后,肝脏中PGC1β基因的表达量在2h内显著降低至最小值,随后逐渐升高至基础水平。以上结果提示, PGC1β可能在调节鱼类糖代谢中发挥重要作用。

关键词：团头鲂过氧化物酶体增殖活化受体γ辅激活因子1β 基因克隆糖代谢基因表达

Preparation and properties of Ni-coated WC powder and highly impact resistant and corrosion resistant WC-Ni cemented carbides

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Transactions of Nonferrous Metals Society of China 2022年第6期32卷 1935-1947页

作者： Fan-lu MIN Song-bai YU Sheng WANG Zhan-hu yao jacques Guillaume NOUDEM Si-jin LIU Jian-feng ZHANG Key Laboratory of Geomechanics and Embankment Engineering Ministry of EducationHohai UniversityNanjing 210098China College of Civil and Transportation Engineering Hohai UniversityNanjing 210098China College of Mechanics and Materials Hohai UniversityNanjing 210098China CCCC Tunnel Engineering Company Limited Beijing 100102China CRISMAT-ENSICAEN(UMR-CNRS 6508) Universitéde Caen-Basse-NormandieCaenF-14050France China Railway 14th Bureau Group Co. Ltd.Jinan 250101China

WC powders were uniformly coated by Ni nanoparticles through a combined chemical co-precipitation and subsequent high temperature hydrogen reduction strategy(abbreviated as CM-WCN),and then were consolidated by vacuum sintering at 1450°C for 1 h to obtain WC−Ni cemented *** microstructure and properties of the as-consolidated CM-WCN were *** average grain size of WC in the consolidated CM-WCN was calculated to be in the range of 3.0−3.8μm and only few pores were observed.A relative density of 99.6%,hardness of HRA 86.5 and bending strength of 1860 MPa were obtained for the CM-WCN−10wt.%Ni,and the highest impact toughness of 6.17 J/cm^(2 )was obtained for the CM-WCN−12wt.%Ni,surpassing those of the hand mixed WC−Ni(HM-WCN)cemented carbides examined in this study and the other similar materials in the ***-WCN cemented carbides possess excellent mechanical properties,due to their highly uniform structure and low porosity that could be ascribed to the intergranular-dominated fracture mode accompanied by a large number of plastic deformation tears of the bonding *** addition,the corrosion resistance of CM-WCN was superior to that of HM-WCN at the Ni content of 6−12 wt.%.

关键词： WC−Ni cemented carbides chemical co-precipitation method high temperature hydrogen reduction strategy Ni content microstructure impact toughness corrosion resistance

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耦合摆特性模拟及振动耦合现象演示

大学物理 2012年第4期31卷 28-32页

作者：姚盛伟徐平 jacques TABUTEAU 北京航空航天大学物理科学与核能工程学院北京100191 北京航空航天大学中法工程师学院北京100191

分析了机械耦合摆的振动特性及耦合过程,提出了利用互感耦合电路模拟耦合摆的方法;设计并制作了—种互感耦合装置,模拟机械耦合摆的振动耦合和能量转换过程;通过与机械耦合的比对演示,将两种耦合的特性分析归结为相同的数学问题,在演示... 详细信息

分析了机械耦合摆的振动特性及耦合过程,提出了利用互感耦合电路模拟耦合摆的方法;设计并制作了—种互感耦合装置,模拟机械耦合摆的振动耦合和能量转换过程;通过与机械耦合的比对演示,将两种耦合的特性分析归结为相同的数学问题,在演示物理现象的同时,培养学生数学建模能力和对系统的综合分析能力.

关键词：耦合摆互感耦合数学建模

Clinical and Epidemiological Features and Management of Neonatal Hypoglycemia at the University Teaching Hospital of Treichville (Abidjan-Côte d’Ivoire)

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Open Journal of Pediatrics 2017年第4期7卷 320-330页

作者： Gneneyeri Joseph Ouattara Lassina Cissé Gervais Koffi Jean-jacques Atteby yao Jacob Enoh Corinne Sei Soumahoro Oulai Department of Paediatrics University Teaching Hospital of Treichville Abidjan Cote d’Ivoire Unit of Biochemistry Central Laboratory University Teaching Hospital of Treichville Abidjan Cote d’Ivoire

The purpose of this study is to determine the prevalence, the characteristics of hypoglycaemia in the newborn admitted to emergency departments of teaching Hospital of Treichville, Abidjan and to evaluate the relevance of capillary blood glucose in this diagnosis. Patients and Methods: This prospective cross-sectional study was held from 01 February to 25 June 2017 in the Pediatric Emergency Department. It involved 201 newborns under 24 hours of age who consulted in pediatric emergency for any reason. Data were collected from parent direct interviews, analysis of the follow-up record, physical examination of the newborn, results of glucose level in the capillary blood at heel and in venous blood. On dry tube and gray tube (containing sodium fluoride and potassium oxalate), the blood glucose on the latter tube constituting the reference blood glucose, with neonatal hypoglycaemia defined by a venous blood glucose less than or equal to 2.5 mmol/l (0.45 g/l). The statistical tests used were the frequency comparison, the Chi Square, the Fisher Test with a significance threshold p 0.05 or the Odds-ratio with a confidence interval of 95% and a significance threshold of 5%, but also with the correlation coefficient. Results: Newborns of less than 3 hours of life (70.6%) were the most represented with a male predominance (sex ratio = 2.9). The reasons for consultation were dominated by neurological disorders (36.5%), prematurity (31.8%), and fever (22.2%). The average time to complete the blood glucose test was less than one hour after the sampling in 6.5% of the cases. The mean blood glucose was 0.59 g/l (3.28 mmol/l) with extremes ranging from 0.15 to 1.8 g/l (0.83 mmol/l to 10 mmol/l). The prevalence of hypoglycemia by the instantaneous glycemic method was 15.9%. On tube containing sodium fluoride and potassium oxalate, it was 20.4%, while the prevalence of red blood cell hypoglycemia was 38.1%. A good correlation was found between capillary glycemia and gray tube with r

关键词： Hypoglycaemia Newborn Prevalence Emergency