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Immunomodulatory extracellular matrix hydrogel induces tissue regeneration in a model of partial glossectomy

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Bioactive Materials 2024年第8期38卷 528-539页

作者： Emma I.Zelus Aaron Panduro Isha Deshmukh jacqueline Grime Marianna Alperin Andrew M.Vahabzadeh-Hagh Karen L.Christman Shu Chien-Gene Lay Department of Bioengineering UC San Diego9500 Gilman Dr.MC 0412La JollaCA92093-0412USA Department of Obstetrics Gynecologyand Reproductive SciencesDivision of Female Pelvic Medicine and Reconstructive SurgeryUC San Diego School of Medicine9300 Campus PointMC 7433La JollaCA92037-7433USA Department of Otolaryngology-Head&Neck Surgery UC San Diego School of Medicine9300 Campus PointMC 7400La JollaCA92037-7400USA Sanford Consortium for Regenerative Medicine 2880 Torrey Pines Scenic DriveLa JollaCA92037USA Sanford Stem Cell Institute 2880 Torrey Pines Scenic DriveLa JollaCA92037USA

While oropharyngeal cancer treatment regimens,including surgical resection,irradiation,and chemotherapy,are effective at removing tumors,they lead to muscle atrophy,denervation,and fibrosis,contributing to the pathogenesis of oropharyngeal dysphagia-difficulty *** standard of care of rehabilitative tongue strengthening and swallowing exercises is ***,we evaluate an alternative approach utilizing an acellular and injectable biomaterial to preserve muscle content and reduce fibrosis of the tongue after *** muscle extracellular matrix(SKM)hydrogel is fabricated from decellularized porcine skeletal muscle tissue.A partial glossectomy injury in the rat is used to induce tongue fibrosis,and SKM hydrogels along with saline controls are injected into the site of scarring two weeks after *** are harvested at 3 and 7 days post-injection for gene expression and immunohistochemical analyses,and at 4 weeks post-injection to evaluate histomorphological *** hydrogel reduces scar formation and improves muscle regeneration at the site of injury compared to *** additionally modulates the immune response towards an anti-inflammatory *** study demonstrates the immunomodulatory and tissue-regenerative capacity of an acellular and minimally invasive ECM hydrogel in a rodent model of tongue injury.

关键词： Extracellular matrix Biomaterial Hydrogel Skeletal muscle regeneration Partial glossectomy Dysphagia Immunomodulation

Numerical Simulation of Fluid Flow Inside a Molten Liquid Metal Droplet Located in an Electromagnetic Induction Generated by Two Different Inducting Currents

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Journal of Iron and Steel Research International 2012年第S1期19卷 127-130页

作者： Alimata DIARRA Annie GAGNOUD jacqueline ETAY Andreas STEIN Rainer WUNDERLICH SIMaP-EPM CNRS-INPG-UJF Phelma-Campus BP75 38402 St Martin d'Heres cedexFrance EADS Astrium Department TEB 2288039 FriedrichshafenGermany Institute of Micro and Nanomaterials Ulm University Albert-Einstein-Allee 4789081 UlmGermany

Electromagnetic levitation of electrically conductive droplets by alternating magnetic fields is Sa technique used to measure the physical properties of liquid metallic alloys such as surface tension,viscosity,heat *** can be conducted in microgravity,to reduce electromagnetic stirring and shaping of the *** inductor of the EML is composed of a single inductor which two types of voltage are *** type of electrical installation generates a field to center the metallic droplet and another field to heat and excite *** use a commercial code join to a homemade code to compute flows generated by inducting voltages recorded in the sounding rocket TEXUS-EML-2(Feb2008).In this flight,two samples(Cu75Co25 at%and A168,5Ni31,5 at%)of 8 mm diameter have been processed.

关键词： electromagnetic levitation superposed inducting currents microgravity electromagnetic stirring

A portrait of the artist as a young man

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A portrait of the artist as a young man

作者： James Joyce introduction and notes by Dr. jacqueline Belanger.

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新生儿戒断综合征管理研究进展

中国护理管理 2020年第11期20卷 1666-1670页

作者： jacqueline McGrath 褚梁梁得克萨斯大学圣安东尼奧健康科学中心护理学院美国78229 山东第一医科大学第一附属医院产科

在出生前接触阿片类药物的新生儿通常会出现一系列药物戒断症状,称为新生儿戒断综合征(Neonatal Abstinence Syndrome,NAS)。近年来,NAS发病率大幅上升,以非药物干预和病房管理为重点的新型护理模式在治疗方面越来越突出,可明显缩短其... 详细信息

在出生前接触阿片类药物的新生儿通常会出现一系列药物戒断症状,称为新生儿戒断综合征(Neonatal Abstinence Syndrome,NAS)。近年来,NAS发病率大幅上升,以非药物干预和病房管理为重点的新型护理模式在治疗方面越来越突出,可明显缩短其住院时间和减少药物使用量。本篇综述将重点探讨NAS的管理,回顾其发展历史、评分工具和管理方法演变,总结与归纳关于NAS相关护理工作的建议。

关键词：新生儿戒断综合征新生儿撤药综合征护理管理

Information in action a guide to technical communication M. Jimmie Killingsworth, jacqueline S. Palmer 2nd ed.

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Information in action a guide to technical communication M. ...

Direct observation of photonic Landau levels and helical edge states in strained honeycomb lattices

1999年

作者： M. Jimmie Killingsworth jacqueline S. Palmer

来源：畅想之星图书光盘版（南... 评论

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Light(Science & Applications) 2020年第1期9卷 627-636页

作者： Omar Jamadi Elena Rozas Grazia Salerno Marijana Milicevic Tomoki Ozawa Isabelle Sagnes Aristide Lemaitre Luc Le Gratiet Abdelmounaim Harouri Iacopo Carusotto jacqueline Bloch Alberto Amo Universite de Lille CNRSUMR 8523—PhLAM—Physique des Lasers Atomes et Molecules59000 LilleFrance Depto.de Fisica de Materiales e Instituto Nicolas Cabrera Universidad Autonoma de Madrid(UAM)28049 MadridSpain Center for Nonlinear Phenomena and Complex Systems Universite Libre de BruxellesCP 231Campus PlaineB-1050 BrusselsBelgium Universite Paris-Saclay CNRSCentre de Nanosciences et de Nanotechnologies91120 PalaiseauFrance Interdisciplinary Theoretical and Mathematical Sciences Program(iTHEMS) RIKENWakoSaitama 351-0198Japan INO-CNR BEC Center and Dipartimento di Fisica Universita di Trento38123 PovoItaly

We report the realization of a synthetic magnetic field for photons and polaritons in a honeycomb lattice of coupled semiconductor micropillars.A strong synthetic field is induced in both the s and p orbital bands by engineering a uniaxial hopping gradient in the lattice,giving rise to the formation of Landau levels at the Dirac *** provide direct evidence of the sublattice symmetry breaking of the lowest-order Landau level wavefunction,a distinctive feature of synthetic magnetic *** realization implements helical edge states in the gap between n=0 and n=±1 Landau levels,experimentally demonstrating a novel way of engineering propagating edge states in photonic *** light of recent advances in the enhancement of polariton–polariton nonlinearities,the Landau levels reported here are promising for the study of the interplay between pseudomagnetism and interactions in a photonic system.

关键词： Landau helical realization

Evaluation of ambient mass spectrometry tools for assessing inherent postharvest pepper quality

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Horticulture Research 2021年第1期8卷 2252-2259页

作者： Tyler J.Mason Harmonie M.Bettenhausen jacqueline M.Chaparro Mark E.Uchanski Jessica E.Prenni Department of Horticulture and Landscape Architecture Colorado State UniversityFort CollinsCO 80524USA

Horticulturists are interested in evaluating how cultivar,environment,or production system inputs can affect postharvest *** mass spectrometry approaches enable analysis of minimally processed samples under ambient conditions and offer an attractive high-throughput alternative for assessing quality characteristics in plant ***,we evaluate direct analysis in real time(DART-MS)mass spectrometry and rapid evaporative ionization-mass spectrometry(REIMS)to assess quality characteristics in various pepper(Capsicum annuum L.)***-MS exhibited the ability to discriminate between pod colors and pungency based on chemical fingerprints,while REIMS could distinguish pepper market class(e.g.,bell,lunchbox,and popper).Furthermore,DART-MS analysis resulted in the putative detection of important bioactive compounds in human diet such as vitamin C,p-coumaric acid,and *** results of this study demonstrate the potential for these approaches as accessible and reliable tools for high throughput screening of pepper quality.

关键词： cultivar pepper ambient

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L'Arme secrète

法语学习 2001年第5期 11-12页

作者： Claude et jacqueline Held

Evidence that the Vinland Map Was Drawn Using an Iron Gall Ink: The Continuing Need for Further Research

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Advances in Chemical Engineering and Science 2012年第4期2卷 514-518页

作者： jacqueline S. Olin Great Falls USA

The Vinland Map is a map of the world that shows “the island of Vinland” in the northwest Atlantic Ocean. It is housed in the Beinecke Rare Book and Manuscript Library at Yale University. The Map has been purported to date from the Council of Basle, AD 1431-1449. The nature of the ink of the Map has not been identified. It has been suggested that it may be an iron gall ink, a carbon ink or an ink that contains anatase and gelatin and perhaps other unknown constituents. This paper will present evidence that supports the ink being an iron gall ink. It is intended that this evidence will encourage further research.

关键词： Iron Gall Ink UV Examination of Iron Gall Ink Iron Gall Ink Corrosion