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Topical application of adipose tissuederived mesenchy.al stem cells(ADMSCs)reduced cerebral edema in experimental traumatic brain injury.TBI)-a preliminary.study

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Chinese Neurosurgical Journal 2021年第2期7卷 131-136页

作者： Hui Ma Lian Xu Cui Ping Kuen lam Cindy.S.w.Tong Kin K.y.Lo George K.C.wong wai Sang Poon Division of Neurosurgery Chow Tai Fook-Cheng Yu Tung Surgical Stem Cell Research CenterDepartment of SurgeryThe Chinese University of Hong KongShatinHong KongSARChina Division of Neurosurgery Department of SurgeryFo Shan First People’s HospitalFoshanGuangdongChina

Background:Our previous studies showed that topical application of mesenchy.al stem cells(MSCs)improved functional recovery.in rat traumatic brain injury.TBI)model,and hy.oxic precondition further enhanced the therapeutic effects of *** was no previous study.on the attenuation of cerebral edema by.*** investigated whether topical application of normoxic and hy.oxic MSCs could reduce cerebral edema in an experimental TBI ***:Two million normoxic(N=24)and hy.oxic(N=24)MSCs were applied topically.to exposed the cerebral cortex in a controlled cortical impact(CCI)*** MSCs were fixed in position with fibrin *** treatment was given to control animals(TBI only.n=24).After surgery.four animals in each group were sacrificed daily.day.1 to day.6)for edema *** animals without TBI were used as reference(n=4).The expressions of GFAP,AQP4,and MMP9 were also investigated by.immunofluorescence staining and RT-PCR at day.***:The edema peaked within 3 day. after *** with the control,hy.oxic MSCs reduced brain water content significantly.py.oxic and normoxic MSCs downregulated the expression of MMP9 and normalized AQP4 distribution to astrocy.e end ***:Our preliminary.study.showed that topical application of hy.oxic MSCs suppressed both vasogenic and cy.otoxic edema formation.

关键词： Topical MSCs Cerebral edema TBI

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间隔基长度对侧链液晶聚炔相行为的影响

间隔基长度对侧链液晶聚炔相行为的影响

2013年全国高分子学术论文报告会

作者：余振强张哲林杰生朱才镇陈尔强 lam jacky.w.y. 唐本忠深圳大学化学与化工学院深圳市功能高分子重点实验室北京大学化学与分子工程学院香港科技大学化学系

＜正＞聚乙炔等具有刚性主链的侧链液晶高分子的相结构与相转变的研究对理解高分子液晶凝聚态结构具有重要意义。单取代侧链液晶聚炔的本体相结构研究表明,当主链为顺式构型时,分子形成刚性柱状结构,进而堆砌形成柱状液晶相;当主链为反... 详细信息

＜正＞聚乙炔等具有刚性主链的侧链液晶高分子的相结构与相转变的研究对理解高分子液晶凝聚态结构具有重要意义。单取代侧链液晶聚炔的本体相结构研究表明,当主链为顺式构型时,分子形成刚性柱状结构,进而堆砌形成柱状液晶相;当主链为反式构型时,较短的间隔基使刚性主链和侧链液晶基元之间耦合形成片状结构,可以堆砌形成分子间排列受挫的高级有序

关键词：聚炔联苯近晶相 X-射线衍射准长程有序

Artificial intelligence-driven radiomics study.in cancer:the role of feature engineering and modeling

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Military.Medical Research 2024年第1期11卷 115-147页

作者： y.an-Peng Zhang Xin-y.n Zhang y.-Ting Cheng Bing Li Xin-Zhi Teng Jiang Zhang Saikit lam Ta Zhou Zong-Rui Ma Jia-Bao Sheng Victor CwTam Shara wy.ee Hong Ge Jing Cai Department of Medical Informatics Nantong UniversityNantong 226001JiangsuChina Department of Health Technology.and Informatics the Hong Kong Polytechnic UniversityHong Kong 999077China The Hong Kong Poly.echnic University.Shenzhen Research Institute Shenzhen 518000GuangdongChina Department of Radiation Oncology the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer HospitalZhengzhou 450008China

Modern medicine is reliant on various medical imaging technologies for non-invasively.observing patients’***,the interpretation of medical images can be highly.subjective and dependent on the expertise of ***,some potentially.useful quantitative information in medical images,especially.that which is not visible to the naked ey.,is often ignored during clinical *** contrast,radiomics performs high-throughput feature extraction from medical images,which enables quantitative analy.is of medical images and prediction of various clinical *** have reported that radiomics exhibits promising performance in diagnosis and predicting treatment responses and prognosis,demonstrating its potential to be a non-invasive auxiliary.tool for personalized ***,radiomics remains in a developmental phase as numerous technical challenges have y.t to be solved,especially.in feature engineering and statistical *** this review,we introduce the current utility.of radiomics by.summarizing research on its application in the diagnosis,prognosis,and prediction of treatment responses in patients with *** focus on machine learning approaches,for feature extraction and selection during feature engineering and for imbalanced datasets and multi-modality.fusion during statistical ***,we introduce the stability.reproducibility.and interpretability.of features,and the generalizability.and interpretability.of ***,we offer possible solutions to current challenges in radiomics research.

关键词： Artificial intelligence Radiomics Feature extraction Feature selection Modeling Interpretability Multimodalities Head and neck cancer

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含苯并菲盘状液晶聚炔的相结构

含苯并菲盘状液晶聚炔的相结构

2010年两岸三地高分子液晶态与超分子有序结构学术研讨会（暨第十一次全国高分子液晶态与超分子有序结构学术论文报告会）

作者：余振强朱才镇刘剑洪 lam jacky.w.y. 赵可清唐本忠深圳大学化学与化工学院深圳市功能高分子重点实验室香港科技大学化学系四川师范大学化学与材料科学学院

盘状液晶材料在光存储、有机半导体、光电导体、光电池电荷传输材料及液晶显示材料等方面显示出巨大的应用前景。聚乙炔等具有刚性主链的侧链液晶高分子的相结构与相转变的研究对理解高分子液晶凝聚态结构具有重要意义。单取代侧链液晶... 详细信息

盘状液晶材料在光存储、有机半导体、光电导体、光电池电荷传输材料及液晶显示材料等方面显示出巨大的应用前景。聚乙炔等具有刚性主链的侧链液晶高分子的相结构与相转变的研究对理解高分子液晶凝聚态结构具有重要意义。单取代侧链液晶聚炔的本体相行为的研究表明,具有刚性主链的侧链液晶聚炔以整个分子形成

关键词：聚炔盘状液晶相结构 X-射线衍射

侧链含苯并菲盘状液晶基元的侧链液晶聚炔的相行为

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侧链含苯并菲盘状液晶基元的侧链液晶聚炔的相行为

2011年全国高分子学术论文报告会

作者：余振强朱才镇刘剑洪 lam jacky.w.y. 赵可清唐本忠深圳大学化学与化工学院香港科技大学化学系四川师范大学化学与材料科学学院

＜正＞单取代侧链液晶聚炔的本体相行为的研究表明,当主链为顺式构型时,分子形状为刚性柱状结构,柱状分子通过堆砌可以形成柱状液晶相;当主链为反式构型时,分子形状为片状结构,片状结构之间堆积形成近晶相。本文以侧链含苯并菲盘状液晶... 详细信息

＜正＞单取代侧链液晶聚炔的本体相行为的研究表明,当主链为顺式构型时,分子形状为刚性柱状结构,柱状分子通过堆砌可以形成柱状液晶相;当主链为反式构型时,分子形状为片状结构,片状结构之间堆积形成近晶相。本文以侧链含苯并菲盘状液晶基元的侧

关键词：聚炔盘状液晶相结构 X-射线衍射

具有不同液晶基元的双取代聚炔的相转变与相结构

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具有不同液晶基元的双取代聚炔的相转变与相结构

2009年全国高分子学术论文报告会

作者：余振强朱才镇刘剑洪陈尔强 lam jacky.w.y. 唐本忠深圳大学化学与化工学院北京大学化学与分子工程香港科技大学化学系

＜正＞单取代侧链液晶聚炔的本体相行为的研究表明,当主链为螺旋的顺式-顺式、顺式-反式构象时将形成刚性棒状结构,进而形成柱状液晶相;当主链为反式-顺式、反式-反式构象时形成片状结构,片状结构之间堆积形成近晶相。即单取代侧链液晶... 详细信息

＜正＞单取代侧链液晶聚炔的本体相行为的研究表明,当主链为螺旋的顺式-顺式、顺式-反式构象时将形成刚性棒状结构,进而形成柱状液晶相;当主链为反式-顺式、反式-反式构象时形成片状结构,片状结构之间堆积形成近晶相。即单取代侧链液晶聚炔是以整个分子形成的棒状

关键词：聚炔液晶高分子相转变相结构

A novel classification method for mild adolescent idiopathic scoliosis using 3D ultrasound imaging

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Medicine in Novel Technology.and Devices 2021年第3期11卷 151-161页

作者： D.y.ng T.T.y.Lee K.K.L.Lai y.S.wong L.N.wong J.L.y.ng T.P.lam R.M.Castelein J.C.y.Cheng y.P.Zheng Department of Biomedical Engineering The Hong Kong Polytechnic UniversityHong KongChina SH Ho Scoliosis Research Lab Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing UniversityDepartment of Orthopaedics&TraumatologyThe Chinese University of Hong KongHong KongChina Department of Orthopaedic Surgery University Medical Center Utrechtthe Netherlands Spine Center Xinhua Hospital Affiliated to Shanghai Jiaotong University School of MedicineShanghaiChina

Mild adolescent idiopathic scoliosis(AIS),with Cobb<20°,was hy.othesized as the right stage to intervene to prevent *** curve can be categorized into either structural or non-structural depending on the spine morphol... 详细信息

Mild adolescent idiopathic scoliosis(AIS),with Cobbwas hy.othesized as the right stage to intervene to prevent *** curve can be categorized into either structural or non-structural depending on the spine morphology.flexibility..Using X-ray.to characterize AIS curves remains the clinical gold standard whilecompromising the risks of radiation *** previous works,3D ultrasound imaging had proved the reli-ability.of the coronal spinal curvature measurement This research aimed at developing a mild AIs clasificationscheme through examining spine flexibility.using 3D ultrasound *** the preliminary.study.90 mild AIS subjects(21 M and 69 F;Age:14.5±1.7 y.ars old;Cobb:18.2±6.4°)underwent both 3D ultrasound and X-ray.scanning on the same *** each case,a clinician measured Cobbs and denoted major curve as ground *** Asy.metry.Index(BAl)was developed to indicate the presence of a possible structural *** curve classification was coded to a modfied Lenke classification for mild cases(m-Lenke).The results of 3D ultrasound classification were evaluated with the *** was shown that 70.1%of the subjects had identical curve clssification results and 72.0%had the correct major curve ***-dominated curves had distinctive performance(p=0.91,r=0.91)against *** study.demonstrated the possibility.of a 3D ultrasound-based method for mild AIS curve *** could be partially.explained by.the limitations of the ultrasound scanning in proximal thoracicreg *** studies will validate the proposed method with a larger cohort.

关键词： AIS classification 3D ultrasound Mild AIS Spine flexibility

Treatment Effects of Acupuncture and Calligraphy.Training on Cognitive Abilities in Senile Demented Patients

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Chinese Medicine and Culture 2019年第2期2卷 95-98页

作者： Henry.S.R.Kao Miqu wang Shuguang y. Shihong y.an Miranda My.Fung Lin Zhu Stewart P.w.lam Tin Tin Kao Xiaoy.ng Kao Departments of Psy.hology 9Psychology and GeographyUniversity of Hong KongHKSAR Calligraphy.Therapy.Research Laboratory Shenzhen Institute of NeuroscienceShenzhen Institute of Psy.hology.and Genetics of Chinese Medicine School of Acup uncture and Tuina Chengdu University of Traditional Chinese MedicineChengdu Department of Medicine Shanxi Medical College for Continuing Education Beijing Tong Ren Tang Chinese Medicine Clinic Beijing Tong Ren Tang Taiyuan Chinese Medicine Hospital Department of Chinese Medicine China Academy of Chinese Medical Sciences Division of Research Advocacy 21^st Century Education Research InstituteBeijingChina 不详 Department of Electrical Engineering University of Illinois at Urbana-ChampaignChampaignIllinoisUSA

Purpose:This study.compared the relative effectiveness of Chinese calligraphy.handwriting(CCH)and acupuncture in the treatment of patients with senile *** and Methods:A randomized controlled trial(RCT)with 17 mild-to-moderate dementia patients with an average age of 77.29 y.ars were randomly.assigned with 9 to the calligraphy.handwriting group and 8 to the acupuncture treatment group for a month of consecutive *** participants'cognitive abilities,as well as sy.ptoms of senile dementia,were measured by.the Chinese version of the Mini-mental State Examination(CMMSE)and the Chinese Medicine Quantitative Diagnostic Survey.for Senile Dementia Sy.ptoms,respectively.before and after the ***:The calligraphy.group showed a significant increase in calculation and memory.as well as a decline in the sy.ptoms of senile *** in the acupuncture group experienced a significant growth in total CMMSE scores and the subscales in orientation to time and place,behavioral operations,as well as reduced clinical ***,no significant changes were found in their memory.and calculation ***:Both CCH and acupuncture treatments were found significantly.effective for,respectively.enhancing the patients'cognitive abilities and reducing their clinical ***,calligraphy.handwriting also improved the level of their attention and concentration,phy.ical relaxation,and emotional stability.

关键词： Acupuncture calligraphy.handwriting cognitive abilities senile dementia

Uptake of prostate cancer screening and associated factors among Chinese men aged 50 or more: a population-based survey

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Cancer Biology.& Medicine 2014年第1期11卷 56-63页

作者： winnie K.w.So Kai Chow Choi winnie P.y.Tang Paul C.w.Lee Ann T.y.Shiu Simone S.M.Ho Helen y.L.Chan wendy.w.T.lam william B.Goggins Carmen w.H.Chan The Nethersole School of Nursing The Chinese University of Hong Kong Department of Community.Medicine The University of Hong Kong The Jockey.Club School of Public Health and Primary.Care The Chinese University of Hong Kong

Objective: To investigate the uptake rate of prostate specific antigen(PSA) testing among Hong Kong Chinese males aged 50 or above, and identify.factors associated with the likelihood of undergoing a PSA ***: A population-based telephone survey.was conducted in Hong Kong in 2007. The survey.covered demographic information, perceived health status, use of complementary.therapy. cancer screening behavior, perceived susceptibility.to cancer and family.history.of cancer. Descriptive statistics, percentages and logistic regression analy.is were used for data ***: A total of 1,002 men aged 50 or above took part in the study.response rate =67%), and the uptake rate of PSA testing was found to be 10%. Employ.ent status, use of complementary.therapy. perceiving regular visits to a doctor as good for health and the recommendations of health professionals were significant factors associated with PSA ***: The uptake rate of PSA testing in the study.population was very.low. Among all the factors identified, recommendations from health professionals had the strongest association with the uptake of PSA testing, and they.should therefore take an active role in educating this population about cancer prevention and detection.

关键词： Prostatic neoplasms early.detection of cancer prostate-specific antigen (PSA) population-based survey