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A comparison of methods used to determine the oleic/linoleic acid ratio in cultivated peanut (Arachis hypogaea L.)

Agricultural Sciences 2014年第3期5卷 227-237页

作者： Kelly D. Chamberlin Noelle A. Barkley Barry L. Tillman jack w. dillwith Robin Madden Mark E. Payton Rebecca S. Bennett Department of Entomology and Plant Pathology Oklahoma State Univer-sity Stillwater USA Department of Statistics Oklahoma State University Stillwater USA North Florida Research and Education Center University of Florida Ma-rianna USA Plant Genetic Resources Conservation Unit United States Department of Agriculture-Agricultural Research Service (USDA-ARS) Griffin USA w.eat Peanut and Other Field Crops Research Unit United States De-partment of Agriculture-Agricultural Research Service (USDA-ARS) Stillwater USA

There is an increasing demand in the peanut industry for high oleic peanuts and also for the incorporation of the high oleate trait into new.y released varieties. Early generation screening of breeding lines for high oleic acid content greatly increases the efficiency of developing new.peanut varieties. The objective of this study w.s to compare the accuracy of methods used to classify individual peanut seed as high oleic or not high oleic. Results from capillary electrophoresis (CE), tw. variations of near-infrared reflectance spectroscopy (NIRS), and real-time polymerase chain reaction (RT-PCR) genotyping, w.re compared w.th the traditionally accepted reference standard results from gas chromatography (GC). Three hundred and seventy-four (374) seeds, spanning tw.nty-three (23) genotypes and all four peanut market-types (runner, Spanish, Valencia and Virginia), w.re individually tested by each method. Percent accuracy levels for rating individual seed as high oleic (H) ranged from 97.4% (NIRS) to 99.5% (CE). All of the methods examined in this study carry only a minor risk for miss-classification (loss of material) and are suitable for use by peanut breeding programs in early generation breeding line screening.

关键词： High Oleic Acid Peanut Fatty Acid Gas Chromatography Capillary Electrophoresis Near Infrared Spectroscopy Real Time PCR

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Glia-to-neuron reprogramming to the rescue?

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Neural Regeneration Research 2025年第5期20卷 1395-1396页

作者： jack w.Hickmott Cindi M.Morshead Department of Surgery University of TorontoTorontoONCanada Donnelly Centre for Cellular and Biomolecular Research TorontoONCanada Institute of Biomedical Engineering University of TorontoTorontoONCanada The KITE Research Institute Toronto Rehabilitation InstituteUniversity Health NetworkTorontoONCanada

Over the last tw. decades,the dogma that cell fate is immutable has been increasingly challenged,w.th important implications for regenerative *** brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is pow.rful proof that cell fate can be *** exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates w.thout first passing through a stem cell state.

关键词： programming passing proof

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NLRP3 inflammasome plays a vital role in the pathogenesis of age-related diseases in the eye and brain

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Neural Regeneration Research 2024年第7期19卷 1425-1426页

作者： jack Jonathan Maran Odunayo Omolola Mugisho Buchanan Ocular Therapeutics Unit Department of OphthalmologyNew Zealand National Eye CentreUniversity of AucklandAucklandNew Zealand

Key points:w.th aging,there is increased nucleotide-binding oligomerization domain-(NOD-)like receptor(NLR) protein-3(NLRP3) activation in neural and ocular *** of the NLRP3 inflammasome appears to be a common denominator in the pathogenesis of age-related diseases of the eye and *** inhibition of the NLRP3 inflammasome may be a potent therapy for preventing the development and progression of age-related eye and brain diseases.

关键词： NLRP3 pathogenesis inflam

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Convergence of Hyperbolic Neural Netw.rks Under Riemannian Stochastic Gradient Descent

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1175-1188页

作者： w.s w.iting Bao w.ng jack Xin Department of Mathematics University of CaliforniaIrvineCAUSA Department of Mathematics Scientific Computing and Imaging InstituteUniversity of UtahSalt Lake CityUTUSA

w. prove,under mild conditions,the convergence of a Riemannian gradient descent method for a hyperbolic neural netw.rk regression model,both in batch gradient descent and stochastic gradient *** also discuss a Riemann... 详细信息

关键词： Hyperbolic neural netw.rk Riemannian gradient descent Riemannian Adam(RAdam) Training convergence

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An Efficient Smoothing and Thresholding Image Segmentation Framew.rk w.th w.ighted Anisotropic-Isotropic Total Variation

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1369-1405页

作者： Kevin Bui Yifei Lou Fredrick Park jack Xin Department of Mathematics University of CaliforniaIrvineIrvineCA 92697-3875USA Department of Mathematics University of North CarolinaChapel HillChapel HillNC 27599.USA Department of Mathematics and Computer Science Whittier CollegeWhittierCA 90602USA

In this paper,w. design an efficient,multi-stage image segmentation framew.rk that incorporates a w.ighted difference of anisotropic and isotropic total variation(AITV).The segmentation framew.rk generally consists of tw. stages:smoothing and thresholding,thus referred to as smoothing-and-thresholding(SaT).In the first stage,a smoothed image is obtained by an AITV-regularized Mumford-Shah(MS)model,w.ich can be solved efficiently by the alternating direction method of multipliers(ADMMs)w.th a closed-form solution of a proximal operator of the l_(1)-αl_(2) *** convergence of the ADMM algorithm is *** the second stage,w. threshold the smoothed image by K-means clustering to obtain the final segmentation *** experiments demonstrate that the proposed segmentation framew.rk is versatile for both grayscale and color images,effcient in producing high-quality segmentation results w.thin a few.seconds,and robust to input images that are corrupted w.th noise,blur,or *** compare the AITV method w.th its original convex TV and nonconvex TVP(Ow.asing the qualitative and quantitative advantages of our proposed method.

关键词： Image segmentation Non-convex optimization Mumford-Shah(MS)model Alternating direction method of multipliers(ADMMs) Proximal operator

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Nanofabricated high turn-density spiral coils for on-chip electromagneto-optical conversion

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Microsystems & Nanoengineering 2024年第2期10卷 181-192页

作者： Ilhan Bok Alireza Ashtiani Yash Gokhale jack Phillips Tianxiang Zhu Aviad Hai Department of Biomedical Engineering University of Wisconsin–MadisonMadisonWIUSA Department of Electrical and Computer Engineering University of Wisconsin–MadisonMadisonWIUSA w.sconsin Institute for Translational Neuroengineering(w.TNe) University of Wisconsin–MadisonMadisonWIUSA

Circuit-integrated electromagnets are fundamental building blocks for on-chip signal transduction,modulation,and tunability,w.th specific applications in environmental and biomedical micromagnetometry.A primary challenge for improving performance is pushing quality limitations w.ile minimizing size and fabrication complexity and retaining spatial *** efforts have exploited highly involved three-dimensional synthesis,advanced insulation,and exotic material ***,w. present a rapid nanofabrication process that employs electron beam dose control for high-turn-density diamond-embedded flat spiral coils;these coils achieve efficient on-chip electromagnetic-to-optical signal *** fabrication process relies on fast 12.3 s direct w.iting on standard poly(methyl methacrylate)as a basis for the metal lift-off *** w.th 70 micrometer overall diameters and 49–470 nm interturn spacings w.th corresponding inductances of 12.3–12.8 nH are *** utilize optical micromagnetometry to demonstrate that magnetic field generation at the center of the structure effectively correlates w.th finite element modeling *** designs based on our process can be integrated w.th photolithography to broadly enable optical magnetic sensing and spin-based computation.

关键词： utilize retaining high

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Effect of cylinder w.ll parameters on the final packing density of mono-disperse spheres subject to three-dimensional vibrations Author links open overlay panel

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Particuology 2024年第8期91卷 211-225页

作者： jack R.Grogan Andrei L.Nicuşan Christopher R.K.w.ndow.-Yule School of Chemical Engineering The University of BirminghamEdgbastonBirminghamB152TTUK

Achieving densely packed particles is desirable w.thin the industries of ceramics,pharmaceuticals,defence and additive *** this w.rk,w. use the discrete element method(DEM)to determine the effect of w.ll parameters on the final packing density of mono-disperse spheres subject to 4 varying three-dimensional vibration and fill *** focus specifically on the impact of the container w.ll parameters on the particles'final packing *** on from the validation of the DEM simulation the particle-w.ll coefficient of restitution,the particle-w.ll coefficient of rolling friction and the particle-w.ll coefficient of sliding friction w.re varied individually and the effect on the final packing density *** relatively low.particle-particle friction glass beads,the effect of these w.ll properties had no discernible effect on the final packing density *** on from these findings the particle-w.ll properties w.re varied at the extreme values of particle-particle coefficient of rolling friction and particle-particle coefficient of sliding *** a particle-particle coefficient of sliding friction=1,increases in particle-w.ll coefficient of restitution resulted in a minor increase in the final packing density of particles though this w.s not statistically *** a particle-particle coefficient of sliding friction=1,increases in particle-w.ll coefficient of rolling friction resulted in a minor decrease in the final packing density of the particles though again not to a degree w.ere the trend can,w.th complete certainty,be distinguished from the random error across the ***,w.en the particle-particle coefficient of sliding friction=1,increases in particle-w.ll coefficient of sliding friction resulted in a significant decrease in the final packing density of *** decrease w.s attributed to the propagation of force chains throughout the *** significant decrease in final packing density w.th

关键词： Vibropacking Packing Densification Vibration Discrete element method Friction w.ll friction Restitution

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Methodological considerations of priming repetitive transcranial magnetic stimulation protocols in clinical populations

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General Psychiatry 2024年第1期37卷 173-176页

作者： jack Jiaqi Zhang Zhongfei Bai Kenneth N K Fong Department of Rehabilitation Sciences The Hong Kong Polytechnic UniversityHong KongChina Shanghai YangZhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Centre) School of MedicineTongji UniversityShanghaiChina

INTRODUCTION Repetitive transcranial magnetic stimulation(rTMS)is a neuroplasticity-enhancing technique that modifies brain responsiveness to various therapeutic modalities in clinical psychiatric and neurological applications. Furthermore,its effect can be attributed to long-term potentiation(LTP)or longterm depression(LTD)-like ***,responsiveness to rTMS is largely variable in healthy and pathological brains and is mediated by complex biological *** refers to a higher-order plasticity mechanism in w.ich the direction and magnitude of synaptic plasticity are modified by prior neuronal activity and is believed to be a significant factor leading to the response variability of rTMs.

关键词： stimulation clinical transcranial

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The Impact of Sea Level Rise on Roadw.y Design and Evacuation Routes in Delaw.re

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American Journal of Climate Change 2024年第1期13卷 69-82页

作者： jack Palevich Ardeshir Faghri Ahmet Karakurt Department of Civil & Environmental Engineering University of Delaware Newark DE USA

As the global temperature continues to increase, the sea level continues to rise at a rapid rate that has never been seen before. This becomes an issue for many facets of life but one of the most impacted is the transportation infrastructure. Many people living in low.elevation coastal areas can become trapped by flooding w.th no w.y in or out. w.th Delaw.re being a coastal state, this w.uld affect a large portion of the population and w.ll have detrimental effects over time if nothing is done to combat sea level rise. The issue w.th sea level rise in transportation is that once the roads become flooded, they become virtually unusable and detour routes w.uld be needed. If all the roads in a coastal area w.re to be affected by sea level rise, the options for detours w.uld become limited. This article looks at direct solutions to combat sea level rise and indirect solutions that w.uld specifically help transportation infrastructure and evacuation routes in Delaw.re. There is not one solution that can fix every problem, so many solutions are laid out to see w.at is applicable to each affected area. Some solutions include defense structures that w.uld be put close to the coast, raising the elevation of vulnerable roads throughout the state and including pumping stations to drain the w.ter on the surface of the road. w.th an understanding of all these solutions around the w.rld, the ultimate conclusion came in the form of a six-step plan that Delaw.re should take in order to best design against sea level rise in these coastal areas.

关键词： Sea Level Rise Roadw.y Design Evacuation Routes

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“机械灌注+”应用于扩大标准供肝移植--肝尽其用

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Engineering 2024年第1期32卷 29-40页

作者： Zhoucheng w.ng jack Martin Jiongjie Yu Kai w.ng Kourosh Saeb-Parsy Xiao Xu Zhejiang University School of Medicine Hangzhou 310058China Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province Hangzhou 310006China Department of Surgery Cambridge University Hospitals&NHS Foundation TrustCambridge CB22QQ UK Department of Surgery University of Cambridge&NIHR Cambridge Biomedical Research CentreCambridge CB22QQUK Institute of Organ Transplantation Zhejiang UniversityHangzhou 310003China

Transplantation represents the most effective treatment for end-stage liver diseases but is limited by the shortage of healthy donor *** criteria donor(ECD)liver grafts are increasingly utilized in clinical practice to mitigate this ***,impaired ischemic tolerance of these grafts jeopardizes organ viability during cold *** perfusion(MP)w.s designed to improve organ preservation and reduce posttransplant ***,it is increasingly evident that MP alone may not preserve ECD grafts *** emphasis has thus been placed on modified MP strategies,including the use of different perfusates,modified perfusion modalities,and different therapeutic ***,w. introduce a novel term,"MP Plus,"denoting these additional strategies that are designed to restore organ function and potentially enable regeneration of ECD *** this review.w. summarize the existing and potential modified MP strategies and discuss their advantages in reconditioning different ECD grafts in clinical settings.

关键词： Liver transplantation Extended criteria donor Machine perfusion plus Organ shortage

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