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出生前母亲暴露于重复剂量的糖皮质激素与出生后新生儿心血管状态的改变有关

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世界核心医学期刊文摘（儿科学分册） 2006年第5期2卷 18-18页

作者： Mildenhall.l.F.J. Battin M.R. Morton S.M.B. J.E. Harding 俞晓梅 liggins Institute Faculty of Medical and Health Science University of Auckland Private Bag 92019 Auckland New Zealand.Prof

Objective: To determine if exposure to more than one course of antenatal gluco cortlcoids is associated with changes in infant blood pressure and myocardial wa ll thickness in the first month after birth. Design: Prospective cohort study. S etting: Tertiary neonatal intensive care unit. Participants: Mothers who were el igible for but declined to enter a randomised trial of repeated doses of antenat al glucocorticoids (ACTORDS)-that is, who had a singleton, twin, or triplet pre gnancy at estation, had received an initial course of glucocorticoid s seven or more days previously, and were considered to be at continued risk of preterm birth. Main outcome measures: Blood pressure daily for the first week th en weekly until 4 weeks of age. End diastolic interventricular septal and left v entricular posterior wall (EDIVS and EDlVPW) thickness at 48-72 hours after bir th. Results: Thirty seven women were enrolled and delivered 50 infants. Thirty m others (39 infants) were exposed to one course of glucocorticoids, and seven mot hers (11 infants) to more than one course. Blood pressures were higher in the fi rst week after birth in infants exposed to multiple courses of glucocorticoids, and in infants with a latency between last exposure and delivery of less than se ven days. Systolic blood pressure on day 1 was > 2SD above published normal rang es in 67%of babies exposed to multiple courses and 24%of babies exposed to a s ingle course of glucocorticoids (p = 0.04). There was no difference between grou ps in thickness of the EDIVS or EDlVPW. However, 44/50 (88%) babies had EDIVS a nd 49/50 (98%) babies had EDlVPW thickness > 2 SD above the expected mean for b irth weight and gestation. EDIVS but not EDlVPW thickness increased with increas ing latency (mean 0.02 mm/day, P=0.03). Conclusion: Future randomised trials sho uld assess the long term effects of exposure to antenatal glucocorticoids, particularly multiple courses, on the cardiovascular status of the infan

关键词：新生儿重症监护病房糖皮质激素母亲暴露重复剂量出生前出生后心血管状态前瞻性队列研究随机试验三胎妊娠

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A meshfree es-PIM for nonlinear transient heat transfer

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A meshfree ES-PIM for nonlinear transient heat transfer

Tip-and laser-based 3D Nanofabrication in Extended Macroscopic Working Areas

第三届亚太国际工程中计算方法学术会议ICOME2009暨第九届全国工程中边界元、无网格等数值方法学术会议

作者： S. C. Wu a,b,*, G. R. liub,c, W. l. Chena, X. Y. Cuib,d aCentre for Advanced Materials Joining & Computations (AMJC), School of Materials Science and Engineering, Hefei University of Technology, Hefei, 230009, PR China bCentre for Advanced Computations in Engineering Science (ACes), Department of Mechanical Engineering, National University of Singapore, 117576 Singapore cSingapore-MIT Alliance (SMA), E4-04-10, 4 Engineering Drive 3, 117576 Singapore dState Key laboratory of Advanced Technology for Vehicle Body Design & Manufacture, Hunan University, Changsha, 410082 PR China

A meshfree edge-based smoothed point interpolation methods (es-PIM) is formulated to analyze the nonlinear heat transfer problems in two-dimensions. The nonlinearities arising from the variation of material properties and surface convection coefficients and those due to the inclusion of the radiation effects are fully considered. The PIM is used to approximate the temperature function and the thermal gradient field within edge-based smoothed domains is modified by a generalized gradient smoothing technique. To avoid iterations, quasilinearization scheme is adopted to linearize the nonlinear system equations, and for time integration the Euler backward method is used, as its unconditional stability allows for larger time steps. The smoothed incremental heat transfer equilibrium equations are then established using the generalized smoothed Galerkin weak form. A number of one- and two-dimensional heat transfer problems are studied in terms of the convergence in equivalent energy and the accuracy of temperature field. It is found that present es-PIM achieves more accurate temperature results and better convergence than FEM and NS-PIM do using the same triangular background meshes and can effectively simulate complex nonlinear heat transfer problems.

关键词： Meshfree methods Nonlinear transient heat transfer Convection Radiation Gradient smoothing technique Element-free Galerkin method.

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Nanomanufacturing and Metrology 2021年第3期4卷 132-148页

作者： Ingo Ortlepp Thomas Frohlich Roland FuBl Johann Reger Christoph Schaffel Stefan Sinzinger Steffen Strehle ReneTheska lena Zentner Jens-Peter Zollner Ivo WRangelow Carsten Reinhardt Tino Hausotte Xinrui Cao Oliver Dannberg Florian Fern David Fischer Stephan Gorges Martin Hofmann Johannes Kirchner Andreas Meister Taras Sasiuk Ralf Schienbein Shraddha Supreeti laura Mohr-Weidenfeller Christoph Weise Christoph Reuter jaqueline Stauffenberg Eberhard Manske Institute of Process Measurement and Sensor Technology Technische Universitat IlmenauEhrenbergstrasse 2998693 IlmenauGermany Control Engineering Group Technische Universitat IlmenauIlmenauGermany Optical Engineering Group.Technische Universitat Ilmenau IlmenauGermany Microsystems Technology Group.Technische Universitat Ilmenau IlmenauGermany Precision Engineering Group.Technische Universitat Ilmenau IlmenauGermany Compliant Systems Group Technische Universitat IlmenauIlmenauGermany Micro-and Nanoelectronic Systems Group Technische Universitat IlmenauIlmenauGermany Nanoscale Systems Group.Technische Universitat Ilmenau IlmenauGermany Division for Research Service and Technology Transfer Technische Universitat IlmenauIlmenauGermany Electronics Technology Group.Technische Universitat Ilmenau IlmenauGermany IMMS Institut flir Mikroelektronik-und Mechatronik-Systeme Gemeinniitzige GmbH(IMMS GmbH) IlmenauGermany Fachgebiet Technische Physik City University of Applied SciencesBremenGermany lehrstuhl fiir Fertigungsmesstechnik Friedrich-Alexander-U niversitat(FAU)Erlangen-NiirnbergGermany JUMO GmbH&Co.KG FuldaGermany Asphericon GmbH JenaGermany

The field of optical.l.thography is subject to intense research and has gained enormous ***,the effort necessary for creating structures at the size of 20 nm and below is considerable using conventional *** effort and the resulting financial requirements can only be tackled by few global companies and thus a paradigm change for the semiconductor industry is conceivable:custom design and solutions for specific applications will dominate future development(Fritze in:Panning EM,liddle ja(eds)Novel patterning *** society for optics and ***,Bellingham,***://***/10.1117/12.2593229).For this reason,new aspects arise for future lithography,which is why enormous effort has been directed to the development of alternative fabrication ***,the technologies emerging from this process,which are promising for coping with the current resolution and accuracy challenges,are only demonstrated as a proof-of-concept on a lab scale of several square *** scale is not adequate for the requirements of modern lithography;therefore,there is the need for new and alternative cross-scale solutions to further advance the possibilities of unconventional *** challenges arise because of the technical progress in various other fields,realizing new and unique functionalities based on nanoscale effects,e.g.,in nanophotonics,quantum computing,energy harvesting,and life *** platforms for basic research in the field of scale-spanning nanomeasuring and nanofabrication are necessary for these tasks,which are available at the Technische Universitiit Ilmenau in the form of nanopositioning and nanomeasuring(NPM)*** this equipment,the limits of technical structurability are explored for high-performance tip-based and laser-based processes for enabling real 3D nanofabrication with the highest precision in an adequate working range of several thousand cubic millimete

关键词： Nanomeasuring Nanopositioning Nanomanufacturing Scale-spanning Tip-based laser-based Nanofabrication

In Vitro Konstruktion und Erfolgreiche Transplantation von Kryokonservierten Membran-Zel-Transplantaten(MZT) auf Vollhautwunden Athymischer Nacktmuse

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暨南大学学报(自然科学与医学版) 1998年第6期 158-158页

作者： Kopp, J 1,2) Jiao, X.Y. 1,3) Chen, Y.l. 1,2) Stark, G.B. 1,2,3) (1) Abteilung Plastische und Handchirurgie, Chirurgische Universiltsklinik, Freiburg l. Brsg, Germany 2) Verbrennungszentrum, Changhai Hosptital, Second Military Medical University, Shanghai,P.R. China) 3) Abteilung Plastische Chirurgie, Changhai Hospital, Second Militray Medical University, Shanghai, P.R.China)

Ｋｏｐｐ，Ｊ１，２）Ｊｉａｏ，Ｘ．Ｙ．１，３）Ｃｈｅｎ，Ｙ．Ｌ．１，２）Ｓｔａｒｋ，Ｇ．Ｂ．１，２，３）（１）ＡｂｔｅｉｌｕｎｇＰｌａｓｔｉｓｃｈｅｕｎｄＨａｎｄｃｈｉｒｕｒｇｉｅ，ＣｈｉｒｕｒｇｉｓｃｈｅＵｎｉｖｅ... 详细信息

Ｋｏｐｐ，Ｊ１，２）Ｊｉａｏ，Ｘ．Ｙ．１，３）Ｃｈｅｎ，Ｙ．Ｌ．１，２）Ｓｔａｒｋ，Ｇ．Ｂ．１，２，３）（１）ＡｂｔｅｉｌｕｎｇＰｌａｓｔｉｓｃｈｅｕｎｄＨａｎｄｃｈｉｒｕｒｇｉｅ，ＣｈｉｒｕｒｇｉｓｃｈｅＵｎｉｖｅｒｓｉｌｔｓｋｌｉｎｉｋ，Ｆｒｅｉ...

关键词： In Vitro Erfolgreiche Athymischer

Measurement of Reaction Cross Section at Intermediate Energies for Neutron-Deficient Nuclei(A<30)and Possible Proton Halo Structure on 23Al and 27P

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Measurement of Reaction Cross Section at Intermediate Energi...

小鼠淋巴细胞白血病（Ｐ３８８）生物学特性的研究

CCAST“放射性束物理”研讨会

作者： X.Z. Cai, W.Q. Shen, Z.Z. Ren, D.Q. Fang, H.Y. Zhang, J. Feng, Z.Y.Zhu, W.Z. Jiang, Y.G. Ma, C. ZhongW.l. Zhan, Z.Y. Guo, G.Q. Xiao, J.S. Wang, Y.T. Zhu, J.C. Wang, J.X. li, M. Wang, Q.J. Wang, Z.Q.Chen, J.F. Wang, Z.J. Ning’Shanghai Institute of Nuclear Research, Chinese Academy of Sciences,Shanghai 201800, China 2CCAST(Worl.l.boratory) P.O.Box 8730, Beijing WOOSO.China .Institute of Modern Physics, Chinese Academy of Sciences, lanzhou730000, ChinaPhysics Department of Nanjing University, Nanjing 210008, ChinaPhysics Department ofNingbo University, Ningbo 315211, China

Reaction cross section σ of proton-rich isoto谱es (A<30) on C target have beenmeasured at intermediate energies around 30MeV/u by a transmission *** increases of the experimentalσ are observed for Al and P compared...

Reaction cross section σ of proton-rich isoto谱es (Aes around 30MeV/u by a transmission *** increases of the experimentalσ are observed for Al and P compared withtheir neighboring *** suggests that there is an anomalously large matter RMSradius in these nuclei. Together with their very weakly binding of the last proton,itindicates that there is a one-proton halo in Al and P. This conclusion is also supportedby the difference factor d which is deduced from the measured and theoreticalσ in theGlauber or BUU model and is used for the manifest of halo phenomena. The theoreticalcalculation based on the RDDH model also shows that there is a one proton halo in Pand in Al when the last proton of Al is in the 2s orbit. The significance of theproton halo in Al is discussed.

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北京实验动物科学 1993年第1期10卷 1-5页

作者：欧阳卓志王红兵李革张呈生刘亚莉刘增华李广粹中国医学科委实验动物研究所

对从国外引进的小鼠淋巴细胞白血病(P388)的生物学特性进行了观察,实验结果表明以DBA/2近交小鼠为宿主,腹腔播种小鼠淋巴细胞白血病(P388)瘤细胞悬液,传代宜用第6一8天荷瘤鼠之腹水,每只鼠接种瘤细胞数宜大于1OO万。其接种成活率为98.6%... 详细信息

对从国外引进的小鼠淋巴细胞白血病(P388)的生物学特性进行了观察,实验结果表明以DBA/2近交小鼠为宿主,腹腔播种小鼠淋巴细胞白血病(P388)瘤细胞悬液,传代宜用第6一8天荷瘤鼠之腹水,每只鼠接种瘤细胞数宜大于1OO万。其接种成活率为98.6%,有1.4%的自发消退.肿瘤生长潜伏期3-4天,第4～6天为缓慢生长期,第6-12天为迅速生长期,瘤细胞的倍增期略早于腹水的倍增期.第12天后,动物呈明显恶液质状态并进入濒死期,宿主平均存活14.7±3.21天。自第6日起荷瘤小鼠平均每日腹水增长1.26ml.至第14日,平均腹水总量可达12-13ml.

关键词：小鼠白血病 P388 生物学我特性

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