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Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

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Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： He-Xin Liu Yue huang guang-Cheng Xiao Qing-Cui Bu jin-lu Qu shu Zhang Shuang-Nan Zhang shu-Mei Jia Fang-Jun lu Xiang Ma Lian Tao Wei Zhang Li Chen Li-Ming Song Ti-Pei Li Yu-Peng Xu Xue-Lei Cao Yong Chen Cong-Zhan Liu Ce Cai Zhi Chang Gang Chen Tian-Xiang Chen Yi-Bao Chen Yu-Peng Chen Wei Cui Wei-Wei Cui jing-Kang Deng Yong-Wei Dong Yuan-Yuan Du Min-Xue Fu Guan-hua Gao He Gao Min Gao Ming-Yu Ge Yu-Dong Gu Ju Guan Cheng-Cheng guo Da-Wei Han Jia Huo lu-hua jiang Wei-Chun jiang jing jin Yong-Jie jin Ling-Da Kong Bing Li Cheng-Kui Li Gang Li Mao-shun Li Wei Li Xian Li Xiao-Bo Li Xu-Fang Li yang-guo Li Zheng-Wei Li Xiao-hua Liang jing-Yuan Liao Bai-Sheng Liu guo-Qing Liu Hong-Wei Liu Xiao-jing Liu Yi-Nong Liu Bo lu Xue-Feng lu Qi luo Tao luo Bin Meng Yi Nang jian-Yin Nie Ge Ou Na Sai Ren-Cheng Shang Xin-Ying Song Liang sun Ying Tan You-Li Tuo Chen wang guo-Feng wang Juan wang Ling-Jun wang Weng-Shuai wang Yu-Sa wang Xiang-yang Wen Bai-yang Wu Bo-Bing Wu Mei Wu shuo Xiao shao-Lin Xiong He Xu Jia-Wei yang Sheng yang yan-Ji yang Yi-Jung yang Qi-Bin Yi Qian-Qing Yin Yuan You Ai-Mei Zhang Cheng-Mo Zhang Fan Zhang Hong-Mei Zhang Juan Zhang Tong Zhang wan-Chang Zhang Wen-Zhao Zhang Yi Zhang Yi-Fei Zhang Yong-Jie Zhang Yuan-Hang Zhang Yue Zhang Zhao Zhang Zhi Zhang Zi-Liang Zhang Hai-Sheng Zhao Xiao-Fan Zhao Shi-Jie Zheng Yao-guang Zheng Deng-Ke Zhou jian-Feng Zhou Yu-Xuan Zhu Ren-Lin Zhuang Yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients

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Chinese Medical Journal 2013年第12期126卷 2276-2280页

作者： ZHENG Ying CAI guang-yan CHEN Xiang-mei FU ping CHEN jiang-hua DING Xiao-qiang YU Xue-qing LIN Hong-li LIU jian XIE Ru-juan wanG Li-ning NI Zhao-hui LIU Fu-you YIN Ai-ping XING Chang-ying wanG Li SHI Wei LIU jian-she HE Ya-ni DING guo-hua LI Wen-ge WU guang-li MIAO Li-ning CHEN Nan SU Zhen MEI Chang-lin ZHAO Jiu-yang GU Yong BAI Yun-kai luO Hui-min LIN Shan CHEN Meng-hua GONG Li yanG Yi-bin yanG Xiao-ping LI Ying wan jian-xin wanG Nian-song LI Hai-ying XI Chun-sheng HAO Li XU yan FANG jing-ai LIU Bi-cheng LI Rong-shan wanG Rong ZHANG jing-hong wanG jian-qin LOU Tan-qi shao Feng-min MEI Feng LIU Zhi-hong YUAN Wei-jie sun Shi-ren ZHANG Ling ZHOU Chun-hua CHEN Qin-kai JIA shun-lian GONG Zhi-feng GUAN guang-ju XIA Tian ZHONG Liang-bao Department of Nephrology State key Laboratory of Kidney Disease Chinese PLA General Hospital Beijing 100853 China Nephrology Institute of the Chinese People's Liberation Army Chinese People's Liberation Army Key Laboratory of Nephrology Beijing 100853 China Department of Nephrology West China Hospital of Sichuan University Chengdu Sichuan 610041 China Department of Nephrology First Affiliated Hospital School of Medicine Zhejiang University Hangzhou Zhejiang 310003 China Department of Nephrology Zhongshan Hospital Fudan University Shanghai 200032 China Department of Nephrology First Affiiated Hospital of Sun Yat-sen University Guangzhou Guangdong 510080 China Department of Nephrology First Affiliated Hospital of Dalian Medical University Dalian Liaoning 116011 China Department of Nephrology First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 China Department of Nephrology First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang 150001 China Department of Nephrology First Afftiated Hospital of China Medical University Shenyang Liaoning 110001 China Department of Nephrology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200025 China Department of Nephrology Second Xiangya Hospital Central South University Changsha Hunan 410000 China Department of Nephrology First Affiliated Hospital of Medical College Xi'an Jiaotong University Xi'an Shaanxi 710061 China Department of Nephrology First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital) Nanjing Jiangsu 210029 China Department of Nephrology Sichuan Provincial People's Hospital Chengdu Sichuan 610072 China Department of Nephrology Guangdong Provincial People's Hospital Guangzhou Guangdong 510030 China Department of Nephrology Affliated Xiehe Hospital Tongji Medical College Huazhong Science and Technology University Wuhan Hubei 430022 China Department of Nephrology Daping Hospital Third Military Medi

Background Data on the epidemiology of hypertension in Chinese non-dialysis chronic kidney disease （CKD） patients are *** aim of the present study was to investigate the prevalence,awareness,treatment,and control of hypertension in the non-dialysis CKD patients through a nationwide,multicenter study in *** The survey was performed in 61 tertiary hospitals in 31 provinces,municipalities,and autonomous regions in China （except Hong Kong,Macao,and Taiwan）.Trained physicians collected demographic and clinical data and measured blood pressure （BP） using a standardized *** was defned as systolic BP ≥140 mmHg and/or diastolic BP ≥90 mmHg,and/or use of antihypertensive *** 〈140/90 mmHg and 〈130/80 mmHg were used as the 2 thresholds of hypertension *** multivariate logistic regression with adjustment for sex and age,we analyzed the association between CKD stages and uncontrolled hypertension in non-dialysis CKD *** The analysis included 8927 non-dialysis CKD *** prevalence,awareness,and treatment of hypertension in non-dialysis CKD patients were 67.3%,85.8%,and 81.0%,*** hypertensive CKD patients,33.1% and 14.1% had controlled BP to 〈140/90 mmHg and 〈130/80 mmHg,*** successive CKD stages,the prevalence of hypertension in non-dialysis CKD patients increased,but the control of hypertension decreased （P〈0.001）.When the threshold of BP 〈130/80 mmHg was considered,the risk of uncontrolled hypertension in CKD 2,3a,3b,4,and 5 stages increased 1.3,1.4,1.4,2.5,and 4.0 times compared with CKD 1 stage,respectively （P〈0.05）.Using the threshold of 〈140/90 mmHg,the risk of uncontrolled hypertension increased in advanced stages （P〈0.05）.Conclusions The prevalence of hypertension Chinese non-dialysis CKD patients was high,and the hypertension control was *** successive CKD stages,the risk of uncontrolled hypertension increased.

关键词： non-dialysis chronic kidney disease chronic kidney disease stages hypertension epidemiology

Diagnosis and Treatment of Cholangiocarcinoma: A Consensus from Surgical Specialists of China

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Journal of huazhong University of Science and Technology(Medical Sciences) 2014年第4期34卷 469-475页

作者： jian-qiang Cai Shou-wang Cai Wen-ming Cong Min-shan Chen ping Chen Xiao-ping Chen yan-ling Chen Yi-fa Chen Chao-liu Dai Qiang huang Zhi-yong huang Bo jiang Bin jiang Ke-wei jiang Bo Li Zong-fangLi Li-jian Liang Bin Liu Hui-chun Liu Lian-xin Liu Qing-guang Liu Rong Liu Ying-bin Liu jian-guo lu Shi-chun lu Yi lu Yi-lei Mao Bin Mei Jun Niu Bao-gang Peng Xiao Qin Yu-dong Qiu guang-yi wang Yao-don wangg Zhi-ming wang Ren-hua wan Ya-fu Wu Bao-cai Xing Feng Xia Ge-liang Xu Jia-mei yang Xiao-fang Yu Yong Zeng Yong-yi Zeng Bi-xiang Zhang Bin-hao Zhang Qi-yu Zhang shui-jun Zhang wan-guang Zhang Yong-jie Zhang Zhi-wei Zhang Dong Zhou Wei-ping Zhou Cancer Institute and Hospital Chinese Academy of Medical Sciences Chinese PLA General Hospital Eastern Hepatobiliary Surgery Hospital of Second Military Medical University sun Yat-sen University Cancer Center Daping Hospital of Third Military Medical University Tongji Hospital Tongji Medical CollegeHuazhong University of Science and Technology Fujian Medical University Union Hospital Shengjing Hospital of China Medical University Anhui Provincial Hospital Hunan Provincial People’s Hospital Taihe Hospital Affiliated to Hubei University of Medicine Peking University People’s Hospital West China Hospital Sichuan University The Second Affiliated Hospital of Xi’an Jiao Tong University The First Affiliated Hospital Sun Yat-sen University First Affiliated Hospital of Kunming Medical University The First Affiliated Hospital of Bengbu Medical College The First Affiliated Hospital of Harbin Medical University The First Affiliated Hospital of Xi’an Jiao Tong University Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Tangdu Hospital of Fourth Military Medical University Peking Union Medical College Hospital Qilu Hospital of Shandong University The First Affiliated Hospital of guangxi Medical University Nanjing Drum Tower Hospital The First Affiliated Hospital of Jilin University Fujian Provincial Hospital Xiangya Hospital of Central South University The First Affiliated Hospital of Nanchang University Beijing Cancer Hospital Southwest Hospital of Third Military Medical University Shenzhen People’s Hospital The First Affiliated Hospital of Fujian Medical University The First Affiliated Hospital of Wenzhou Medical University The First Affiliated Hospital of Zhengzhou University Fujian Provincial Cancer Hospital

Cholangiocarcinoma refers to malignant tumors that develop in epithelial lining of biliary system, and it is divided into two categories according to tumor location, intrahepatic cholangiocarcinoma （ICC） and extrahepatic cholangiocarcinoma （ECC）. ICC occurs from the epithelial cells of the intrahepatic bile duct, its branches and interlobular biliary tree; and ECC is divided into hilar cholangiocarcinoma and distal cholangiocarcinoma by the circumscription at the confluence of cystic duct and the common hepatic duct.

关键词： A Consensus from Surgical Specialists of China Diagnosis and Treatment of Cholangiocarcinoma

Expert Consensus on Pathological Diagnosis of Intrahepatic Cholangiocarcinoma(2022 version)

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Journal of Clinical and Translational Hepatology 2023年第7期11卷 1553-1564页

作者： Han wang Jun Chen Xin Zhang Xia Sheng Xiao-yan Chang Jie Chen Min-Shan Chen Hui Dong guang-Jie Duan He-ping Hu Zhi-Yong huang Wei-Dong Jia Xiao-Qing jiang Dong Kuang Shan-Shan Li Zeng-Shan Li Chang-Li lu shu-Kui Qin Xue-Shan Qiu Li-Juan Qu Chun-Kui shao Feng Shen guo-Ming Shi Su-Sheng Shi Yu-Jun Shi Hui-Chuan sun Xiao-Dong Teng Bin wang Zhan-Bo wang Tian-Fu Wen Jia-Mei yang Qiao-Qiao yang Sheng-Long Ye Hong-Fang Yin Zhen-Gang Yuan jing-ping Yun Feng-Lin Zang Hong-Qi Zhang Li-Hong Zhang jing-Min Zhao jian Zhou Wei-Xun Zhou Jia Fan Xiao-ping Chen wan Yee Lau Yuan Ji Wen-Ming Cong Chinese Society of Liver Cancer of Chinese Anti-Cancer Association Digestive Disease Group of Chinese Society of Pathology,Chinese Medical Association Chinese Society of Pathology of Chinese Anti-Cancer Association Hepatic Surgery Group of Chinese Society of Surgery,Chinese Medical Association Biliary Tract Tumor Committee of China Anti-Cancer Association Chinese Society of Clinical Oncology IDepartment of Pathology Eastern Hepatobilary Surgery HospitalNaval Medical UniversityShanghaiChina Department of Pathology the Affiliated Drum Tower HospitalNanjing University Medical SchoolNanjingJiangsuChina Department of Pathology Zhongshan HospitalFudan UniversityShanghaiChina Department of Pathology Minhang HospitalFudan Uni-versityShanghaiChina Department of Pathology Peking Union Medical College HospitalChinese Academy of Medical Sci-ences and Peking Union Medical CollegeBeijingChina Department of Liver Surgery Sun Yat-Sen University Cancer CenterGuangzhouGuangdongChina Department of Pathology The First Affiliated HospitalArmy Medical UniversityChongqingChina Department of Hepatobiliary Medicine Eastern Hepatobiliary Surgery HospitalNaval Medical UniversityShanghaiChina Hepatic Surgery Center Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWu-hanHubeiChina Department of General Surgery The First Affliated Hospital of USTCDivision of Life Science and Medi-cineUniversity of Science and Technology of ChinaHefeiAnhuiChina Department of Biliary Surgery I Eastern Hepatobil-iary Surgery HospitalNaval Medical UniversityShanghaiChina Department of Pathology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubeiChina Department of Pathology The First Afiliated Hospital of Zhengzhou UniversityZhengzhou UniversityZhengzhouHenanChina Department of Pathology Xijing Hospi-talAir Force Medical UniversityXi'anShaanxiChina Department of Pathology West China HospitalSichuan UniversityChengduSichuanChina Cancer Center of jinling Hospital Nanjing University of Chinese MedicineNanjingJiangsuChina Department of Pathology The First Affiliated HospitalChina Medical UniversityShenyangLiaoningChina Department of Pathology The 900 Hospital of the Chinese People's Liberation Army Joint Logistics TeamFuzhouFujianChina Department of Pathology The Third Affiliated HospitalSun Yat-Sen UniversityGuangz

Intrahepatic cholangiocarcinoma(iCCA)can originate from the large bile duct group(segment bile ducts and area bile ducts),small bile duct group(septal bile ducts and interlobular bile ducts),and terminal bile duct group(bile ductules and canals of Hering)of the intrahepatic biliary tree,which can be histopathological corresponding to large duct type iCCA,small duct type iCCA and iCCA with ductal plate malformation pattern,and cholangiolocarcinoma,*** challenge in pathological diagnosis of above subtypes of iCCA falls in the distinction of cellular morphologies,tissue structures,growth patterns,invasive behaviors,immunophenotypes,molecular mutations,and surgical *** these reasons,this expert consensus provides nine recommendations as a reference for standardizing and refining the diagnosis of pathological subtypes of iCCA,mainly based on the 5th edition of the World Health Organization Classification of Tumours of the Digestive System.

关键词： Intrahepatic cholangiocarcinoma Pathology Histological type Immunohistochemistry Molecular variation

Incidence and prognosis of olfactory and gustatory dysfunctions related to SARS-CoV-2 Omicron strain infection in China:A national multicenter survey of 35,566 individuals

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 113-120页

作者： Meng-Fan Liu Rui-Xia Ma Xian-Bao Cao hua Zhang shui-Hong Zhou Wei-Hong jiang yan jiang jing-Wu sun Qin-Tai yang Xue-Zhong Li Ya-Nan sun Li Shi Min wang Xi-Cheng Song Fu-Quan Chen Xiao-shu Zhang Hong-Quan Wei shao-Qing Yu Dong-Dong Zhu luo Ba Zhi-Wei Cao Xu-ping Xiao Xin Wei Zhi-Hong Lin Feng-Hong Chen Chun-guang Shan guang-Ke wang jing Ye Shen-Hong Qu Chang-Qing Zhao Zhen-Lin wang hua-Bin Li Feng Liu Xiao-Bo Cui Sheng-Nan Ye Zheng Liu Yu Xu Xiao Cai Wei huang Ru-Xin Zhang Yu-Lin Zhao guo-Dong Yu guang-Gang Shi Mei-ping lu yang Shen Yu-Tong Zhao Jia-Hong Pei shao-Bing Xie Long-Gang Yu Ye-Hai Liu shao-Wei Gu Yu-Cheng yang Lei Cheng jian-Feng liu Graduate School of Beijing University of Chinese Medicine BeijingChina Department of Otorhinolaryngology Head and Neck Surgery China-Japan Friendship HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery The First People's Hospital of YinchuanYinchuanChina Department of Otorhinolaryngology The First People's Hospital of Yunnan ProvinceKunmingChina Department of Otorhinolaryngology The First Affiliated Hospital of Xinjiang Medical UniversityUrumqiChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of Zhejiang University School of MedicineHangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Xiangya Hospital Central South UniversityChangshaChina Department of Otorhinolaryngology Head and Neck Surgery The Affiliated Hospital of Qingdao UniversityQingdaoChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of USTCHefeiChina Department of Otorhinolaryngology Head and Neck Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouChina Department of Otorhinolaryngology Head and Neck Surgery Qilu Hospital of Shandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery The Second Affiliated Hospital of Harbin Medical UniversityHarbinChina Department of Otolaryngology The Second Hospital of Shandong UniversityShandong UniversityJinanChina Department of Otorhinolaryngology Head and Neck Surgery Peking University People's HospitalBeijingChina Department of Otorhinolaryngology Head and Neck Surgery Yantai Yuhuangding HospitalQingdao UniversityYantaiChina Department of Otorhinolaryngology Head and Neck Surgery Xijing HospitalThe Fourth Military Medical UniversityXi'anChina Gansu Provincial Center for Disease Control and Prevention LanzhouChina Department of Otorhinolaryngology Head and Neck Surgery The First Affiliated Hospital of China Medical UniversityShenyangChina Department of Otorhinolaryngology Head and Neck Surgery Tongji Hospit

Objective:This cross-sectional study aimed to determine the epidemiology of olfactory and gustatory dysfunctions related to COVID-19 in ***:This study was conducted by 45 tertiary Grade-A hospitals in *** and offline questionnaire data were obtained from patients infected with COVID-19 between December 28,2022,and February 21,*** collected information included basic demographics,medical history,smoking and drinking history,vaccination history,changes in olfactory and gustatory functions before and after infection,and other postinfection symptoms,as well as the duration and improvement status of olfactory and gustatory ***:Complete questionnaires were obtained from 35,566 *** overall incidence of olfactory and taste dysfunction was 67.75%.Being female or being a cigarette smoker increased the likelihood of developing olfactory and taste *** received four doses of the vaccine or having good oral health or being a alcohol drinker decreased the risk of such *** infection,the average olfactory and taste VAS scores were 8.41 and 8.51,respectively;after infection,they decreased to 3.69 and 4.29 and recovered to 5.83 and 6.55 by the time of the *** median duration of dysosmia and dysgeusia was 15 and 12 days,respectively,with 0.5%of patients having symptoms lasting for more than 28 *** overall self-reported improvement rate was 59.16%.Recovery was higher in males,never smokers,those who received two or three vaccine doses,and those that had never experienced dental health issues,or chronic accompanying ***:The incidence of dysosmia and dysgeusia following infection with the SARS-CoV-2 virus is high in *** and prognosis are influenced by several factors,including sex,SARS-CoV-2 vaccination,history of head-facial trauma,nasal and oral health status,smoking and drinking history,and the persistence of accompanying symptoms.

关键词： epidemiologic studies incidence olfactory disorders prognosis SARS-CoV-2 taste disorders

Consensus statement on layout and delivery of automatic external defibrillator in China

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Journal of Hainan Medical University 2020年第15期26卷 18-23页

作者： Yu Cao Song Chen yan-Fen Chai Xiao-Hui Chen Yu-guo Chen shao-Wen Cheng Wen-Wei Cheng Bang-Han Ding yang Deng Jie Fu Bang-jiang Fang Mai-Ying Fan Li Gui ping Gong Wei guo shu-Bin guo Liang huang Ji-Yuan Han Zhong Ji Xian-Fei Ji Xin-Cai Ji Hong-Xu jin Xin-Jun jiang wang-Xiang jiang Jia-Liang Liu Xiao-Ran Liu Zhi Liu Chuan-Zhu Lv Feng lu Tan-Shi Li Xin Li Yong Li Shang-lun Li Shuang-Ming Li Xiao-Gang Li Bao-Jun Li Pei-Wu Li Chun-Sheng Li Zhi-Jun Li Chang-luo Li Xiang-Min Li Yin-ping Li Zong-Jun lu Zu-Xun lu Zhong-Qiu lu Zhi-Qian luo Xiao-Xing Liao jian-Bo Lei Tao Ma Yu Ma Yue-Feng Ma Qing-Bian Ma Lin-Hao Ma Jun-Qi Ma Shi-Nan Nie Jie-Miao Ou-yang Peng Peng Qiao Pei shu-Ming Pan guo-Zhong Qing Li-Jie Qin Wu-Ying Qiao Fei shao Wei Song Xing-Yue Song Zhen-Ju Song Rong-Ju sun De-Ya Shang Du-Juan Sha Gui-Lan Tao guo-Gang Tian Ying-ping Tian jian-guang Tian Chao-yang Tong Zi-Ren Tang Meng-Xiong Tang guo-ping Wu Zhi wan Tao wang Xin wang Peng wang Zhong wang Tong wang Ri-Xing wang Yi-Xin wang Xiao-Dan wang Ling Wu Wei Wei hua Xiang Feng Xu Jun Xu Jie Xu Miao-Rong Xie shuo-Gui Xu Tie Xu Feng Yu Wen Yi Li-Shan yang Shi-Jiao yan jin-jian Yao Shou-Chun yan Xue-Zhong Yu Xian-Zhi Ye Xian-Liang yan Fu-Bing Zhou Rong-Bin Zhou Ming Zhou Qiang Zhou jin Zhou ping Zhou Chang-Ju Zhu hua-Dong Zhu Ji-Hong Zhu Hong Zhang Mao Zhang hua Zhang Na Zhang guo-Qiang Zhang guo-Xiu Zhang jin-Song Zhang Wen-Wu Zhang Wen-Zhong Zhang jian-Feng Zhang Yi-Min Zhu Jun Zeng Yuan Zheng Zhi-Jie Zheng Shen Zhao yan Zhao Min Zhao Bin Zhao Xiao-Dong Zhao Xiao-jing Zhao Hong-Ke Zeng Sheng-Qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi Junsong Cang guofu Cao jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen guoming Chen hua-Xing Chen Huirun Chen jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen shao-Long Chen shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP jinR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

2017年中国ICU患者营养治疗实施状况横断面调查

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解放军医学杂志 2019年第5期44卷 388-393页

作者：邢娟章仲恒柯路周晶秦秉玉梁宏开陈晓梅刘文明刘忠民艾宇航王迪芬王秋卉周青山张福森钱克俭蒋东坡臧彬黎毅敏黄晓波曲彦谢颖光许东琳邹志强郑祥德刘建波郭丰梁亚风孙强高红梅刘阳常平程爱斌杨荣利么改琦孙昀王晓蓉张怡熊旭明于健孙荣青李志伟袁世荧宋云林高培阳刘海燕张朝辉吴允孚马标郭强山峰杨明施李海玲李圆菲鲁卫华王磊钱传云王智勇林建东张汝敏万鹏彭志勇龚裕强黄林喜伍国宝孙洁邓义军师东武周立新周发春石秦东郭晓东刘雪燕武卫东孟祥忠李连弟陈炜炜李树生万献尧曹志新张安古利明陈炜吴京兰周丽华张震环翁以炳封永顺杨春丽冯永健赵素民佟飞郝东韩辉付宝才巩传勇李志平胡琨琳寇秋野张晗刘洁樊楚明周新陈秀梅孙俊丽周学军宋斌孙诚赵丽芸董兴鲁张琳琳佟大为潘志国蔡常洁王东浩董英俊龚园其吴志松孟新科王平李维勤南京医科大学金陵临床医学院南京210002 无锡人民医院江苏无锡214001 北京市密云区医院北京101500 洛阳市中心医院河南洛阳471009 北京市怀柔区第一医院北京101400 陆军总医院北京100700 广东省人民医院广州510080 广东省第二中医院广州510095 北京中医医院北京100010 安徽省立医院西院区合肥230001 沈阳市第一人民医院沈阳110041 南部战区总医院广州510050 湖北省人民医院武汉430060 中山大学附属第一医院广州510080 天津市肿瘤医院天津300060 山西省肿瘤医院太原030000 南昌大学第二附属医院南昌330006 北京中医药大学东方医院北京100029 深圳第二人民医院广东深圳100730 成都市第五人民医院成都611130 泰安市中心医院山东泰安271000 南昌大学第一附属医院南昌330006 陆军军医大学大坪医院重庆400042 中国医科大学附属第二医院沈阳110004 广州医科大学附属第一医院广州510120 四川省人民医院成都610072 青岛市立医院青岛266071 济宁市第一人民医院山东济宁272000 浙江大学医学院附属邵逸夫医院杭州310016 广州市第一人民医院广州510000 福建医科大学附属协和医院福州350001 达州市中心医院四川达州635000 内蒙古自治区人民医院呼和浩特010017 烟台毓璜顶医院山东烟台264000 天津市人民医院天津300000 天津市第一中心医院天津300192 唐山市工人医院河北唐山063000 南方医科大学珠江医院广州510515 华北理工大学附属医院河北唐山063210 河南省人民医院郑州450003 大连市中心医院辽宁大连116033 北京大学第三医院北京100083 安徽医科大学第二附属医院合肥230601 温州医科大学附属第一医院浙江温州325000 陕西省人民医院西安710068 广州医科大学附属第二医院广州510120 大连医科大学附属第二医院辽宁大连116011 郑州大学第一附属医院郑州450052 昆明市第一人民医院昆明650011 华中科技大学同济医学院附属协和医院武汉430030 中山市人民医院广东中山528403 新疆医科大学第一附属医院乌鲁木齐830054 成都中医药大学附属医院成都610075 安徽医科大学第一附属医院合肥230032 宜昌市中心人民医院湖北宜昌443003 苏州市立医院东区江苏苏州215008 济宁医学院附属医院山东济宁272000 苏州大学附属第一人民医院江苏苏州215006 青岛大学医学院附属医院东院区山东青岛266071 中南大学湘雅三医院长沙410013 海军第971医院山东青岛266073 山东大学齐鲁医院济南250012 长沙市中心医院长沙410000 皖南医学院弋矶山医院安徽芜湖241002 山西医科大学第一医院太原030001 昆明医科大学第一附属医院昆明650032 河北医科大学第三医院石家庄050017 福建医科大学附属第一医院福州350004 淄博市中心医院山东淄博100085 宜昌市第一人民医院湖北宜昌443003 武汉大学中南医院武汉430071 温州医科大学附属第二医院浙江温州325035 常州市第二人民医院江苏常州213003 汕头大学医学院第一附属医院广东汕头515041 中南大学湘雅二医院长沙410013 云南省第二人民医院昆明650021 盐城市第一人民医院江苏盐城224006 山西省人民医院太原030012 佛山市第一人民医院广东佛山528000 重庆医科大学附属第一医院重庆400016 西安交通大学第一附属医院西安710061 解放军总医院第三医学中心北京100039 深圳市人民医院广东深圳518001 吉林大学第一医院长春130031 山西医学科学院山西大医院太原030032 解放军第254医院天津300142 青岛大学附属医院山东青岛266003 临海市第一人民医院浙江台州317000 华中科技大学同济医学院附属同济医院武汉430030 大连医科大学附属第一医院辽宁大连116011 北京朝阳医院京西院区北京100043 重庆医科大学附属第二医院重庆400016 玉溪市人民医院云南玉溪653405 首都医科大学世纪坛医院北京100036 中南大学湘雅医院长沙410013 深圳市南山人民医院广东深圳518067 内蒙古医科大学附属医院呼和浩特010050 南京明基医院南京210019 首都医科大学附属北京潞河医院北京101149 京煤集团总医院北京102300 江西省人民医院南昌330006 暨南大学附属第一医院广

目的了解国内ICU收治患者的营养治疗实施状况。方法对国内116家医院的118个ICU内的患者进行营养治疗实施状况的横断面调查。以2017年4月26日0时所有在ICU内治疗的患者为调查对象,收集患者基本信息、2017年4月25日(即调查日)的营养实施... 详细信息

目的了解国内ICU收治患者的营养治疗实施状况。方法对国内116家医院的118个ICU内的患者进行营养治疗实施状况的横断面调查。以2017年4月26日0时所有在ICU内治疗的患者为调查对象,收集患者基本信息、2017年4月25日(即调查日)的营养实施和胃肠道耐受情况,以及患者的28 d临床转归情况。结果调查共收集病例1953例,女631例(32.4%),男1306例(66.9%),缺失16例(0.7%);年龄(64.1±19.3)岁(1950例)。患者GCS、SOFA和APACHEⅡ评分分别为(10.76±4.35)分(1749例)、(5.65±3.52)分(1783例)、(17.14±7.31)分(1792例)。28 d临床转归存活1483例(75.9%),死亡312例(16.0%),失访+缺失158例(8.1%)。除身高和体重(P=0.000)外,男性与女性患者在年龄、病情严重程度及28 d临床转归等方面差异均无统计学意义。1953例患者中,胃肠功能评估为正常或轻度损害占73.7%(1440例),中-重度损害占10.8%(210例),衰竭占1.7%(33例),13.2%(258例)的患者未做评估。截至调查日,69.4%(1356例)的患者已启动肠内营养(EN),36.4%(711例)的患者已启动肠外营养(PN)。调查日有营养摄入的患者1720例(88.1%)。1953例患者中明确有恶心、呕吐反流、误吸、腹痛、腹胀、腹泻(大便次数≥3次/d且量≥500 ml/d)等胃肠道不耐受表现的分别占总人数的4.8%(93例)、5.4%(105例)、0.9%(17例)、8.7%(170例)、27.5%(538例)和4.3%(84例)。在1270例使用EN的病例中,明确存在恶心、呕吐反流、误吸、腹痛、腹胀、腹泻等不耐受症状的分别占3.2%(40例)、4.3%(54例)、0.8%(10例)、4.4%(56例)、26.9%(341例)和5.4%(69例)。入ICU后24 h内开始EN治疗的患者占22.4%(437/1953),48 h内开始的占38.6%(754/1953),72 h内开始的占46.6%(911/1953)。患者入ICU后3 d总热卡(EN+PN非蛋白热卡)达标率为12.9%(78/607),7 d总热卡达标率为18.7%(189/1010),14 d总热卡的达标率为23.0%(305/1325)。入ICU后3、7、14 dEN达标率分别为9.9%(60/607)、15.0%(151/1010)和18.6%(246/1325)。结论目前我国ICU内的绝大多数患者均接受了营养治疗,其中EN的使用率明显高于PN;但EN的开始时间和达标情况仍不理想,且实施营养治疗时未能体现个体化差异,营养治疗的细节仍需要提高。

关键词：横断面研究肠内营养重症监护病房胃肠道耐受性营养达标率

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注射用丹参多酚酸盐的临床应用综合评价

中国药学杂志 2021年第6期56卷 507-514页

作者：韩晟赵熙子史录文林丽开李大魁陈凯先宣利江马传江马海英方唯一王丽霞文爱东付秀娟左燕刘小玲刘向红刘国强朱珠陈万生陈维红吴方建吴玉波吴晖张伟张毕奎林慧周国华欧阳荣胡元会姜明燕赵春景贾乐川晋月萍唐洪梅曹俊岭梁春商洪才董占军董吁钢翟所迪北京大学医药管理国际研究中心北京100191 武汉大学中南医院武汉大学医院管理研究所武汉430071 北京协和医院北京100730 中国科学院上海药物研究所上海201203 山东中医药大学附属医院济南250014 中国医科大学附属第四医院沈阳110000 复旦大学附属华东医院上海200030 中国中医科学院广安门医院北京100053 中国人民解放军空军军医大学第一附属医院西安710032 吉林大学第二医院长春130041 陕西省人民医院西安710068 内蒙古自治区人民医院呼和浩特010017 山东大学齐鲁医院济南250012 河北医科大学第三医院石家庄050051 海军军医大学第二附属医院上海200003 山西白求恩医院(山西医学科学院) 太原030032 长江航运总医院武汉430015 哈尔滨医科大学附属第四医院哈尔滨150001 昆明医科大学第一附属医院昆明650032 河南省人民医院郑州450003 中南大学湘雅二医院长沙410011 海南省药学会海口570102 南京大学医学院附属金陵医院南京210000 湖南中医药大学第一附属医院长沙410007 中国医科大学附属第一医院沈阳110001 重庆医科大学附属第二医院重庆400010 宁夏医科大学总医院银川750004 山西医科大学第一医院太原030001 广州中医药大学第一附属医院广州510405 北京中医药大学东方医院北京100078 北京中医药大学东直门医院北京100007 河北省人民医院石家庄050051 中山大学附属第一医院广州510080 北京大学第三医院北京100191

目的以注射用丹参多酚酸盐为例,探索中药注射剂临床应用的综合评价方法,为今后相关工作的开展和完善提供参考。方法通过文献检索和获取相关文献资料,从有效性、安全性、经济性、顺应性和标签信息等方面对注射用丹参多酚酸盐进行系统综... 详细信息

目的以注射用丹参多酚酸盐为例,探索中药注射剂临床应用的综合评价方法,为今后相关工作的开展和完善提供参考。方法通过文献检索和获取相关文献资料,从有效性、安全性、经济性、顺应性和标签信息等方面对注射用丹参多酚酸盐进行系统综合评价。结果除说明书适应证外,丹参多酚酸盐在心血管疾病、脑血管疾病等多种超说明书适应证中都存在具有一定质量的临床研究证据;在安全性、经济性方面的文献证据较为丰富。结论注射用丹参多酚酸盐在有效性、安全性及经济性等方面的临床研究证据较多,且具有一定的体系。但作为一个临床应用大品种,该药依然需要在一些方面做出更多的研究努力。

关键词：丹参酚酸B镁药品综合评价中药注射剂有效性安全性