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Low Ca diet leads to increased Ca retention by changing the gut flora and ileal pH value in laying hens

Animal Nutrition 2023年第2期13卷 270-281页

作者： sha jiang Xinyu Zou Miao Mao Mi Zhang Wenjun Tu Meilan Jin Joint International Research Laboratory of Animal Health and Animal Food Safety College of Veterinary MedicineSouthwest UniversityChongqing400715China Immunology Research Center Medical Research InstituteSouthwest UniversityChongqing402460China Laboratory Animal Center Southwest UniversityChongqing400715China

Osteoporosis is a common degenerative metabolic bone disease in caged laying *** egg production mobilizing large amounts of Ca from bone for eggshell formation,consequently leading to Ca deficiency,has been recognized as a critical factor causing osteoporosis in commercial laying *** aim of this study was to examine the effect of Ca deficiency on the function of the gut microbiotaebone axis and related egg production traits and bone health in laying ***-four 48-week-old laying hens were fed a control diet(Control,3.72%)or a low Ca diet(LC,2.04%)for 60 d(n=12).Compared to the Control hens,the LC hens had higher levels of alkaline phosphatase and tartrate resistant acid phosphatase(P<0.05)with lower bone strength,eggshell thickness,and eggshell strength(P<0.05).In addition,the LC hens had higher plasma estradiol concentrations,while having lower concentrations of interleukin-1(IL-1)and *** LC hens also had a lower pH value in the ileum with an increased Ca *** principal co-ordinates analysis showed significantly separate cecal microbiota populations between the Control and LC *** Prevotellaceae_UCG-001,Subdoligranulum,Peptococcus,and Eubacterium_hallii_group(P<0.05)were higher,while the CHKC1001 and Sutterella(P<0.05)were lower at the genus level in the LC *** addition,Prevotellaceae_UCG-001,Subdoligranulum and Eubacter-ium_hallii_group had a negative correlation,while Sutterella was positively correlated with ileal pH *** transcriptome analysis revealed that the low Ca diet caused 20 and 31 genes to be signifi-cantly up-and down-regulated,*** gene expressions of cystic fibrosis transmembrane conductance regulator,solute carrier family 26 member 3 of the anion exchangers,and mitogen-activated protein kinase 12 of pro-inflammatory factors were lower in the LC birds,which was corre-lated with the lower ileal pH *** results suggest that the hens with low Ca diet-induced osteoporosis have an incr

关键词： Low Ca diet Ca retention Microbiota Transcriptional profiling Hen

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张伯苓的学校体育思想及其对小学体育的启示

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当代教研论丛 2024年第8期10卷 54-57页

作者：沈建华陈佳伟蒋莎杭州师范大学经亨颐教育学院浙江杭州311121 杭州市丁荷小学浙江杭州310000 浙江师范大学附属丁蕙实验小学浙江杭州310000

学校体育是体育强国建设的基础性工程,对教育强国建设、健康中国建设和实现中华民族伟大复兴的中国梦具有重要意义。作为一位杰出的爱国教育者,张伯苓对于体育教育的杰出成就使得他在这一领域具有深远的影响力,他的体育教育观念对体育... 详细信息

学校体育是体育强国建设的基础性工程,对教育强国建设、健康中国建设和实现中华民族伟大复兴的中国梦具有重要意义。作为一位杰出的爱国教育者,张伯苓对于体育教育的杰出成就使得他在这一领域具有深远的影响力,他的体育教育观念对体育教育的发展具有重要的指引作用,同时也对小学体育教育实践具有宝贵的借鉴价值。

关键词：张伯苓体育教育思想小学体育

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PIV EXPERIMENTAL RESEARCH OF INSTANTANEOUS FLOW CHARACTERISTICS OF CIRCULAR ORIFICE SYNTHETIC JET

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Journal of Hydrodynamics 2007年第4期19卷 453-458页

作者： XU Jing-lei sha jiang LIN Chun-feng ZHANG Kun-yuan School of Energy and Power Engineering Nanjing University of Aeronautics and Astronautics Nanjing 210016 China

The instantaneous flow characteristics of circular orifice synthetic jet was experimentally studied by a phase-locked Particle Image Velocimetry （PIV） system. The instantaneous flowfields, including the forming, developing and breaking down of the vortex for the jet were clearly shown by the PIV experimental results. As the basis of the study of the instantaneous flow, 36 images were taken and phase-averaged for each condition. The PIV experiment was mainly focused on the time evolution of the vortex pairs formed in the push cycle, the saddle point existing in the suck cycle, the variation of the centerline velocity in the whole cycle and the cross-stream velocity profiles and their self-similarity. Finally, the orifice depth was changed from 1.5 mm to 2 mm and 3.5 mm in order to study the effect of different orifice depths on the flow structure, which shows that at all stream wise sections, the peak of the mass flux and momentum flux increases as the orifice depth increases. Furthermore, the nondimensional distance of the mass flux from the exit is the maximum, while the nondimensional distance of the centerline velocity peak from the exit is the minimum, and nondimensional distance of the momentum flux from the exit section is between them.

关键词： circular synthetic jet Particle Image Velocimetry (PIV) phase-locked

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Role of GA_3,GA_4 and Uniconazole-P in Controlling Gravitropism and Tension Wood Formation in Fraxinus mandshurica Rupr. var. japonica Maxim. Seedlings

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Journal of Integrative Plant Biology 2008年第1期50卷 19-28页

作者： sha jiang Ke Xu Yong-Zhou Wang Yan-Ping Ren Song Gu College of Life Sciences Nankai University Tianjin 300071 China

GA3 and GA4 （gibberellins） play an important role in controlling gravitropism and tension wood formation in woody angiosperms. In order to improve our understanding of the role of GA3 and GA4 on xylem cell formation and the G-layer, we studied the effect of GA3 and GA4 and uniconazole-P, which is an inhibitor of GA biosynthesis, on tension wood formation by gravity in Fraxinus mandshurica Rupr. var. japonica Maxim. seedlings. Forty seedlings were divided into two groups; one group was placed upright and the other tilted. Each group was further divided into four sub-groups subjected to the following treatments： 3.43 x 10-9 lunol acetone as control, 5.78 x 10-8 lunol gibberellic acid （GA3）, 6.21 x 10-8 lunol GA4, and 6.86 x 10-8 lunol uniconazole-P. During the experimental period, GAs-treated seedlings exhibited negative gravitropism, whereas application of uniconazole-P inhibited negative gravitropic stem bending. GA3 and GA4 promoted wood fibers that possessed a gelatinous layer on the upper side, whereas uniconazole-P inhibited wood formation but did not inhibit the differentiation of the gelatinous layer in wood fibers on the upper side. These results suggest that：（i） both the formation of gelatinous fibers and the quantity of xylem production are important for the negative gravitropism in horizontally-positioned seedlings; （ii） GA3 and GA4 affect wood production more than differentiation of the gelatinous layer in wood fibers; G-layer development may be regulated by other hormones via the indirect-role of GA3 and GA4 in horizontally-positioned F. mandshurica seedlings rather than the direct effect of GAs; and （iii） the mechanism for upward wood stem bending is different to the newly developed shoot bending in reaction to gravity in this species.

关键词： GA3, GA4 gelatinous layer gravitropism Fraxinus mandshurica var. japonica Maxim. seedlings tension wood formation uniconazole-P.

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Evapotranspiration and Its Energy Exchange in Alpine Meadow Ecosystem on the Qinghai-Tibetan Plateau

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Journal of Integrative Agriculture 2013年第8期12卷 1396-1401页

作者： LI Jie jiang sha WANG Bin jiang Wei-wei TANG Yan-hong DU Ming-yuan GU Song College of Life Science Nankai University National Institute for Environmental Studies National Institute for Agro-Environmental Sciences

To understand the water and energy exchange on the Qinghai-Tibetan Plateau, we explored the characteristics of evapotranspiration （ET） and energy fluxes from 2002 to 2005 over a Kobresia meadow ecosystem using the eddy covariance method. The ratio of annual ET to precipitation （P） of meadow ecosystem was about 60%, but varied greatly with the change of season from summer to winter. The annual ET/P in meadow was lower than that in shrub, steppe and wetland ecosystems of this plateau. The incident solar radiation （Rs） received by the meadow was obviously higher than that of lowland in the same latitude; however the ratio of net radiation （Rn） to Rs with average annual value of 0.44 was significantly lower than that in the same latitude. The average annual ET was about 390 mm for 2002-2005, of which more than 80% occurred in growing season from May to September. The energy consumed on the ET was about 44% of net radiation in growing season, which was lower than that of shrub, steppe and wetland on this plateau. This study demonstrates that the Kobresia meadow may prevent the excessive water loss through evapotranspiration from the ecosystem into the atmosphere in comparison to the shrub, steppe and wetland ecosystems of the Qinghai-Tibetan Plateau.

关键词： eddy covariance evapotranspiration net radiation precipitation Qinghai-Tibetan Plateau

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社区获得性重症肺炎患者死亡风险因素探讨

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医学信息 2024年第15期37卷 27-32页

作者：李卫东沈玄洋张美琪谭文涛将莎莎冯尧川北医学院附属医院急诊医学科

目的探讨社区获得性重症肺炎死亡相关危险因素，为进一步优化社区获得性重症肺炎治疗提供理论依据。方法回顾性收集2020年1月-2022年12月川北医学院附属医院住院的社区获得性重症肺炎患者资料，并将纳入的病例分为存活组与死亡组。通... 详细信息

目的探讨社区获得性重症肺炎死亡相关危险因素，为进一步优化社区获得性重症肺炎治疗提供理论依据。方法回顾性收集2020年1月-2022年12月川北医学院附属医院住院的社区获得性重症肺炎患者资料，并将纳入的病例分为存活组与死亡组。通过多因素Logistic回归分析死亡相关危险因素，联合实验室检查指标绘制受试者工作特征曲线(ROC曲线)分析各指标对社区获得性重症肺炎的预测价值。结果共收集了230例社区获得性重症肺炎病例，其中死亡组78例(33.91%)，存活组152例(66.09%)。两组年龄、性别、是否合并高血压、是否合并慢性阻塞性肺疾病比较，差异无统计学意义(P>0.05)；两组实验室指标中C反应蛋白(CRP)、降钙素原(PCT)、白介素6(IL-6)、N末端B型脑钠肽前体(NT-proBNP)、丙氨酸氨基转移酶(ALT)、肌钙蛋白T(cTnT)、凝血酶原时间(PT)、乳酸(LAC)、D-二聚体(D-Dimer)和铁蛋白(Ferritin)比较，差异有统计学意义(P<0.05);LAC、IL-6、铁蛋白联合预测死亡风险的截断值0.174，约登指数0.858，灵敏度92.20%，特异度93.60%，其ROC曲线下面积(AUC)为0.968[95%CI(0.94,0.996)]。结论 LAC、IL-6、铁蛋白增高均是社区获得性重症肺炎死亡独立危险因素，四者联合对社区获得性重症肺炎死亡具有更高的预测价值。

关键词：社区获得性重症肺炎危险因素预测价值死亡

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国内预制菜标准现状分析

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食品安全导刊 2024年第16期 19-22页

作者：温欣宋佳璇姜莎张慧高智慧内蒙古自治区市场监督管理审评查验中心内蒙古呼和浩特010010

随着生活节奏加快,预制菜受到越来越多消费者青睐,预制菜产业也迅猛扩张。为强化预制菜食品安全监管,促进预制菜行业有序发展,国家和地方陆续出台了相关政策法规,行业与企业相继制定了预制菜系列标准。本文对国内已发布的预制菜相关标... 详细信息

随着生活节奏加快,预制菜受到越来越多消费者青睐,预制菜产业也迅猛扩张。为强化预制菜食品安全监管,促进预制菜行业有序发展,国家和地方陆续出台了相关政策法规,行业与企业相继制定了预制菜系列标准。本文对国内已发布的预制菜相关标准进行梳理,为下一步完善预制菜食品标准体系工作提供依据。

关键词：预制菜标准现状

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Edge assisted epitaxy of CsPbBr_(3)nanoplates on Bi_(2)O_(2)Se nanosheets for enhanced photoresponse

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Chinese Physics B 2022年第4期31卷 693-699页

作者： Haotian jiang Xing Xu Chao Fan Beibei Dai Zhuodong Qi sha jiang Mengqiu Cai Qinglin Zhang Key Laboratory for Micro-/Nano-Optoelectronic Devices of Ministry of Education School of Physics and ElectronicsHunan UniversityChangsha 410082China

Bi_(2)O_(2)Se has been proved to be a promising candidate for electronic and optoelectronic devices due to their unique physical ***,it is still a great challenge to construct the heterostructures with direct epitaxy of hetero semiconductor materials on Bi_(2)O_(2)Se ***,a two-step chemical vapor deposition(CVD)route was used to directly grow the CsPbBr_(3)nanoplate-Bi_(2)O_(2)Se nanosheet hetero *** CsPbBr_(3)nanoplates were selectively grown on the Bi_(2)O_(2)Se nanosheet along the edges,where the dangling bonds provide the nucleation *** epitaxial relationships between CsPbBr3 and Bi_(2)O_(2)Se were determined as[200]_(Bi_(2)O_(2)Se)‖[110]_(CsPbBr_(3))and[110]_(Bi_(2)O_(2)Se)‖[200]_(CsPbBr_(3))by transmission electron microscopy *** photoluminescence(PL)results reveal that the formation of heterostructures results in the remarkable PL quenching due to the type-Ⅰband arrangement at CsPbBr_(3)/Bi_(2)O_(2)Se interface,which was confirmed by ultraviolet photoelectron spectroscopy(UPS)and Kelvin probe measurements,and makes the photogenerated carriers transfer from CsPbBr_(3)to Bi_(2)O_(2)***,the photodetectors based on the heterostructures exhibit a 4-time increase in the responsivity compared to those based on the pristine Bi_(2)O_(2)Se sheets,and the fast rise and decay time in *** results indicate that the direct epitaxy of the CsPbBr_(3)plates on the Bi_(2)O_(2)Se sheet may improve the optoelectronic performance of Bi_(2)O_(2)Se based devices.

关键词： Bi_(2)O_(2)Se heterostructures photogenerated carriers photoresponse

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Influence of ganglioside combined with methylprednisolone sodium succinate on efficacy and neurological function in patients with acute myelitis

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World Journal of Clinical Cases 2023年第33期11卷 7972-7979页

作者： Yu-Fei Sun Li-Li Liu sha-sha jiang Xian-Juan Zhang Feng-Jun Liu Wan-Ming Zhang Department of Special Medicine Basic Medical College of Qingdao UniversityQingdao 266071Shandong ProvinceChina Department of Medical Microbiology Basic Medical College of Qingdao UniversityQingdao 266075Shandong ProvinceChina Department of Clinical Laboratory The Affiliated Hospital of Qingdao UniversityQingdao 266000Shandong ProvinceChina Department of Special Medicine School of Basic MedicineQingdao UniversityQingdao 266000Shandong ProvinceChina

BACKGROUND Acute myelitis(AM)can lead to sudden sensory,motor and autonomic nervous dysfunction,which negatively affects their daily activities and quality of life,so it is necessary to explore optimization from a therapeutic perspective to curb the progression of the *** To investigate the effect of ganglioside(GM)combined with methylprednisolone sodium succinate(MPSS)on the curative effect and neurological function of patients with *** First,we selected 108 AM patients visited between September 2019 and September 2022 and grouped them based on treatment modality,with 52 patients receiving gamma globulin(GG)+MPSS and 56 patients receiving GM+MPSS,assigned to the control group(Con)and observation group(Obs),*** therapeutic effect,neurological function(sensory and motor function scores),adverse events(AEs),recovery(time to sphincter function recovery,time to limb muscle strength recovery above grade 2,and time to ambulation),inflammatory factors(IFs)[interleukin(IL)-6,C-reactive protein(CRP),and tumor necrosis factor(TNF)-α]and other data of the two groups were collected for evaluation and *** The Obs had:(1)A significantly higher response rate of treatment than the Con;(2)Higher scores of sensory and motor functions after treatment that were higher than the baseline(before treatment)and higher than the Con levels;(3)Lower incidence rates of skin rash,gastrointestinal discomfort,dyslipidemia,osteoporosis and other AEs;(4)Faster posttreatment recovery of sphincter function,limb muscle strength and ambulation;and(5)Markedly lower posttreatment IL-6,CRP and TNF-αlevels than the baseline and the Con *** From the above,it can be seen that GM+MPSS is highly effective in treating AM,with a favorable safety profile comparable to that of GG+*** can significantly improve patients’neurological function,speed up their recovery and inhibit serum IFs.

关键词： Ganglioside Methylprednisolone sodium succinate Acute myelitis Therapeutic effect Neurological function

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基于硒强化因子赋型于食品载体的研究进展

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现代食品 2024年第5期30卷 17-21,29页

作者：白雨石杨晶琦李皎月钟利敏周彦如江沙姜鹏飞大连工业大学食品学院国家海洋食品工程技术研究中心辽宁大连116034 大连市甘井子区市场监管事务服务中心辽宁大连116034 赣州市全标生物科技有限公司江西赣州341100 江西广来健康产业有限公司江西樟树331200 广东伙伴智能装备有限公司广东中山528451

硒元素在人体内含量较少,但作为人体内必需的微量元素之一,却起到了非常重要的作用。食物是人类获取硒元素的重要途径之一,其中因有机硒的安全剂量范围更广、生物利用率更高,适合作为食品的载体对人体进行硒元素补充。纳米硒可以通过与... 详细信息

硒元素在人体内含量较少,但作为人体内必需的微量元素之一,却起到了非常重要的作用。食物是人类获取硒元素的重要途径之一,其中因有机硒的安全剂量范围更广、生物利用率更高,适合作为食品的载体对人体进行硒元素补充。纳米硒可以通过与其他物质进行结合,形成具有抗炎症、预防肾病和抗癌等功效的纳米粒子。本文主要是针对硒强化因子在食品载体方面的应用进行研究归纳,以期为食品为载体进行硒元素强化提供理论基础和指导。

关键词：硒纳米硒食品载体补充效果药物协同

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