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Influencing Factors and Prediction of Risk of Returning to Ecological Poverty in Liupan Mountain Region,China

Chinese Geographical Science 2024年第3期34卷 420-435页

作者： CUI Yunxia LIU Xiaopeng jiang chunmei TIAN Rujun NIU Qingrui School of Geography and Planning Ningxia UniversityYinchuan 750021China Key Laboratory(China-Arab)of Resource Evaluation and Environmental Regulation of Arid Region in Ningxia Yinchuan 750021China

China has resolved its overall regional poverty in 2020 by attaining moderate societal *** country has entered a new development stage designed to achieve its second centenary ***,ecological fragility and risk susceptibility have increased the risk of returning to ecological *** this paper,the Liupan Mountain Region of China was used as a case study,and the counties were used as the scale to reveal the spatiotempora differentiation and influcing factors of the risk of returning to poverty in study *** indicator data for returning to ecological poverty from 2011-2020 were collected and summarized in three dimensions:ecological,economic and *** autoregressive integrated moving average model(ARIMA)time series and exponential smoothing method(ES)were used to predict the multidimensional indicators of returning to ecological poverty for 61 counties(districts)in the Liupan Mountain Region for *** back propagation neural network(BPNN)and geographic information system(GIS)were used to generate the spatial distribution and time variation for the index of the risk of returning to ecological poverty(RREP index).The results show that 1)ecological factors were the main factors in the risk of returning to ecological poverty in Liupan Mountain Region.2)The RREP index for the 61 counties(districts)exhibited a downward trend from *** RREP index declined more in medium-and high-risk areas than in low-risk *** 2021 to 2025,the RREP index exhibited a slight downward *** 2026 to2030,the RREP index was expected to decline faster,especially from 2029-2030.3)Based on the RREP index,it can be roughly divided into three types,namely,the high-risk areas,the medium-risk areas,and the low-risk *** natural resource conditions in lowrisk areas of returning to ecological poverty,were better than those in medium-and high-risk areas.

关键词： risk of returning to ecological poverty autoregressive integrated moving average model(ARIMA) exponential smoothing model back propagation neural network(BPNN) Liupan Mountain Region,China

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Plastid engineering with an efficient RNAi delivery system based on bacteriophage MS2 virus-like particles enhances plant resistance to cotton bollworm

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Molecular Plant 2024年第7期17卷 987-989页

作者： chunmei jiang Jinqiu Fu Fujun Li Kai Xia Shengchun Li Ling Chang Ralph Bock jiang Zhang State Key Laboratory of Biocatalysis and Enzyme Engineering School of Life SciencesHubei Hongshan LaboratoryHubei UniversityWuhan 430062China Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyMinistry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen518000China Max-Planck-Institut fur Molekulare Pflanzenphysiologie Am Muhlenberg 114476Potsdam-GolmGermany

Dear Editor,RNA-based pesticides are approaching the market,offering great potential to control agricultural pests such as the coleopteran insect Diabrotica virgifera virgifera(Head et al.,2017).However,application to lepidopteran pests has been hampered by their inconsistent response to RNA interference(RNAi).As a notorious lepidoptera pest,Helicoverpa armigera feeds on over 300 species of host plants(Fu et al.,2022).Although transgenicplants expressingdouble-stranded RNAs or microRNAs that target essential insect genes can inhibit the growth of larvae,complete protection of the plants and efficient killing of this insect have not been achieved(Bally et al.,2020;Chung et al.,2021;Li et al.,2023).The relatively low RNAi efficiency in lepidopterans is mainly attributable to the degradation and intracellular sequestration of double-stranded RNA(Shukla et al.,2016;Zhu and Palli,2020).To overcome these obstacles and improve RNAi efficiency in ***,we attempted to deliver RNAi molecules using a bacteriophage MS2 virus-like particle(VLP)-based delivery system(Wang et al.,2016).

关键词： overcome offering approaching

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Study on the micro-region structure and properties of two dithienothiophene-dicarboxylic acids

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Chinese Science Bulletin 2010年第6期55卷 478-483页

作者： WANG DeKun jiang XiaoHong ZHAO chunmei WANG ZhiHua WANG Hua DU Zu Liang Key Laboratory of Special Functional Materials of Ministry of Education Henan University Kaifeng 475004 China

Self-organized dithieno [3,2-b:2',3'-d] thiophene-2,5-dicarboxylic acid (A) and dithieno [2,3-b:3',2'-d] thiophene-2,5-dicarboxylic acid (B) films were prepared through solvent-induced order-disorder transition *** arrangement of the two molecules on substrates were observed by atomic force microscopy (AFM),which demonstrated that A was arranged orderly in a certain angle on mica,while B was flat-flying on *** optical and conductance properties in micro region of these two compound films were characterized by UV-vis absorption spectroscopy,fluorescence spectroscopy and conductive atomic force microscopy (C-AFM).The results revealed that the fluorescence and absorption peaks of A had a large red shift in comparison with those of *** conductance of the J-aggregates for A is three orders magnitude higher than that of *** is concluded that the large conductance difference mainly comes from different aggregation structures and orientations of these two molecules on substrate.

关键词：微区结构导电原子力显微镜酸性质紫外可见吸收光谱二元电导性能荧光光谱分子取向

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Raising the production of phloretin by alleviation of by-product of chalcone synthase in the engineered yeast

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Science China(Life Sciences) 2020年第11期63卷 1734-1743页

作者： chunmei jiang Xiaonan Liu Xianqing Chen Yi Cai Yibin Zhuang Tian Liu Xiaoxi Zhu Hui Wang Yuwan Liu Huifeng jiang Wen Wang Key Laboratory for Space Bioscience and Space Biotechnology School of Life SciencesNorthwestern Polytechnical UniversityXi’an 710072China Key Laboratory of Systems Microbial Biotechnology Tianjin Institute of Industrial BiotechnologyChinese Academy of SciencesTianjin 300308China University of Chinese Academy of Sciences Beijing 100049China Center for Ecology and Environmental Sciences Northwestern Polytechnical UniversityXi’an 710072China Jiaxing Synbiolab Biotechnology Co. Ltd.Jiaxing 314006China

Phloretin is an important skin-lightening and depigmenting agent from the peel of apples. Although de novo production of phloretin has been realized in microbes using the natural pathway from plants, the efficiency of phloretin production is still not enough for industrial application. Here, we established an artificial pathway in the yeast to produce phloretin via assembling two genes of p-coumaroyl-CoA ligase(4CL) and chalcone synthase(CHS). CHS is a key enzyme which conventionally condenses a CoA-tethered starter with three molecules of malonyl-CoA to form the backbone of flavonoids. However, there was 33% of byproduct generated via CHS by condensing two molecules of malonyl-CoA during the fermentation process. Hence, we introduced a more efficient CHS and improved the supply of malonyl-CoA through two pathways;the by-product ratio was decreased from 33% to 17% and the production of phloretin was improved from 48 to 83.2 mg L^(-1). Finally, a fed-batch fermentation process was optimized and the production of phloretin reached 619.5 mg L^(-1), which was 14-fold higher than that of the previous studies. Our work established a platform for the biosynthesis of phloretin from the low-cost raw material 3-(4-hydroxyphenyl) propanoic acid and also illustrated the potential for industrial scale bio-manufacturing of phloretin.

关键词： phloretin Saccharomyces cerevisiae metabolic engineering microbial cell factories fed-batch fermentation

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Transcutaneous Auricular Vagus Nerve Stimulation Ameliorates Preeclampsia-Induced Apoptosis of Placental Trophoblastic Cells Via Inhibiting the Mitochondrial Unfolded Protein Response

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Neuroscience Bulletin 2024年第10期40卷 1502-1518页

作者： Jing Zhao Yanan Yang Jiayi Qin Siyu Tao chunmei jiang Huixuan Huang Qiunan Wan Yuqi Chen Shouzhu Xu Haifa Qiao College of Acupuncture and Tuina Shaanxi University of Chinese MedicineXixian New AreaXianyang 712046China Shaanxi Key Laboratory of Acupuncture and Medicine Xixian New AreaXianyang 712046China Department of Public Health Shaanxi University of Chinese MedicineXixian New AreaXianyang 712046China College of Medical Technology Shaanxi University of Chinese MedicineXixian New AreaXianyang 712046China

Preeclampsia is a serious obstetric ***,there is a lack of effective preventive approaches for this *** studies have identified transcutaneous auricular vagus nerve stimulation(taVNS)as a potential novel non-pharmaceutical therapeutic modality for *** this study,we investigated whether taVNS inhibits apoptosis of placental trophoblastic cells through ROS-induced UPR^(mt).Our results showed that taVNS promoted the release of acetylcholine(ACh).ACh decreased the expression of UPR^(mt) by inhibiting the formation of mitochondrial ROS(mtROS),presumably through *** reduced the release of pro-apoptotic proteins(cleaved caspase-3,NF-kB-p65,and cytochrome C)and helped preserve the morphological and functional integrity of mitochondria,thus reducing the apoptosis of placental trophoblasts,improving placental function,and relieving *** study unravels the potential pathophysiological mechanism of ***-depth characterization of the UPR^(mt) is essential for developing more effective therapeutic strategies for preeclampsia targeting mitochondrial function.

关键词： Preeclampsia Transcutaneous auricular vagus nerve stimulation Acetylcholine Reactive oxygen species:Mitochondrial unfolded protein response:Placental trophoblastic cells

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Dalian and Kitakyushu——Fine Example of Sino-Japanese Friendship-City Exchanges

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Voice of Friendship 2010年第3期 24-28页

作者： Liu Fang,jiang chunmei,Jing Shibo

A Sino-Japanese friendship-city relationship was established on May 1, 1979, by Dalian in Northeast China and the southern Japanese city of Kitakyushu that has flourished through the concerted efforts of

关键词： Japanese Dalian Northeast exchanges cooperation fr

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质体工程与抗虫生物技术研究进展

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植物生理学报 2020年第11期56卷 2250-2260页

作者：任白翎姜春妹张江湖北大学生命科学学院省部共建生物催化与酶工程国家重点实验室武汉430062

除了传统细胞核基因组外,植物的质体基因组同样可以实现遗传操作。自从1990年首例质体转基因烟草诞生,越来越多物种的质体转化事件被报道,质体已经成为了植物基因工程、合成生物学和农作物性状改良的热点研究领域。本文简要阐述了质体... 详细信息

除了传统细胞核基因组外,植物的质体基因组同样可以实现遗传操作。自从1990年首例质体转基因烟草诞生,越来越多物种的质体转化事件被报道,质体已经成为了植物基因工程、合成生物学和农作物性状改良的热点研究领域。本文简要阐述了质体基因工程的特点、转化技术和质体合成生物学,重点阐述了质体工程在作物抗虫领域取得的进展。

关键词：质体工程抗虫生物技术合成生物学

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Comparison of the antitumor mechanisms of iturin A using 2D and 3D cultures of HepG2 cell

Comparison of the antitumor mechanisms of iturin A using 2D ...

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2018年中国肿瘤标志物学术大会暨第十二届肿瘤标志物青年科学家论坛

作者： Haobin Zhao Dongyan Shao chunmei jiang Junling Shi 西北工业大学

To compare the results obtained in 2 D and 3 D cultures and make accurate evaluation on the antitumor potential of iturin A on HepG2 cells, both cultures were developed in this study. For 3 D culture, cells were collected to prepare cell suspension and mixed with Matrigel Matrix. The antitumor activity was tested and the mechanisms were analyzed. As results, iturin A showed significant and concentration-dependent inhibitory effect on the growth of HepG2 cells in both 2 D and 3 D cultures with IC50 of 11.80 μM and 55.26 μM, respectively. Moreover, ROS burst and DNA damage occurred in cells treated with iturin A in 2 D and 3 D cultures. The endogenous apoptosis pathway was proved to occur by Western blot analysis in 2 D and 3 D cultures. In 2 D culture, the treated cells showed a large number of vacuoles in the cytoplasm in photography. And chromatin condensation and marginalization,nuclear decomposition, ER and mitochondria swelling were observed in TEM detection. Untreated cells did not show the above change in morphology. These morphologies indicated the simultaneous occurrence of apoptosis and paraptosis in cells treated with iturin A. However, in 3 D culture, induction of paraptosis was not observed, although the induction of apoptosis and autophagy was ***, in 2 D culture, the up-regulated expression of LC 3 II and the occurrence of autophagosomes suggested the occurrence of autophagy. However, the expression of p62 was not down-regulated as expected, but up-regulated, instead. In 3 D culture, iturin A significantly increased expression of LC3 II and decreased expression of p62 and caused autophagy in iturin A-treated cells. These indicate that autophagy activity in treated cells in 2 D culture was very strong. Comparatively, 2 D culture resulted in lower IC50 and multiple pathways for the inhibitory effect of iturin A on HepG2 cells. Iturin A exhibited induction of apoptosis, autophagy, and paraptosis in 2 D culture of HepG2 cell, but only apoptosi

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一类马氏调节反射跳扩散过程的平稳性（英文）

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应用概率统计 2017年第1期33卷 32-48页

作者：蒋春梅西安交通大学城市学院西安710018

本文拓展文献[1]的马氏调节反射布朗运动模型到马氏调节反射跳-扩散过程,其中跳元素被表述为一个马氏调节复合泊松过程.我们主要计算有关该马氏调节反射跳-扩散过程的平稳分布.我们用一个具有两状态例子通过合适的边界条件来说明如何求... 详细信息

本文拓展文献[1]的马氏调节反射布朗运动模型到马氏调节反射跳-扩散过程,其中跳元素被表述为一个马氏调节复合泊松过程.我们主要计算有关该马氏调节反射跳-扩散过程的平稳分布.我们用一个具有两状态例子通过合适的边界条件来说明如何求解平稳分布所满足的积分-微分方程组.最后,作为一个特殊情况,我们给出无马氏调节反射-扩散过程的平稳分布.

关键词：马氏调节反射跳扩散平稳分布

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违约风险下篮子期权的定价（英文）

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南开大学学报（自然科学版） 2019年第6期52卷 71-83页

作者：蒋春梅西安交通大学城市学院

研究了基于大规模信用投资组合的篮子期权的定价.投资组合中潜在交易的风险资产假设具有违约风险和违约传染,进一步,资产价格的动态与其违约强度相互耦合.通过求解相关的里卡提方程以及应用经验测度值过程的弱收敛和Vitali收敛定理,建... 详细信息

研究了基于大规模信用投资组合的篮子期权的定价.投资组合中潜在交易的风险资产假设具有违约风险和违约传染,进一步,资产价格的动态与其违约强度相互耦合.通过求解相关的里卡提方程以及应用经验测度值过程的弱收敛和Vitali收敛定理,建立了当资产数量趋于无穷时,相关篮子期权价格的闭形式表示.

关键词：篮子期权违约风险里卡提方程弱收敛

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