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A new fabrication method for enhancing the yield of linear micromirror arrays assisted by temporary anchors

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Microsystems & Nanoengineering 2024年第3期10卷 169-180页

作者： Xingchen Xiao Ting Mao Yingchao shi Kui Zhou jia Hao Yiting yu Ningbo Institute of Northwestern Polytechnical University College of Mechanical EngineeringNorthwestern Polytechnical University710072 Xi’anChina Key Laboratory of Micro/Nano Systems for Aerospace(Ministry of Education) Shaanxi Province Key Laboratory of Micro and Nanoelectromechanical SystemsNorthwestern Polytechnical University710072 Xi’anChina

As one of the most common spatial light modulators,linear micromirror arrays(MMAs)based on microelectromechanical system(MEMS)processes are currently utilized in many ***,two crucial challenges exist in the fabrication of such devices:the adhesion of silicon microstructures caused by anodic bonding and the destruction of the suspended silicon film due to residual *** solve these issues,an innovative processing method assisted by temporary anchors is *** approach effectively reduces the span of silicon microstructures and improves the Euler buckling limit of the silicon ***,these temporary anchors are strategically placed within the primary etching areas,enabling easy removal without additional processing *** a result,we successfully achieved wafer-level,high-yield manufacturing of linear MMAs with a filling factor as high as 95.1%.Demonstrating superior capabilities to those of original MMAs,our enhanced version boasts a total of 60 linear micromirror elements,each featuring a length-to-width ratio of 52.6,and the entire optical aperture measures 5 mm×6 *** linear MMA exhibits an optical deflection angle of 20.4°at 110 Vdc while maintaining exceptional deflection flatness and *** study offers a viable approach for the design and fabrication of thin-film MEMS devices with high yields,and the proposed MMA is promising as a replacement for digital micromirror devices(DMDs,by TI Corp.)in fields such as spectral imaging and optical communication.

关键词： mirror exceptional anodic

Sperm of rosy barb (Puntius conchonius) as an in vitro assay system of nonylphenol cytotoxicity

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Journal of Environmental Sciences 2006年第3期18卷 417-419页

作者： XIAO Qin ZHANG shi-cui HU jia-hui XU yu-yan Department of Marine Biology Ocean University of China Qingdao 266003 China. Department of Life Science Liaocheng University Liaocheng 252059 China

Nonylphenol （NP） is the final degradation product of alkylphenol polyethoxylates （APEs）, which are widely present in plastics, papers, pulp, detergents, pesticides, herbicides, paints and cosmetics. It is estimated that annual global production of APEs is about 500000 t, 60% of which eventually ends up in aquatic ecosystems primarily via wastewater （So16 et cd., 2000）. NP is resistant to biodegradation and persistent in the environment （Arukwe et al., 2000）.

关键词： motility nonylphenol rosy barb sperm ultrastructure

Stable Real-Time Surgical Cutting Simulation of Deformable Objects Embedded with Arbitrary Triangular Meshes

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Journal of Computer Science & Technology 2017年第6期32卷 1198-1213页

作者： shi-yu jia Zhen-Kuan Pan Guo-Dong Wang Wei-Zhong Zhang Xiao-Kang yu College of Computer Science and Technology Qingdao University Qingdao 266071 China

Surgical simulators need to simulate deformation and cutting of deformable objects. Adaptive octree mesh based cutting methods embed the deformable objects into octree meshes that are recursively refined near the cutting tool trajectory. Deformation is only applied to the octree meshes; thus the deformation instability problem caused by degenerated elements is avoided. Biological tissues and organs usually contain complex internal structures that are ignored by previous work. In this paper the deformable objects are modeled as voxels connected by links and embedded inside adaptive octree meshes. Links swept by the cutting tool are disconnected and object surface meshes are reconstructed from disconnected links. Two novel methods for embedding triangular meshes as internal structures are proposed. The surface mesh embedding method is applicable to arbitrary triangular meshes, but these meshes have no physical properties. The material sub-region embedding method associates the interiors enclosed by the triangular meshes with physical properties, but requires that these meshes are watertight, and have no self-intersections, and their smallest features are larger than a voxel. Some local features are constructed in a pre-calculation stage to increase simulation performance. Simulation tests show that our methods can cut embedded structures in a way consistent with the cutting of the deformable objects. Cut fragments can also deform correctly along with the deformable objects.

关键词： surgical simulation physically based modeling deformable object interactive cutting adaptive octree mesh

Ensemble learning prediction of soybean yields in China based on meteorological data

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Journal of Integrative Agriculture 2023年第6期22卷 1909-1927页

作者： LI Qian-chuan XU shi-wei ZHUANG jia-yu LIU jia-jia ZHOU Yi ZHANG Ze-xi Agricultural Information Institute Chinese Academy of Agricultural SciencesBeijing 100081P.R.China Beijing Engineering Research Center for Agricultural Monitoring and Early Warning Beijing 100081P.R.China Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100094P.R.China The Department of Mathematics Columbia UniversityNY 10027USA Key Laboratory of Agricultural Monitoring and Early Warning Technology Ministry of Agriculture and Rural AffairsBeijing 100081P.R.China

The accurate prediction of soybean yield is of great significance for agricultural production, monitoring and early *** previous studies have used machine learning algorithms to predict soybean yield based on meteorological data,it is not clear how different models can be used to effectively separate soybean meteorological yield from soybean yield in various regions. In addition, comprehensively integrating the advantages of various machine learning algorithms to improve the prediction accuracy through ensemble learning algorithms has not been studied in depth. This study used and analyzed various daily meteorological data and soybean yield data from 173 county-level administrative regions and meteorological stations in two principal soybean planting areas in China(Northeast China and the Huang–Huai region), covering 34 *** effective machine learning algorithms(K-nearest neighbor, random forest, and support vector regression) were adopted as the base-models to establish a high-precision and highly-reliable soybean meteorological yield prediction model based on the stacking ensemble learning framework. The model's generalizability was further improved through 5-fold crossvalidation, and the model was optimized by principal component analysis and hyperparametric optimization. The accuracy of the model was evaluated by using the five-year sliding prediction and four regression indicators of the 173 counties, which showed that the stacking model has higher accuracy and stronger robustness. The 5-year sliding estimations of soybean yield based on the stacking model in 173 counties showed that the prediction effect can reflect the spatiotemporal distribution of soybean yield in detail, and the mean absolute percentage error(MAPE) was less than 5%. The stacking prediction model of soybean meteorological yield provides a new approach for accurately predicting soybean yield.

关键词： meteorological factors ensemble learning crop yield prediction machine learning county-level

Towards efficiency in rare disease research： what is distinctive and important？

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Science China(Life Sciences) 2017年第7期60卷 686-691页

作者： Jinmeng jia Tieliu shi The Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biology the Institute of Biomedical Sciences and School of Life Sciences East China Normal University Shanghai 200241 China

Characterized by their low prevalence, rare diseases are often chronically debilitating or life threatening. Despite their low prevalence, the aggregate number of individuals suffering from a rare disease is estimated to be nearly 400 million *** the past decades, efforts from researchers, clinicians, and pharmaceutical industries have been focused on both the diagnosis and therapy of rare diseases. However, because of the lack of data and medical records for individual rare diseases and the high cost of orphan drug development, only limited progress has been achieved. In recent years, the rapid development of next-generation sequencing(NGS)-based technologies, as well as the popularity of precision medicine has facilitated a better understanding of rare diseases and their molecular etiology. As a result, molecular subclassification can be identified within each disease more clearly, significantly improving diagnostic accuracy. However, providing appropriate care for patients with rare diseases is still an enormous challenge. In this review, we provide a brief introduction to the challenges of rare disease research and make suggestions on where and how our efforts should be focused.

关键词： rare disease rare disease diagnosis and treatment data standard data sharing orphan drugs

A direct electrochemical biosensor for rapid glucose detection based on nitrogen-doped carbon nanocages

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Rare Metals 2024年第5期43卷 2184-2192页

作者： Lan-Lan Li yu Zhao Li-jia Pan jian-Bin Xu Yi shi College of Mechanical and Electrical Engineering Henan Agricultural UniversityZhengzhou 450002China School of Electronic Science and Engineering Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing210093China Department of Electronic Engineering The Chinese University of HongKongHongkong 999077China

Given the increasing number of diabetic patients,rapid and accurate detection of glucose in body fluids is *** study developed a direct electrochemical biosensor for glucose based on nitrogen-doped carbon nanocages(NCNCs).NCNCs possess a large specific surface area of 1395 m^(2)·g^(-1),a high N atomic content of 9.37%and good biocompatibility,which is favorable for enzyme loading and electron *** surface average concentration of electroactive glucose oxidase on NCNCs was 2.82×10^(-10)mol·cm^(-2).The NCNC-based direct electrochemical biosensor exhibited a high sensitivity of 13.7μA·(mmol·L^(-1))^(-1)·cm^(-2),rapid response time of 5 s and an impressive electron-transferrate constant(ks)of 1.87 s^(-1).Furthermore,we investigated an NCNC-based direct electron transfer(DET)biosensor for sweat glucose detection,which demonstrated tremendous promise for non-invasive wearable diabetes diagnosis.

关键词： Direct electron transfer(DET) Nitrogen-doped carbon nanocages(NCNCs) Glucose oxidase Biosensor

Pyrrole/macrocycle/MOF supramolecular co-assembly for flexible solid state supercapacitors

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Chinese Chemical Letters 2021年第9期32卷 2773-2776页

作者： Shan-Shan jia Wen-shi Xu Yong Chen yu Liu College of Chemistry State Key Laboratory of Elemento-Organic ChemistryNankai UniversityTianjin 300071China

Supramolecular assemblies constructed through the encapsulation of conductive polymers(CPs)by macrocyclic molecules have attracted increasing interest in the fields of supramolecular chemistry and *** this work,an effective strategy was reported to improve the stability and conductivity of CPs by electrochemically constructing different supramolecular assemblies composed of macrocycles and ***,we uploaded zinc-based MOF(ZIF-8)onto carbon nanotube film(CNTF)and further electrically deposited macrocycles and CPs to gain the flexible conductive ***,five different supramolecular macrocycles,includingα-cyclodextrin(α-CD),sulfato-β-cyclodextrin(SCD),sulfonatocalix[4]arene(SC[4]),cucurbit[6]uril(CB[6])and cucurbit[7]uril(CB[7])were utilized and the electrochemical performances of the assembly electrodes increased in an order ofα-CD

关键词： Supramolecular assemblies Macrocycle Conductive polymers Electrochemical performance Cationic radical

Effect of Interfacial Adsorption on the Stability of Thin Polymer Films in a Solvent-induced Process

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Chinese Journal of Polymer Science 2021年第4期39卷 501-511,I0008页

作者： Lin Xu Tong-Fei shi Li-jia An yu-yuan Lu Li-Na Wang Innovation Center for Textile Science and Technology Donghua UniversityShanghai201620China State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China Testing and Analysis Center Hebei Normal UniversityShijiazhuang 050024China

The stability of ultrathin polymer films plays a crucial role in their technological ***,we systematically investigated the influence of interfacial adsorption in physical aging and the stability of thin polymer films in the solvent-induced *** further identify the stability mechanism from the theory of thin film *** results show that the aging temperature and film thickness can strongly influence the stability of thin PS films in acetone *** aging can greatly improve the stability of thin polymer films when the aging temperature T_(aging1)>T_(g).A thinner PS film more quickly reaches a stable state via physical *** short aging time,the formation of the adsorbed layer can reduce the polar interaction;however,it slightly influences the stability of thin polymer films in the solvent-induced *** later aging stage,the conformational rearrangement of the polymer chains induced by the interfacial effect at the aging temperature Taging1 plays an important role in stabilizing the thin polymer ***,at T_(aging2)

关键词： Thin polymer film Interfacial adsorption Dewetting Swelling process

SAR imaging method based on coprime sampling and nested sparse sampling

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Journal of Systems Engineering and Electronics 2015年第6期26卷 1222-1228页

作者： Hongyin shi Baojing jia School of Information Science and Engineering Yan Shan University

As the signal bandwidth and the number of channels increase, the synthetic aperture radar （SAR） imaging system produces huge amount of data according to the Shannon-Nyquist theorem, causing a huge burden for data transmission. This paper concerns the coprime sampl which are proposed recently but ng and nested sparse sampling, have never been applied to real world for target detection, and proposes a novel way which utilizes these new sub-Nyquist sampling structures for SAR sampling in azimuth and reconstructs the data of SAR sampling by compressive sensing （CS）. Both the simulated and real data are processed to test the algorithm, and the results indicate the way which combines these new undersampling structures and CS is able to achieve the SAR imaging effectively with much less data than regularly ways required. Finally, the influence of a little sampling jitter to SAR imaging is analyzed by theoretical analysis and experimental analysis, and then it concludes a little sampling jitter have no effect on image quality of SAR.

关键词： synthetic aperture radar (SAR) imaging compressivesensing coprime sampling nested sparse sampling.