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Partition Behavior of Penicillin in Three-liquid-phase Extraction System

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过程工程学报 2006年第3期6卷 363-368页

作者：谭显东季清荣常志东 Dept. Environ. Eng. Chengdu Univ. Information Technol.ChengduSichuan 610225China State Key Lab. Biochem. Eng. Lab. Sep. Sci. & Eng.Inst. Process Eng.CASBeijing 100080China

Partition behavior of penicillins G and V was studied in a novel three-liquid-phase extraction system,which is composed of butyl acetate (BA),polyethylene glycol (PEG),ammonia sulfate (NH4)2SO4 and water (H2O). The main components in the top,middle and bottom phases are butyl acetate,polyethylene glycol aqueous solution and ammonia sulfate aqueous solution,respectively. Some parameters such as partition coefficients Di/j and mass fractions Ei of penicillins G and V were determined at the room temperature,respectively. Experimental efforts have been made to investigate the partition behavior of penicillin in the three-liquid-phase extraction system,including initial concentrations of phase-forming components PEG and (NH4)2SO4,PEG molecular weight,pH,initial concentration of penicillin. The results indicated that penicillins G and V have the similar partition behavior. They preferentially distribute into the middle phase with the increase of initial concentration of phase-forming components and into the top phase with the decrease of pH,while partition coefficient Dm/b is hardly affected by pH value. The variation of PEG molecular weight has little effect on mass fractions of penicillin. The increase of initial concentration of penicillins G and V could lead to the increase of Dt/b,Dm/b and the decrease of Dt/m,while their mass fractions in all phases were almost independent on their initial concentrations.

关键词： three-phase extraction penicillin partition

Earthquake dynamic response behavior of Xiangchong valley type tailings impoundment in Yunnan, China

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Journal of Mountain Science 2018年第1期15卷 82-99页

作者： REN Zhe WANG Kun ZHANG Qi-shu XU Ze-min TANG Zheng-guang CHEN ji-pu YANG ji-qing XU Zong-heng Faculty of Civil Engineering and Mechanics Kunming University of Science and Technology College of Architectural Engineering Yunnan Agricultural University School of Tourism and Geographical Science Yunnan Normal University

Tailings impoundments can potentially collapse due to damage caused by earthquakes,which has frequently occurred around the *** study takes the proposed valley type tailings impoundment in Yunnan as the research object to analyze the dynamic response behavior under earthquake action with both numerical simulation and physical model test(1:300).The results of both tests show that the dynamic response of the valley type tailings impoundment is characterized by"medium stiffness effect",in other words,in a certain range,the"softer"the unsaturated tailings sand is,the more energy it can dissipate,which leads the decrease of the value of the acceleration amplification *** addition,the peak acceleration of the monitoring points increases with the vertical elevation,which indicates that the"elevation amplification effect"exists in the tailings impoundment dynamic *** middle part of the outer side of the raised embankment reacts more sensitive than the crest,which is similar to the slope dynamic *** starter dam reacts sensitively under the earthquake excitation,which should be given more attention during the seismic *** dynamic response rules reflected by the numerical simulation are consistent with the results monitored on the physical model test,although there are some differences between their *** dynamic response rules of the valley type tailings impoundment can provide basis for the design of the similar projects in this region.

关键词： Tailings impoundment Dynamic response Shaking table test Medium stiffness effect

The Sublethal Effects of Chlorantraniliprole on Helicoverpa armigera (Lepidoptera: Noctuidae)

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Journal of Integrative Agriculture 2013年第3期12卷 457-466页

作者： ZHANG Rui-min DONG Jun-feng CHEN jia-hua ji qing-e CUI jin-jie Department of Plant Protection Fujian Agriculture and Forestry University College of Forestry Henan University of Science and Technology Institute of Cotton Research Chinese Academy of Agricultural Sciences

Sublethal effects of chlorantraniliprole to Helicoverpa armigera （Hiibner） larvae were evaluated through exposure of third instar larvae to the insecticide incorporated into an artificial diet. When larvae were fed on the insecticide-containing diet for 7 d, the LC10, LC20, LC40, and LC50values were 3.790, 7.977, 21.577, and 33.121 μg active ingredient L^-1, respectively. Chlorantraniliprole at sublethal concentrations significantly reduced the larval body mass, emergence ratio, adult longevity and egg hatching rate in both the parental and offspring generations. The pupation and copulation rate in the parental generation and the pupal mass in the offspring also strongly decreased. Reproduction was seriously disturbed in both the parental and offspring groups even when only one of the partners was exposed to chlorantraniliprole at larval stages. However, at the lowest concentration of exposure （LC^0）, offspring fecundity was strongly reduced only when both partners were exposed. The net reproductive rate （R0）, intrinsic rate of increase （rm）, and gross reproduction rate （GRR） at LC20, LC40 concentrations were significantly lower than that of the control. Post-exposure effects also included an extended larval developmental time and increased male proportion in both generations. The doubling time （Dt） at LC20, LC40 concentrations as well as gross reproduction rate （GRR） at LC10 concentration were also significantly increased. Chlorantraniliprole might have significant effects on H. armigera population dynamics even at sublethal concentrations on both parental and offspring generations.

关键词： Helicoverpa armigera chlorantraniliprole sublethal effects sublethal concentration

Oxygen transfer phenomenon between slag and molten steel for production of IF steel

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Journal of Iron and Steel Research International 2020年第4期27卷 402-408页

作者： Yun-qing ji Chun-yang Liu Hui-xiang Yu Xiao-xuan Deng Fu-xiang Huang Xin-hua Wang School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Steelmaking Plant Beijing Shougang Co.Ltd.Qian’an 100041HebeiChina Research Institute of Technology Shougang Group Co.Ltd.Beijing 100043China

FeO-containing slag originated from the basic oxygen furnace to the ladle is a major reoxidation source during the following secondary *** slag reduction treatment(slag treatment)is one of the common countermeasures adopted to eliminate the steel contamination by FeO *** oxygen transfer phenomenon between molten steel and slag was studied during the industrial production of interstitial-free(IF)steel,the measured and calculated oxygen activities in steel were compared,and the Fe–O equilibrium at the slag–molten steel interface was investigated by thermodynamic *** slag treatment,the oxygen potential is higher in the molten steel than in the pre-deoxidation slag;this causes oxygen transfer from the molten steel to the slag,decreasing the efficiency of slag *** on this,a two-step slag deoxidation process was *** second step further reduced the FeO *** the other hand,the CaO/Al2O3(C/A)ratio in the refining slag must be controlled,because it affects the FeO activity and inclusion absorption capacity of the *** results suggest that the C/A ratio of 1.2–1.5 and the FeO content of\6%are beneficial to refine IF steel.

关键词： Oxygen transfer IF steel Deoxidation Slag treatment Refining slag

Expression for peroxisome proliferator-activated receptor gamma in pituitary adenomas 38 cases for semi-quantitative immunohistochemical analysis

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Neural Regeneration Research 2008年第7期3卷 756-759页

作者： Xiaojie Lu Kailai Chen Weiyang ji qing Wang Bing Li jiang＇an Li jiyong Sun Department of Neurosurgery Wuxi Second Hospital Affiliated to Nanjing Medical University Wuxi 214002 Jiangsu Province China

BACKGROUND： It has been reported that peroxisome proliferator-activated receptor γ （PPAR γ ） is highly expressed in lung cancer, colon cancer, and gastric cancer, as well as other tumors.OBJECTIVE： To study expression of PPAR γ in pituitary adenomas and analyze the role of PPAR γ in hormonal typing of pituitary adenomas. DESIGN, TIME AND SETTING： Semi-quantitative immunohistochemistry of pathological specimens. The experiment was conducted at the Department of Neurosurgery, Wuxi Second Hospital Affiliated to Nanjing Medical University between January 2002 and May 2005. MATERIALS： Surgical resection samples of pituitary adenomas from 38 cases （18 male and 20 female） were analyzed. Eight cases were determined to be invasive pituitary adenomas and 30 cases were non-invasive pituitary adenomas. Hormonal classification of the types of pituitary adenomas revealed somatotrophic adenomas in six cases, corticotrophic adenoma in five cases, prolactinomas in 13 cases, multi-hormone secreting adenomas in six cases, and eight cases of adenoma without altered endocrine function. Five autopsy specimens were collected during the same period from patients of matching age that died from unrelated diseases and were included as normal anterior pituitar3, controls. METHODS： Cell counts for positive immunohistochemical signals were recorded from histopathological sections. The percentage of positive cells was reported as a semi-quantitative analysis. MAIN OUTCOME MEASURES： The rate of PPAR γ positive cells in different types of adenoma was based on hormonal levels and invasiveness of pituitary tumor cells. RESULTS： All tumor biopsies were determined to express PPAR γ. The rate of PPAR γ -positive cells ranged between 8%-65% in the pituitary adenomas. According to hormonal type, PPAR γ expression did not vary between the groups. In addition, there was no significant difference in PPAR γ expression between the non-invasive and invasive pituitary adenomas. CONCLUSIONS： Human p

关键词： Peroxisome proliferator-activated receptor γ pituitary adenomas immunohistochemistry

Efficacy of ilaprazole in the treatment of duodenal ulcers:A meta-analysis

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World Journal of Gastroenterology 2014年第17期20卷 5119-5123页

作者： Xi-qing ji Jun-Feng Du Gang Chen Guang Chen Bo Yu Department of General Surgery General Hospital of Beijing Military Command of People’s Liberation Army

AIM: To compare the efficacy and tolerance of ilaprazole compared with other proton pump inhibitors (PPIs) in the treatment of duodenal ulcer.

关键词： Ilaprazole Proton pump inhibitor Duodenal ulcer Meta-analysis

Measures of Asymmetry Dual to Mean Minkowski Measures of Asymmetry for Convex Bodies

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Communications in Mathematical Research 2016年第3期32卷 207-216页

作者： yao dan guo qi ji You-qing department of mathematics suzhou university of science and technologySuzhouJiangsu215009 不详

Khovanov type homology is a generalization of Khovanov *** main result of this paper is to give a recursive formula for Khovanov type homology of pretzel knots P（-n,-m, m）. The computations reveal that the rank of the homology of pretzel knots is an invariant of n. The proof is based on a ＂shortcut＂ and two lemmas that recursively reduce the computational complexity of Khovanov type homology.

关键词： pretzel knot Khovanov type homology Frobenius algebra TQFT

On Properties of p-critical Points of Convex Bodies

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Communications in Mathematical Research 2015年第2期31卷 161-170页

作者： Huang Xing Guo Qi ji You-qing Department of Mathematics Suzhou University of Science and Technology

Properties of the p-measures of asymmetry and the corresponding affine equivariant p-critical points, defined recently by the second author, for convex bodies are discussed in this article. In particular, the continuity of p-critical points with respect to p on （1, ＋∞） is confirmed, and the connections between general p-critical points and the Minkowski-critical points （∞-critical points） are investigated. The behavior of p-critical points of convex bodies approximating a convex bodies is studied as well.

关键词： convex body p-critical point Minkowski measure of asymmetry p-measure of asymmetry

Filamentation of Metabolic Enzymes in Saccharomyces cerevisiae

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Journal of Genetics and Genomics 2016年第6期43卷 393-404页

作者： qing-ji Shen Hakimi Kassim Yong Huang Hui Li jing Zhang Guang Li Peng-Ye Wang Jun Yan Fangfu Ye ji-Long Liu Medical Research Council Functional Genomics Unit Department of PhysiologyAnatomy and GeneticsUniversity of Oxford Key Laboratory of Entomology and Pest Control Engineering College of Plant ProtectionSouthwest University Key Laboratory of Soft Matter Physics Beijing National Laboratory for Condensed Matter PhysicsInstitute of PhysicsChinese Academy of Sciences CAS-MPG Partner Institute for Computational Biology Shanghai Institutes of Biological SciencesChinese Academy of Sciences

Compartmentation via filamentation has recently emerged as a novel mechanism for metabolic regulation. In order to identify filamentforming metabolic enzymes systematically, we performed a genome-wide screening of all strains available from an open reading frameGFP collection in Saccharomyces cerevisiae. We discovered nine novel filament-forming proteins and also confirmed those identified previously. From the 4159 strains, we found 23 proteins, mostly metabolic enzymes, which are capable of forming filaments in vivo. In silico protein-protein interaction analysis suggests that these filament-forming proteins can be clustered into several groups, including translational initiation machinery and glucose and nitrogen metabolic pathways. Using glutamine-utilising enzymes as examples, we found that the culture conditions affect the occurrence and length of the metabolic filaments. Furthermore, we found that two CTP synthases（Ura7p and Ura8p） and two asparagine synthetases（Asn1p and Asn2p） form filaments both in the cytoplasm and in the *** imaging analyses suggest that metabolic filaments undergo sub-diffusion. Taken together, our genome-wide screening identifies additional filament-forming proteins in S. cerevisiae and suggests that filamentation of metabolic enzymes is more general than currently appreciated.

关键词： CTP synthase Metabolic enzyme Cytoophidium Glycolysis Glutamine Intracellular compartmentation Saccharomyces cerevisiae