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Enhanced thermoelectric properties of NbCoSn half-Heuslers through in-situ nanocrystallization of amorphous precursors during the consolidation process

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Journal of Materials Science & Technology 2023年第34期165卷 39-48页

作者： Chanwon Jung Kyuseon jang Hail Park Jeongin jang Hanhwi jang Byungchul Kang Kitae Park Siyuan Zhang Ruben Bueno Villoro SuDong Park Ho Jin Ryu Yeon Sik Jung min-Wook Oh Christina Scheu Seong-Hoon Yi Pyuck-Pa Choi Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Republic of Korea Max-Planck-Institut für Eisenforschung GmbH Düsseldorf 40237Germany Electrical Materials Research Division Energy Conversion Research CenterKorea Electrotechnology Research Institute(KERI)Changwon 51543Republic of Korea Department of Materials Science and Metallurgical Engineering Kyungpook National University80 DaehakroDaegu 41566Republic of Korea Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Republic of Korea Department of Materials Science and Engineering Hanbat National University125 Dongseodae-roYuseong-guDaejeon 34158Republic of Korea

Tailoring nanostructures is a general approach used to obtain enhanced thermoelectric properties for halfHeusler compounds because the wide areas of grain and phase boundaries could be scattering centers that lower lattice thermal ***,a common fabrication method based on the sintering of crystalline precursors crushed from as-cast alloy ingots has limitations in obtaining a homogeneous microstructure without microsized impurity phases,owing to residual elemental segregation from *** this study,we used amorphous NbCoSn alloys as a precursor for the sintered specimen to obtain a homogeneous NbCoSn bulk specimen without microsized impurity phases and segregation,which led to the enhanced Seebeck coefficient due to the high purity of the half-Heusler phase after ***,superplasticity originating from amorphous features enabled the powders to be largely deformed during the sintering process,even at a low sintering temperature(953 K).This resulted in less oxidation at both,the grain boundary and the interior,as the O diffusion pathway was blocked during the sintering *** a result,the NbCoSn0.95Sb0.05 specimen using an amorphous precursor exhibited an enhanced zT of 0.7,due to the increase in the power factor and a decrease in lattice thermal conductivity compared to the specimen using a crystalline precursor.

关键词： Half-Heusler compounds Amorphous Superplasticity Segregation Atom probe tomography

Electroacupuncture for abdominal pain relief in patients with acute pancreatitis:A three-arm randomized controlled trial

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Journal of Integrative Medicine 2023年第6期21卷 537-542页

作者： Dong Kee jang Jun Kyu Lee Chan Yung Jung Kyung Ho Kim Ha Ra Kang Yeon Sun Lee Jong Hwa Yoon kwang Ro Joo min Kyu Chae Yong Hyeon Baek Byung-Kwan Seo Sang Hyub Lee Chiyeon Lim Department of Internal Medicine Seoul Metropolitan Government Boramae Medical CenterSeoul National University College of MedicineSeoul 07061Republic of Korea Department of Internal Medicine Dongguk University Ilsan HospitalDongguk University College of MedicineGoyang 10326Republic of Korea Department of Acupuncture and Moxibustion Dongguk University Ilsan Oriental HospitalCollege of Korean MedicineDongguk UniversityGoyang 10326Republic of Korea Department of Korean Medicine Dongguk UniversityGoyang 10326Republic of Korea Department of Acupuncture and Moxibustion College of Korean MedicineDongguk UniversityGyeongju 38067Republic of Korea Department of Gastroenterology Kyung Hee University Hospital at GangdongSeoul 05278Republic of Korea Department of Acupuncture and Moxibustion Kyung Hee University Korean Medicine Hospital at GangdongSeoul 05278Republic of Korea Department of Internal Medicine and Liver Research Institute Seoul National University HospitalSeoul National University College of MedicineSeoul 03080Republic of Korea Department of Biostatistics College of MedicineDongguk UniversityGoyang 10326Republic of Korea

Background: Electroacupuncture(EA) may reduce the severity of acute pancreatitis(AP) and provide additional pain relief in patients with chronic pancreatitis. However, the ability of EA to relieve pain in patients with AP has not been well ***: This study was undertaken to compare the pain-relieving effects of EA and conventional treatment in patients with ***, setting, participants and interventions: This study was conducted using a randomized, controlled,three-arm, parallel-group and multi-center design. Patients diagnosed with AP were randomly and equally assigned to EA1, EA2 or control groups. All participants received conventional standard-of-care therapy for AP. Local EA alone was administered in EA1, and local plus distal EA was given in *** EA included two abdominal acupoints, while distal EA included twelve peripheral acupoints. EA groups underwent one session of EA daily for 4 days(days 1–4), or until pain was resolved or *** outcome measures: The primary outcome measure was the change in the visual analogue scale(VAS;0–100) pain score between baseline and day ***: Eighty-nine participants were randomized into EA1, EA2 and control groups, and 88(EA1, 30;EA2, 29;control, 29) were included in the full-analysis set. VAS score change(median [interquartile range]) on day 5 was(12.3 ± 22.5) in the EA1 group,(10.3 ± 21.5) in the EA2 group, and(8.9 ± 15.2) in the control group. There were not significant differences in the change in VAS score among treatments(P = 0.983). However, time to food intake was significantly shorter in the EA group(EA1 + EA2) than in the control group(median 2.0 days vs 3.0 days), with a hazard ratio of 0.581(P = 0.022;95% CI,0.366–0.924). No significant adverse events ***: EA treatment did not significantly reduce pain after 4 days of treatment in patients with AP-associated abdominal pain but significantly reduced time to first food intake.

关键词： Acute pancreatitis Electroacupuncture Pain management Abdominal pain Randomized controlled trial

Duodenal variceal bleeding after balloon-occluded retrograde transverse obliteration: Treatment with transjugular intrahepatic portosystemic shunt

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World Journal of Gastroenterology 2012年第22期18卷 2877-2880页

作者： min Joung Kim Byoung Kuk jang Woo Jin Chung Jae Seok Hwang Young Hwan Kim Department of Gastroenterology Keimyung University School of Medicine Dongsan Medical Center 194 Dongsan-dong Jung-gu Daegu 700-712 South Korea Department of Diagnostic Radiology Keimyung University School of Medicine Dongsan Medical Center 194 Dongsan-dong Jung-gu Daegu 700-712 South Korea

We report a case of duodenal varix bleeding as a long term complication of balloon occluded retrograde transvenous obliteration (BRTO), which was successfully treated with a transjugular intrahepatic portosystemic shunt (TIPS). A 57-year-old man was admitted to the emergency room suffering from melena. He had under-gone BRTO to treat gastric varix bleeding 5 mo before admission. Endoscopy and a computed tomography (CT) scan showed complete obliteration of the gastric varix, but the nodular varices in the second portion of the duodenum expanded after BRTO, and spurting blood was seen. TIPS was performed for treatment of duodenal variceal bleeding, because attempts at endoscopic varix ligation were unsuccessful. The post-operative course was uneventful and the patient was discharged without complications. A follow up CT scan obtained 21 mo after TIPS revealed a patent TIPS tract and complete obliteration of duodenal varices, but multinodular hepatocellular carcinoma had developed. He died of hepatic failure 28 mo after TIPS.

关键词： Duodenal variceal bleeding Balloon occlud-ed retrograde transvenous obliteration Transjugularintrahepatic portosystemic shunt

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Neural Regeneration Research 2011年第4期6卷 283-287页

作者： Sung Ho jang Sang-Hyun Cho Mi Young Lee Yong Hyun Kwon min Cheul Chang Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityDaegu 705-717Republic of Korea Department of Physical Therapy Institute of Health ScienceYonsei University College of Health ScienceWounju-siGangwon-do 220-710Republic of Korea Department of Physical Therapy College of Health and TherapyDaegu Haany UniversitySuseongkuDaegu 706-060Republic of Korea Department of Physical Therapy Yeungnam College of Science and TechnologyNamkuDaegu 705-703Republic of Korea

The corticospinal tract （CST） is one of the most important neural tracts for motor function in the human brain. Little is known about age-related changes of the CST. tn this study, we tried to evaluate age-related changes of the CST using diffusion tensor imaging in 60 healthy subjects. The diffusion tensor imaging result revealed that the tract number and fractional anisotropy value were decreased, and the apparent diffusion coefficient （ADC） value was increased with aging. The distribution showed a semilog pattern for tract number, fractional anisotropy and ADC of the CST, and the pattern of each graph was near-linear. When compared with the diffusion tensor imaging parameters of subjects in the 20 s age group, tract number and fractional anisotropy values were significantly decreased in the 50 s-70 s age groups. Likewise, the ADC value was significantly higher in the 50 s-70 s age groups. The CST in the brain of normal subjects degenerated continuously from the 20 s to the 70 s, with a near-linear pattern, and degeneration of the CST began to manifest significantly in the subjects in their 50 s, compared with the subjects in their 20 s.

关键词： corticospinal tract motor function aging diffusion tensor imaging

Recommendation application for video head impulse test based on fuzzy logic control

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Journal of Central South University 2016年第5期23卷 1208-1214页

作者： NGUYEN Thi Anh Dao KIM Dae Young LEE Sang min KIM Kyu Sung Seong Ro Lee KWON jang Woo Department of Computer and Information Engineering Inha University Department of Otorhinolaryngology Inha University Hospital Department of Electronic Engineering Inha University Department of Information and Electronics Engineering Mokpo National University

Vestibulo-ocular reflex(VOR) is an important biological reflex that controls eye movement to ensure clear vision while the head is in ***,VOR measurement is commonly done with a video head impulse test based on a velocity gain algorithm or a position gain algorithm,in which velocity gain is a VOR calculation on head and eye velocity,whereas position gain is calculated from head and eye *** aim of this work is first to compare the two algorithms' performance and to detect covert catch-up saccade,then to propose a stand-alone recommendation application for the patient's *** the first experiment,for ipsilesional and contralesional sides,the calculated position gain(0.94±0.17) is higher than velocity gain(0.84±0.19).Moreover,gain asymmetry of both lesion and intact sides using velocity gain is mostly higher than that from using position gain(four out of five subjects).Consequently,for subjects who have unilateral vestibular neuritis diagnosed from clinical symptoms and a vestibular function test,vestibular weakness is depicted by velocity gain much better than by position *** catch-up saccade and position gain then are used as inputs for recommendation applications.

关键词： vestibulo-ocular response video head impulse velocity gain position gain desaccade

β-Arrestin 2 suppresses the activation of YAP by promoting LATS kinase activity

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Genes & Diseases 2023年第2期10卷 348-351页

作者： minsuh Kim Ji min Kim Eun Jeong Cho Chang Ohk Sung Joon Kim Se Jin jang Asan Institute for Life Sciences Asan Medical CenterSeoul 05505Republic of Korea University of Ulsan College of Medicine Seoul 05505Republic of Korea Department of Pathology Asan Medical CenterSeoul 05505Republic of Korea Graduate School of Medical Science and Engineering KAISTDaejeon 34141Republic of Korea OncoClew Life Science Co. LtdSeoul 05505Republic of Korea

Dysregulation of the Hippo pathway has been frequently identified in various human cancers. The Hippo pathway is a highly complex pathway involving multiple types of proteins, and the activation of YAP by LATS kinase is the final effector step in the transcription process. In this study, we linked the roles of the multifunctional adapter proteins β-arrestins (β-arrestin 1 and 2) in cooperation with other signaling pathways such as GPCR and Wnt to essential cellular functions involved in carcinogenesis, including the regulation of cell proliferation, migration, and differentiation as well as stem cell properties.1 Although β-arrestin 1 and 2 have high structural similarities, they have different roles in carcinogenesis as β-arrestin 1 aids cancer cell survival and metastasis2 and β-arrestin 2 inhibits tumor growth.1 In the Hippo signaling pathway, β-arrestins function as scaffold proteins that mediate the phosphorylation of key molecules, and their association with human cancers is a major research topic. In this study, we demonstrated that β-arrestin 2 inhibits YAP activation through the formation of the β-arrestin 2-LATS-YAP trimeric complex, which results in the promotion of the kinase activity of LATS in cancer cell lines and patient-derived colon cancer organoids.

关键词： cancer carcinogenesis activation

Effects of thickness of Al thermal spray coating for STS 304

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中国有色金属学会会刊：英文版 2009年第4期19卷 925-929页

作者： min-Su HAN Yong-Bin WOO Seok-Cheol KO Young-Jae JEONG Seok-Ki jang Seong-Jong KIM Division of Marine Engineering Mokpo Maritime University Chungnam Regional Innovation Agency Jeonnam Techno Park

Thermal spray coating presents a sacrificial-anode cathodic protection method since differences between the potentials of materials are *** a base metal is exposed to seawater,due to defect in the thermal spray coating,the metal is protected by the sacrificial anodic characteristics of the coating layer because micro-cells formed by the base metal and the thermal spray coating act as cathodes and anodes,*** coating thickness has little effect on the surface morphology of the ***,the electrochemical properties with the increasing of coating thickness present good results.

关键词：涂层厚度热喷涂 STS 金属接触电化学性能保护方法牺牲阳极阳极涂层

Comparison of linac-based fractionated stereotactic radiotherapy and tomotherapy treatment plans for intra-cranial tumors

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Chinese Physics C 2010年第11期34卷 1768-1774页

作者： jang Bo Shim Suk Lee Sam Ju Cho Sang Hoon Lee Juree Kim kwang Hwan Cho Chul Kee min Hyun Do Huh Rena Lee Dae Sik Yang Young Je Park Won Seob Yoon Chul Yong Kim Soo Il Kwon Department of Radiation Oncology College of MedicineKorea University Department of Medical Physics Kyonggi University Department of Radiation Oncology College of MedicineEulji University Department of Radiation Oncology Cheil General Hospital & Women's Healthcare CenterKwandong University College of Medicine Department of Radiation Oncology Soonchunhyang University Boocheon Hospital Department of Radiation Oncology Konyang University Hospital Department of Radiation Oncology Inha University Hospital Department of Radiation Oncology School of MedicineEwha Womans University

This study compares and analyzes stereotactic radiotherapy using tomotherapy and linac-based fractionated stereotactic radiotherapy in the treatment of intra-cranial tumors,according to some *** this study,linac-based fractionated stereotactic radiotherapy and tomotherapy treatment were administered to five patients diagnosed with intra-cranial cancer in which the dose of 18–20 Gy was applied on 3–5 separate *** tumor dosing was decided by evaluating the inhomogeneous index （II） and conformity index （CI）.Also,the radiation-sensitive tissue was evaluated using low dose factors V1,V2,V3,V4,V5,and V10,as well as the non-irradiation ratio volume （NIV）.The values of the II for each prescription dose in the linacbased non-coplanar radiotherapy plan and tomotherapy treatment plan were （0.125±0.113） and （0.090±0.180）,respectively,and the values of the CI were （0.899±0.149） and （0.917±0.114）,*** low dose areas,V1,V2,V3,V4,V5,and V10,in radiation-sensitive tissues in the linac-based non-coplanar radiotherapy plan fell into the ranges 0.3%–95.6%,0.1%–87.6%,0.1%–78.8%,38.8%–69.9%,26.6%–65.2%,and 4.2%–39.7%,respectively,and the tomotherapy treatment plan had ranges of 13.6%–100%,3.5%–100%,0.4%–94.9%,0.2%– 82.2%,0.1%–78.5%,and 0.3%–46.3%,*** the NIV for each organ,it is possible to obtain similar values except for the irradiation area of the brain *** percentages of NIV10%,NIV20%,and NIV30%for the brain stem in each patient were 15%–99.8%,33.4%–100%,and 39.8%–100%,respectively,in the fractionated stereotactic treatment plan and 44.2%–96.5%,77.7%–99.8%,and 87.8%–100%,respectively,in the tomotherapy treatment *** order to achieve higher-quality treatment of intra-cranial tumors,treatment plans should be tailored according to the isodose target volume,inhomogeneous index,conformity index,position of the tumor upon fractionated stereotactic radiosurgery,and radiation dosage for radiation-sensitive tissues.

关键词： fractionated stereotactic radiotherapy tomotherapy treatment plan virtual organ delineation

Solution-processed highly adhesive graphene coatings for corrosion inhibition of metals

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Nano Research 2019年第1期12卷 19-23页

作者： Gi-Cheol Son Deuk-Kyu Hwang Jaewon jang Sang-Soo Chee Kyusang Cho Jae-min Myoung Moon-Ho Ham School of Materials Science and Engineering Gwangju Institute of Science and Technology(GIST)123 Cheomdangwagi-roBuk-guGwangju 61005Republic of Korea Research Institute for Solar and Sustainable Energies Gwangju Institute of Science and Technology(GIST)123 Cheomdangwagi-roBuk-gut Gwangju 61005Republic cf Korea Department of Materials Science and Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul 03722Republic of Korea

The corrosion of metals can be induced by different environmental and operational conditions,and protecting metals from corrosion is a serious concern in many *** developme nt of new materials and/or tech no logies to improve the efficie ncy of anti-corrosi on coati ngs has attracted ren ewed in *** this study,we develop a protective coati ng composed of a bilayer structure of reduced graphe ne oxide(RGO)/graphene oxide(GO)applied to Cu plates by spray-coating and subsequent *** annealing of the GO/Cu plates at 120℃produces a bilayer structure of RGO/GO by the partial reducti on of the spray-coated GO *** in duces superior corrosion resista nee and adhesi on strength compared to those of GO/Cu and RGO/Cu plates because of the hydrophobic n ature of the RGO surface exposed to the surroundings and the formation of Cu-O bonds with the O-based functional groups of *** approach provides a viable and scalable route for using graphene coatings to protect metal surfaces from corrosion.

关键词： graphene metal surface coating corrosion solution process