检索结果-南通市图书馆

In vivo and in vitro study of resorbable magnesium wires for medical implants:Mg purity,surface quality,Zn alloying and polymer coating

引用

journal of Magnesium and Alloys 2024年第6期12卷 2472-2488页

作者： K.Tesar j.Luňácková M.jex M.Žaloudková R.Vrbová M.Bartoš P.Klein L.Vištejnová j.dušková E.Filová Z.Sucharda M.Steinerová S.Habr K.Balík A.Singh department of Materials Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueTrojanova 13Prague 12000Czech Republic Institute of Physics Czech Academy of SciencesNa Slovance 2Prague 18221Czech Republic Institute of dental Medicine First Faculty of MedicineCharles University and General University Hospital in PragueKaterinská32Prague 12801Czech Republic department of Physics Faculty of Nuclear Sciences and Physical EngineeringCzech Technical University in PragueBrehová7Prague 11519Czech Republic department of Composites and Carbon Materials Institute of Rock Structure and MechanicsCzech Academy of SciencesV Holešovickách 41Prague 18209Czech Republic Institute of Anatomy First Faculty of MedicineCharles UniversityU Nemocnice 3Prague 12800Czech Republic Biomedical Center Faculty of Medicine in PilsenCharles UniversityAlej Svobody 76Pilsen 32300Czech Republic department of Pathological Physiology Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic department of Histology and Embryology Faculty of Medicine in PilsenCharles UniversityAlej Svobody 7632300 PilsenCzech Republic Institute of Pathology First Faculty of MedicineCharles University and General University Hospital in PragueStudnickova 2Prague 12800Czech Republic department of Biomaterials and Tissue Engineering Institute of PhysiologyCzech Academy of SciencesVidenska 1083Prague 14200Czech Republic Research Center for Structural Materials National Institute for Materials Science1-2-1 SengenTsukuba 305-0047Japan

Magnesium is an excellent material in terms of biocompatibility and its corrosion products can serve as an active source for new bone ***,localized corrosion and H_(2)generation limit the potential of Mg-based *** low-alloyed Mg-Zn wires can strongly reduce problems with large H_(2)bubbles and improve the mechanical properties considerably while maintaining excellent long-term *** pickling and a polymer coating can be effectively used to lower the rate of in vivo *** this work,microstructural,mechanical,and in vitro characterization of 250μm and 300μm extruded wires made from ultra-pure Mg,commercially pure Mg,Mg-0.15Zn,Mg-0.4Zn and Mg-1Zn was ***,Mg-0.4Zn wires together with a variant coated with a copolymer of L-lactide andε-caprolactone were tested in vivo on artificially damaged Wistar rat *** on the observed Mg-induced osteogenesis,polymer-coated Mg wires with a small addition of Zn are a perspective material for bone-support applications,such as cerclage and fixation wires.

关键词： Magnesium Resorbable Mg wire Mg-Zn implant degradation Biocompatibility study Zn grain boundary segregation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

MicroRNA-630:A promising avenue for alleviating inflammation in diabetic kidney disease

引用

World journal of diabetes 2024年第7期15卷 1398-1403页

作者： javier donate-Correa Ainhoa González-Luis jésica díaz-Vera juan Ramón Hernandez-Fernaud Research Unit University Hospital Nuestra Señora de Candelaria(UHNSC)Santa Cruz de Tenerife 38010Spain department of Biochemistry MicrobiologyCell Biology and GeneticsInstituto de Tecnologías BiomédicasUniversidad de La LagunaSanta Cruz de Tenerife 38000Spain

diabetic kidney disease(dKd)is one of the complications of diabetes,affecting millions of people *** relentless progression of this condition can lead to kidney failure,requiring life-altering interventions such as dialysis or *** evidence suggests that immunologic and inflammatory elements play an important role in initiating and perpetuating the damage inflicted on renal tissues,exacerbating the decline in organ ***-like receptors(TLRs)are a family of receptors that play a role in the activation of the innate immune system by the recognition of pathogen-associated molecular *** data from in vitro and in vivo studies have highlighted the critical role of TLRs,mainly TLR2 and TLR4,in the pathogenesis of *** the diabetic milieu,these TLRs recognize diabetic-associated molecular signals,triggering a proinflammatory cascade that initiates and perpetuates inflammation and fibrogenesis in the diabetic *** non-traditional strategies targeting TLR signaling with potential therapeutic implications in dKd have been *** of these approaches is the use of microRnas,small non-coding Rnas that can regulate gene *** editorial comments on the results of this approach carried out in a rat model of diabetes by Wu et al,published in this issue of the World journal of *** results of the experimental study by Wu et al shows that microRNA-630 decreased levels compared to non-diabetic ***,microRNA-630 exerted anti-inflammatory effects in the kidneys of diabetic rats through the modulation of *** findings indicate that the microRNA-630/TLR4 axis might represent a pathological mechanism of dKd and a potential therapeutic target capable of curbing the destructive inflammation characteristic of dKd.

关键词： diabetes diabetic kidney disease Inflammation Toll-like receptor 4 microRNA-630

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Upcycling the spent graphite/LiCoO_(2) batteries for high-voltage graphite/LiCoPO_(4)-co-workable dual-ion batteries

引用

International journal of Minerals,Metallurgy and Materials 2024年第7期31卷 1745-1751页

作者： Miao du Hongyan Lü Kaidi du Shuohang Zheng Xiaotong Wang Xiaotong deng Ronghua Zeng Xinglong Wu Key Laboratory for UV Light-Emitting Materials and Technology of Ministry of Education Northeast Normal UniversityChangchun 130024China Faculty of Chemistry Northeast Normal UniversityChangchun 130024China School of Chemistry South China Normal UniversityGuangzhou 510006China

The worldwide proliferation of portable electronics has resulted in a dramatic increase in the number of spent lithium-ion batteries(LIBs).However,traditional recycling methods still have limitations because of such huge amounts of spent ***,we proposed an ecofriendly and sustainable double recycling strategy to concurrently reuse the cathode(LiCoO_(2))and anode(graphite)materials of spent LIBs and recycled LiCoPO_(4)/graphite(RLCPG)in Li^(+)/PF^(-)_(6) co-de/intercalation dual-ion *** recycle-derived dualion batteries of Li/RLCPG show impressive electrochemical performance,with an appropriate discharge capacity of 86.2 mAh·g^(-1) at25 mA·g^(-1) and 69%capacity retention after 400 *** recycling of the cathode and anode from spent LIBs avoids wastage of resources and yields cathode materials with excellent performance,thereby offering an ecofriendly and sustainable way to design novel secondary batteries.

关键词： recycle lithium cobalt oxide lithium cobalt phosphate graphite dual-ion batteries spent lithium-ion batteries

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A photogrammetric approach for quantifying the evolution of rock joint void geometry under varying contact states

引用

International journal of Mining Science and Technology 2024年第4期34卷 461-477页

作者： Rui Yong Changshuo Wang Nick Barton Shigui du Institute of Rock Mechanics Ningbo UniversityNingbo 315211China Nick Barton&Associates Fjordveien 65cHøvik 1363Norway

Accurate measurement of the evolution of rock joint void geometry is essential for comprehending the distribution characteristics of asperities responsible for shear and seepage ***,existing techniques often require specialized equipment and skilled operators,posing practical *** this study,a cost-effective photogrammetric approach is ***,local coordinate systems are established to facilitate the alignment and precise quantification of the relative position between two halves of a rock ***/pull tests are conducted on rock joints with varying roughness levels to induce different contact states.A high-precision laser scanner serves as a benchmark for evaluating the photogrammetry *** certain deviations exist,the measured evolution of void geometry is generally consistent with the qualitative findings of previous *** photogrammetric measurements yield comparable accuracy to laser scanning,with maximum errors of 13.2%for aperture and 14.4%for void *** joint matching coefficient(jMC)measurement errors are below 20%.Larger measurement errors occur primarily in highly mismatched rock joints with jMC values below 0.2,but even in cases where measurement errors exceed 80%,the maximum jMC error is only ***,the proposed photogrammetric approach holds promise for widespread application in void geometry measurements in rock joints.

关键词： Rock joint Void geometry evolution Photogrammetry Aperture Void volume joint matching coefficient

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Palmitoleic acid on top of HFd ameliorates insulin resistance independent of diacylglycerols and alters gut microbiota in C57BL/6j mice

引用

Food Science and Human Wellness 2024年第2期13卷 856-868页

作者： Qijian Liang Yan Zheng Fanli Meng Xiaofan jiang Qingcai Zhen Zhongting Lu Shixiu Zhang Lei du Hao Wu Xin Guo department of Nutrition and Food Hygiene School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012China Research Center of Translational Medicine Jinan Central Hospital Affiliated to Shandong First Medical UniversityJinan 250013China department of Hepatology Qilu Hospital of Shandong UniversityJinan 250012China Institute of Hepatology Shandong UniversityJinan 250012China

With the prevalence of obesity and obesity-related metabolic syndrome,such as insulin resistance in recent years,it is urgent to explore effective interventions to prevent the progression of obesity-related metabolic *** acid is a monounsaturated fatty acid that is available from dietary sources,mainly derived from marine products.P almitoleic acid plays a positive role in maintaining glucose homeostasis and reducing ***,it is still unknow the mechanism of palmitoleic acid in ameliorating insulin ***,we investigated the effects of palmitoleic acid on chow diet(Cd)-fed and high-fat diet(HFd)-fed mice,which were fed Cd or HFd for 12 weeks before *** administrated mice with BSA(control),oleic acid,or palmitoleic acid for 6 weeks on top of Cd or HFd *** found that palmitoleic acid only improved glucose homeostasis in HFd-fed obese mice by increasing glucose clearance and reducing *** study explored that palmitoleic acid changed the composition of gut microbiota by decreasing Firmicutes population and increasing Bacteroidetes *** colon,palmitoleic acid increased intestinal tight junction integrity and reduced ***,palmitoleic acid decreased macrophage infiltration in liver and adipose tissue and increase glucose uptake in adipose ***(dAG)in tissue(for example,liver)is found to positively correlated with *** enhanced the levels of dAGs in liver but not in adipose tissue in this *** acid did not reverse the high dAG levels induced by HFd in ***,in HFd-fed mice,palmitoleic acid reduced insulin resistance by an independent-manner of *** might be associated with the beneficial effects of palmitoleic acid on altering the gut microbiota composition,improving of intestinal barrier function,and downregulating the inflammation in colon,liver,and adipose tissue.

关键词： Palmitoleic acid High fat diet Insulin resistance Gut microbiota

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nonlinear uncertainty impact of geometric variations on aerodynamic performance of low-pressure turbine blades with ultra-high loading under extreme operational conditions

引用

Chinese journal of Aeronautics 2024年第5期37卷 281-300页

作者： Xiaojing WANG Zhengping ZOU Chao FU Pengcheng du School of Energy and Power Engineering Beihang UniversityBeijing 100191China National Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics Beihang UniversityBeijing 100191China Research Institute of Aero-Engine Beihang UniversityBeijing 100191China

Uncertainty impact of random geometric variations on the aerodynamic performance of low-pressure turbine blades is considerable,which is further amplified by the current ultra-high-lift design trend for weight ***,this uncertainty impact on ultra-highly loaded blades under extreme operational conditions near the margins with potential large-scale open separation is focused on in this *** is demonstrated that this impact is significant,unfavourable,and nonlinear,which is clearly severer under extreme *** addition to the overall attenuation and notable scattering of specific performance,the operational margins with open separation are also notably scattered with great risk of significant *** scattering and nonlinearity are dominated by the variations in leading-edge *** thinning of leading edge triggers local transition,enhancing downstream friction and reducing resistance to open separation,which is further exacerbated by operational ***,the opposite thickening yields less benefit,implying *** unfavourable impact highlights the need for robust aerodynamic design,where both a safer operational condition and a more robust blade are indispensable,i.e.,a compromise among performance,weight,and *** the necessary limitation of loading levels,a mid-loaded design is recommended to reduce adverse pressure gradients in both the leading edge and rear region of the suction side,which helps to decrease the susceptibility of the transition and open separation to random *** improvements can also be achieved by appropriately thickening the leading edge.

关键词： Ultra-highly loaded turbine blade Geometric variations Uncertainty analysis Operational margins Robust aerodynamic design Nonlinearity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Influence of Vanes and Blades on Ingress in Axial Rim Seal for Turbine Stages

引用

journal of Thermal Science 2024年第3期33卷 833-846页

作者： REN Ran du Qiang LIU Guang ZENG Yanlian XIE Lei Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing100190China National Key Laboratory of Science and Technology on Advanced Light-duty Gas-turbine Beijing100190China School of Aeronautics and Astronautics University of Chinese Academy of SciencesBeijing100190China

Hot gas ingestion refers to the phenomenon of mainstream hot gas flowing into the space cavity of a turbine *** studies have found that mainstream annulus pressure distribution plays an important role in hot gas ingestion,but due to its complexity,the mechanism of the interaction between mainstream flow and hot gas ingestion remains *** paper adopts the URANS method,and three sealing flow rates are considered,named C_(w)=0,C_(w)=500,and C_(w)=*** time-averaged annulus pressure distribution shows that an increase in the sealing flow decreases the pressure value,and the effects of the sealing flow on the pressure distribution of the leading edge of the blade are much more influential than that of the trailing edge of the *** unsteady pressure time-space distribution in the annulus indicates that a time-space tilted distribution of pressure at the rim exits when the sealing flow *** phenomenon is mainly due to the strong feedback mechanism of the sealing flow to the annulus pressure field.A comparison of the pressure and mean radial velocity distribution of the mainstream shows that the ingestion mainly occurs on the blade side,where the pressure is lower than on the vane *** flow characteristics at the wheel rim are analyzed with a sealing flow rate C_(w)=5000,and under these conditions,both pressure-induced ingestion and ingestion caused by a passage vortex can be *** three-dimensional and inertial effects of the mainstream at the wheel rim lead to the generation of separation vortices on the blade side,and the presence of separation vortices leads to ingestion along the blade *** the same time,pressure on the blade side will cause the fluid to have a radial inward flow tendency,which will promote the formation of separation vortices,leading to more serious ingestion in the high-pressure region on the blade *** blade pressure field can be more significant than the vane trailing pressure field in the rim sea

关键词： separation vortex unsteady rim seal the effect of blade on ingestion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Body-force modeling considering induced upstream effects for a transonic compressor with total temperature distortion

引用

Chinese journal of Aeronautics 2024年第6期37卷 7-19页

作者： jiahui QIU Chen YANG Wenqiang ZHANG Min ZHANG juan du digital Twin Research Center Institute of Engineering ThermophysicsChinese Academy of SciencesBeijing 100190China School of Engineering and Science University of Chinese Academy of SciencesBeijing 100190China National Key Laboratory of Science and Technology on Advanced Light-duty Gas-turbine Chinese Academy of SciencesBeijing 100190China School of Mechatronical Engineering Beijing Institute of TechnologyBeijing 100081China

To numerically study the impact of total temperature distortion on a transonic compressor with reduced computational costs,a Body-Force Model(BFM)is ***,the interactions between the distorted flow and the compressor are analyzed using full-annulus Unsteady Reynolds-Averaged Navier-Stokes(URANS)results and the orbit *** is found that the induced swirl distortion and the mass flux nonuniformity are intensified in the compressor upstream flow field.A correction factor is thus added to the BFM to account for the effect of the induced swirl,which is crucial for the accurate representation of distortion transfer in the ***,steady simulations with large-amplitude 180circumferential total temperature distortion are performed using the developed *** is shown that the distorted compressor map simulated with the BFM matches well with URANS *** circumferential phase shift of total temperature and the generation of the additional total pressure distortion across the rotor are in line with the time-averaged URANS flow *** compressor upstream effects on the distorted inflow can also be exactly *** above-mentioned results demonstrate the BFM developed in this paper can effectively capture the distorted flow features inside the compressor,and significantly reduce the computational costs by five orders of magnitude compared with URANS.

关键词： Upstream effect Orbit method Induced swirl distortion Body force model Correction factor Time-averaged URANS

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Kinetics of glyphosate and aminomethylphosphonic acid sorption onto montmorillonite clays in soil and their translocation to genetically modified corn

引用

journal of Environmental Sciences 2024年第1期135卷 669-680页

作者： Meichen Wang Kelly j Rivenbark Timothy d Phillips Veterinary Physiology and Pharmacology College of Veterinary Medicine and Biomedical SciencesTexas A&M UniversityTX 77845USA

The co-occurrence of glyphosate(GLP)and aminomethylphosphonic acid(AMPA)in contaminated water,soil,sediment and plants is a cause for concern due to potential threats to the ecosystem and human health.A major route of exposure is through contact with contaminated soil and consumption of crops containing GLP and AMPA ***,clay-based sorption strategies for mixtures of GLP and AMPA in soil,plants and garden produce have been very *** this study,in vitro soil and in vivo genetically modified corn models were used to establish the proof of concept that the inclusion of clay sorbents in contaminated soils will reduce the bioavailability of GLP and AMPA in soils and their adverse effects on plant *** of chemical concentration(1–10 mg/kg),sorbent dose(0.5%-3%in soil and 0.5%-1%in plants)and duration(up to 28 days)on sorption kinetics were *** time course results showed a continuous GLP degradation to *** inclusion of calcium montmorillonite(CM)and acid processed montmorillonite(APM)clays at all doses significantly and consistently reduced the bioavailability of both chemicals from soils to plant roots and leaves in a dose-and time-dependent manner without detectable *** treated with 0.5%and 1%APM inclusion showed the highest growth rate(p≤0.05)and lowest chemical bioavailability with up to 76%reduction in roots and57%reduction in *** indicated that montmorillonite clays could be added as soil supplements to reduce hazardous mixtures of GLP and AMPA in soils and plants.

关键词： Glyphosate AMPA Adsorption Soil remediation Plant Hydroponic system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Generalized polynomial chaos expansion by reanalysis using static condensation based on substructuring

引用

Applied Mathematics and Mechanics(English Edition) 2024年第5期45卷 819-836页

作者： d.LEE S.CHANG j.LEE department of Automotive Engineering Hanyang UniversitySeoul 04763Republic of Korea School of Mechanical Engineering Chungnam National UniversityDaejeon 34134Republic of Korea department of Mechanical Robotics and Energy EngineeringDongguk UniversitySeoul 04620Republic of Korea

This paper presents a new computational method for forward uncertainty quantification(UQ)analyses on large-scale structural systems in the presence of arbitrary and dependent random *** method consists of a generalized polynomial chaos expansion(GPCE)for statistical moment and reliability analyses associated with the stochastic output and a static reanalysis method to generate the input-output data *** the reanalysis,we employ substructuring for a structure to isolate its local regions that vary due to random *** allows for avoiding repeated computations of invariant substructures while generating the input-output data *** substructuring with static condensation further improves the computational efficiency of the reanalysis without losing ***,the GPCE with the static reanalysis method can achieve significant computational saving,thus mitigating the curse of dimensionality to some degree for UQ under high-dimensional *** numerical results obtained from a simple structure indicate that the proposed method for UQ produces accurate solutions more efficiently than the GPCE using full finite element analyses(FEAs).We also demonstrate the efficiency and scalability of the proposed method by executing UQ for a large-scale wing-box structure under ten-dimensional(all-dependent)random inputs.

关键词： forward uncertainty quantification(UQ) generalized polynomial chaos expansion(GPCE) static reanalysis method static condensation substructuring

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：