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Warigal小麦叶绿体类囊体膜的超分子结构

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journal of Integrative Plant Biology 1986年第1期 11-19+119-121页

作者：左宝玉 David j.simpson john V.Possingham 中国科学院植物研究所光合作用研究室 CSIRO Division of Horticulture Research

将Warigal小麦的旗叶和用作对比的第一叶,制作叶绿体类囊体膜的冰冻撕裂旋转投影复型,经电镜观察和电子计算机测量、作图、计算和对比分析。结果发现,旗叶叶绿体类囊体膜四个撕裂面上的冰冻撕裂颗粒,其超分子结构与该小麦第一叶的叶绿... 详细信息

将Warigal小麦的旗叶和用作对比的第一叶,制作叶绿体类囊体膜的冰冻撕裂旋转投影复型,经电镜观察和电子计算机测量、作图、计算和对比分析。结果发现,旗叶叶绿体类囊体膜四个撕裂面上的冰冻撕裂颗粒,其超分子结构与该小麦第一叶的叶绿体类囊体膜上相对应的各撕裂面相比,除了旗叶中垛叠的类囊体膜比第一叶的多约5%以外,其它如在颗粒的大小、密度、颗粒大小的分布和构型等超分子结构上均存在着明显的差异,且优于第一叶的。其中,最引人注目的是在小麦旗叶的叶绿体类囊体膜中,呈现的冰冻撕裂颗粒比第一叶的多。如PFs面上多约22%;EFs面上多约15%;PFu面上多约5%及EFu面上多约28%。从而在结构上,为小麦旗叶的高光效提供了进一步的理论依据。

关键词： Warigal小麦旗叶叶绿体类囊体膜冰冻撕裂旋转投影电子计算机超分子结构

Low-protein diet accelerates wound healing in mice post-acute injury

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Burns & Trauma 2021年第1期9卷 339-350页

作者： jonathan j.Hew Roxanne j.Parungao Craig P.Mooney julian K.Smyth Sarah Kim Kevin H.-Y.Tsai Huaikai Shi Cassandra Chong Renee C.F.Chan Beba Attia Caroline Nicholls Zhe Li Samantha M.Solon-Biet David G.Le Couteur Stephen j.simpson Marc G.jeschke Peter K.Maitz Yiwei Wang Burns Research and Reconstructive Surgery ANZAC Research InstituteConcord HospitalUniversity of SydneySydneyAustralia 2139 Bone Biology Group ANZAC Research InstituteConcord HospitalUniversity of SydneySydneyAustralia 2139 Adrenal Steroids Laboratory ANZAC Research InstituteConcord HospitalUniversity of SydneySydneyAustralia 2139 Electron Microscopy Unit Anatomical PathologyConcord HospitalSydneyAustralia 2139 Burns Unit Concord Repatriation General HospitalConcordAustralia 2139 Ageing and Alzheimer Institute and ANZAC Research Institute Concord HospitalUniversity of SydneySydneyAustralia 2139 Charles Perkins Centre and School of Life and Environmental Sciences University of SydneyAustralia 2006 Sunnybrook Research Institute TorontoOntarioCanadaM4N 3M5 School of Pharmacy Nanjing University of Chinese MedicineNanjingPR China 210023

Background:Wound healing processes are influenced by macronutrient intake(protein,carbohydrate and fat).The most favourable diet for cutaneous wound healing is not known,although highprotein diets are currently favoured *** experimental study investigates the optimal macronutrient balance for cutaneous wound healing using a mouse model and the Geometric Framework,a nutrient modelling method,capable of analyzing the individual and interactive effects of a wide spectrum of macronutrient ***:Two adjacent and identical full-thickness skin excisions(1 cm^(2))were surgically created on the dorsal area of male C57BL/6 *** were then allocated to one of 12 high-energy diets that varied in protein,carbohydrate and fat *** select diets,wound healing processes,cytokine expression,energy expenditure,body composition,muscle and fat reserves were ***:Using the Geometric Framework,we show that a low-protein intake,coupled with a balanced intake of carbohydrate and fat is optimal for wound *** fed a low-protein diet progressed quickly through wound healing stages with favourable wound inflammatory cytokine expression and significantly accelerated collagen *** local processes were associated with an increased early systemic inflammatory response and a higher overall energy expenditure,related to metabolic changes occurring in key macronutrient reserves in lean body mass and fat ***:The results suggest that a low-protein diet may have a greater potential to accelerate wound healing than the current clinically used high-protein diets.

关键词： Wound healing Macronutrients Cutaneous Geometric Framework Mouse model Low-protein diet Nutrition

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轻稀土区Nd和Ce核的超形变带

高能物理与核物理 1989年第7期13卷 632-641页

作者：罗亦孝钟纪泉 A.Kirwan D.j.G.Love P.j.Nolan R.Wadsworth P.j.Bishop M.j.Godfrey R.Hughes A.N.james I.jenkins S.M.Mullins j.simpson D.j.Thornley K.L.Ying 中国科学院近代物理研究所 Oliver Lodge Lab. University of Liverpool PO Box 147 Liverpool L69 3BX U. K. SERC Daresbury Lab. Warrington W A4 4AD U. K. Department of Physics University of York Heslington York Y01 5DD U. K.

轻稀土区高自旋超形变的系统实验研究,首次发现了~133,134,137)Nd和^(131)Ce的超形变带,并证实和进一步研究了前已发现的^(135,136)Nd和^(132)Ce超形变带.本文叙述超形变带的实验寻找、指定和测量,并对所发现的超形变带的馈入、退激、... 详细信息

轻稀土区高自旋超形变的系统实验研究,首次发现了~133,134,137)Nd和^(131)Ce的超形变带,并证实和进一步研究了前已发现的^(135,136)Nd和^(132)Ce超形变带.本文叙述超形变带的实验寻找、指定和测量,并对所发现的超形变带的馈入、退激、转动惯量、相对强度和结构的系统性进行了讨论.

关键词：轻稀土区原子核超形变带钕铈

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用微波炉测光速

今日科苑 2011年第1期 75-75页

作者： Robert j.simpson

研究恒星形成的天文学家会使用望远镜在可见光波段上来观测星云。在星云的内部,温度非常低的尘埃会发出亚毫米波和微波辐射。在电磁波谱上微波处于无线电波和红外光之间,波长范围在1毫米到30厘米。你家的厨房中也许就放着一台微波炉,因... 详细信息

研究恒星形成的天文学家会使用望远镜在可见光波段上来观测星云。在星云的内部,温度非常低的尘埃会发出亚毫米波和微波辐射。在电磁波谱上微波处于无线电波和红外光之间,波长范围在1毫米到30厘米。你家的厨房中也许就放着一台微波炉,因此在日常生活中你可能对它已经相当熟悉了。微波炉会使用特定频率的微波来激发水分子。

关键词：微波炉食物水分子光速微波灶厨房电器棉花糖驻波立波波浪

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质子发射核151Lu的衰变研究

质子发射核151Lu的衰变研究

Role of inflammation and infection in the pathogenesis of human acute liver failure: clinical implications for monitoring and therapy

第十五届全国核结构大会

作者： F.Wang B.Sun Z.Liu C.Scholey S.F.Ashley L.Bianco D.M.Cullen I.j.Cullen I.G.Darby S.Eeckhaudt A.B.Garnsworthyand W.Gelletly M.B.Gomez-Hornillos T.Grahn P.T.Greenlees D.G.jenkins G.A.jones P.jones D.T.joss R.julin S.juutinen S.Kettelhut S.Khan A.Kishada M.Leino M.Niikura M.Nyman R.D.Page j.Pakarinen S.Pietri Z.Podolyak P.Rahkila S.Rigby j.Saren T.Shizuma j.simpson j.Sorri S.Steer N.j.Thompson j.Uusitalo P.M.Walker S.Williams School of Physics and Nuclear Energy Engineering Beihang University Institute of Modern Physics Chinese Academy of Sciences Department of Physics University of Surrey Guildford Surrey GU2 7XH UK Department of Physics University of JyvaskylaJyvaskyla FI-40014 Finland Department of Physics University of Manchester Manchester M13 9PL UK

质子发射核为研究质子滴线附近的核结构提供了重要信息[1]。1981年,在德国GSI的SHIP的速度选择器上,发现了第一个基态质子发射核151Lu。近期又发现151Lu存在一个短寿命的低自旋同核异能态。基于WKB和DWBA理论,简单估计球形核的h11/2和d...

质子发射核为研究质子滴线附近的核结构提供了重要信息[1]。1981年,在德国GSI的SHIP的速度选择器上,发现了第一个基态质子发射核151Lu。近期又发现151Lu存在一个短寿命的低自旋同核异能态。基于WKB和DWBA理论,简单估计球形核的h11/2和d3/2带,可以得到基态为Ep=1223ke V,t1/2=280ms以及同核异能态Ep=1310ke V,t1/2=16μs[2-4]。151Lu激发态的首次跃迁测量是在橡树

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World journal of Gastroenterology 2016年第26期22卷 5958-5970页

作者： Mhairi C Donnelly Peter C Hayes Kenneth j.simpson Department of Hepatology and Scottish Liver Transplant Unit Royal Infirmary of Edinburgh

Acute liver failure is a rare and devastating clinical condition. At present, emergency liver transplantation is the only life-saving therapy in advanced cases, yet the feasibility of transplantation is affected by the presence of systemic inflammation, infection and resultant multiorgan failure. The importance of immune dysregulation and acquisition of infection in the pathogenesis of acute liver failure and its associated complications is now recognised. In this review we discuss current thinking regarding the role of infection and inflammation in the pathogenesis of and outcome in human acute liver failure, the implications for the management of such patients and suggest directions for future research.

关键词： Inflammation Neuroinflammation Acute liver failure Biomarker Infection

A Note on the Relationship Between Temperature and Water Vapor over Oceans, Including Sea Surface Temperature Effects

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Advances in Atmospheric Sciences 2006年第1期23卷 141-148页

作者： C.-L. SHIE W.-K. TAO j. simpson Goddard Earth Sciences and Technology Center University of MarylandBaltimore CountyBaltimoreMaryland 21250USA Laboratory for AtmospheresNASA Goddard Space Flight CenterGreenbeltMaryland 20771USA Laboratory for Atmospheres NASA Goddard Space Flight CenterGreenbeltMaryland 20771USA

An ideal and simple formulation is successfully derived that well represents a quasi-linear relationship found between the domain-averaged water vapor, Q （ram）, and temperature, T （K）, fields for the three tropical oceans （i.e., the Pacific, Atlantic and Indian Oceans） based on eleven GEOS-3 [Goddard Earth Observing System （EOS） Version-3] global re-analysis monthly products. A Q - T distribution analysis is also performed for the tropical and extra-tropical regions based on in-situ sounding data and numerical simulations [GEOS-3 and the Goddard Cumulus Ensemble （GCE） model]. A similar positively correlated Q - T distribution is found over the entire oceanic and tropical regions; however, Q increases faster with T for the former region. It is suspected that the tropical oceans may possess a moister boundary layer than the Tropics. The oceanic regime falls within the lower bound of the tropical regime embedded in a global, curvilinear Q - T relationship. A positive correlation is also found between T and sea surface temperature （SST）; however, for one degree of increase in T, SST is found to increase 1.1 degrees for a warmer ocean, which is slightly less than an increase of 1.25 degrees for a colder ocean. This seemingly indicates that more （less） heat is needed for an open ocean to maintain an air mass above it with a same degree of temperature rise during a colder （warmer） season [or in a colder （warmer） region]. Q and SST are also found to be positively correlated. Relative humidity （RH） exhibits similar behaviors for oceanic and tropical regions. RH increases with increasing SST and T over oceans, while it increases with increasing T in the Tropics. RH, however, decreases with increasing temperature in the extratropics. It is suspected that the tropical and oceanic regions may possess a moister local boundary layer than the extratropics so that a faster moisture increase than a saturated moisture increase is favored for the former regions. T, Q, saturated water v

关键词： moisture temperature relationship quasi-equilibrium states Tropics oceans

Roles for the VCP co-factors Npl4 and Ufd1 in neuronal function in Drosophila melanogaster

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journal of Genetics and Genomics 2017年第10期44卷 493-501页

作者： Dwayne j.Byrne Mark j.Harmon jeremy C.simpson Craig Blackstone Niamh C. O'Sullivan UCD School of Biomolecular and Biomedical Science UCD Conway Institute University College Dublin Dublin 4 Ireland UCD School of Biology and Environmental Science UCD Conway Institute of Biomolecular and Biomedical Research University College Dublin Dublin 4Ireland Cell Biology Section Neurogenetics Branch National Institute of Neurological Disorders and Stroke National Institutes of Health Bethesda MD 20892 USA

The VCP-Ufd1-Npl4 complex regulates proteasomal processing within cells by delivering ubiquitinated proteins to the proteasome for *** in VCP are associated with two neurodegenerative diseases,amyotrophic lateral sclerosis（ALS） and inclusion body myopathy with Paget＇s disease of the bone and frontotemporal dementia（IBMPFD）,and extensive study has revealed crucial functions of VCP within *** contrast,little is known about the functions of Npl4 or Ufd1 in *** neuronalspecific knockdown of Npl4 or Ufd1 in Drosophila melanogaster,we infer that Npl4 contributes to microtubule organization within developing motor ***,Npl4 RNAi flies present with neurodegenerative phenotypes including progressive locomotor deficits,reduced lifespan and increased accumulation of TAR DNA-binding protein-43 homolog（TBPH）.Knockdown,but not overexpression,of TBPH also exacerbates Npl4 RNAi-associated adult-onset neurodegenerative *** contrast,we find that neuronal knockdown of Ufd1 has little effect on neuromuscular junction（NMj） organization,TBPH accumulation or adult *** findings suggest the differing neuronal functions of Npl4 and Ufd1 in vivo.

关键词： Proteasome TDP-43 accumulation Neurodegeneration Drosophila

Identification of isopeptidase activity in the midgut of insects： Purification, properties and nutritional ecology of a Hofmannophila pseudospretella （Lepidoptera： Oecophoridae） larval enzyme

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Insect Science 2010年第4期17卷 325-334页

作者： Robert M. simpson john T. Christeller Plant and Food Research Institute Tennant Drive Palmerston North 4474 Private Bag 11 030 New Zealand

A γ-glutamyl transpeptidase （isopeptidase） has been purified 580-fold to homogeneity from the midgut of keratinophagous larvae of Hofmannophila pseudospretella. The enzyme is a single polypeptide of molecular mass 80 kDa. The enzyme was identified by its hydrolytic activity against the synthetic substrate, γ-glutamyl-AMC, its molecular mass and inhibition profile compared to other γ-glutamyl transpeptidases. The enzyme is low or absent from most other insect digestive systems apart from other keratinophagous lepidopteran larvae and predatory carabids. While isopepfide bonds are present in high levels of the proteins in the diet of keratinophages, their presence in the diet of predatory beetles has not been established.

关键词： γ-glutamyl transpeptidase Hofmannophila pseudospretella isopeptidase,keratinophagous nutritional ecology