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诊断囊性纤维化儿童支气管扩张和气道壁增厚:量化气道-动脉比值的目标

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国际医学放射学杂志 2018年第1期 113-114页

作者： W.Kuo M.de Bruijne j.petersen K.Nasserinejad H.Ozturk Y.Chen 刘晓斌 Department of Pediatric Pulmonology and Allergology Erasmus MC - Sophia Children’s Hospital

摘要目的通过量化囊性纤维化(CF)组和对照组病人的气道-动脉(AA)比值用于诊断支气管扩张和气道壁增厚(AWT)。方法回顾性收集CF组11例和对照组12例,对肺

关键词：气道壁支气管扩张囊性纤维化

用低剂量CT可视化检测持续吸烟者但不包括既往吸烟者的肺气肿进展

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国际医学放射学杂志 2015年第1期 83-83页

作者： M.M.W.Wille L.H.Thomsen A.Dirksen j.petersen j.H.Pedersen S.B.Shaker Department of Respiratory Medicine Gentofte Hospital

目的评价针对肺癌筛查人群采用胸部CT评估肺气肿、气道和间质异常时观察者间一致性和随时间变化的趋势。方法由2名观察者独立评估1 990个参与者的基线和

关键词：肺气肿胸部气道肺疾病躯干吸烟者间质 CT

早期肺气肿和间质病变的影像评估在肺癌危险性分析中是有用的

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国际医学放射学杂志 2016年第2期 216-216页

作者： M.M.W.Wille L.H.Thomsen j.petersen M.Bruijne A.Dirksen j.H.Pedersen 黄杰 Department of Respiratory Medicine Gentofte Hospital

摘要目的应限制高危人群以及在低剂量CT影像中出现有预示肺癌风险的异常表现的人行肺癌筛查。本研究目的观察并比较经筛查的吸烟人群中,患有肺癌和未患肺癌的病人间影像上肺气肿和间质病变发生的情况。材料与方法对1 990名来自丹麦肺癌... 详细信息

摘要目的应限制高危人群以及在低剂量CT影像中出现有预示肺癌风险的异常表现的人行肺癌筛查。本研究目的观察并比较经筛查的吸烟人群中,患有肺癌和未患肺癌的病人间影像上肺气肿和间质病变发生的情况。材料与方法对1 990名来自丹麦肺癌筛查试验的参与者进行低剂量胸部CT检查(尽可能低剂量),并独立评估肺气肿和间质病变两

关键词：肺癌肺肿瘤肺气肿肺疾病间质病变

无通气受限被试最大吸气CT成像吸气过程对气道管径测量的影响

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国际医学放射学杂志 2014年第6期 601-601页

作者： j.petersen M.M.W.Wille L.L.Rakêt A.Feragen j.H.Pedersen M.Nielsen 石彦姝 Department of Computer Science University of CopenhagenN?rre CampusUniversitetsparken 52100 Copenhagen ?Denmark

摘要目的研究志愿者吸气屏气检查中吸气过程对气道直径测量的影响。方法从丹麦肺癌筛查试验中选择961名正常肺活量受试者纳入本研究,所有受试者在5年内每年

关键词：气道支气管吸气过程 CT

Theoretical Analysis of the Fluctuation Theorem Applied to Electric Circuits

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Communications in Theoretical Physics 2014年第10期61卷 476-484页

作者： Charlotte F.petersen Elmars Krausz Denis j.Evans Stephen R.Williams Research School of Chemistry Australian National UniversityCanberraACT 0200Australia

We carry out a theoretical analysis of the fluctuations in the johnson–Nyquist noise in an RC electric circuit being driven by a non-ideal constant current source. Using the appropriate Langevin equation, we derive the fluctuation theorem for the system. This analysis exhibits some interesting features. Firstly, the average of the dissipation function is not necessarily just an instantaneous entropy production, i.e. the work being done on the circuit by the external power source divided by the ambient temperature. Secondly, by appropriate selection of the values for the circuit components,the transient response of the system can be made identical to the nonequilibrium steady state response. In the limit of an ideal current source, the average of the dissipation function reduces to the entropy production. Our analysis accurately reproduces published experimental results.

关键词： circuit analysis fluctuation theorems statistical machanics johnson noise

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Clinical and dietary predictors of common carotid artery intima media thickness in a population with type 1 and type 2 diabetes: A cross-sectional study

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World journal of Diabetes 2017年第1期8卷 18-27页

作者： Kristina S petersen jennifer B Keogh Peter j Meikle Manohar L Garg Peter M Clifton School of Pharmacy and Medical Sciences University of South Australia Baker IDI Heart and Diabetes Institute Nutraceuticals Research Group University of NewcastleCallaghan

AIM To determine the clinical and dietary predictors of common carotid artery intima media thickness(CCA IMT) in a cohort of subjects with type 1 and type 2 diabetes. METHODS Participants with type 1(n = 23) and type 2 diabetes(n = 127) had mean and mean maximum CCA IMT measured using B mode ultrasound. Dietary intake was measured using a food frequency questionnaire. Clinical and dietary predictors of mean and mean maximum CCA IMT were determined using linear regression analysis adjusted for potential confounders. RESULTS The main predictors of mean and mean maximum CCA IMT were age and weight. After multivariate adjustment there were no dietary predictors of CCA IMT. However,in subjects that were not prescribed a lipid lowering medication alcohol consumption was positively associated with CCA IMT after multivariate adjustment. No difference existed in CCA IMT between subjects with type 1 or type 2 diabetes once age was adjusted for. CONCLUSION CCA IMT was predominantly predicted by age and weight in these subjects with diabetes. The finding that CCA IMT was not different between people with type 1 and type 2 diabetes warrants further investigation in a larger cohort.

关键词：糖尿病颈动脉 intima 媒介厚度动脉的结构饮食 Lipidomics 类胡萝卜素

Thermo-mechanical dynamics of nanoimprinting anti-reflective structures onto small-core mid-IR chalcogenide fibers [Invited]

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Chinese Optics Letters 2021年第3期19卷 46-52页

作者： Christian R.petersen Mikkel B.Lotz Christos Markos Getinet Woyessa David Furniss Angela B.Seddon Rafael j.Taboryski O.Bang DTU Fotonik Technical University of DenmarkDK-2800 Kgs.LyngbyDenmark DTU Nanolab Technical University of DenmarkDK-2800 Kgs.LyngbyDenmark NORBLIS DK-2830 VirumDenmark Mid-Infrared Photonics Group University of NottinghamNottingham NG72RDUK NKT Photonics DK-3460 Bi「ke「0dDenmark

Thermal nanoimprinting is a fast and versatile method for transferring the anti-reflective properties of subwavelength nanostructures onto the surface of highly reflective substrates, such as chalcogenide glass optical fiber end faces. In this paper, the technique is explored experimentally on a range of different types of commercial and custom-drawn optical fibers to evaluate the influence of geometric design, core/cladding material, and thermo-mechanical properties. Up to32.4% increased transmission and 88.3% total transmission are demonstrated in the 2–4.3 μm band using a mid-infrared(IR) supercontinuum laser.

关键词： nanoimprint lithography anti-reflection hot imprint chalcogenide glass optical fiber mid-infrared supercontinuum

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Association between dairy intake,lipids and vascular structure and function in diabetes

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World journal of Diabetes 2017年第5期8卷 202-212页

作者： Kristina S petersen jennifer B Keogh Natalie Lister jacquelyn M Weir Peter j Meikle Peter M Clifton School of Pharmacy and Medical Sciences and Sansom Institute for Health Research University of South Australia Baker IDI Heart and Diabetes Institute

AIM To determine lipid species that change in response to a change in dairy consumption. In addition, to investigate whether dairy associated lipid species are correlated with changes in measures of vascular structure and *** A 12-mo randomised controlled trial was conducted to determine the effect of increased consumption of fruit, vegetables and dairy, compared to usual diet, on measures of vascular structure and function in adults with type 1 and type 2 diabetes(n = 108). Thispaper comprises post-hoc analyses investigating the relationship between dairy intake, serum lipid species and vascular health. Central and peripheral blood pressure, carotid femoral pulse wave velocity, augmentation index, serum lipid species and dietary intake were measured at baseline and 3-mo. Common carotid artery intima media thickness was measured at baseline and *** Serum lipid species [lysophosphatidylcholine(LPC) 14:0, LPC 15:0, LPC 16:1, phosphatidylcholine(PC) 29:0 PC 30:0, PC 31:0 and cholesterol ester(CE) 14:0] were associated with the change in full fat dairy consumption(rho 0.19-0.25; P < 0.05). The 3-mo change in some lipids was positively associated with the 3-mo change in central systolic [LPC 14:0(rho 0.30; P = 0.007), PC 30:0(rho 0.28; P = 0.010)] and diastolic blood pressure [LPC 14:0(rho 0.32; P = 0.004), LPC 15:0(rho 0.23; P = 0.04), LPC 16:1(rho 0.23; P = 0.035), PC 29:0(rho 0.28; P = 0.01), PC 30:0(rho 0.36; P = 0.001), PC 31:0(rho 0.30; P = 0.007)] and 12-mo change in common carotid artery intimal medial thickness [CE 14:0(rho 0.22; P = 0.02)]. Pulse wave velocity and augmentation index were unrelated to dairy and lipid *** An increase in dairy associated lipids appears to be associated with an increase in blood pressure and common carotid intimal medial thickness.

关键词： Lipids Phospholipids Atherosclerosis Dairy Lysophosphatidylcholine Lipidomics Carotid intima media thickness Pulse wave velocity Diabetes

Percutaneous transluminal angioplasty balloons for endoscopic ultrasound-guided pancreatic duct interventions

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World journal of Gastrointestinal Endoscopy 2022年第8期14卷 487-494页

作者： jad P AbiMansour Barham K Abu Dayyeh Michael j Levy Andrew C Storm john A Martin Bret T petersen Ryan j Law Mark D Topazian Vinay Chandrasekhara Department of Gastroenterology and Hepatology Mayo ClinicRochesterMN 55905United States

BACKGROUND Endoscopic ultrasound(EUS)-guided main pancreatic duct(PD)access may be used when conventional endoscopic retrograde cholangiopancreatography(ERCP)techniques *** use of a percutaneous transluminal angioplasty balloon(PTAB),originally developed for vascular interventions,can be used to facilitate transmural(e.g.,transgastric)PD access and to dilate high-grade pancreatic *** To describe the technique,efficacy,and safety of PTABs for EUS-guided PD *** Patients who underwent EUS with use of a PTAB from March 2011 to August 2021 were retrospectively identified from a tertiary care medical center supply *** included 3-4 French angioplasty catheters with 3-4 mm balloons designed to use over a 0.018-inch *** primary outcome was technical *** outcomes included incidence of adverse events(AEs)and need for early *** A total of 23 patients were identified(48%female,mean age 55.8 years).Chronic pancreatitis was the underlying etiology in 13(56.5%)patients,surgically altered anatomy(SAA)with stricture in 7(30.4%),and SAA with post-operative leak in 3(13.0%).Technical success was achieved in 20(87%)*** AE rate was 26%(n=6).All AEs were mild and included 1 pancreatic duct leak,2 cases of post-procedure pancreatitis,and 3 admissions for post-procedural *** patients required early *** EUS-guided use of PTABs for PD access and/or stricture management is feasible with an acceptable safety profile and can be considered in patients when conventional ERCP cannulation fails.

关键词： Dilating balloon Pancreatic duct intervention Chronic pancreatitis Anastomotic stricture