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Characterization of acute-on-chronic liver diseases: A multicenter prospective cohort study

World journal of hepatology 2024年第5期16卷 809-821页

作者： Yuan-Yao Zhang Sen luo hai li Shu-Ning sun xian-Bo Wang xin Zheng Yan huang Bei-ling li Yan-hang Gao Zhi-Ping Qian feng liu xiao-Bo lu jun-Ping liu hao-Tang Ren Yu-Bao Zheng hua-Dong Yan Guo-hong Deng liang Qiao Yan Zhang Wen-Yi Gu xiao-Mei xiang Yi Zhou Yi-xin hou Qun Zhang Yan xiong Cong-Cong Zou jun Chen Ze-Bing huang xiu-hua jiang Ting-Ting Qi Yuan-Yuan Chen Na Gao Chun-Yan liu Wei Yuan xue Mei jing li Tao li Rong-jiong Zheng xin-Yi Zhou jun zhao Zhong-ji Meng Department of Infectious Disease Institute of Biomedical ResearchRegulatory Mechanism and Targeted Therapy for Liver Cancer Shiyan Key LaboratoryHubei provincial Clinical Research Center for Precise Diagnosis and Treatment of Liver CancerTaihe HospitalHubei University of MedicineShiyan 442000Hubei ProvinceChina Department of Gastroenterology Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai 200120China Department of Infectious Diseases Southwest HospitalThe Third Military Medical University(Army Medical University)Chongqing 400000China Center of Integrative Medicine Beijing Ditan HospitalCapital Medical UniversityBeijing 100020China Department of Infectious Diseases Institute of Infection and ImmunologyUnion HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430020Hubei ProvinceChina Department of Infectious Diseases Hunan Key Laboratory of Viral HepatitisXiangya HospitalCentral South UniversityChangsha 110051Hunan ProvinceChina hepatology Unit Department of Infectious DiseasesNanfang HospitalSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of hepatology The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of liver Intensive Care Unit Shanghai Public Health Clinical CentreFudan UniversityShanghai 200093China Tianjin Institute of hepatology Nankai University Second People's HospitalTianjin 300192China Infectious Disease Center The First Affiliated Hospital of Xinjiang Medical UniversityUrumqi 830054Xinjiang Uygur Autonomous RegionChina Department of Infectious Diseases and hepatology The Second Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina State Key laboratory for Diagnosis and Treatment of Infectious Diseases Collaborative Innovation Center for Diagnosis and Treatment of Infectious DiseaseThe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310000Zhejiang ProvinceChina Department of Infectious Diseases The Thir

BACKGROUND Acute-on-chronic liver disease(AoClD)accounts for the majority of patients hospitalized in the Department of hepatology or Infectious *** To explore the characterization of AoClD to provide theoretical guidance for the accurate diagnosis and prognosis of *** Patients with AoClD from the Chinese Acute-on-Chronic liver failure(AClf)study cohort were included in this *** clinical characteristics and outcomes,and the 90-d survival rate associated with each clinical type of AoClD were analyzed,using the Kaplan-Meier method and the log-rank *** A total of 3375 patients with AoClD were enrolled,including 1679(49.7%)patients with liver cirrhosis acute decompensation(lC-AD),850(25.2%)patients with AClf,577(17.1%)patients with chronic hepatitis acute exacer-bation(ChAE),and 269(8.0%)patients with liver cirrhosis active phase(lC-A).The most common cause of chronic liver disease(ClD)was hBV infection(71.4%).The most common precipitants of AoClD was bacterial infection(22.8%).The 90-d mortality rates of each clinical subtype of AoClD were 43.4%(232/535)for type-C AClf,36.0%(36/100)for type-B AClf,27.0%(58/215)for type-A AClf,9.0%(151/1679)for lC-AD,3.0%(8/269)for lC-A,and 1.2%(7/577)for *** hBV infection is the main cause of ClD,and bacterial infection is the main precipitant of *** most common clinical type of AoClD is *** diagnosis and timely intervention are needed to reduce the mortality of patients with lC-AD or AClf.

关键词： Acute-on-chronic liver disease Acute-on-chronic liver failure liver cirrhosis Clinical features Prognosis

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Improving constraint onΩ_(m)from SDSS using marked correlation functions

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Science china(Physics,Mechanics & Astronomy) 2024年第8期67卷 207-224页

作者： limin lai jiacheng Ding xiaolin luo Yizhao Yang Zihan Wang Keshi liu Guanfu liu xin Wang Yi Zheng zhaoyu li le Zhang xiao-Dong li School of Physics and Astronomy Sun Yat-sen University Zhuhai CampusZhuhai 519082China Department of Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Department of Astronomy Tsinghua UniversityBeijing 100084China CSST Science Center for the Guangdong-hong Kong-Macao Greater Bay Area SYSUZhuhai 519082China Peng Cheng laboratory Shenzhen 518000China

large-scale structure(lSS)surveys will increasingly provide stringent constraints on our cosmological ***,the density-marked correlation function(MCf)has been introduced,offering an easily computable density-correlation *** have demonstrated that MCfs offer additional,independent constraints on cosmological models beyond the standard two-point correlation(2PCf).In this study,we apply MCfs for the first time to SDSS CMASS data,aiming to investigate the statistical information regarding clustering and anisotropy properties in the Universe and assess the performance of various weighting schemes in MCfs,and finally obtain constraints onΩ_(m).Upon analyzing the CMASS data,we observe that,by combining different weights(α=[-0.2,0,0.2,0.6]),the MCfs provide a tight and independent constraint on the cosmological parameterΩ_(m),yieldingΩ_(m)=0.293±0.006 at the 1σlevel,which represents a significant reduction in the statistical error by a factor of 3.4 compared to that from *** constraint is consistent with recent findings from the small-scale clustering of BOSS galaxies(Zhai et ***.j.948,99(2023))within the 1σ***,we also find that our estimate is lower than the Planck measurements by about 2.6σ,indicating the potential presence of new physics beyond the standard cosmological model if all the systematics are fully *** method outlined in this study can be extended to other surveys and datasets,allowing for the constraint of other cosmological ***,it serves as a valuable tool for forthcoming emulator analysis on the Chinese Space Station Telescope(CSST).

关键词： large scale structure of universe dark energy cosmological parameters marked weighted correlation function

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Spin-conserved PES Calculation:first Application on 178hf

Spin-conserved PES Calculation:First Application on 178Hf

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第十三届全国核结构研讨会暨第九次全国“核结构与量子力学”专题讨论会

作者： C.f.jiao~1 f.R.xu~(1 1)) Y.sun~2 1(School of Physics,and State Key laboratory of Nuclear Physics and Technology,Peking university,Beijing 100871,china) 2(Department of Physics,shanghai jiao tong university,shanghai 200240,People's Republic of china)

A spin-conserved potential-energy-surface（PES） calculation,which takes angular momentum restoration and multi-quasiparticle excitations into account,is developed by using the concepts of the macroscopic-microscopic shell correction and the projected shell model（PSM）.With this method,it may become possible to modify the excitation spectra which are influenced by shape-softness of *** our first example, this method is performed to study the multi-quasiparticle and collective excitations of hf,which are in good agreement with the existing experimental *** addition,the conflict of the dominant structure of 6 band between experimental results and previous PSM calculations is clarified.

关键词： Nuclear structure Potential-energy surface Projected shell model

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The strain rate sensitive and anisotropic behavior of rare-earth magnesium alloy ZEK100 sheet

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journal of Magnesium and Alloys 2023年第3期11卷 882-891页

作者： h.Wang x.sun S.Kurukuri M.j.Worswick D.Y.li Y.h.Peng P.D.Wu State Key laboratory of Mechanical Systems and Vibration Shanghai Jiao Tong UniversityShanghai 200240China Materials Genome Initiative Center Shanghai Jiao Tong UniversityShanghai 200240China Department of Mechanical and Mechatronics Engineering University of WaterlooWaterlooOntario N2L 3G1Canada Department of Mechanical Engineering Mc Master UniversityHamiltonOntario L8S 4L7Canada

To overcome the limitation in formability at room temperature,manufacturers have developed magnesium alloys with remarkable properties by adding rare-earth *** rare-earth magnesium alloys behave differently from the conventional alloys,especially with respect to their coupled anisotropic and strain rate sensitive *** the current work,such behavior of the rare-earth Mg alloy ZEK100 sheet at room temperature is investigated with the aid of the elastic viscoplastic self-consistent polycrystal plasticity *** strain rate sensitivities(SRSs)for various deformation modes are employed by the model to simulate the strain rate sensitive behaviors under different loading directions and loading *** agreement between the experiments and simulations reveals the importance and necessity of using different SRSs for each deformation mode in hexagonal close-packed ***,the relative activities of each deformation mode and the texture evolution during different loadings are *** anisotropic and strain rate sensitive behavior is ascribed to the various operating deformation modes with different SRSs during loading along different directions.

关键词： Rare-earth magnesium alloy Strain rate sensitivity Twinning Crystal plasticity

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Observation of the Crab Nebula with lhAASO-KM2A−a performance study

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Chinese Physics C 2021年第2期45卷 518-530页

作者： f.Aharonian Q.An Axikegu l.x.Bai Y.x.Bai Y.W.Bao D.Bastieri x.j.Bi Y.j.Bi h.Cai j.T.Cai Z.Cao j.Chang j.f.Chang x.C.Chang B.M.Chen j.Chen l.Chen M.j.Chen M.l.Chen Q.h.Chen S.h.Chen S.Z.Chen T.l.Chen x.l.Chen Y.Chen N.Cheng Y.D.Cheng S.W.Cui x.h.Cui Y.D.Cui B.Z.Dai h.l.Dai Z.G.Dai D.della Volpe B.D'Ettorre Piazzoli x.j.Dong j.h.fan Y.Z.fan Z.x.fan j.fang K.fang C.f.feng l.feng S.h.feng Y.l.feng B.Gao C.D.Gao Q.Gao W.Gao M.M.Ge l.S.Geng G.h.Gong Q.B.Gou M.h.Gu j.G.Guo x.l.Guo Y.Q.Guo Y.Y.Guo Y.A.han h.h.he h.N.he j.C.he S.l.he x.B.he Y.he M.heller Y.K.hor C.hou x.hou h.B.hu S.hu S.C.hu x.j.hu D.h.huang Q.l.huang W.h.huang x.T.huang Z.C.huang f.ji x.l.ji h.Y.jia K.jiang Z.j.jiang C.jin D.Kuleshov K.levochkin B.B.li C.li f.li h.B.li h.C.li h.Y.li j.li K.li W.l.li x.li x.R.li Y.li Y.Z.li Z.li E.W.liang Y.f.liang S.j.lin B.liu C.liu D.liu h.liu h.D.liu j.liu j.l.liu j.S.liu j.Y.liu M.Y.liu R.Y.liu S.M.liu W.liu Y.N.liu Z.x.liu W.j.long R.lu h.K.lv B.Q.Ma l.l.Ma x.h.Ma j.R.Mao A.Masood W.Mitthumsiri T.Montaruli Y.C.Nan B.Y.Pang P.Pattarakijwanich Z.Y.Pei M.Y.Qi D.Ruffolo V.Rulev A.Sáiz l.Shao O.Shchegolev x.D.Sheng j.R.Shi h.C.Song Yu.V.Stenkin V.Stepanov Q.N.sun x.N.sun Z.B.sun P.h.T.Tam Z.B.Tang W.W.Tian B.D.Wang C.Wang h.Wang h.G.Wang j.C.Wang j.S.Wang l.P.Wang l.Y.Wang R.N.Wang W.Wang x.G.Wang x.j.Wang x.Y.Wang Y.D.Wang Y.j.Wang Y.P.Wang Z.Wang Z.h.Wang Z.x.Wang D.M.Wei j.j.Wei Y.j.Wei T.Wen C.Y.Wu h.R.Wu S.Wu W.x.Wu x.f.Wu S.Q.xi j.xia j.j.xia G.M.xiang G.xiao h.B.xiao G.G.xin Y.l.xin Y.xing D.l.xu R.x.xu l.xue D.h.Yan C.W.Yang f.f.Yang j.Y.Yang l.l.Yang M.j.Yang R.Z.Yang S.B.Yang Y.h.Yao Z.G.Yao Y.M.Ye l.Q.Yin N.Yin x.h.You Z.Y.You Y.h.Yu Q.Yuan h.D.Zeng T.x.Zeng W.Zeng Z.K.Zeng M.Zha x.x.Zhai B.B.Zhang h.M.Zhang h.Y.Zhang j.l.Zhang j.W.Zhang l.Zhang l.x.Zhang P.f.Zhang P.P.Zhang R.Zhang S.R.Zhang S.S.Zhang x.Zhang x.P.Zhang Y.Zhang Y.f.Zhang Y.l.Zhang B.zhao j.zhao l.zhao l.Z.zhao S.P.zhao f.Zheng Y.Zheng B.Zhou h.Zhou j.N.Zhou P.Zhou R.Zhou x.x.Zhou C.G.Zhu f.R.Zhu h.Zhu K.j.Zhu x.Zuo Key laboratory of Particle Astrophyics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of Sciences100049 BeijingChina university of Chinese Academy of Sciences 100049 BeijingChina TIANfu Cosmic Ray Research Center ChengduSichuanChina State Key laboratory of Particle Detection and Electronics China university of Science and Technology of china 230026 HefeiAnhuiChina Department of Engineering Physics Tsinghua University100084 BeijingChina National Astronomical Observatories Chinese Academy of Sciences100101 BeijingChina National Space Science Center Chinese Academy of Sciences100190 BeijingChina School of Physics Peking University100871 BeijingChina Center for Astrophysics Guangzhou University510006 GuangzhouGuangdongChina School of Physics and Astronomy&School of Physics(Guangzhou) Sun Yat-sen University519000 ZhuhaiGuangdongChina School of Physical Science and Technology Guangxi University530004 NanningGuangxiChina hebei Normal university 050024 ShijiazhuangHebeiChina School of Physics and Microelectronics Zhengzhou University450001 ZhengzhouHenanChina School of Astronomy and Space Science Nanjing University210023 NanjingJiangsuChina Key laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of Sciences210023 NanjingJiangsuChina Institute of frontier and Interdisciplinary Science Shandong University266237 QingdaoShandongChina Key laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of Sciences200030 ShanghaiChina Tsung-Dao lee Institute&School of Physics and Astronomy Shanghai Jiao Tong University200240 ShanghaiChina School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong University610031 ChengduSichuanChina College of Physics Sichuan University610065 ChengduSichuanChina Key laboratory of Cosmic Rays(Tibet university) Ministry of Education850000 LhasaTibetChina School of Physics and Tec

A sub-array of the large high Altitude Air Shower Observatory(lhAASO),KM2A is mainly designed to observe a large fraction of the northern sky to hunt for γ-ray sources at energies above 10 *** though the detector construction is still underway,half of the KM2A array has been operating stably since the end of *** this paper,we present the KM2A data analysis pipeline and the first observation of the Crab Nebula,a standard candle in very high energy γ-ray *** detect γ-ray signals from the Crab Nebula in both energy ranges of 10-100 TeV and>100 TeV with high significance,by analyzing the KM2A data of 136 live days between December 2019 and May *** the observations,we test the detector performance,including angular resolution,pointing accuracy and cosmic-ray background rejection *** energy spectrum of the Crab Nebula in the energy range 10-250 TeV fits well with a single power-law function dN/dE=(1.13±0.05stat±0.08sys)×10^(-14).(E/20 TeV)-309±0.06stat±0.02syscm^(-2) s^(-1) TeV^(-1).It is consistent with previous measurements by other *** opens a new window of γ-ray astronomy above 0.1 PeV through which new ultrahigh-energy γ-ray phenomena,such as cosmic PeVatrons,might be discovered.

关键词： γ-ray Crab Nebula extensive air showers cosmic rays

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linear response Model of Si Single Electron Transistor

Linear response Model of Si Single Electron Transistor

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2001 6～(th) International Conference on Solid-State and Integrated Circuit Technology

作者： S.Zhou, j.f.jiang, and Q.Y.CaiResearch Institute of Micro/Nano Science and Technology, shanghai jiao tong university, shanghai, 200030, P. R. china

linear response model of semiconductor silicon singleelectron transistor(Si-SET)is *** Coulombisland of the Si-SET with a discrete level spectrum isweakly coupled to two electron reservoirs via barriers ofnano-tunneling *** reservoirs,named sourceand drain electrodes respectively,are taken to be inthermal equilibrium at temperature T and fermi *** Si-SET is considered to be driven in linearresponse,i.e.,the conductance G is defined as G=I/V inthe limit V tends to *** analyze the conductancecharacteristics of the Si-SET,which make it possible tosimulate circuit characteristics of the Si-SET fromphysical parameters.

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Universality of quenching-partitioning-tempering local equilibrium model

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journal of Materials Science & Technology 2022年第29期124卷 116-120页

作者： j.Z.Zhang l.Y.Zeng x.W.Zuo j.f.Wan Y.h.Rong N.Min j.lu N.l.Chen Department of Mechanical Engineering City University of Hong KongGreater Bay Joint DivisionShenyang National Laboratory for Materials ScienceTat Chee AvenueKowloonHong KongChina shanghai Key laboratory of Materials laser Processing and Modification School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China laboratory for Microstructures Shanghai UniversityShanghai 201900China CityU-Shenzhen futian Research Institute Shenzhen 518045China

*** As typical 3rd generation advanced high strength steels(AhSSs),quenching and partitioning(Q&P)steel has attracted lots of attention for excellent performance in strength-ductility[1–5].With absorbing carbon partitioning as the core idea of Q&P process,quenching-partitioning-tempering(Q-P-T)process was proposed with emphasis on precipitation strengthening for better combination of strength and ductility[6–10].

关键词： tempering strength ductility

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Study of BESIII trigger efficiencies with the 2018 j/ψ data

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Chinese Physics C 2021年第2期45卷 48-55页

作者： M.Ablikim M.N.Achasov P.Adlarson S.Ahmed M.Albrecht R.Aliberti A.Amoroso M.R.An Q.An x.h.Bai Y.Bai O.Bakina R.Baldini ferroli I.Balossino Y.Ban K.Begzsuren N.Berger M.Bertani D.Bettoni f.Bianchi j.Bloms A.Bortone I.Boyko R.A.Briere h.Cai x.Cai A.Calcaterra G.f.Cao N.Cao S.A.Cetin j.f.Chang W.l.Chang G.Chelkov D.Y.Chen G.Chen h.S.Chen M.l.Chen S.j.Chen x.R.Chen Y.B.Chen Z.j Chen W.S.Cheng G.Cibinetto f.Cossio x.f.Cui h.l.Dai x.C.Dai A.Dbeyssi R.E.de Boer D.Dedovich Z.Y.Deng A.Denig I.Denysenko M.Destefanis f.De Mori Y.Ding C.Dong j.Dong l.Y.Dong M.Y.Dong x.Dong S.x.Du Y.l.fan j.fang S.S.fang Y.fang R.farinelli l.fava f.feldbauer G.felici C.Q.feng j.h.feng M.fritsch C.D.fu Y.Gao Y.Gao Y.Gao Y.G.Gao I.Garzia P.T.Ge C.Geng E.M.Gersabeck A Gilman K.Goetzen l.Gong W.x.Gong W.Gradl M.Greco l.M.Gu M.h.Gu S.Gu Y.T.Gu C.Y Guan A.Q.Guo l.B.Guo R.P.Guo Y.P.Guo A.Guskov T.T.han W.Y.han x.Q.hao f.A.harris h hüsken K.l.he f.h.heinsius C.h.heinz T.held Y.K.heng C.herold M.himmelreich T.holtmann Y.R.hou Z.l.hou h.M.hu j.f.hu T.hu Y.hu G.S.huang l.Q.huang x.T.huang Y.P.huang Z.huang T.hussain W.Ikegami Andersson W.Imoehl M.Irshad S.jaeger S.janchiv Q.ji Q.P.ji x.B.ji x.l.ji h.B.jiang x.S.jiang j.B.jiao Z.jiao S.jin Y.jin T.johansson N.Kalantar-Nayestanaki x.S.Kang R.Kappert M.Kavatsyuk B.C.Ke I.K.Keshk A.Khoukaz P.Kiese R.Kiuchi R.Kliemt l.Koch O.B.Kolcu B.Kopf M.Kuemmel M.Kuessner A.Kupsc M.G.Kurth W.Kühn j.j.lane j.S.lange P.larin A.lavania l.lavezzi Z.h.lei h.leithoff M.lellmann T.lenz C.li C.h.li Cheng li D.M.li f.li G.li h.li h.li h.B.li h.j.li j.l.li j.Q.li j.S.li Ke li l.K.li lei li P.R.li S.Y.li W.D.li W.G.li x.h.li x.l.li Z.Y.li h.liang h.liang h.liang Y.f.liang Y.T.liang l.Z.liao j.libby C.x.lin B.j.liu C.x.liu D.liu f.h.liu fang liu feng liu h.B.liu h.M.liu huanhuan liu huihui liu j.B.liu j.l.liu j.Y.liu K.liu K.Y.liu Ke liu l.liu M.h.liu P.l.liu Q.liu Q.liu S.B.liu Shuai liu T.liu W.M.liu x.liu Y.liu Y.B.liu Z.A.liu Z.Q.liu x.C.lou f.x.lu h.j.lu j.D.lu j.G.lu x.l.lu Y.lu Y.P.lu C.l.luo M.x.luo b P.W.luo T.luo x.l.luo S Institute of high Energy Physics Beijing 100049China Beihang university Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-university D-44780 BochumGermany Carnegie Mellon university PittsburghPennsylvania 15213USA Central china Normal university Wuhan 430079China china Center of Advanced Science and Technology Beijing 100190China COMSATS university Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan fudan university Shanghai 200443China GIBudker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI helmholtzcentre for heavy Ion Research Gmbh D-64291 DarmstadtGermany Guangxi Normal university Guilin 541004China Guangxi university Nanning 530004China hangzhou Normal university Hangzhou 310036China helmholtz Institute Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany henan Normal university Xinxiang 453007China henan university of Science and Technology Luoyang 471003China huangshan College Huangshan 245000China hunan Normal university Changsha 410081China hunan university Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana university BloomingtonIndiana 47405USA (A)INfN laboratori Nazionali di frascati I-00044FrascatiItaly(B)INFN Sezione di PerugiaI-06100PerugiaItaly(C)University of PerugiaI-06100PerugiaItaly (A)INfN Sezione di ferrara I-44122FerraraItaly(B)University of FerraraI-44122FerraraItaly Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Ave54BUlaanbaatar 13330Mongolia jilin university Changchun 130012China johannes Gutenberg university of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia justus-liebig-Universitaet Giessen IIPhysikalisches InstitutHeinrich-Buff-Ring 16D-35392GiessenGermany KVI-CART University of GroningenNL-9747 AA GroningenThe Netherlands lanzhou university Lanzhou 730000China liaoning Normal Unive

Using a dedicated data sample taken in 2018 on the j/ψpeak,we perform a detailed study of the trigger efficiencies of the BESIII *** efficiencies are determined from three representative physics processes,namely Bhabha scattering,dimuon production and generic hadronic events with charged *** combined efficiency of all active triggers approaches 100%in most cases,with uncertainties small enough not to affect most physics analyses.

关键词： BESIII trigger efficiency Bhabha dimuon hadronic events

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Offspring from heterotopic Transplantation of Newborn Mice Ovaries

Offspring from Heterotopic Transplantation of Newborn Mice O...

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第九届中国实验动物科学年会（2010新疆）

作者： S li1~*,B-l Qin2~*.f li1,W-l li2,Z-D Shi2,Y-B Tian3 and x-j Chen1 1 Center for Developmental Biology,xinhua hospital,shanghai jiao tong university,School of Medicine, shanghai,china 2College of Animal Sciences,South china Agricultural university,Guangzhou,china 3Zhongkai College of Agriculture and Technology,Guangzhou,china

Objective Ovarian tissue transplantation was initially described as a means of rescuing endocrine and reproductive functions in women(Oktay and Karlikaya 2000;Oktay et al.2001).for example,fertility loss due to iatrogenic disruption of ovarian function in female oncological patients is expected as a consequence of receiving chemotherapy and/or radiation *** et al.(2004) reported that live births could be achieved using oocytes derived from cryopreserved human ovarian cortical tissues after orthotopic *** technology has offered an important strategy for potentially preserving ***,a similar approach would also be very useful for the conservation of endangered wild animals orrare *** on ovarian tissue transplantation has been ongoing for decades(Parrott 1957,1959a;b),and live mouse offspring have been derived from cryopreserved primordial follicles(Carroll et al.1990;Eppig and O’Brien 1996).Ovarian tissue transplantation has been developed as a simple and highly efficient alternative for obtaining matured *** transplantation of mouse ovaries to the kidney capsule has also been described(Telfer et al.1990).When fertilized in vitro and transferred into surrogate mothers,oocytes derived from transplanted ovarian tissues resulted in a few live offspring(Cox et al.1996;liu et al.2000;lee et al.2004).Recently,liu et *** that live offspring can be obtained from oocytes derived from the ovarian tissues of newborn *** study reports that after the ovarian tissue is transplanted,the retrieved oocytes require a longer time for in vitro maturation(Dinnyes et al.2001).In order to further investigate this technology,in this study,we demonstrate that frozenthawed newborn mouse ovarian tissues can produce mature oocytes after xenograft transplantation into the kidney capsules of adult female mice administered pregnant mare serum gonadotropin(PMSG).In addition,we developed a system that facilitates in vitro

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A Numerical Study on Internal and External flow fields of Synthetic jet Actuator

A Numerical Study on Internal and External flow fields of Sy...

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The fifth International Conference on fluid Mechanics

作者： j.Ding~* P.f.Weng Q.li shanghai Institute of Appl.Math.and Mech. shanghai university shanghai 200072 china

＜正＞The synthetic jet technology is a new active flow control method,which was through injecting small-scale perturbation into incoming flow at key points to realize flow *** this paper,the actuator model was established,which integrates the fields of actuator chamber,actuator exit access and outer flow into one whole flow *** the formation and evolution of synthetic jet were simulated numerically by the finite volume *** effects of actuation frequencies on flow velocities and distributions were *** shows that jet velocities and jet evolutional distances as 300hz of actuation frequency were better than other frequencies investigated in this ***,some computed results are obtained,which offer theory basis for synthetic jet technology applying in airfoil flow control of MAVS.

关键词： synthetic jet actuator flow control

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