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小阴唇整形术:当前小阴唇肥大的治疗方法和简化的分类系统

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中国美容整形外科杂志 2015年第6期26卷 465-469+500-505+470-471页

作者： Saba Motakef jose rodriguez-Feliz Michael T.Chung Michael j.Ingargiola Victor W.Wong Ashit patel 叶美辰高景恒金正民张晨袁继龙罗马琳达大学整形外科奥尔巴尼医学中心整形重建外科杜克大学整形、颌面、口腔外科西奈山医院整形重建外科约翰霍普金斯大学整形重建外科《中国美容整形外科杂志》编辑部大连大学附属新华医院整形外科辽宁省人民医院整形外科

背景小阴唇整形术主要是解决小阴唇肥大引起的功能和外观问题。尽管其手术量逐渐增多,但仍缺少指导手术方法的数据。笔者对相关文献进行系统性复习,旨在制定简单、统一的小阴唇肥大分类表,并对当前小阴唇整形的技术和方法进行总结。... 详细信息

背景小阴唇整形术主要是解决小阴唇肥大引起的功能和外观问题。尽管其手术量逐渐增多,但仍缺少指导手术方法的数据。笔者对相关文献进行系统性复习,旨在制定简单、统一的小阴唇肥大分类表,并对当前小阴唇整形的技术和方法进行总结。方法用pubMed数据库进行系统的文献复习。审阅选定文献中的参考文献,并选出相关的文献。结果本研究对247篇文献进行了复习。根据入选标准,明确评估不同技术的前瞻性和回顾性研究、结果、并发症和患者的满意度,从中选取了19篇文献。共有1949例患者接受小阴唇整形术。总共采用了7种不同的手术方法,包括去上皮、直接切除、“W”形切除、楔形切除、联合切除、Z成形术和激光切除。每种方法的患者满意率为94%100%。所有方法最常见的术后并发症是切口裂开（4.7%）。明确围手术期患者治疗的关键部分。结论小阴唇整形是安全的,且满意率很高。然而,当前的方法仍极其多样化。作者以大阴唇（不是阴道口）到小阴唇外侧缘距离为基础,提出了一种精简的分类系统。围手术期患者治疗的关键部分包括患者的麻醉、切除方法、伤口缝合和术后护理。用标准的分类系统行进一步的随机对照研究,旨在更好地对比不同的技术,选出更好的方法。

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欧洲青少年心肺功能和理想心血管健康的关系

中华高血压杂志 2014年第12期22卷 1173-1173页

作者：刘莉叶鹏 Ruiz jR Huybrechts I Cuenca-García M Artero EG Labayen I Meirhaeghe A Vicente-rodriguez G polito A Manios Y González-Gross M Marcos A Widhalm K Molnar D Kafatos A Sjostrom M Moreno LA Castillo Mj Ortega FB on behalf of the HELENA study group

该研究试图确定欧洲青少年心肺功能和理想心血管健康（由美国心脏协会定义）的相关性,以及是否存在对心血管健康最有利的心肺功能指标阈值。方法：研究纳入来自欧洲9个城市的青少年510人,其中女生259人。通过折返跑20m测试评估心肺功能。

关键词：心血管健康心肺功能青少年欧洲美国心脏协会肺功能指标相关性

Correction:Clinical outcome measures in dementia with Lewy bodies trials:critique and recommendations

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Translational Neurodegeneration 2022年第1期11卷 588-588页

作者： Federico rodriguez-porcel Kathryn A.Wyman-Chick Carla Abdelnour Ruiz jon B.Toledo Daniel Ferreira prabitha Urwyler Rimona S.Weil joseph Kane Andrea pilotto Arvid Rongve Bradley Boeve john-paul Taylor Ian McKeith Dag Aarsland Simon j.G.Lewis the Lewy Body Dementias Clinical Trials Workgroup from the Lewy Body Dementias professional Interest Area-Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment(ISTAART) Department of Neurology Medical University of South Carolina208b Rutledge Av.CharlestonSC 29403USA Department of Neurology Center for Memory and AgingHealthPartnersSaint PaulMNUSA Autonomous University of Barcelona BarcelonaSpain Fixel Institute for Neurological Diseases University of FloridaGainesvilleFLUSA Division of Clinical Geriatrics Department of NeurobiologyCare Sciencesand SocietyCenter for Alzheimer’s ResearchKarolinska InstitutetStockholmSweden Department of Radiology Mayo ClinicRochesterMNUSA ARTORG Center for Biomedical Engineering Research University of BernBernSwitzerland Dementia Research Centre University College LondonLondonUK Centre for public Health Queen’s UniversityBelfastUK Neurology Unit Department of Clinical and Experimental SciencesUniversity of BresciaBresciaItaly Department of Research and Innovation Helse FonnaHaugesund HospitalHaugesundNorway Institute of Clinical Medicine(K1) The University of Ber-genBergenNorway Department of Neurology Center for Sleep MedicineMayo ClinicRochesterMNUSA Translational and Clinical Research Institute Newcastle University Newcastle upon TyneUK Department of Old Age psychiatry Institute of psychiatry psychology and Neuroscience King’s College LondonLondonUK ForeFront parkinson’s Disease Research Clinic Brain and Mind CentreSchool of Medical SciencesUniversity of Sydney100 Mallett StreetCamperdownNSW 2050Australia. 不详

Correction to:Translational Neurodegeneration(2022)11:24 https://***/10.1186/s40035-022-00299-w Following publication of the original article[1],the authors identified some errors in the Additional files *** original ... 详细信息

关键词： degeneration Clinical measures

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沙利度胺治疗慢性盘状红斑狼疮

世界核心医学期刊文摘（皮肤病学分册） 2006年第3期2卷 21-22页

作者： Brocard A. Barbarot S. Milpied B. Stalder j.-F. 周少娜 Clinique Dermatologique CHU Htel-Dieu1place Alexis Ricordeau 44093 Nantes

Introduction. Thalidomide is the second line treatment of chronic lupus erythematosus. The efficacy of this treatment, the minimal effective doses and tolerance are poorly documented in the literature. patients and methods. We present the data of a single-center retrospective studied among 18 patients with chronic lupus erythematosus, treated with thalidomide from 1998 to 2003. Inclusion criteria were: the presence of clinical lesions evoking the disease, confirmed by histological examination and direct immunofluorescence and treatmentwith thalidomide for more than 2 months. Results. Mean age on diagnosis was of 35.8 years. Thalidomide had been initiated a mean of 10.6 years after diagnosis of chronic lupus erythematosus. In 13 out of 18 patients, thalidomide had been prescribed because of failure with prior treatments. Fifteen patients were improved by thalidomide (83.3 p. 100), with 11 (61 p. 100)- complete and 4 (22 p. 100) partial remissions. Two (11 p. 100) patients were stabilized and treatment failed in one. The mean initial dose was of 100 mg/d (50- 150), and maintenance dose was of around 50 mg/d (56 mg/d). The mean follow-up with thalidomide was of 19.4 months. Only one withdrawal due to side effects was reported. The most frequent side effects were: asthenia (33 p. 100), paresthesia (22 p. 100) and weight gain (16.6 p. 100). No side effects were reported in 10 out of 18 patients. Discussion. This study confirms the efficacy of low dose thalidomide in the treatment of chronic lupus erythematosus. In our experience, tolerance to this treatment is good, the most frequent side effect was asthenia, but usually mild. No significant peripheral neuropathy was noted. The fear of side effects, notably neurological, should not delay initiation of thalidomide in the case of failure with current treatments.

关键词：慢性盘状红斑狼疮沙利度胺前治疗红斑狼疮患者直接免疫荧光检查完全缓解组织学检查二线药物纳入标准耐受量

Decline in subarachnoid haemorrhage volumes associated with the first wave of the COVID- 19 pandemic

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Stroke & Vascular Neurology 2021年第4期6卷 542-552,I0026-I0032页

作者： Thanh N Nguyen Diogo C Haussen Muhammad M Qureshi Hiroshi Yamagami Toshiyuki Fujinaka Ossama Y Mansour Mohamad Abdalkader Michael Frankel Zhongming Qiu Allan Taylor pedro Lylyk Omer F Eker Laura Mechtouff Michel piotin Fabricio Oliveira Lima Francisco Mont'Alverne Wazim Izzath Nobuyuki Sakai Mahmoud Mohammaden Alhamza R Al-Bayati Leonardo Renieri Salvatore Mangiafico David Ozretic Vanessa Chalumeau Saima Ahmad Umair Rashid Syed Irteza Hussain Seby john Emma Griffin john Thornton jose Antonio Fiorot Rodrigo Rivera Nadia Hammami Anna M Cervantes-Arslanian Hormuzdiyar H Dasenbrock Huynh Le Vu Viet Quy Nguyen Steven Hetts Romain Bourcier Romain Guile Melanie Walker Malveeka Sharma Don Frei pascal jabbour Nabeel Herial Fawaz Al-Mufti Atilla Ozcan Ozdemir Ozlem Aykac Dheeraj Gandhi Chandril Chugh Charles Matouk pascale Lavoie Randall Edgell Andre Beer-Furlan Michael Chen Monika Killer-Oberpfalzer Vitor Mendes pereira patrick Nicholson Vikram Huded Nobuyuki Ohara Daisuke Watanabe Dong Hun Shin pedro SC Magalhaes Raghid Kikano Santiago Ortega-Gutierrez Mudassir Farooqui Amal Abou-Hamden Tatsuo Amano Ryoo Yamamoto Adrienne Weeks Elena A Cora Rotem Sivan-Hoffmann Roberto Crosa Markus Möhlenbruch Simon Nagel Hosam Al-jehani Sunil A Sheth Victor S Lopez Rivera james E Siegler Achmad Fidaus Sani Ajit S puri Anna Luisa Kuhn Gianmarco Bernava paolo Machi Daniel G Abud Octavio M pontes-Neto Ajay K Wakhloo Barbara Voetsch Eytan Raz Shadi Yaghi Brijesh p Mehta Naoto Kimura Mamoru Murakami jin Soo Lee ji Man Hong Robert Fahed Gregory Walker Eiji Hagashi Steve M Cordina Hong Gee Roh Ken Wong juan F Arenillas Mario Martinez-Galdamez jordi Blasco Alejandro rodriguez Vasquez Luisa Fonseca M Luis Silva Teddy Y Wu Simon john Alex Brehm Marios psychogios William j Mack Matthew Tenser Tatemi Todaka Miki Fujimura Roberta Novakovic jun Deguchi Yuri Sugiura Hiroshi Tokimura Rakesh Khatri Michael Kelly Lissa peeling Yuichi Murayama Hugh Stephen Winters johnny Wong Mohamed Teleb jeremy payne Hiroki Fukuda Kosuke Miyake junsuke Shimbo Yusuke Sug Neurology RadiologyBoston Medical CenterBostonMassachusettsUSA Neurology Marcus Stroke&Neuroscience CenterGrady Memorial HospitalEmory University School of MedicineAtlantaGAUSA Radiology Radiation OncologyBoston University School of MedicineBostonMassachusettsUSA Neurology National Hospital Organization Osaka National HospitalOsakaJapan Neurosurgery National Hospital Organization Osaka National HospitalOsakaJapan Neurology Alexandria UniversityAlexandriaEgypt Radiology Boston Medical CenterBostonMassachusettsUSA Department of Neurology Xinqiao HospitalChongqingChina Neurosurgery University of Cape TownRondeboschWestern CapeSouth Africa Neurosurgery Interventional NeuroradiologyClinica La Sagrada FamiliaBuenos AiresArgentina Neuroradiologie Neurologie VasculaireHospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Neurologie Vasculaire Hospices Civils de LyonLyonAuvergne-Rhône AlpesFrance Interventional Neuroradiology Fondation Ophtalmologique Adolphe de RothschildParisÎle-de FranceFrance Neurology Hospital Geral de FortalezaFortalezaBrazil Interventional Neuroradiology Hospital Geral de FortalezaFortalezaBrazil Neuroradiology Nottingham University Hospitals NHS TrustNottinghamUK Department of Neurosurgery Kobe City Medical Center General HospitalKobeHyogoJapan Interventional Neurovascular Unit University Hospital CareggiFirenzeToscanaItaly Neuroradiology University Hospital Centre ZagrebZagrebCroatia Interventional Neuroradiology Hopital BicetreLe Kremlin-BicetreFrance Stroke and Interventional Neuroradiology Lahore General HospitalLahorePakistan Neurological Institute Cleveland Clinic Abu DhabiAbu DhabiUAE Department of Radiology Beaumont HospitalDublinIreland Neurology Stroke UnitHospital-Estadual CentralVitoriaBrazil Neuroradiology Instituto de Neurocirugia Dr AsengoSantiagoChile Interventional Neuroradiology Institut National de NeurologieTunisTunisia Neurology Boston Medical CenterBostonMassachusettsUSA Neurosurgery Boston Medical Center

Background During the COVID-19 pandemic,decreased volumes of stroke admissions and mechanical thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospitalisations and ruptured aneurysm coiling interventions demonstrated similar *** We conducted a cross-sectional,retrospective,observational study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of SAH,aneurysmal SAH,ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases,10th Revision,*** 3-month cumulative volume,monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period before(1 year and immediately before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control period(1 March-31 May 2019)was obtained to account for seasonal *** There was a significant decline in SAH hospitalisations,with 2044 admissions in the 3 months immediately before and 1585 admissions during the pandemic,representing a relative decline of 22.5%(95%CI−24.3%to−20.7%,pptured aneurysms declined with 1170-1035 procedures,respectively,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)relative *** analysis was noted for aneurysmal SAH hospitalisation decline from 834 to 626 hospitalisations,a 24.9%relative decline(95%CI−28.0%to−22.1%,pptured aneurysm coiling was noted in low coiling volume hospitals of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this *** There was a relative decrease in the volume of SAH hospitalisations,aneurysmal SAH hospitalisations and ruptured aneurysm embolisations during the COVID-19 *** findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial infarction.

关键词： diagnosis representing subarachnoid

早期定量CT灌注参数值的变化预测动脉瘤性蛛网膜下腔出血病人延迟性脑缺血

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国际医学放射学杂志 2016年第6期 699-699页

作者： C.rodriguez-Régent M.Hafsa G.Turc W.B.Hassen M.Edjlali A.Sermet 陈振 Department of Neuroradiology Centre Hospitalier Sainte-AnneUniversité Paris Descartes

摘要目的前瞻性比较动脉瘤性蛛网膜下腔出血(a SAH)病人发病当天和第4天CT灌注(CTp)参数值变化对预后的预测价值。方法比较延迟性脑缺血病人组(DCI+组)

关键词：动脉瘤性蛛网膜下腔出血脑缺血脑血管疾病延迟性病人 CT

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马尾神经根增厚:Krabbe病的常见征象

国际医学放射学杂志 2016年第6期 708-708页

作者： M.Hwang G.Zuccoli A.panigrahy D.rodriguez M.D.poe M.L.Escolar 付继莲 Department of Radiology of University of pittsburgh Medical Center

摘要目的目前,大家通常基于改良Lose评分系统中神经影像表现来评价Krabbe病造血干细胞移植治疗的负担及适应证。这种评价方法囊括了中枢神经系统改变,但却并未考

关键词：增厚马尾神经神经根 Krabbe

失弛缓症患者血清可改变正常人胃底肠肌间神经丛化学信号和NO介导的反应

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世界核心医学期刊文摘（胃肠病学分册） 2006年第8期2卷 34-35页

作者： Bruley Des Varannes S. Chevalier j. pimont S. M. Neunlist 程妍(译) 陈云茹(校) 不详 INSERM U539 University Hospital HStel Dieu Place Alexis Ricordeau 44035 Nantes Cedex France

Background and aims: Achalasia is a disease of unknown aetiology. An immune mechanism has been suggested on the basis of previous morphological observations. The objective of this study was to test whether the serum of achalasia patients could reproduce the phenotype and functional changes that occur with disease progression in an ex vivo human model. Methods: Specimens of normal human fundus were maintained in culture in the presence of serum from patients with achalasia, gastro-oesophageal reflux disease (GORD), or healthy subjects (controls). Immunohistochemical detection of choline acetyltransferase (ChAT), neurone specific enolase (NSE), vasoactive intestinal polypeptide (VIp), nitric oxide synthase (NOS), and substance p was carried out in whole mounts of gastric fundus myenteric plexus. In addition, the effects of achalasia serum on electrical field stimulation (EFS) induced contractions were measured in circular muscle preparations. Results: Serum from achalasia patients did not affect the number of myenteric neurones. Tissues incubated with serum from achalasia patients showed a decrease in the proportion of NOS (- 26% of NSE positive neurones; p = 0.016) and VIp (- 54% ; p = 0.09) neurones, and a concomitant increase in ChAT neurones (+ 16% ; ppared with controls. In contrast, GORD serum did not modify the phenotype of myenteric neurones. Area under the curve of EFS induced relaxations (abolished by N-nitro-L-arginine methyl ester) was significantly decreased following incubation with serum from achalasia patients compared with controls (- 7.6 (2.6) v - 14.5 (5.0); p = 0.036). Conclusions: Serum from achalasia patients can induce phenotypic and functional changes which reproduce the characteristics of the disease. Further identification of putative seric factors and mechanisms involved could lead to the development of novel diagnostic and/or therapeutic strategies in achalasia.

关键词：肠血管活性多肽肌间神经丛失弛缓症收缩反应正常人患者血清 NO介导化学信号胃底

口服异维A酸治疗痤疮后复发危险因素的前瞻性研究

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世界核心医学期刊文摘（皮肤病学分册） 2006年第4期2卷 49-49页

作者： Qué reux G. Volteau C. N' Guyen j.M. Dré noB. 罗素菊徐波 Department of Dermatology - Dieu Centre Hospitalier Ré gional Universitaire de Nantes Place Alexis- Ricordeau FR- 44035 Nantes Cedex 1 FranceProf.

Background: The effectiveness of oral isotretinoin against acne is undeniable. However, few data on the maintenance of effect after treatment termination have been published. Objective: The purpose of the study was to identify the risk factors of relapse after stopping isotretinoin. Method: This prospective open study examined 52 patients with moderate to severe acne at the Dermatological Clinic of the Nantes University Hospital (France). Variables likely to influence relapse were studied using the Cox model. Results: 27 patients (52% ) relapsed after stopping treatment. In multivariate analysis, severe seborrhoea and a high score of inflammatory lesions at the end of the treatment, an early age, a family history of acne, prepubertal acne and acne extended to the trunk were the factors increasing significantly the risk of relapse. Conclusion: Our data allow to define more precisely the profile of acne patients for whom the risk of relapse is highest and who should therefore be followed up quite regularly after treatment termination.

关键词：重度痤疮痤疮患者青春期前皮脂溢大学医院发病年龄南特多变量分析