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j.urnal of Environmental Science and Engineering 2011年第7期5卷 835-843页

作者： H. Rashid j. takemura A.M. Farooqi Department of Civil and Environmental Engineering Tokyo Institute of Technology Tokyo 152-8550 Japan Department of Environmental Sciences Fatima Jinnah Women University Rawalpindi 46000 Pakistan

Due to improper tannery wastewater management in district Kasur Pakistan, groundwater has been reported to be highly contaminated. It was aimed to find out the extent up to which subsurface has contaminated due to chromium in areas adj.cent to the tannery units. Eight （8） soil bores were conducted up to the depth of 30.5 meters and soil samples were tested for total and hexavalent chromium concentrations retained in soil by aqua regia digestion at the every depth of 1.5 meters. Afterwards monitoring wells were installed in these eight （8） bores so as to monitor chromium concentrations in the groundwater on monthly basis. The main source of contamination was considered to be the four （4） drains carrying tanneries effluent therefore samples were collected from these drains so as to observe seasonal variation in chromium concentration.

关键词： Groundwater and soil contamination soil boring monitoring wells chromium tannery wastewater.

Added value of indocyanine green fluorescence imaging in liver surgery

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Hepatobiliary & Pancreatic Diseases International 2022年第4期21卷 310-317页

作者： Nobuyuki takemura Kyoj. Ito Fuyuki Inagaki Fuminori Mihara Norihiro Kokudo Department of Surgery Hepato-Biliary Pancreatic Surgery DivisionNational Center for Global Health and Medicine1-21-1 ToyamaShinjyuku-kuTokyo162-8655Japan

Recently,indocyanine green(ICG)fluorescence imaging has been widely used as a substitute for cholangiography in hepatobiliary surgery,to detect hepatic tumors,for accurate anatomical hepatectomy,and to increase the safety and accuracy of minimally invasive(laparoscopic and robotic)*** clinical relevance of this method has been increasing gradually,as new procedures develop in this *** important roles and the latest added value of ICG fluorescence imaging in liver surgery are discussed in this report.

关键词： Florescence imaging Indocyanine green Hepatocellular carcinoma Colorectal metastasis Hepatectomy Minimally invasive surgery

Niche Differentiation of Phenol-Degrading Microorganisms in UASB Granular Sludge as Revealed by Fluorescence in situ Hybridization

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Engineering 2022年第2期8卷 61-66页

作者： Kengo Kubota Kei Igarashi Masayoshi Yamada Yasuyuki takemura Yu-You Li Hideki Harada Department of Civil and Environmental Engineering Tohoku UniversitySendai 980-8579Japan Department of Urban Environmental Design and Engineering National Institute of TechnologyKagoshima CollegeKirishima 899-5193Japan New Industry Creation Hatchery Center Tohoku UniversitySendai 980-8579Japan

A microbial community structure of granules harvested from an anaerobic sludge blanket reactor treating phenolic wastewater was investigated using fluorescence in situ hybridization(FISH)and clone library *** of Syntrophorhabdaceae and Cryptanaerobacter were observed to be responsible for phenol *** accurate taxonomic assignment of Cryptanaerobacter clones,phylogenetic analysis using nearly full-length 16S ribosomal RNA(rRNA)gene sequences was *** oligonucleotide probes were designed to detect the following three taxonomic groups:Syntrophorhabdaceae,Cryptanaerobacter,and *** analysis of thin sections of anaerobic granules showed a random distribution of bacteria and ***,a well-defined distribution of Syntrophorhabdaceae,Cryptanaerobacter,and Syntrophus was *** and Syntrophus were found on the outer layer of the granules and were closely associated with each other,while Syntrophorhabdaceae was located in the deeper part of the *** specific distribution of the bacteria is most likely due to their metabolic association and affinity for the *** degradation in the granular sludge was observed to be carried out in the following ***,Cryptanaerobacter converts phenol to benzoate,which is then degraded by Syntrophus into *** syntrophic degradation of phenol occurs near the surface of the granule,where the phenol concen-tration is *** the deeper part of the granule,where the phenol concentration is lower,Syntrophorhabdaceae degrades phenol into *** observed that Syntrophorhabdaceae is less likely to produce benzoate as an intermediate to feed the neighboring organisms,which contradicts the theo-ries presented by previous studies.

关键词： Cryptanaerobacter Fluorescence in situ hybridization Anaerobic phenol degradation Syntrophorhabdaceae Syntrophus UASB granular sludge

Hepatitis B virus infection in Indonesia

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World j.urnal of Gastroenterology 2015年第38期21卷 10714-10720页

作者： Shoj. Kubo Shigekazu takemura Shogo Tanaka Hiroj. Shinkawa Takayoshi Nishioka Akinori Nozawa Masahiko Kinoshita Genya Hamano Tokuj. Ito Yorihisa Urata Department of Hepato-Biliary-Pancreatic Surgery Osaka City University Graduate School of Medicine

Approximately 240 million people are chronically infected with hepatitis B virus(HBV),75% of whom reside in Asia. Approximately 600000 of infected patients die each year due to HBV-related diseases or hepatocellular carcinoma(HCC). The endemicity of hepatitis surface antigen in Indonesia is intermediate to high with a geographical difference. The risk of HBV infection is high in hemodialysis(HD) patients,men having sex with men,and health care workers. Occult HBV infection has been detected in various groups such as blood donors,HD patients,and HIVinfected individuals and children. The most common HBV subgenotype in Indonesia is B3 followed by C1. Various novel subgenotypes of HBV have been identified throughout Indonesia,with the novel HBV subgenotypes C6-C16 and D6 being successfully isolated. Although a number of HBV subgenotypes have been discovered in Indonesia,genotyperelated pathogenicity has not yet been elucidated in detail. Therefore,genotype-related differences in the prognosis of liver disease and their effects on treatments need to be determined. A previous study conducted in Indonesia revealed that hepatic steatosis was associated with disease progression. Pre-S2 mutations and mutations at C1638 T and T1753 V in HBV/B3 have been associated with advanced liver diseases including HCC. However,drug resistance to lamivudine,which is prominent in Indonesia,remains obscure. Although the number of studies on HBV in Indonesia has been increasing,adequate databases on HBV infection are limited. We herein provided an overview of the epidemiology and clinical characteristics of HBV infection in Indonesia.

关键词： Hepatitis B virus Epidemiology Prevention Clinical

Carotenoid productivity in human intestinal bacteria Eubacterium limosum and Leuconostoc mesenteroides with functional analysis of their carotenoid biosynthesis genes

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Engineering Microbiology 2024年第2期4卷 1-11页

作者： Wataru Matsumoto Miho takemura Haruka Nanaura Yuta Ami Takashi Maoka Kazutoshi Shindo Shin Kurihara Norihiko Misawa Research Institute for Bioresources and Biotechnology Ishikawa Prefectural University1-308SuematsuNonoich-shi 921-8836Japan Department of Science and Technology on Food Safety Kinki University930 NishimitaniKinokawaWakayama 649-6493Japan Research Institute for Production Development Shimogamo-morimotochoSakyo-kuKyoto 606-0805Japan Department of Food and Nutrition Japan Women’s UniversityMejirodaiBunkyo-kuTokyo 112-8681Japan

The human intestinal microbiota that comprise over 1,000 species thrive in dark and anaerobic *** are recognized for the production of diverse low-molecular-weight metabolites crucial to human health and ***,low-molecular-weight pigments known for their antioxidative activity,are delivered to humans through oral ***,it remains unclear whether human intestinal bacteria biosynthesize carotenoids as part of the in-situ *** this study,we investigated carotenoid synthesis genes in vari-ous human gut and probiotic *** a result,novel candidates,the crtM and crtN genes,were identified in the carbon monoxide-utilizing gut anaerobe Eubacterium limosum and the lactic acid bacterium Leuconostoc mesenteroides *** gene candidates were isolated,introduced into Escherichia coli,which synthesized a carotenoid substrate,and cultured *** analysis of the resulting carotenoids re-vealed that the crtM and crtN gene candidates of *** and *** mediate the production of 4,4′-diaponeurosporene through 15-cis-4,4′-*** of the crtE-homologous genes in these bacteria indicated their non-functionality for C40-carotenoid *** and ***,along with the known carotenogenic lactic acid bacterium Lactiplantibacillus plantarum,were observed to produce no carotenoids under strictly anaerobic *** two lactic acid bacteria synthesized detectable levels of 4,4′-diaponeurosporene under semi-aerobic *** findings highlight that the obligate anaerobe ***-sum retains aerobically functional C30-carotenoid biosynthesis genes,potentially with no immediate self-utility,suggesting an evolutionary direction in carotenoid biosynthesis.(229 words)

关键词： C_(30)carotenoid biosynthesis Obligate anaerobe Human gut bacterium Eubacterium limosum Leuconostoc mesenteroides Lactiplantibacillus plantarum

Advances in tropical cyclone prediction on subseasonal time scales

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Tropical Cyclone Research and Review 2023年第2期12卷 136-150页

作者： Carl j.Schreck III Frederic Vitart Suzana j.Camargo j.anne Camp j.mes Darlow Russell Elsberry j.n Gottschalck Paul Gregory Kurt Hansen j.styn j.ckson Matthew A.j.niga Philip j.Klotzbach Chia-Ying Lee Lindsey Long Masuo Nakano Kazuto takemura Yuhei Takaya Michael j.Ventrice Zhuo Wang Cooperative Institute for Satellite Earth System Studies North Carolina State UniversityUSA European Centre for Medium-Range Weather Forecasts UK Lamont-Doherty Earth Observatory Columbia UniversityUSA Bureau of Meteorology Australia j.int Typhoon Warning Center USA Naval Postgraduate School USA Climate Prediction Center NOAAUSA hNational Research CouncilUSA U.S.Air Force USA Naval Research Laboratory USA Colorado State University USA ERT Inc.USA j.pan Agency for Marine-Earth Science and Technology Japan Climate Prediction Division Japan Meteorological AgencyJapan Meteorological Research Institute Japan Meteorological AgencyJapan DRW Holdings USA University of Illinois at Urbana-Champaign USA

This review describes advances in understanding and forecasting tropical cyclone(TC)subseasonal variability during the past four years.A large effort by the scientiﬁc community has been in understanding the sources of predictability at subseasonal timescales beyond the well-known modulation of TC activity by the Madden-j.lian Oscillation(Mj.).In particular,the strong modulation of TC activity over the western North Paciﬁc by the Boreal Summer Intra-Seasonal Oscillation(BSISO)has been *** has also been realized in understanding the role of tropical-extratropical interactions in improving subseasonal *** addition,several recent publications have shown that extratropical wave breaking may have a role in the genesis and development of *** of multi-model ensemble data sets such as the Subseasonal to Seasonal(S2S)and Subseasonal Experiment(SubX)have shown that the skill of S2S models in predicting the genesis of TCs varies strongly among models and regions but is often tied to their ability to simulate the Mj. and its *** skill in select models has led to an increase over the past four years in the number of forecasting centers issuing subseasonal TC forecasts using various techniques(statistical,statistical-dynamical and dynamical).More extensive veriﬁcation studies have been published over the last four years,but often only for the North Atlantic and eastern North Paciﬁc.

关键词： Tropical cyclones Subseasonal Forecasts Hurricanes Mj.

尾波的场地放大作用及其在S波场地响应中的有效应用

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世界地震译丛 1996年第5期27卷 72-81页

作者： K.Kato K.Aki M.takemura 杨宝仁国家地震局地球物理研究所

本文的主题是,研究是否可由尾波测得特定场地的S波响应。我们使用了南加州4个TERRA地学透镜台(PAS,PFO,SVD和GSC)观测到的1992年兰德斯和大熊地震的余震的记录。由于TERRA地学透镜仪的大动态范围,所记录的S波具有宽频带响应,而尾波的持... 详细信息

本文的主题是,研究是否可由尾波测得特定场地的S波响应。我们使用了南加州4个TERRA地学透镜台(PAS,PFO,SVD和GSC)观测到的1992年兰德斯和大熊地震的余震的记录。由于TERRA地学透镜仪的大动态范围,所记录的S波具有宽频带响应,而尾波的持续时间也长。我们研究了震级从3.3至5.4的65次地震的共708个三分量波形。上述4个台中只有SVD台位于第四纪)中积层上,其余各台均位于白垩纪岩石上。我们首先用频谱比方法(Mayeda等,1991;Koyanagi等,1992)估算了中心频率为0.75,1.0,1.5,2.0,3.0,4.0和6.0Hz,发震时刻70s后的尾波的场地放大因子。我们发现,径向分量的场地放大因子与横向分量的相似。这种相似性是在预料中的,因为尾波包括由各个方向到台站的反向散射波,所得到的是一种各个方向平均了的场地响应。然后,我们用同样资料组中的直达S波部分进行反演(Andrews,1986),以估算S波的场地放大因子。我们发现,尾波场地响应与S波场地响应相当一致,两者之比不超过1.5。这一发现支持了Tsuj.ura(1978)的相同的发现,并且证明了尾波可用于测定特定场地对S波的放大作用。正如Aki(1992)和Zeng(1993)理论上所指出的那样,如果我们假定尾波是由S波所支配的,则这种S波的场地响应与尾波的场地响应的一致是可以理解的。

关键词：地震尾波 S波场地响应场地放大

砂质混合粘土的孔隙水压力和残余变形特性研究

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岩土力学 2005年第3期26卷 342-346页

作者：王桂萱桑野二郎竹村次朗大连大学土木建筑系辽宁大连116024 东京工业大学

以砂质混合粘土为例,通过实施不同初始固结比水平的动力循环荷载试验,考察了土的孔隙水压力和残余变形的发生过程。探讨了当将土的不等向固结分为初始剪应力和等向固结两种应力状态时,孔隙水压力和残余变形的预测方法。提出了归一化的... 详细信息

以砂质混合粘土为例,通过实施不同初始固结比水平的动力循环荷载试验,考察了土的孔隙水压力和残余变形的发生过程。探讨了当将土的不等向固结分为初始剪应力和等向固结两种应力状态时,孔隙水压力和残余变形的预测方法。提出了归一化的孔隙水压力和累积损失能量及残余变形和有效应力比间的关系模型。

关键词：循环荷载试验孔隙水压力累积损失能量残余剪应变

利用显微X光CT对围压和孔隙水压条件下岩石试样的细微成像及其分析(英文)

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岩石力学与工程学报 2008年第12期27卷 2455-2462页

作者：高桥学竹村贵人林为人漆松雪彦日本国立产业技术综合研究所地圈资源与环境研究所日本筑波305-8567 日本大学日本东京154-8550 日本海洋研究开发机构高知岩芯研究所日本南国783-8502 中国地质大学构造与油气资源教育部重点实验室湖北武汉430074

为得到岩石试样在各种围压和孔隙水压条件下的成像并分析其变形,利用显微X光CT系统获得具有5μm高分辨率的三维图像。为此,设计和制造了一个可以对岩石试样同时加围压和孔隙水压的新型压力容器。用此容器,对高20mm、直径10mm的Berea砂岩... 详细信息

为得到岩石试样在各种围压和孔隙水压条件下的成像并分析其变形,利用显微X光CT系统获得具有5μm高分辨率的三维图像。为此,设计和制造了一个可以对岩石试样同时加围压和孔隙水压的新型压力容器。用此容器,对高20mm、直径10mm的Berea砂岩及Noto硅藻泥岩试样施加静水压并使之变形。在各种围压和孔隙水压条件下,每隔15°测试其径向尺寸。试样的平均直径随着有效围压的增长而单调减小。在此,有效围压被定义为围压和孔隙水压之差。随着有效围压的增加,其直径的变化根据不同的方向而不同,即其变形的各向异性特征得到了证实。Noto硅藻泥岩试样的各向异性比最大,达8%。实验结果表明,此显微X光CT方法可用来测试在各种围压和孔隙水压条件下一般方法很难测得、小或不规整试样的变形。

关键词：岩石力学显微X光CT 孔隙水压 X光CT专用压力容器变形各向异性

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HCV相关的肝细胞癌复发后的二次肝切除

中华肝胆外科杂志 2009年第2期15卷 109-109页

作者： Kubo S takemura S Uenishi T 宋继勇(摘) 邹一平(校) 不详解放军总医院第二附属医院北京100091

目前，虽然复发后的肝细胞癌行二次肝切除已经被广泛接受，但二次肝切除的适应证并不确定，作者评估了二次肝切除后的肝癌再次复发的危险因素，从而研究二次肝切除的适应证。入组对象为51例HCV相关的肝癌切除术后复发的再次行肝切除的... 详细信息

目前，虽然复发后的肝细胞癌行二次肝切除已经被广泛接受，但二次肝切除的适应证并不确定，作者评估了二次肝切除后的肝癌再次复发的危险因素，从而研究二次肝切除的适应证。入组对象为51例HCV相关的肝癌切除术后复发的再次行肝切除的病人。16例病人在第一次肝切除前后接受过干扰素治疗。6例病人干扰素治疗后达到长期病毒学应答标准（SVR），

关键词：肝细胞癌肝切除癌复发 HCV 二次肝癌切除人干扰素病毒学应答