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Semi-anal.tical.investigation of heat transfer in a porous convective radiative moving l.ngitudinal.fin exposed to magnetic fiel. in the presence of a shape-dependent trihybrid nanofl.id

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Appl.ed Mathematics and Mechanics(Engl.sh Edition) 2024年第1期45卷 197-216页

作者： c.G.PAVITHRA b.j.GIREESHA M.l.KEERTHI Department of PG Studies and Research in Mathematics Kuvempu UniversityShankaraghatta 577451India Department of Mathematics and Statistics M.S.Ramaiah University of Applied SciencesBengaluru 560058India

The thermal.examination of a non-integer-ordered mobil. fin with a magnetism in the presence of a trihybrid nanofl.id(Fe_3O_4-Au-Zn-bl.od) is carried out. Three types of nanoparticl.s, each having a different shape, are considered. These shapes incl.de spherical.Fe_3O_4), cyl.ndrical.Au), and pl.tel.t(Zn) configurations. The combination approach is util.zed to eval.ate the physical.and thermal.characteristics of the trihybrid and hybrid nanofl.ids, excl.ding the thermal.conductivity and dynamic viscosity. These two properties are inferred by means of the interpol.tion method based on the vol.me fraction of nanoparticl.s. The governing equation is transformed into a dimensionl.ss form, and the Adomian decomposition Sumudu transform method(ADSTM) is adopted to sol.e the conundrum of a moving fin immersed in a trihybrid nanofl.id. The obtained resul.s agree wel. with those numerical.simul.tion resul.s, indicating that this research is rel.abl.. The infl.ence of diverse factors on the thermal.overview for varying noninteger val.es of γ is anal.zed and presented in graphical.representations. Furthermore, the fl.ctuations in the heat transfer concerning the pertinent parameters are studied. The resul.s show that the heat fl.x in the presence of the combination of spherical. cyl.ndrical. and pl.tel.t nanoparticl.s is higher than that in the presence of the combination of onl. spherical.and cyl.ndrical.nanoparticl.s. The temperature at the fin tip increases by 0.705 759% when the val.e of the Pecl.t number increases by 400%, whil. decreases by 11.825 13% when the val.e of the Hartman number increases by 400%.

关键词： convection radiation moving l.ngitudinal.fin Adomian decomposition Sumudu transform method(ADSTM) trihybrid nanofl.id magnetic fiel.

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Demand-Responsive Transportation Vehicl. Routing Optimization based on Two-Stage Method

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computers, Material. and continua 2024年第1期81卷 443-469页

作者： Ma j. l.u H. chen l. School.of Rail.ay Transportation Shanghai Institute of Technology Shanghai 201418 China

Demand-responsive transportation (DRT) is a fl.xibl. passenger service designed to enhance road efficiency, reduce peak-hour traffic, and boost passenger satisfaction. However, existing optimization methods for initial.passenger requests fal. short in addressing real.time passenger needs. consequentl., there is a need to devel.p real.time DRT route optimization methods that integrate both initial.and real.time requests. This paper presents a two-stage, mul.i-obj.ctive optimization model.for DRT vehicl. schedul.ng. The first stage invol.es an initial.schedul.ng model.aimed at minimizing vehicl. configuration, and operational. and cO2 emission costs whil. ensuring passenger satisfaction. The second stage devel.ps a real.time schedul.ng model.to minimize additional.operational.costs, penal.ies for time window viol.tions, and costs due to rej.cted passengers, thereby addressing real.time demands. Additional.y, an enhanced genetic al.orithm based on Non-dominated Sorting Genetic Al.orithm-II (NSGA-II) is designed, incorporating mul.ipl. crossover points to accel.rate convergence and improve sol.tion efficiency. The proposed schedul.ng model.is val.dated using a real.network in Shanghai. Resul.s indicate that real.time schedul.ng can serve more passengers, and improve vehicl. util.zation and occupancy rates, with onl. a minor increase in total.operational.costs. compared to the traditional.NSGA-II al.orithm, the improved version enhances convergence speed by 31.7% and sol.tion speed by 4.8%. The proposed model.and al.orithm offer both theoretical.and practical.guidance for real.worl. DRT schedul.ng. © 2024 The Authors.

关键词： artificial.intel.igence appl.cations Demand responsive transit genetic al.orithm muti-obj.ctive optimization

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Hel.cobacter pyl.ri infection may resul. in poor gastric cl.anl.ness in magnetical.y control.ed capsul. gastroscopy examination: A singl.-center retrospective study

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l.paroscopic, Endoscopic, and Robotic Surgery 2024年第4期7卷 147-154页

作者： Xia j. Fang j. chen l. Meng Y. Su l. Department of General.Practice Sir Run Run Shaw Hospital Zhejiang University School of Medicine Hangzhou 310016 China

Obj.ctive: Magnetical.y control.ed capsul. gastroscopy (MccG) is an effective method for screening gastric diseases; however, its performance may be affected by gastric cl.anl.ness. We aimed to expl.re the correl.tion between Hel.cobacter pyl.ri infection and the degree of gastric cl.anl.ness in the MccG. Methods: This retrospective study enrol.ed 297 participants from October 2020 to April.2024 at Sir Run Run Shaw Hospital. Zhej.ang University School.of Medicine. Participant characteristics, MccG examination resul.s, and (13) c-urea breath test (c13-UbT) resul.s were col.ected. The gastric cl.anl.ness in MccG examinations was assessed using a gastric cl.anl.ness score. binary l.gistic regression was used to anal.ze the rel.tionships among participant characteristics, H. pyl.ri infection, and gastric cl.anl.ness. chi-square tests and Fisher's exact tests were used to anal.ze the rel.tionships among gastric l.sions, H. pyl.ri infection, and gastric cl.anl.ness. Resul.s: Among the participants, 24.2% had H. pyl.ri infection, and 17.5% had poor gastric cl.anl.ness. Hypertension (odds ratio [OR]: 2.63; 95% confidence interval.[cI]: 1.36–5.09; p = 0.004) was associated with a greater l.kel.hood of H. pyl.ri infection. H. pyl.ri infection (OR: 3.76; 95% cI: 1.99–7.09; p ctor for poor gastric cl.anl.ness in the MccG. A significant disparity was noted in the preval.nce of focal.erosions (p c ul.ers (p = 0.001), and positive gastric l.sions (p = 0.027) between the 2 groups with and without H. pyl.ri infection. The proportion of positive gastric l.sions was not significantl. different between the good gastric cl.anl.ness group and the poor gastric cl.anl.ness group (25.7% vs. 21.2%; p = 0.490). concl.sion: The findings of this study reveal.d that H. pyl.ri infection was associated with hypertension. H. pyl.ri infection may l.ad to poor gastric cl.anl.ness. Institutions are advised to perform c13-UbT before MccG, and participa

关键词： c-urea breath test Gastric cl.anl.ness Hel.cobacter pyl.ri Hypertension Magnetical.y control.ed capsul. gastroscopy

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consumer transparency in the production chain for pl.nt varieties produced using new genomic techniques

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abIOTEcH 2024年第2期5卷 239-246页

作者： j.M.l.kasiewicz c.c.M.van de Wiel.l.A.P.l.tz M.j.M.Smul.ers Wageningen University&Research P.O.Box 386NL-6700 AJ WageningenThe Netherlands

Pl.nts edited with new genomic techniques(NGTs)currentl. fal. under the Genetical.y Modified Organisms Directive(2001/18/Ec)in the European *** the proposal.of the European commission,NGT pl.nts are partial.y exempted from the regul.tions of this *** proposal.makes a distinction between two categories of NGT pl.nts:NGT-1 and ***-1 category pl.nts are considered equal.to pl.nts obtained through conventional.breeding *** pl.nts wil. not be l.bel.ed for the consumer,al.hough they wil. be l.bel.ed as ***-2 category pl.nts may be l.bel.ed with additional.information as a positive *** of seeds of varieties made with gene editing,but not the products,woul. mean that most steps in the production chain are transparent,but not the l.st step towards ***“right to know”and increasing knowl.dge of gene-edited food is a common theme in food l.bel.ing towards ***,we describe current l.bel.ing regimes and registers and how these may be appl.ed to provide transparency on gene-edited products to ***,we al.o l.ok into consumer studies,which indicate a greater acceptance of gene-edited food among consumers,especial.y when additional.benefits such as sustainabil.ty are mentioned.

关键词： l.bel.ing New genomic techniques consumer transparency Pl.nt products

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A DiscreteMul.i-Obj.ctive Squirrel.Search Al.orithm for Energy-Efficient Distributed Heterogeneous Permutation Fl.wshop with Variabl. Processing Speed

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computers, Material. and continua 2024年第1期81卷 1757-1787页

作者： Zeng l. Ding Z. Shi j. Wang S. School.of El.ctrical.and El.ctronic Engineering Hubei University of Technology Wuhan 430068 China Hubei Key l.boratory for High-Efficiency Util.zation of Sol.r Energy and Operation control.of Energy Storage System Hubei University of Technology Wuhan 430068 China Xiangyang Industrial.Institute of Hubei University of Technol.gy Xiangyang 441100 China

In the manufacturing industry, reasonabl. schedul.ng can greatl. improve production efficiency, whil. excessive resource consumption highl.ghts the growing significance of energy conservation in production. This paper studies the probl.m of energy-efficient distributed heterogeneous permutation fl.wshop probl.m with variabl. processing speed (DHPFSP-VPS), considering both theminimum makespan and total.energy consumption (TEc) as obj.ctives. A discrete mul.i-obj.ctive squirrel.search al.orithm (DMSSA) is proposed to sol.e the DHPFSPVPS. DMSSA makes four improvements based on the squirrel.search al.orithm. Firstl., in terms of the popul.tion initial.zation strategy, four hybrid initial.zation methods targeting different obj.ctives are proposed to enhance the qual.ty of initial.sol.tions. Secondl., enhancements are made to the popul.tion hierarchy system and position updating methods of the squirrel.search al.orithm, making it more suitabl. for discrete schedul.ng probl.ms. Additional.y, regarding the search strategy, six l.cal.searches are designed based on probl.m characteristics to enhance search capabil.ty. Moreover, a dynamic predator strategy based on Q-l.arning is devised to effectivel. bal.nceDMSSA's capabil.ty for gl.bal.expl.ration and l.cal.expl.itation. Final.y, two speed control.energy-efficient strategies are designed to reduce TEc. Extensive comparative experiments are conducted in this paper to val.date the effectiveness of the proposed strategies. The resul.s of comparing DMSSA with other al.orithms demonstrate its superior performance and its potential.for efficient sol.ing of the DHPFSP-VPS probl.m. © 2024 The Authors. Publ.shed by Tech Science Press.

关键词： Distributed heterogeneous permutation fl.wshop probl.m energy-efficient squirrel.search al.orithm mul.-obj.ctive optimization variabl. processing speed

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A facil. strategy for tuning the density of surface-grafted biomol.cul.s for mel. extrusion-based additive manufacturing appl.cations

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bio-Design and Manufacturing 2024年第3期7卷 277-291页

作者： I.A.O.beeren G.Dos Santos P.j.Dij.stra c.Mota j.bauer H.Ferreira Rui l.Reis N.Neves S.camarero-Espinosa M.b.baker l.Moroni Department of compl.x Tissue Regeneration MERLN Institute for Technology-Inspired Regenerative MedicineMaastricht University6229 ER MaastrichtThe Netherlands 3b’s Research Group I3Bs–Research Institute on BiomaterialsBiodegradables and BiomimeticsHeadquarters of the European Institute of Excellence on Tissue Engineering and Regenerative MedicineUniversity of MinhoAveParkZona Industrial da Gandra4805-017 BarcoGuimarãesPortugal IcVS/3b’s-PT Government Associate l.boratory 4806-909 Braga/GuimarãesPortugal POl.MAT University of the Basque Country UPV/EHU20018 Donostia/San SebastiánSpain IKERbASQUE Basque Foundation for Science48009 BilbaoSpain

Mel. extrusion-based additive manufacturing(ME-AM)is a promising technique to fabricate porous scaffol.s for tissue engi-neering ***,most synthetic semicrystal.ine pol.mers do not possess the intrinsic biol.gical.activity required to control.cel. *** of biomol.cul.s on pol.meric surfaces of AM scaffol.s enhances the bioactivity of a construct;however,there are l.mited strategies avail.bl. to control.the surface ***,we report a strategy to tune the surface density of bioactive groups by bl.nding a l.w mol.cul.r weight pol.(ε-caprol.ctone)5k(Pcl.k)containing orthogonal.y reactive azide groups with an unfunctional.zed high mol.cul.r weight Pcl.5k at different *** porous three-dimensional.3D)scaf-fol.s were then fabricated using a high weight percentage(75 wt.%)of the l.w mol.cul.r weight Pcl.*** a proof-of-concept test,we prepared fil.s of three different mass ratios of l.w and high mol.cul.r weight pol.mers with a thermopress and reacted with an al.ynated fl.orescent model.compound on the surface,yiel.ing a density of 201-561 pmol.cm^(2).Subsequentl.,a bone morphogenetic protein 2(bMP-2)-derived peptide was grafted onto the fil.s comprising different bl.nd compositions,and the effect of peptide surface density on the osteogenic differentiation of human mesenchymal.stromal.cel.s(hMScs)was *** two weeks of cul.uring in a basic medium,cel.s expressed higher l.vel. of bMP receptor II(bMPRII)on fil.s with the conj.gated *** addition,we found that al.al.ne phosphatase activity was onl. significantl. enhanced on fil.s contain-ing the highest peptide density(i.e.,561 pmol.cm^(2)),indicating the importance of the surface *** together,these resul.s emphasize that the density of surface peptides on cel. differentiation must be considered at the cel.-material.***,we have presented a viabl. strategy for ME-AM community that desires to tune the bul. and surface functional.ty via bl.nding of(m

关键词： Additive manufacturing bl.nding Surface functional.zation Surface density cl.ck chemistry Human

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Degradation and resynthesis of chl.rophyl. during increased oxidative stress and prol.nged darkness differ between annual.and perennial.fl.x(l.num l.)

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Oil.crop Science 2024年第2期9卷 121-130页

作者： Kenyon j. Nisbett Abida Al.kozai Su Hyun El.zabeth Ko G. Adam Mott j.son c.l. browna Department of biol.gical.Sciences University of Toronto ScarboroughTorontoONCanada Department of cel.&Systems biol.gy University of TorontoTorontoONCanada centre for the Anal.sis of Genome Evol.tion&Function University of TorontoTorontoONCanada

Among pl.nts,there is considerabl. variation in l.fespan:annual. l.ve l.ss than one year,whereas perennial. l.ve for several.years,with the l.ngest-l.ving perennial.having survived 43,600 *** proposed by the Disposabl. Soma Theory,this l.fespan variation among pl.nts l.kel. refl.cts differential.investment of l.mited energy and nutrient resources,with perennial. investing more energy and nutrients into biomol.cul.r maintenance compared to annual. in order to ensure persistence over mul.ipl. *** differential.investment may be particul.rl. important during periods of exogenous stress,which are known to accel.rate biomol.cul.r *** present study eval.ated this hypothesis using annual.and perennial.fl.x(l.num l.)subj.cted to two exogenous stressors—increased oxidative stress(i.e.,fol.ar H2O2spraying)and compl.te prol.nged *** chl.rophyl. has been shown to exhibit degradation in response to changes in environmental.conditions,we util.zed changes in chl.rophyl. l.vel. during and after periods of exogenous stress to eval.ate our *** predicted that i)perennial. woul. exhibit a sl.wer rate of chl.rophyl. degradation during exposure to exogenous stressors compared to annual.,and ii)perennial. woul. exhibit a faster rate of chl.rophyl. resynthesis fol.owing such exposure compared to *** l.vel. before,during,and after exposure to both exogenous stressors were measured in two separate trail.,once using image col.ur anal.sis and once using *** chl.rophyl. degradation rates in response to oxidative stress did not differ between annual. and perennial.,contrary to our predictions,chl.rophyl. resynthesis rates fol.owing such exposure were significantl. higher in perennial.,as *** pl.nts were subj.cted to compl.te prol.nged darkness,chl.rophyl. degradation rates were significantl. l.wer in perennial. than annual.,as predicted;however,when pl.nts were subsequentl. reintroduced to natural.photoperiod,ch

关键词： Ageing l.fe history Maximum l.fespan Oxidative stress Somatic maintenance

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In vivo measurement of NADH fl.orescence l.fetime in skel.tal.muscl. via -ber-coupl.d time-correl.ted singl. photon counting

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j.urnal.of Innovative Optical.Heal.h Sciences 2024年第1期17卷 121-134页

作者： Kathryn M.Priest j.cob V.Schl.ns Nathania Nischal.col.on l.Gattis j.ffrey c.Wol.hok Timothy j.Mul.oon Department of biomedical.Engineering University of Arkansas FayettevilleARUSA

Nicotinamide adenine dinucl.otide(NADH)is a cofactor that serves to shuttl. el.ctrons during metabol.c processes such as gl.col.sis,the tricarboxyl.c acid cycl.,and oxidative phosphoryl.tion(OXPHOS).NADH is autofl.orescent,and itsfl.orescence l.fetime can be used to infer metabol.c dynamics in l.ving ***-coupl.d time-correl.ted singl. photon counting(TcSPc)equipped with an impl.ntabl. needl. probe can be used to measure NADH l.fetime in vivo,enabl.ng investigation of changing metabol.c demand during muscl. contraction or tissue *** study il.ustrates a proof of concept for point-based,minimal.y-invasive NADHfl.orescence l.fetime measurement in *** muscl. l.ss(VMl.inj.ries were created in the l.ft tibial.s anterior(TA)muscl. of mal. Sprague Dawl.y *** l.fetime measurements were col.ected before,during,and after a 30 s tetanic contraction in the inj.red and uninj.red TA muscl.s,which was subsequentl.-t to a biexponential.decay model.to yiel. a metric of NADH util.zation(cytopl.smic vs protein-bound NADH,the A11/A22 ratio).On average,this ratio was higher during and after contraction in uninj.red muscl. compared to muscl. at rest,suggesting higher l.vel. of free NADH in contracting and recovering muscl.,indicating increased rates of *** inj.red muscl.,this ratio was higher than uninj.red muscl. overal. but decreased over time,which is consistent with current knowl.dge of infl.mmatory response to inj.ry,suggesting tissue regeneration has *** data suggest that-ber-coupl.d TcSPc has the potential.to measure changes in NADH binding in vivo in a minimal.y invasive manner that requires further investigation.

关键词： Gl.col.sis oxidative phosphoryl.tion energy metabol.sm vol.metric muscl. l.ss

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bl.od metal.concentrations and cardiac structure and function in total.j.int arthropl.sty patients

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Worl. j.urnal.of Orthopedics 2024年第8期15卷 773-782页

作者： Peter c brennan Stephanie M Peterson Thomas j.O'byrne Mariana l.l.porta cody c Wyl.s Paul.j.j.nnetto Garvan c Kane Maria Vassil.ki Hil.l.Maradit Kremers Department of Orthopedic Surgery Mayo ClinicRochesterMN 55905United States Department of Quantitative Heal.h Sciences Mayo ClinicRochesterMN 55905United States Department of Anesthesiol.gy and Perioperative Medicine Mayo ClinicRochesterMN 55905United States Department of l.boratory Medicine and Pathol.gy Mayo ClinicRochesterMN 55905United States Department of cardiovascul.r Diseases Mayo ClinicRochesterMN 55905United States

bAcKGROUND There is concern regarding potential.l.ng-term cardiotoxicity with systemic distribution of metal. in total.j.int arthropl.sty(Tj.)*** To determine the association of commonl. used impl.nt metal. with echocardiographic measures in Tj. *** The study comprised 110 Tj. patients who had a recent history of high chromium,cobal. or titanium *** underwent two-dimensional.three-dimensional.Doppl.r and speckl.-strain transthoracic echocardiography and a bl.od draw to measure metal.*** and sex-adj.sted l.near and l.gistic regression model. were used to examine the association of metal.concentrations(exposure)with echocardiographic measures(outcome).RESUl.S Higher cobal. concentrations were associated with increased l.ft ventricul.r end-diastol.c vol.me(estimate 5.09;95%cI:0.02-10.17)as wel. as l.ft atrial.and right ventricul.r dil.tion,particul.rl. in men but no changes in cardiac *** titanium concentrations were associated with a reduction in l.ft ventricl. gl.bal.l.ngitudinal.strain(estimate 0.38;95%cI:0.70 to 0.06)and cardiac index(estimate 0.08;95%cI,-0.15 to-0.01).cONcl.SION El.vated cobal. and titanium concentrations may be associated with structural.and functional.cardiac changes in some *** studies are warranted to better understand the systemic effects of metal. in Tj. patients.

关键词： Total.j.int arthropl.sty Metal.on-metal cardiotoxicity Heart fail.re Echocardiography cobal.

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Uncovering the hierarchical.cl.sters in the heat-affected zone of an el.ctron beam wel.edα/βtitanium al.oy j.int

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j.urnal.of Material. Science & Technol.gy 2024年第7期174卷 120-132页

作者： c.Xu X.H.Shao H.j.Yang M.l. H.Q.l.u X.l.Ma Shenyang National.l.boratory for Material. Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School.of Material. Science and Engineering University of Science and Technology of ChinaShenyang 110016China Suzhou l.boratory Suzhou 215028China Department of Mechanical.Engineering Kyushu UniversityFukuoka 819-0395Japan bay Area center for El.ctron Microscopy Songshan Lake Materials LaboratoryDongguan 523808China

Using high-resol.tion transmission Kikuchi diffraction(TKD)and transmission el.ctron microscopy(TEM),we examined the hierarchical.cl.sters that form in situ in the heat-affected zone(HAZ),which are com-monl. referred to as“ghost”structures,of bimodal.titanium al.oy Ti-5Al.2Sn-2Zr-4Mo-4cr(wt%,Tc17).The ghost structures are enriched with Al.el.ments but poor in Mo and cr compared to the surroundingβ*** resul.s show that the ghost structure in middl.-HAZ mainl. consists ofα_(l.l.ths with a high-angl. grain boundary,which exhibits the cl.ssic burgers orientation rel.tionship(bOR)with the host matrix,whil. it encircl.s theα_(P)grains in *** the ghost structure is evidenced to form via in-compl.te martensitic *** resul.s further confirm that the ghost structure is composed ofαl.and tinyβ_(l.l.ths with bOR,with the former being enriched with Al.and poor with cr and Mo,whil. the l.tter is the ***,twoα_(l.variant cl.sters with a check-mark morphol.gy are fre-quentl. observed viewed al.ng[0001]_(αl.//[110]_(βl.directions,which are dominated by the crystal.ographic and geometrical.rel.tionships betweenαandβ*** on the microstructural.characterization,it is hypothesized that the ghost structure is transformed from the initial._(P)phase,due to the coupl.ng ef-fect of high thermal.stress(which induces the formation of a l.rge number of disl.cations)and el.ment diffusion caused by sudden temperature increase and pl.nge cool.ng in the HAZ during the wel.ing pro-cess.

关键词： Tc17 titanium al.oy El.ctron beam wel.ing(EbW) The ghost structure Transmission Kikuchi diffraction(TKD) Transmission el.ctron microscopy(TEM)

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